A Danish national population-based cohort study of synthetic midurethral slings, 2007–2011

Margrethe Foss Hansen*, Gunnar Lose, Hrefna Bóel Sigurdardòttir, Kim Oren Gradel

*Kontaktforfatter for dette arbejde

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

1 Downloads (Pure)

Resumé

Introduction and hypothesis: Synthetic midurethral slings (MUSs) have shown similar cure rates in several short- and medium-term follow-up studies. Recently, long-term follow-up studies have indicated that the cure rate is higher following the retropubic midurethral sling (RPMUS) compared with the transobturator midurethral sling (TOMUS) procedure. The aim was to evaluate the efficacy of synthetic MUSs and to examine the influence of department and surgeon volume and patient-related factors on the cure rate of synthetic MUSs. Methods: A retrospective cohort study based on a national population over a 5-year period (2007–2011) using data from the Danish Urogynaecological Database (DugaBase). Results: A total of 4519 women with first-time MUS were registered in the DugaBase. Cure was achieved in 1242/1639 (75.78%) at a 3-month follow-up. RPMUSs were more frequently in use in high-volume departments compared with the other departments and more often implanted by high- than low-volume surgeons. Women treated by a medium- (adjusted OR 1.82; 95% CI 1.01–3.28, “frequency”) or high-volume surgeon (1.98; 1.18–3.32, “frequency”) had an increased probability of cure compared with women treated by a low-volume surgeon. The difference was only significant for women who received a TOMUS. Conclusions: This national population-based cohort study confirmed a high cure rate of synthetic MUSs at short-term follow-up. It is the largest study to indicate a learning curve for TOMUS. Patients were not actively involved in which synthetic MUS was to be performed as the choice of surgical option was made at the departmental level.

OriginalsprogEngelsk
TidsskriftInternational Urogynecology Journal
Vol/bind30
Udgave nummer5
Sider (fra-til)733-741
ISSN0937-3462
DOI
StatusUdgivet - maj 2019

Fingeraftryk

Suburethral Slings
Cohort Studies
Population
Databases
Retrospective Studies

Citer dette

Hansen, Margrethe Foss ; Lose, Gunnar ; Sigurdardòttir, Hrefna Bóel ; Gradel, Kim Oren. / A Danish national population-based cohort study of synthetic midurethral slings, 2007–2011. I: International Urogynecology Journal. 2019 ; Bind 30, Nr. 5. s. 733-741.
@article{f3ee0969a7184fef9c579b152f28cbec,
title = "A Danish national population-based cohort study of synthetic midurethral slings, 2007–2011",
abstract = "Introduction and hypothesis: Synthetic midurethral slings (MUSs) have shown similar cure rates in several short- and medium-term follow-up studies. Recently, long-term follow-up studies have indicated that the cure rate is higher following the retropubic midurethral sling (RPMUS) compared with the transobturator midurethral sling (TOMUS) procedure. The aim was to evaluate the efficacy of synthetic MUSs and to examine the influence of department and surgeon volume and patient-related factors on the cure rate of synthetic MUSs. Methods: A retrospective cohort study based on a national population over a 5-year period (2007–2011) using data from the Danish Urogynaecological Database (DugaBase). Results: A total of 4519 women with first-time MUS were registered in the DugaBase. Cure was achieved in 1242/1639 (75.78{\%}) at a 3-month follow-up. RPMUSs were more frequently in use in high-volume departments compared with the other departments and more often implanted by high- than low-volume surgeons. Women treated by a medium- (adjusted OR 1.82; 95{\%} CI 1.01–3.28, “frequency”) or high-volume surgeon (1.98; 1.18–3.32, “frequency”) had an increased probability of cure compared with women treated by a low-volume surgeon. The difference was only significant for women who received a TOMUS. Conclusions: This national population-based cohort study confirmed a high cure rate of synthetic MUSs at short-term follow-up. It is the largest study to indicate a learning curve for TOMUS. Patients were not actively involved in which synthetic MUS was to be performed as the choice of surgical option was made at the departmental level.",
keywords = "Department volume, Learning curve, Midurethral slings, Retropubic midurethral sling, Surgeon volume, Transobturator midurethral sling",
author = "Hansen, {Margrethe Foss} and Gunnar Lose and Sigurdard{\`o}ttir, {Hrefna B{\'o}el} and Gradel, {Kim Oren}",
year = "2019",
month = "5",
doi = "10.1007/s00192-018-3719-y",
language = "English",
volume = "30",
pages = "733--741",
journal = "International Urogynecology Journal",
issn = "0937-3462",
publisher = "Springer",
number = "5",

}

A Danish national population-based cohort study of synthetic midurethral slings, 2007–2011. / Hansen, Margrethe Foss; Lose, Gunnar; Sigurdardòttir, Hrefna Bóel; Gradel, Kim Oren.

I: International Urogynecology Journal, Bind 30, Nr. 5, 05.2019, s. 733-741.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

TY - JOUR

T1 - A Danish national population-based cohort study of synthetic midurethral slings, 2007–2011

AU - Hansen, Margrethe Foss

AU - Lose, Gunnar

AU - Sigurdardòttir, Hrefna Bóel

AU - Gradel, Kim Oren

PY - 2019/5

Y1 - 2019/5

N2 - Introduction and hypothesis: Synthetic midurethral slings (MUSs) have shown similar cure rates in several short- and medium-term follow-up studies. Recently, long-term follow-up studies have indicated that the cure rate is higher following the retropubic midurethral sling (RPMUS) compared with the transobturator midurethral sling (TOMUS) procedure. The aim was to evaluate the efficacy of synthetic MUSs and to examine the influence of department and surgeon volume and patient-related factors on the cure rate of synthetic MUSs. Methods: A retrospective cohort study based on a national population over a 5-year period (2007–2011) using data from the Danish Urogynaecological Database (DugaBase). Results: A total of 4519 women with first-time MUS were registered in the DugaBase. Cure was achieved in 1242/1639 (75.78%) at a 3-month follow-up. RPMUSs were more frequently in use in high-volume departments compared with the other departments and more often implanted by high- than low-volume surgeons. Women treated by a medium- (adjusted OR 1.82; 95% CI 1.01–3.28, “frequency”) or high-volume surgeon (1.98; 1.18–3.32, “frequency”) had an increased probability of cure compared with women treated by a low-volume surgeon. The difference was only significant for women who received a TOMUS. Conclusions: This national population-based cohort study confirmed a high cure rate of synthetic MUSs at short-term follow-up. It is the largest study to indicate a learning curve for TOMUS. Patients were not actively involved in which synthetic MUS was to be performed as the choice of surgical option was made at the departmental level.

AB - Introduction and hypothesis: Synthetic midurethral slings (MUSs) have shown similar cure rates in several short- and medium-term follow-up studies. Recently, long-term follow-up studies have indicated that the cure rate is higher following the retropubic midurethral sling (RPMUS) compared with the transobturator midurethral sling (TOMUS) procedure. The aim was to evaluate the efficacy of synthetic MUSs and to examine the influence of department and surgeon volume and patient-related factors on the cure rate of synthetic MUSs. Methods: A retrospective cohort study based on a national population over a 5-year period (2007–2011) using data from the Danish Urogynaecological Database (DugaBase). Results: A total of 4519 women with first-time MUS were registered in the DugaBase. Cure was achieved in 1242/1639 (75.78%) at a 3-month follow-up. RPMUSs were more frequently in use in high-volume departments compared with the other departments and more often implanted by high- than low-volume surgeons. Women treated by a medium- (adjusted OR 1.82; 95% CI 1.01–3.28, “frequency”) or high-volume surgeon (1.98; 1.18–3.32, “frequency”) had an increased probability of cure compared with women treated by a low-volume surgeon. The difference was only significant for women who received a TOMUS. Conclusions: This national population-based cohort study confirmed a high cure rate of synthetic MUSs at short-term follow-up. It is the largest study to indicate a learning curve for TOMUS. Patients were not actively involved in which synthetic MUS was to be performed as the choice of surgical option was made at the departmental level.

KW - Department volume

KW - Learning curve

KW - Midurethral slings

KW - Retropubic midurethral sling

KW - Surgeon volume

KW - Transobturator midurethral sling

U2 - 10.1007/s00192-018-3719-y

DO - 10.1007/s00192-018-3719-y

M3 - Journal article

C2 - 30073484

AN - SCOPUS:85051678489

VL - 30

SP - 733

EP - 741

JO - International Urogynecology Journal

JF - International Urogynecology Journal

SN - 0937-3462

IS - 5

ER -