Angiotensin in the kidney: a key to understanding hypertension?

Ulrike Muscha Steckelings, Rainer Rettig, Thomas Unger

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Abstrakt

A crosstransplantation study between genetically matched angiotensin AT1 receptor knockout and wild-type mice revealed that renal AT1 receptors are required for the development of angiotensin II-induced hypertension (). However, in this experimental setting, hypertension-related left ventricular hypertrophy seemed to depend on blood pressure elevation rather than on the expression of AT1 receptors in the heart.
OriginalsprogEngelsk
TidsskriftCell Metabolism
Vol/bind5
Udgave nummer1
Sider (fra-til)7-8
Antal sider2
ISSN1550-4131
DOI
StatusUdgivet - 2007
Udgivet eksterntJa

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