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2020

Association of Genomic Domains in BRCA1 and BRCA2 with Prostate Cancer Risk and Aggressiveness

Patel, V. L., Busch, E. L., Friebel, T. M., Cronin, A., Leslie, G., McGuffog, L., Adlard, J., Agata, S., Agnarsson, B. A., Ahmed, M., Aittomäki, K., Alducci, E., Andrulis, I. L., Arason, A., Arnold, N., Artioli, G., Arver, B., Auber, B., Azzollini, J., Balmaña, J. & 243 flere, Barkardottir, R. B., Barnes, D. R., Barroso, A., Barrowdale, D., Belotti, M., Benitez, J., Bertelsen, B., Blok, M. J., Bodrogi, I., Bonadona, V., Bonanni, B., Bondavalli, D., Boonen, S. E., Borde, J., Borg, A., Bradbury, A. R., Brady, A., Brewer, C., Brunet, J., Buecher, B., Buys, S. S., Cabezas-Camarero, S., Caldés, T., Caliebe, A., Caligo, M. A., Calvello, M., Campbell, I. G., Carnevali, I., Carrasco, E., Chan, T. L., Chu, A. T. W., Chung, W. K., Claes, K. B. M., Collaborators, G. S., Collaborators, E., Cook, J., Cortesi, L., Couch, F. J., Daly, M. B., Damante, G., Darder, E., Davidson, R., de la Hoya, M., Della Puppa, L., Dennis, J., Díez, O., Ding, Y. C., Ditsch, N., Domchek, S. M., Donaldson, A., Dworniczak, B., Easton, D. F., Eccles, D. M., Eeles, R. A., Ehrencrona, H., Ejlertsen, B., Engel, C., Evans, D. G., Faivre, L., Faust, U., Feliubadaló, L., Foretova, L., Fostira, F., Fountzilas, G., Frost, D., García-Barberán, V., Garre, P., Gauthier-Villars, M., Géczi, L., Gehrig, A., Gerdes, A-M., Gesta, P., Giannini, G., Glendon, G., Godwin, A. K., Goldgar, D. E., Greene, M. H., Gutierrez-Barrera, A. M., Hahnen, E., Hamann, U., Hauke, J., Herold, N., Hogervorst, F. B. L., Honisch, E., Hopper, J. L., Hulick, P. J., Investigators, KC., Investigators, H., Izatt, L., Jager, A., James, P., Janavicius, R., Jensen, U. B., Jensen, T. D., Johannsson, O. T., John, E. M., Joseph, V., Kang, E., Kast, K., Kiiski, J. I., Kim, S-W., Kim, Z., Ko, K-P., Konstantopoulou, I., Kramer, G., Krogh, L., Kruse, T. A., Kwong, A., Larsen, M., Lasset, C., Lautrup, C., Lázaro, C., Lee, J., Lee, J. W., Lee, M. H., Lemke, J., Lesueur, F., Liljegren, A., Lindblom, A., Llovet, P., Lopez-Fernández, A., Lopez-Perolio, I., Lorca, V., Loud, J. T., Ma, E. S. K., Mai, P. L., Manoukian, S., Mari, V., Martin, L., Matricardi, L., Mebirouk, N., Medici, V., Meijers-Heijboer, H. E. J., Meindl, A., Mensenkamp, A. R., Miller, C., Molina Gomes, D., Montagna, M., Mooij, T. M., Moserle, L., Mouret-Fourme, E., Mulligan, A. M., Nathanson, K. L., Navratilova, M., Nevanlinna, H., Niederacher, D., Cilius Nielsen, F. C., Nikitina-Zake, L., Offit, K., Olah, E., Olopade, O. I., Ong, K-R., Osorio, A., Ott, C-E., Palli, D., Park, S. K., Parsons, M. T., Pedersen, I. S., Peissel, B., Peixoto, A., Pérez-Segura, P., Peterlongo, P., Høgh Petersen, A., Porteous, M. E., Pujana, M. A., Radice, P., Ramser, J., Rantala, J., Rashid, M. U., Rhiem, K., Rizzolo, P., Robson, M. E., Rookus, M. A., Rossing, C. M., Ruddy, K. J., Santos, C., Saule, C., Scarpitta, R., Schmutzler, R. K., Schuster, H., Senter, L., Seynaeve, C. M., Shah, P. D., Sharma, P., Shin, V. Y., Silvestri, V., Simard, J., Singer, C. F., Skytte, A-B., Snape, K., Solano, A. R., Soucy, P., Southey, M. C., Spurdle, A. B., Steele, L., Steinemann, D., Stoppa-Lyonnet, D., Stradella, A., Sunde, L., Sutter, C., Tan, Y. Y., Teixeira, M. R., Teo, S. H., Thomassen, M., Tibiletti, M. G., Tischkowitz, M., Tognazzo, S., Toland, A. E., Tommasi, S., Torres, D., Toss, A., Trainer, A. H., Tung, N., van Asperen, C. J., van der Baan, F. H., van der Kolk, L. E., van der Luijt, R. B., van Hest, L. P., Varesco, L., Varon-Mateeva, R., Viel, A., Vierstraete, J., Villa, R., von Wachenfeldt, A., Wagner, P., Wang-Gohrke, S., Wappenschmidt, B., Weitzel, J. N., Wieme, G., Yadav, S., Yannoukakos, D., Yoon, S-Y., Zanzottera, C., Zorn, K. K., D'Amico, A. V., Freedman, M. L., Pomerantz, M. M., Chenevix-Trench, G., Antoniou, A. C., Neuhausen, S. L., Ottini, L., Nielsen, H. R. & Rebbeck, T. R., 1. feb. 2020, I : Cancer research. 80, 3, s. 624-638

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Prostatic Neoplasms
Confidence Intervals
Prostate Cancer, Hereditary, 7
Mutation
Genetic Association Studies

Innate signaling within the central nervous system recruits protective neutrophils

Khorooshi, R., Marczynska, J., Dieu, R. S., Wais, V., Hansen, C. R., Kavan, S., Thomassen, M., Burton, M., Kruse, T., Webster, G. A. & Owens, T., 8. jan. 2020, I : Acta Neuropathologica Communications. 8, 1, s. 2

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Neutrophils
Central Nervous System
Autoimmune Experimental Encephalomyelitis
Cisterna Magna
Cytophagocytosis
2019
40 Downloads (Pure)

A functional genetic screen identifies the Mediator complex as essential for SSX2-induced senescence

Brückmann, N. H., Bennedsen, S. N., Duijf, P. H. G., Terp, M. G., Thomassen, M., Larsen, M., Pedersen, C. B., Kruse, T., Alcaraz, N., Ditzel, H. J. & Gjerstorff, M. F., 6. nov. 2019, I : Cell Death & Disease. 10, 11, 12 s., 841.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

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Neoplasms
Epirubicin
Proteins
Cell Aging
Nevus

CFP suppresses breast cancer cell growth by TES-mediated upregulation of the transcription factor DDIT3

Block, I., Müller, C., Sdogati, D., Pedersen, H., List, M., Jaskot, A. M., Syse, S. D., Lund Hansen, P., Schmidt, S., Christiansen, H., Casella, C., Bering Olsen, S., Blomstrøm, M. M., Riedel, A., Thomassen, M., Kruse, T. A., Karlskov Hansen, S. W., Kioschis, P. & Mollenhauer, J., 6. jun. 2019, I : Oncogene. 38, 23, s. 4560-4573

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Properdin
Up-Regulation
Growth
Neoplasms
Mutation

Effect of thrombopoietin receptor agonists on markers of coagulation and P-selectin in patients with immune thrombocytopenia

Garabet, L., Ghanima, W., Monceyron Jonassen, C., Skov, V., Holst, R., Mowinckel, M-C., Hans, C. H., Torben, A. K., Thomassen, M., Liebman, H., Bussel, J. B. & Sandset, P. M., 17. feb. 2019, I : Platelets. 30, 2, s. 206-212

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Thrombopoietin Receptors
P-Selectin
Idiopathic Thrombocytopenic Purpura
Plasminogen Activator Inhibitor 1
Platelet Count

Epigenetic association analysis of clinical sub-phenotypes in patients with polycystic ovary syndrome (PCOS)

Jacobsen, V. M., Li, S., Wang, A., Zhu, D., Liu, M., Thomassen, M., Kruse, T. A. & Tan, Q., 3. aug. 2019, I : Gynecological Endocrinology. 35, 8, s. 691-694

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

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Polycystic Ovary Syndrome
Epigenomics
DNA Methylation
HLA-G Antigens
Chromosomes, Human, Pair 19

Evaluation of tumor-infiltrating lymphocytes and association with prognosis in BRCA-mutated breast cancer

Sønderstrup, I. M. H., Jensen, M. B., Ejlertsen, B., Eriksen, J. O., Gerdes, A. M., Kruse, T. A., Larsen, M. J., Thomassen, M. & Laenkholm, A. V., 4. mar. 2019, I : Acta Oncologica. 58, 3, s. 363-370

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Tumor-Infiltrating Lymphocytes
Mutation
Germ-Line Mutation
Risk Reduction Behavior
Paraffin

Genomic Profiling of a Phase III Clinical Trial of Interferon Versus Hydroxyurea in MPN Patients Reveals Mutation-Specific and Treatment-Specific Patterns of Response

Knudsen, T. A., Skov, V., Werner, L., Duke, W., Gibson, C. J., Nag, A., Thorner, A. R., Wollison, B., Lund Hansen, D., Larsen, T. S., Ellervik, C., El Fassi, D., de Stricker, K., Ocias, L. F., Brabrand, M., Weiss Bjerrum, O., Overgaard, U. M., Frederiksen, M., Kielsgaard Kristensen, T., Kruse, T. A. & 11 flere, Thomassen, M., Mourits-Andersen, T., Severinsen, M. T., Jesper, S., Starklint, J., Møller, P., Neuberg, D. S., Kjær, L., Hasselbalch, H. C., Coleman Lindsley, R. & Mullally, A., 9. dec. 2019.

Publikation: Konferencebidrag uden forlag/tidsskriftPosterForskningpeer review

Genomic Profiling of a Phase III Clinical Trial of Interferon Versus Hydroxyurea in MPN Patients Reveals Mutation-Specific and Treatment-Specific Patterns of Response

Knudsen, T. A., Skov, V., Werner, L., Duke, W., Gibson, C. J., Nag, A., Thorner, A. R., Wollison, B., Lund Hansen, D., Larsen, T. S., Ellervik, C., El Fassi, D., de Stricker, K., Ocias, L. F., Brabrand, M., Weiss Bjerrum, O., Overgaard, U. M., Frederiksen, M., Kielsgaard Kristensen, T., Kruse, T. A. & 11 flere, Thomassen, M., Mourits-Andersen, H. T., Severinsen, M. T., Jesper, S., Starklint, J., Møller, P., Neuberg, D. S., Kjær, L., Hasselbalch, H. C., Coleman Lindsley, R. & Mullally, A., 13. nov. 2019, I : Blood. 134, Supplement 1, 4202.

Publikation: Bidrag til tidsskriftKonferenceabstrakt i tidsskriftForskningpeer review

Genomisk medicin og kunstig intelligens

Kruse, T. A., Larsen, M. J., Tan, Q., Andersen, L. & Thomassen, M., 1. apr. 2019, I : Ugeskrift for Laeger. 181, 7A, V02190085.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Medicine
Datasets
Clinical Decision-Making

Large scale multifactorial likelihood quantitative analysis of BRCA1 and BRCA2 variants: An ENIGMA resource to support clinical variant classification

Lautrup, C. K. & kConFab Investigators, sep. 2019, I : Human Mutation. 40, 9, s. 1557-1578

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Virulence
Computational Biology
Pathology
Messenger RNA
Research

Molecular profiling reveals highly de-regulated insulin growth factor binding proteins in patients with myelofibrosis and related neoplasms

Skov, V., Thomassen, M., Kjær, L., Riley, C. H., Larsen, T. S., Weiss Bjerrum, O., Kruse, T. A. & Hasselbalch, H. C., 14. jun. 2019.

Publikation: Konferencebidrag uden forlag/tidsskriftPosterForskningpeer review

29 Downloads (Pure)

Molecular signature of different lesion types in the brain white matter of patients with progressive multiple sclerosis

Elkjaer, M. L., Frisch, T., Reynolds, R., Kacprowski, T., Burton, M., Kruse, T. A., Thomassen, M., Baumbach, J. & Illes, Z., 11. dec. 2019, I : Acta Neuropathologica Communications. 7, 17 s., 205.

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Microglia
Endophenotypes
Heat-Shock Response
White Matter
Heat-Shock Proteins
56 Downloads (Pure)

Subtypes in BRCA-mutated breast cancer

Sønderstrup, I., Jensen, M. B., Ejlertsen, B., Eriksen, J. O., Gerdes, A. M., Kruse, T. A., Larsen, M. J., Thomassen, M. & Lænkholm, A. V., 1. feb. 2019, I : Human Pathology. 84, s. 192-201

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

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Germ Cells
Germ-Line Mutation
Neoplasms
Hormones
Breast Cancer 3

The Optimal Sequencing Depth of Tumor Biopsies for Identifying Clonal Cell Populations

Tabatabaeifar, S., Larsen, M. J., Thomassen, M., Larsen, S. R., Kruse, T. A. & Sørensen, J. A., 1. sep. 2019, I : Journal of Molecular Diagnostics. 21, 5, s. 790-795

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Population
Neoplasms
Research Personnel
DNA Sequence Analysis
Cluster Analysis
10 Downloads (Pure)
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DNA
Neoplasms
Mutation
Residual Neoplasm
2018

A Danish national effort of BRCA1/2 variant classification

Pedersen, I. S., Schmidt, A. Y., Bertelsen, B., Ernst, A., Andersen, C. L. T., Kruse, T., Rossing, M. & Thomassen, M., 2. jan. 2018, I : Acta Oncologica. 57, 1, s. 159-162

Publikation: Bidrag til tidsskriftKommentar/debatForskningpeer review

145 Downloads (Pure)

Association of miR-548c-5p, miR-7-5p, miR-210-3p, miR-128-3p with recurrence in systemically untreated breast cancer

Block, I., Burton, M., Sørensen, K. P., Andersen, L., Larsen, M. J., Bak, M., Cold, S., Thomassen, M., Tan, Q. & Kruse, T. A., 6. feb. 2018, I : OncoTarget. 9, 10, s. 9030-9042

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

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Clinical and molecular characterization of BRCA-associated breast cancer: results from the DBCG

Soenderstrup, I. M. H., Laenkholm, A. V., Jensen, M. B., Eriksen, J. O., Gerdes, A. M., Hansen, T. V. O., Kruse, T. A., Larsen, M. J., Pedersen, I. S., Rossing, M., Thomassen, M. & Ejlertsen, B., jan. 2018, I : Acta Oncologica. 57, 1, s. 95-101

Publikation: Bidrag til tidsskriftKonferenceartikelForskningpeer review

Disease-Free Survival
Neoplasms
Mutation
Proportional Hazards Models
Paraffin
109 Downloads (Pure)

Differential effect of surgical manipulation on gene expression in normal breast tissue and breast tumor tissue

Pedersen, I. S., Thomassen, M., Tan, Q., Kruse, T. A., Thorlacius-Ussing, O., Garne, J. P. & Krarup, H. B., 16. nov. 2018, I : Molecular Medicine. 24, 8 s., 57.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

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Neoplasms
Gene Expression Profiling
Transcriptome
Freezing
137 Downloads (Pure)

Identification of metastasis driver genes by massive parallel sequencing of successive steps of breast cancer progression

Krøigård, A. B., Larsen, M. J., Lænkholm, A-V., Knoop, A. S., Jensen, J. D., Bak, M., Mollenhauer, J., Thomassen, M. & Kruse, T. A., 1. jan. 2018, I : PLOS ONE. 13, 1, 18 s., e0189887.

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metastasis
breast neoplasms
Genes
neoplasms
genes
59 Downloads (Pure)

Interim analysis of the Daliah trial - a randomized controlled phase iii clinical trial Comparing recombinant interferon alpha-2 vs. Hydroxyurea in MPN patients.

Knudsen, T. A., Lund Hansen, D., Ocias, L. F., Weiss Bjerrum, O., Brabrand, M., El Fassi, D., Frederiksen, M., Kjær, L., Kielsgaard Kristensen, T., Kruse, T. A., Mourits-Andersen, H. T., Møller, P., Overgaard, U. M., Severinsen, M. T., Skov, V. H., Stentoft, J., Starklint, J., de Stricker, K., Thomassen, M., Larsen, T. S. & 1 flere, Hasselbalch, H. C., 15. jun. 2018, I : HemaSphere. 2, S1, s. 18-19 S131.

Publikation: Bidrag til tidsskriftKonferenceabstrakt i tidsskriftForskningpeer review

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Molecular heterogeneity of mantle cell lymphoma

Cédile, O., Hansen, M. C., Ebbesen, L. H., Nørgaard Bentzen, H. H., Thomassen, M., Kruse, T. A., Kavan, S., Møller, M. B., Kielsgaard Kristensen, T., Christensen, J. H., Abildgaard, N. & Nyvold, C. G., 4. maj 2018.

Publikation: Konferencebidrag uden forlag/tidsskriftKonferenceabstrakt til konferenceForskningpeer review

171 Downloads (Pure)

Mutational Spectrum in a Worldwide Study of 29,700 Families with BRCA1 or BRCA2 Mutations

Rebbeck, T. R., Friebel, T. M., Friedman, E., Hamann, U., Huo, D., Kwong, A., Olah, E., Olopade, O. I., Solano, A. R., Teo, S-H., Thomassen, M., Weitzel, J. N., Chan, T. L., Couch, F. J., Goldgar, D. E., Kruse, T. A., Palmero, E. I., Park, S. K., Torres, D., van Rensburg, E. J. & 31 flere, McGuffog, L., Parsons, M. T., Leslie, G., Aalfs, C. M., Abugattas, J., Adlard, J., Agata, S., Aittomäki, K., Andrews, L., Andrulis, I. L., Arason, A., Arnold, N., Arun, B. K., Asseryanis, E., Auerbach, L., Azzollini, J., Balmaña, J., Barile, M., Barkardottir, R. B., Barrowdale, D., Benitez, J., Berger, A., Berger, R., Blanco, A. M., Blazer, K. R., Blok, M. J., Bonadona, V., Gerdes, A-M., Nielsen, H. R., Skytte, A-B. & EMBRACE, maj 2018, I : Human Mutation. 39, 5, s. 593-620

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

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Mutation
Population
Research Personnel
Germ-Line Mutation
Mutation Rate

Myeloproliferative Neoplasms in Danish Twins

Andersen, M. A., Bjerrum, O. W., Ranjan, A., Skov, V., Kruse, T. A., Thomassen, M., Skytthe, A., Hasselbalch, H. C. & Christensen, K., 3. maj 2018, I : Acta Haematologica. 139, 3, s. 195-198

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Neoplasms
Monozygotic Twins
Registries
Dizygotic Twins
Cell Lineage

NEW POTENTIAL CANDIDATE GENES IN MANTLE CELL LYMPHOMA

Cédile, O., Hansen, M. C., Ebbesen, L. H., Nørgaard Bentzen, H. H., Thomassen, M., Kruse, T. A., Kavan, S., Møller, M. B., Kielsgaard Kristensen, T., Christensen, J. H., Abildgaard, N. & Nyvold, C. G., 14. jun. 2018.

Publikation: Konferencebidrag uden forlag/tidsskriftKonferenceabstrakt til konferenceForskningpeer review

NEW POTENTIAL CANDIDATE GENES IN MANTLE CELL LYMPHOMA

Cédile, O., Hansen, M. C., Ebbesen, L. H., Nørgaard Bentzen, H. H., Thomassen, M., Kruse, T. A., Kavan, S., Møller, M. B., Kielsgaard Kristensen, T., Christensen, J. H., Abildgaard, N. & Nyvold, C. G., 14. jun. 2018, I : EHA Learning Center. 2018, PB2322.

Publikation: Bidrag til tidsskriftKonferenceabstrakt i tidsskriftForskningpeer review

63 Downloads (Pure)

Publisher Correction: Epigenetic changes in myelofibrosis: Distinct methylation changes in the myeloid compartments and in cases with ASXL1 mutations (Scientific Reports, (2017), 7, 1, (6774), 10.1038/s41598-017-07057-3)

Nielsen, H. M., Andersen, C. L., Westman, M., Kristensen, L. S., Asmar, F., Kruse, T. A., Thomassen, M., Larsen, T. S., Skov, V., Hansen, L. L., Bjerrum, O. W., Hasselbalch, H. C., Punj, V. & Grønbæk, K., 20. nov. 2018, I : Scientific Reports. 8, 1 s., 17311.

Publikation: Bidrag til tidsskriftKommentar/debatForskningpeer review

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Epigenomics
Mutation

SAFETY AND EFFICACY OF COMBINATION THERAPY OF INTERFERON ΑLPHA-2 AND RUXOLITINIB IN POLYCYTHEMIA VERA AND LOW-/INTERMEDIATE-1-RISK MYELOFIBROSIS – A ONE YEAR FOLLOW-UP UPDATE OF A PHASE II STUDY

Mikkelsen, S. U., Kjær, L., Bjørn, M. E., Knudsen, T. A., Sørensen, A. L., Skov, V., Andersen, C. B. L., Weiss Bjerrum, O., Brochmann Mortensen, N., El Fassi, D., Kruse, T. A., Larsen, T. S., Mourits-Andersen, H. T., Nielsen, C. H., Pallisgaard, N., Thomassen, M. & Hasselbalch, H. C., jun. 2018, I : EHA Learning Center. 2018, PF620.

Publikation: Bidrag til tidsskriftKonferenceabstrakt i tidsskriftForskningpeer review

150 Downloads (Pure)

Safety and efficacy of combination therapy of interferon-α2 and ruxolitinib in polycythemia vera and myelofibrosis

Mikkelsen, S. U., Kjær, L., Bjørn, M. E., Knudsen, T. A., Sørensen, A. L., Andersen, C. B. L., Bjerrum, O. W., Brochmann, N., Fassi, D. E., Kruse, T. A., Larsen, T. S., Mourits-Andersen, H. T., Nielsen, C. H., Pallisgaard, N., Thomassen, M., Skov, V. & Hasselbalch, H. C., 1. aug. 2018, I : Cancer Medicine. 7, 8, s. 3571-3581

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

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Polycythemia Vera
Safety
INCB018424
Neoplasms
Alleles

Sorted peripheral blood cells identify CALR mutations in B- and T-lymphocytes

Kjaer, L., Holmström, M. O., Cordua, S., Andersen, M. H., Svane, I. M., Thomassen, M., Kruse, T. A., Pallisgaard, N., Skov, V. & Hasselbalch, H. C., apr. 2018, I : Leukemia and Lymphoma. 59, 4, s. 973-977

Publikation: Bidrag til tidsskriftKommentar/debatFormidling

The BRCA1 c. 5096G>A p.Arg1699Gln (R1699Q) intermediate risk variant: breast and ovarian cancer risk estimation and recommendations for clinical management from the ENIGMA consortium

Moghadasi, S., Meeks, H. D., Vreeswijk, M. P., Janssen, L. A., Borg, Å., Ehrencrona, H., Paulsson-Karlsson, Y., Wappenschmidt, B., Engel, C., Gehrig, A., Arnold, N., Hansen, T. V. O., Thomassen, M., Jensen, U. B., Kruse, T. A., Ejlertsen, B., Gerdes, A-M., Pedersen, I. S., Caputo, S. M., Couch, F. & 20 flere, Hallberg, E. J., van den Ouweland, A. M., Collée, M. J., Teugels, E., Adank, M. A., van der Luijt, R. B., Mensenkamp, A. R., Oosterwijk, J. C., Blok, M. J., Janin, N., Claes, K. B., Tucker, K., Viassolo, V., Toland, A. E., Eccles, D. E., Devilee, P., Van Asperen, C. J., Spurdle, A. B., Goldgar, D. E. & Garcia, E. B. G., jan. 2018, I : Journal of Medical Genetics. 55, 1, s. 15-20

Publikation: Bidrag til tidsskriftLetterForskningpeer review

Ovarian Neoplasms
Alleles
Neoplasms
Ovariectomy
93 Downloads (Pure)

Whole Blood Gene Expression Profiling in patients undergoing colon cancer surgery identifies differential expression of genes involved in immune surveillance, inflammation and carcinogenesis

Watt, S. K., Hasselbalch, H. C., Skov, V., Kjær, L., Thomassen, M., Kruse, T. A., Burton, M. & Gögenur, I., jun. 2018, I : Surgical Oncology. 27, 2, s. 208-215

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Gene Expression Profiling
Colonic Neoplasms
Ambulatory Surgical Procedures
Down-Regulation
Chemical Databases
2017
193 Downloads (Pure)

Differential DNA methylation patterns of polycystic ovarian syndrome in whole blood of Chinese women

Li, S., Zhu, D., Duan, H., Ren, A., Glintborg, D., Andersen, M., Skov, V., Thomassen, M., Kruse, T. & Tan, Q., 1. jan. 2017, I : Oncotarget. 8, 13, s. 20656-20666

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Polycystic Ovary Syndrome
DNA Methylation
Epigenomics
Prolactin
DNA
150 Downloads (Pure)

Epigenetic changes in myelofibrosis: Distinct methylation changes in the myeloid compartments and in cases with ASXL1 mutations

Myrtue Nielsen, H., Lykkegaard Andersen, C., Westman, M., Sommer Kristensen, L., Asmar, F., Kruse, T. A., Thomassen, M., Stauffer Larsen, T., Skov, V., Lotte Hansen, L., Weis Bjerrum, O., Carl Hasselbalch, H., Punj, V. & Grønbæk, K., 1. dec. 2017, I : Scientific Reports. 7, 11 s., 6774.

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Epigenomics
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Histones
Nucleic Acid Regulatory Sequences
149 Downloads (Pure)
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Cluster Analysis
Health
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Genomic analyses of breast cancer progression reveal distinct routes of metastasis emergence

Krøigård, A. B., Larsen, M. J., Brasch-Andersen, C., Lænkholm, A. V., Knoop, A. S., Jensen, J. D., Bak, M., Mollenhauer, J., Thomassen, M. & Kruse, T. A., 2017, I : Scientific Reports. 7, 9 s., 43813.

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Neoplasms
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Identification, replication and characterization of epigenetic remodelling in the aging genome

Li, S., Christiansen, L., Christensen, K., Kruse, T. A., Redmond, P., Marioni, R. E., Deary, L. J. & Tan, Q., 2017. 1 s.

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Epigenomics
CpG Islands
DNA
DNA Methylation
120 Downloads (Pure)

Identification, replication and characterization of epigenetic remodelling in the aging genome: a cross population analysis

Li, S., Christiansen, L., Christensen, K., Kruse, T. A., Redmond, P., Marioni, R. E., Deary, I. J. & Tan, Q., 15. aug. 2017, I : Scientific Reports. 7, 1, 8 s., 8183.

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Epigenomics
CpG Islands
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119 Downloads (Pure)

Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer

Phelan, C. M., Kuchenbaecker, K. B., Tyrer, J. P., Kar, S. P., Lawrenson, K., Winham, S. J., Dennis, J., Pirie, A., Riggan, M. J., Chornokur, G., Earp, M. A., Lyra, P. C., Lee, J. M., Coetzee, S., Beesley, J., McGuffog, L., Soucy, P., Dicks, E., Lee, A., Barrowdale, D. & 31 flere, Lecarpentier, J., Leslie, G., Aalfs, C. M., Aben, K. K. H., Adams, M., Adlard, J., Andrulis, I. L., Anton-Culver, H., Antonenkova, N. N., Aravantinos, G., Arnold, N., Arun, B. K., Arver, B., Azzollini, J., Balmaña, J., Banerjee, S. N., Barjhoux, L., Barkardottir, R. B., Bean, Y., Beckmann, M. W., Beeghly-Fadiel, A., Benitez, J., Bermisheva, M., Bernardini, M. Q., Birrer, M. J., Bjorge, L., Bojesen, A., Gerdes, A-M., Kruse, T. A., Thomassen, M. & AOCS study group, 2017, I : Nature Genetics. 49, 5, s. 680-691

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Mutation
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126 Downloads (Pure)

Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer

Milne, R. L., Kuchenbaecker, K. B., Michailidou, K., Beesley, J., Kar, S., Lindström, S., Hui, S., Lemaçon, A., Soucy, P., Dennis, J., Jiang, X., Rostamianfar, A., Finucane, H., Bolla, M. K., McGuffog, L., Wang, Q., Aalfs, C. M., Adams, M., Adlard, J., Agata, S. & 31 flere, Ahmed, S., Ahsan, H., Aittomäki, K., Al-Ejeh, F., Allen, J., Ambrosone, C. B., Amos, C. I., Andrulis, I. L., Anton-Culver, H., Antonenkova, N. N., Arndt, V., Arnold, N., Aronson, K. J., Auber, B., Auer, P. L., Ausems, M. G. E. M., Azzollini, J., Bacot, F., Balmaña, J., Barile, M., Barjhoux, L., Barkardottir, R. B., Barrdahl, M., Barnes, D., Barrowdale, D., Bojesen, A., Gerdes, A-M., Kruse, T. A., Lænkholm, A-V., Thomassen, M. & ABCTB Investigators, 1. dec. 2017, I : Nature Genetics. 49, 12, s. 1767–1778

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Genome-Wide Association Study
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Investigating a case of possible field cancerization in oral squamous cell carcinoma by the use of next-generation sequencing

Tabatabaeifar, S., Larsen, M. J., Larsen, S. R., Kruse, T. A., Thomassen, M. & Sørensen, J. A., 2017, I : Oral Oncology. 68, s. 74-80

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Mutation
Neoplasms
Oral Stage
Exome
Paraffin
105 Downloads (Pure)

Mathematical modelling as a proof of concept for MPNs as a human inflammation model for cancer development

Andersen, M., Sajid, Z., Pedersen, R. K., Gudmand-Hoeyer, J., Ellervik, C., Skov, V., Kjær, L., Pallisgaard, N., Kruse, T. A., Thomassen, M., Troelsen, J., Hasselbalch, H. C. & Ottesen, J. T., 2017, I : PLOS ONE. 12, 8, 18 s., e0183620.

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Stem cells
mathematical models
inflammation
neoplasms
Feedback
172 Downloads (Pure)

Prediction of Breast and Prostate Cancer Risks in Male BRCA1 and BRCA2 Mutation Carriers Using Polygenic Risk Scores

Lecarpentier, J., Silvestri, V., Kuchenbaecker, K. B., Barrowdale, D., Dennis, J., McGuffog, L., Soucy, P., Leslie, G., Rizzolo, P., Navazio, A. S., Valentini, V., Zelli, V., Lee, A., Amin Al Olama, A., Tyrer, J. P., Southey, M., John, E. M., Conner, T. A., Goldgar, D. E., Buys, S. & 31 flere, Janavicius, R., Steele, L., Ding, Y. C., Neuhausen, S. L., Hansen, T. V. O., Osorio, A., Weitzel, J. N., Toss, A., Medici, V., Cortesi, L., Zanna, I., Palli, D., Radice, P., Manoukian, S., Peissel, B., Azzollini, J., Viel, A., Cini, G., Damante, G., Tommasi, S., Peterlongo, P., Fostira, F., Hamann, U., Evans, D. G., Bojesen, A., Nielsen, H. R., Skytte, A-B., Krogh, L., Kruse, T. A., Thomassen, M. & EMBRACE, 10. jul. 2017, I : Journal of Clinical Oncology. 35, 20, s. 2240-2250

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Prostatic Neoplasms
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Odds Ratio
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The gene expression and immunohistochemical time-course of diphenylcyclopropenone induced contact allergy in healthy humans following repeated epicutaneous challenges

Mose, K. F., Burton, M., Thomassen, M., Andersen, F., Kruse, T. A., Tan, Q., Skov, L., Almose Røpke, M., Litman, T., Clemmensen, O., Kristensen, B. W., S. Friedmann, P. & Andersen, K. E., 2017, I : Experimental Dermatology. 26, 10, s. 926–933

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Hypersensitivity
diphenylcyclopropenone
Polymerase Chain Reaction
Interleukin-17
Gene Expression Profiling

The impact of interferon-alpha2 on HLA genes in patients with polycythemia vera and related neoplasms

Skov, V., Riley, C. H., Thomassen, M., Kjær, L., Stauffer Larsen, T., Bjerrum, O. W., Kruse, T. A. & Hasselbalch, H. C., aug. 2017, I : Leukemia and Lymphoma. 58, 8, s. 1914-1921

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Polycythemia Vera
Neoplasms
Up-Regulation
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Clonal Evolution
227 Downloads (Pure)

The subclonal structure and genomic evolution of oral squamous cell carcinoma revealed by ultra-deep sequencing

Tabatabaeifar, S., Thomassen, M., Larsen, M. J., Larsen, S. R., Kruse, T. A. & Sørensen, J. A., 2017, I : OncoTarget. 8, 10, s. 16571-16580

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Neoplasms
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