Abstract
Compounds of formula (1) comprising a pleuromutilin backbone with a triazole based side-group at C22 are provided. The compounds can be used for treatment of bacterial infections and fungal infections. Importantly, infections caused by multidrug-resistant bacteria, such as methicillin-resistant staphylococcus aureus (MRSA) may be treated effectively.
| Originalsprog | Engelsk |
|---|---|
| IPC | A61K31/4192,A61K31/52,A61P31/04,C07D249/06,C07D403/10,C07D473/02 |
| Patentnummer | WO2021219813 (A1) |
| Journaliseringsdato | 11/04/2021 |
| Land/Område | Danmark |
| Prioritetsdato | 01/05/2020 |
| Prioritetsnummer | EP20200172580 |
| Status | Udgivet - 4. nov. 2021 |