AMPK inhibitors

Trond Ulven

AMPK inhibitors

Trond Ulven (Opfinder)

Institut for Fysik, Kemi og Farmaci

Publikation: Patent

Abstrakt

The 5'-AMP-activated protein kinase AMPK functions as a master switch to maintain cellular and whole-body energy homeostasis and abnormal activity profiles of AMPK may cause pathological disorders. The present invention relates to a series of compounds (I) based on a pyrrolo[2,3-c]pyridine and a thieno[2,3- c]pyridine scaffold as AMPK inhibitors. In particular, the present invention relates to the synthesis of such compounds and the medical use of such compounds

Originalsprog	Engelsk
IPC	A61K31/4365,A61K31/437,A61P25/00,A61P35/00,C07D471/04,C07D495/04
Patentnummer	WO2019106087A1
Journaliseringsdato	29/11/2018
Land	Danmark
Prioritetsdato	29/11/2017
Prioritetsnummer	EP20170204381
Status	Udgivet - 6. jun. 2019

Dokumenter og links

https://worldwide.espacenet.com/publicationDetails/biblio?DB=EPODOC&II=0&ND=3&adjacent=true&locale=en_EP&FT=D&date=20190606&CC=WO&NR=2019106087A1&KC=A1

Citationsformater

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title = "AMPK inhibitors",

abstract = "The 5'-AMP-activated protein kinase AMPK functions as a master switch to maintain cellular and whole-body energy homeostasis and abnormal activity profiles of AMPK may cause pathological disorders. The present invention relates to a series of compounds (I) based on a pyrrolo[2,3-c]pyridine and a thieno[2,3- c]pyridine scaffold as AMPK inhibitors. In particular, the present invention relates to the synthesis of such compounds and the medical use of such compounds",

author = "Trond Ulven",

year = "2019",

month = jun,

day = "6",

language = "English",

type = "Patent",

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TY - PAT

T1 - AMPK inhibitors

AU - Ulven, Trond

PY - 2019/6/6

Y1 - 2019/6/6

N2 - The 5'-AMP-activated protein kinase AMPK functions as a master switch to maintain cellular and whole-body energy homeostasis and abnormal activity profiles of AMPK may cause pathological disorders. The present invention relates to a series of compounds (I) based on a pyrrolo[2,3-c]pyridine and a thieno[2,3- c]pyridine scaffold as AMPK inhibitors. In particular, the present invention relates to the synthesis of such compounds and the medical use of such compounds

AB - The 5'-AMP-activated protein kinase AMPK functions as a master switch to maintain cellular and whole-body energy homeostasis and abnormal activity profiles of AMPK may cause pathological disorders. The present invention relates to a series of compounds (I) based on a pyrrolo[2,3-c]pyridine and a thieno[2,3- c]pyridine scaffold as AMPK inhibitors. In particular, the present invention relates to the synthesis of such compounds and the medical use of such compounds

M3 - Patent

M1 - WO2019106087A1

Y2 - 2018/11/29

ER -

AMPK inhibitors

Abstrakt

Dokumenter og links

Fingeraftryk

Citationsformater