Alcohol drinking, consumption patterns and breast cancer among Danish nurses: a cohort study

Lina S Mørch, Ditte Johansen, Lau C Thygesen, Anne Tjønneland, Ellen Løkkegaard, Claudia Stahlberg, Morten Grønbaek

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Resumé

Udgivelsesdato: 2007-Dec
OriginalsprogEngelsk
TidsskriftEuropean Journal of Public Health
Vol/bind17
Udgave nummer6
Sider (fra-til)624-629
Antal sider6
ISSN1101-1262
DOI
StatusUdgivet - 1. dec. 2007

Fingeraftryk

Alcohol Drinking
Cohort Studies
Nurses
Alcohols
Proportional Hazards Models
Confidence Intervals

Citer dette

Mørch, Lina S ; Johansen, Ditte ; Thygesen, Lau C ; Tjønneland, Anne ; Løkkegaard, Ellen ; Stahlberg, Claudia ; Grønbaek, Morten. / Alcohol drinking, consumption patterns and breast cancer among Danish nurses: a cohort study. I: European Journal of Public Health. 2007 ; Bind 17, Nr. 6. s. 624-629.
@article{b41144a0e2ed11dd990c000ea68e967b,
title = "Alcohol drinking, consumption patterns and breast cancer among Danish nurses: a cohort study",
abstract = "BACKGROUND: The aim of this study was to analyse the impact of alcohol intake and drinking pattern on the risk of breast cancer. METHODS: A total of 17 647 nurses were followed from 1993 until the end of 2001. At baseline participants completed a questionnaire on alcohol intake and other lifestyle-related factors. Data were analysed using Cox's proportional hazard model. RESULTS: During follow-up 457 women were diagnosed with breast cancer. The relative risk of breast cancer was 2.30 [Confidence interval (CI): 1.56-3.39] for alcohol intake of 22-27 drinks per week, compared to 1-3 drinks per week. Among alcohol consumers, weekly alcohol intake increased the risk of breast cancer with 2{\%} for each additional drink consumed. Weekend consumption increased the risk with 4{\%} for each additional drink consumed friday through sunday. Binge drinking of 4-5 drinks the latest weekday increased risk with 55{\%}, compared with consumption of one drink. A possible threshold in risk estimates was found for consumption above 27 drinks per week. CONCLUSIONS: For alcohol consumption above the intake most frequently reported, the risk of breast cancer is increased. The risk is minor for moderate levels but increases for each additional drink consumed during the week. Weekend consumption and binge drinking imply an additional increase in breast cancer risk.",
keywords = "Adult, Aged, Aged, 80 and over, Alcohol Drinking, Breast Neoplasms, Cohort Studies, Denmark, Female, Humans, Middle Aged, Nurses, Proportional Hazards Models, Questionnaires",
author = "M{\o}rch, {Lina S} and Ditte Johansen and Thygesen, {Lau C} and Anne Tj{\o}nneland and Ellen L{\o}kkegaard and Claudia Stahlberg and Morten Gr{\o}nbaek",
year = "2007",
month = "12",
day = "1",
doi = "10.1093/eurpub/ckm036",
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pages = "624--629",
journal = "European Journal of Public Health",
issn = "1101-1262",
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Alcohol drinking, consumption patterns and breast cancer among Danish nurses: a cohort study. / Mørch, Lina S; Johansen, Ditte; Thygesen, Lau C; Tjønneland, Anne; Løkkegaard, Ellen; Stahlberg, Claudia; Grønbaek, Morten.

I: European Journal of Public Health, Bind 17, Nr. 6, 01.12.2007, s. 624-629.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

TY - JOUR

T1 - Alcohol drinking, consumption patterns and breast cancer among Danish nurses: a cohort study

AU - Mørch, Lina S

AU - Johansen, Ditte

AU - Thygesen, Lau C

AU - Tjønneland, Anne

AU - Løkkegaard, Ellen

AU - Stahlberg, Claudia

AU - Grønbaek, Morten

PY - 2007/12/1

Y1 - 2007/12/1

N2 - BACKGROUND: The aim of this study was to analyse the impact of alcohol intake and drinking pattern on the risk of breast cancer. METHODS: A total of 17 647 nurses were followed from 1993 until the end of 2001. At baseline participants completed a questionnaire on alcohol intake and other lifestyle-related factors. Data were analysed using Cox's proportional hazard model. RESULTS: During follow-up 457 women were diagnosed with breast cancer. The relative risk of breast cancer was 2.30 [Confidence interval (CI): 1.56-3.39] for alcohol intake of 22-27 drinks per week, compared to 1-3 drinks per week. Among alcohol consumers, weekly alcohol intake increased the risk of breast cancer with 2% for each additional drink consumed. Weekend consumption increased the risk with 4% for each additional drink consumed friday through sunday. Binge drinking of 4-5 drinks the latest weekday increased risk with 55%, compared with consumption of one drink. A possible threshold in risk estimates was found for consumption above 27 drinks per week. CONCLUSIONS: For alcohol consumption above the intake most frequently reported, the risk of breast cancer is increased. The risk is minor for moderate levels but increases for each additional drink consumed during the week. Weekend consumption and binge drinking imply an additional increase in breast cancer risk.

AB - BACKGROUND: The aim of this study was to analyse the impact of alcohol intake and drinking pattern on the risk of breast cancer. METHODS: A total of 17 647 nurses were followed from 1993 until the end of 2001. At baseline participants completed a questionnaire on alcohol intake and other lifestyle-related factors. Data were analysed using Cox's proportional hazard model. RESULTS: During follow-up 457 women were diagnosed with breast cancer. The relative risk of breast cancer was 2.30 [Confidence interval (CI): 1.56-3.39] for alcohol intake of 22-27 drinks per week, compared to 1-3 drinks per week. Among alcohol consumers, weekly alcohol intake increased the risk of breast cancer with 2% for each additional drink consumed. Weekend consumption increased the risk with 4% for each additional drink consumed friday through sunday. Binge drinking of 4-5 drinks the latest weekday increased risk with 55%, compared with consumption of one drink. A possible threshold in risk estimates was found for consumption above 27 drinks per week. CONCLUSIONS: For alcohol consumption above the intake most frequently reported, the risk of breast cancer is increased. The risk is minor for moderate levels but increases for each additional drink consumed during the week. Weekend consumption and binge drinking imply an additional increase in breast cancer risk.

KW - Adult

KW - Aged

KW - Aged, 80 and over

KW - Alcohol Drinking

KW - Breast Neoplasms

KW - Cohort Studies

KW - Denmark

KW - Female

KW - Humans

KW - Middle Aged

KW - Nurses

KW - Proportional Hazards Models

KW - Questionnaires

U2 - 10.1093/eurpub/ckm036

DO - 10.1093/eurpub/ckm036

M3 - Journal article

VL - 17

SP - 624

EP - 629

JO - European Journal of Public Health

JF - European Journal of Public Health

SN - 1101-1262

IS - 6

ER -