Alterations in molecular muscle mass regulators after 8 days immobilizing Special Forces mission

J G Jespersen, U R Mikkelsen, A Nedergaard, Jonas Bloch Thorlund, P Schjerling, C Suetta, P A Christensen, Per Aagaard

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In military operations, declined physical capacity can endanger the life of soldiers. During special support and reconnaissance (SSR) missions, Special Forces soldiers sustain 1-2 weeks full-body horizontal immobilization, which impairs muscle strength and performance. Adequate muscle mass and strength are necessary in combat or evacuation situations, which prompt for improved understanding of muscle mass modulation during SSR missions. To explore the molecular regulation of myofiber size during a simulated SSR operation, nine male Special Forces soldiers were biopsied in m. vastus lateralis pre and post 8 days immobilizing restricted prone position. After immobilization, total mammalian target of rapamycin protein was reduced by 42% (P 
TidsskriftScandinavian Journal of Medicine & Science in Sports
Udgave nummer2
Sider (fra-til)175–183
Antal sider9
StatusUdgivet - apr. 2015


Bibliografisk note

Article first published online: 15 JAN 2014