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A community proposal to integrate proteomics activities in ELIXIR

  • Juan Antonio Vizcaíno*
  • , Mathias Walzer
  • , Rafael C. Jiménez
  • , Wout Bittremieux
  • , David Bouyssié
  • , Christine Carapito
  • , Fernando Corrales
  • , Myriam Ferro
  • , Albert J.R. Heck
  • , Peter Horvatovich
  • , Martin Hubalek
  • , Lydie Lane
  • , Kris Laukens
  • , Fredrik Levander
  • , Frederique Lisacek
  • , Petr Novak
  • , Magnus Palmblad
  • , Damiano Piovesan
  • , Alfred Pühler
  • , Veit Schwämmle
  • Dirk Valkenborg, Merlijn van Rijswijk, Jiri Vondrasek, Martin Eisenacher, Lennart Martens, Oliver Kohlbacher
*Kontaktforfatter
  • Wellcome Trust Genome Campus
  • ELIXIR Hub
  • University of Antwerp
  • French National Institute of Health and Medical Research
  • National Center for Biotechnology
  • Utrecht University
  • Netherlands Proteomics Center
  • University of Groningen
  • The Czech Academy of Sciences
  • Swiss Institute of Bioinformatics
  • Geneva University Hospitals
  • Lund University
  • University of Geneva
  • Leiden University
  • University of Padova
  • Bielefeld University
  • Hasselt University
  • Flemish Institute of Technological Research
  • Netherlands Metabolomics Centre
  • Dutch Techcentre for Life Sciences / ELIXIR-NL
  • Ruhr University Bochum
  • Ghent University
  • Eberhard Karls University of Tübingen
  • Max Planck Institute for Developmental Biology

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Abstract

Computational approaches have been major drivers behind the progress of proteomics in recent years. The aim of this white paper is to provide a framework for integrating computational proteomics into ELIXIR in the near future, and thus to broaden the portfolio of omics technologies supported by this European distributed infrastructure. This white paper is the direct result of a strategy meeting on 'The Future of Proteomics in ELIXIR' that took place in March 2017 in Tübingen (Germany), and involved representatives of eleven ELIXIR nodes. These discussions led to a list of priority areas in computational proteomics that would complement existing activities and close gaps in the portfolio of tools and services offered by ELIXIR so far. We provide some suggestions on how these activities could be integrated into ELIXIR's existing platforms, and how it could lead to a new ELIXIR use case in proteomics. We also highlight connections to the related field of metabolomics, where similar activities are ongoing. This white paper could thus serve as a starting point for the integration of computational proteomics into ELIXIR. Over the next few months we will be working closely with all stakeholders involved, and in particular with other representatives of the proteomics community, to further refine this paper.

OriginalsprogEngelsk
Artikelnummer875
TidsskriftF1000Research
Vol/bind6
Antal sider11
ISSN2046-1402
DOI
StatusUdgivet - 2017

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