Amplification-free liquid biopsy by fluorescence approach

Jesper Uhd, Anders Okholm, Jargen Kjems, Kira Astakhova

Publikation: Kapitel i bog/rapport/konference-proceedingKonferencebidrag i proceedingsForskningpeer review

Abstrakt

Liquid biopsy is an attractive new paradigm of modern cancer research and clinical oncology. Synergy of fluorescence microscopy with mutation specific molecular probes is a method that we developed for the detection of tumor related circulating DNA, ctDNA. The present detection methods of ctDNA samples include amplification-based techniques that have multiple challenges, are often time consuming and rather expensive. In this work, we successfully applied the hybridization assay and advanced microscopy for the reliable amplification-free detection and quantification of cancer associated mutations in ctDNA.

OriginalsprogEngelsk
TitelBiotech, Biomaterials and Biomedical : TechConnect Briefs 2017
Antal sider4
Vol/bind3
ForlagTechConnect
Publikationsdato2017
Sider106-109
ISBN (Elektronisk)9780998878201
StatusUdgivet - 2017
Begivenhed11th Annual TechConnect World Innovation Conference and Expo, Held Jointly with the 20th Annual Nanotech Conference and Expo, and the 2017 National SBIR/STTR Conference - Washington, USA
Varighed: 14. maj 201717. maj 2017

Konference

Konference11th Annual TechConnect World Innovation Conference and Expo, Held Jointly with the 20th Annual Nanotech Conference and Expo, and the 2017 National SBIR/STTR Conference
LandUSA
ByWashington
Periode14/05/201717/05/2017

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