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2011
Wnt Signaling Pathway
MAP Kinase Signaling System
Stem cells
Mesenchymal Stromal Cells
Bone

Bone regeneration and stem cells

Arvidson, K., Abdallah, B. M., Applegate, L. A., Baldini, N., Cenni, E., Gomez-Barrena, E., Granchi, D., Kassem, M., Konttinen, Y. T., Mustafa, K. A., Pioletti, D. P., Sillat, T. & Finne-Wistrand, A., 2011, I : Journal of Cellular and Molecular Medicine. 15, 4, s. 718-746

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Mesenchymal Stromal Cells
Fetal Stem Cells
Fracture Healing
Platelet-Rich Plasma
Tissue Engineering

Cancer stem cell overexpression of nicotinamide N-methyltransferase enhances cellular radiation resistance

D'Andrea, F. P., Safwat, A., Kassem, M., Gautier, L., Overgaard, J. & Horsman, M. R., 1. jun. 2011, I : Radiotherapy & Oncology. 99, 3, s. 373-8 6 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Mesenchymal Stromal Cells
Seeds
Clone Cells
Population

CD146 expression on primary nonhematopoietic bone marrow stem cells is correlated with in situ localization

Tormin, A., Li, O., Brune, J. C., Walsh, S., Schütz, B., Ehinger, M., Ditzel, N., Kassem, M. & Scheding, S., 2011, I : Blood. 117, 19, s. 5067-77 11 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Mesenchymal Stromal Cells
Population
Stromal Cells
Cultured Cells
Fibroblasts

Cell shape and spreading of stromal (mesenchymal) stem cells cultured on fibronectin coated gold and hydroxyapatite surfaces

Dolatshahi-Pirouz, A., Jensen, T. H. L., Kolind, K., Bünger, C., Kassem, M., Foss, M. & Besenbacher, F., 2011, I : Colloids and Surfaces B: Biointerfaces. 84, 1, s. 18-25 8 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Cell Shape
stem cells
Durapatite
Stem cells
Mesenchymal Stromal Cells

Circulating osteogenic cells: implications for injury, repair, and regeneration

Pignolo, R. J. & Kassem, M., 2011, I : Journal of Bone and Mineral Research. 26, 8, s. 1685-93 9 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Wounds and Injuries
Osteogenesis
Reading

CXCR4 expression in human mesenchymal stem cells enhances in vitro migration

Andersen, R. K., Clausen, C., Jørgensen, F., Holst, B., Zaher, W. & Kassem, M., 2011.

Publikation: Konferencebidrag uden forlag/tidsskriftPosterForskning

Decellularized matrix from tumorigenic human mesenchymal stem cells promotes neovascularization with galectin-1 dependent endothelial interaction

Burns, J. S., Kristiansen, M., Kristensen, L. P., Larsen, K. H., Nielsen, M. O., Christiansen, H., Nehlin, J., Andersen, J. S. & Kassem, M., 1. jan. 2011, I : P L o S One. 6, 7, s. e21888

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Galectin 1
angiogenesis
Stem cells
Mesenchymal Stromal Cells
stem cells

Delta-like 1/fetal antigen-1 (Dlk1/FA1) is a novel regulator of chondrogenic cell differentiation via inhibition of the Akt kinase-dependent pathway

Chen, L., Qanie, D., Jafari, A., Taipaleenmaki, H., Jensen, C. H., Säämänen, A-M., Sanz, M. L. N., Laborda, J., Abdallah, B. M. & Kassem, M., 2011, I : Journal of Biological Chemistry. 286, 37, s. 32140-9 10 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Cell Differentiation
Phosphotransferases
Antigens
Chondrogenesis
Fibronectins

Development of novel monoclonal antibodies that define differentiation stages of human stromal (mesenchymal) stem cells

Andersen, D. C., Kortesidis, A., Zannettino, A. C. W., Kratchmarova, I., Chen, L., Jensen, O. N., Teisner, B., Gronthos, S., Jensen, C. H. & Kassem, M., 2011, I : Molecules and Cells. 32, 2, s. 133-142 10 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Mesenchymal Stromal Cells
HLA-DRB1 Chains
Alkaline Phosphatase
Flow Cytometry
Membrane Proteins

Direct differentiation of human embryonic stem cells toward osteoblasts and chondrocytes through an intermediate mesenchyme progenitor lineage.

Abdallah, B., Harkness, L., Mahmood, A. & Kassem, M., 2011, Embryonic Stem Cells: The Hormonal Regulation of Pluripotency and Embryogenesis. Atwood, C. (red.). InTech - Open Access Publisher, s. 607-620

Publikation: Bidrag til bog/antologi/rapport/konference-proceedingBidrag til bog/antologiForskningpeer review

DLK1 is a novel regulator of bone mass that mediates estrogen deficiency-induced bone loss in mice

Abdallah, B. M., Ditzel, N., Mahmood, A., Isa, A., Traustadottir, G. A., Schilling, A. F., Ruiz-Hidalgo, M-J., Laborda, J., Amling, M. & Kassem, M., 2011, I : Journal of Bone and Mineral Research. 26, 7, s. 1457-71 15 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Estrogens
Osteogenesis
Osteoblasts
Postmenopausal Osteoporosis
Ovariectomy

En Kur mod Alzheimers sygdom

Kassem, M., 2011, I : Sund i syd. 1, 5, s. 6-7 2 s.

Publikation: Bidrag til tidsskriftBidrag til avis - AvisartikelFormidling

Estrogen inhibits Dlk1/FA1 production: A potential mechanism for estrogen effects on bone turnover

Abdallah, B. M., Bay-Jensen, A-C., Srinivasan, B., Tabassi, N. C., Garnero, P., Delaissé, J-M., Khosla, S. & Kassem, M., 2011, I : Journal of Bone and Mineral Research. 26, 10, s. 2548-2551

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Estrogens
Estrogen Replacement Therapy
Osteocalcin
Serum

Extrinsic Mechanisms Involved in Age-Related Defective Bone Formation

Trinquier, A. M-P. E. & Kassem, M., 2011, I : Journal of Clinical Endocrinology and Metabolism. 96, 3, s. 600-609 10 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Osteogenesis
Osteoblasts
PubMed
Rodentia
Population

Flow perfusion culture of human mesenchymal stem cells on coralline hydroxyapatite scaffolds with various pore sizes

Bjerre, L., Bünger, C., Baatrup, A., Kassem, M. & Mygind, T., 2011, I : Journal of Biomedical Materials Research. Part A. 97A, 3, s. 251-63 13 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Stem cells
Hydroxyapatite
Cell culture
Scaffolds
Pore size

HLA-B expression during diffenrentiation from embryonic stem cells to lymphocytes, adipocytes and osteocytes

Sabir, H. J., Isa, A., Nehlin, J., Qanie, D. W. M., Harkness, L., Prokhorova, T., Kassem, M. & Barington, T., 21. sep. 2011.

Publikation: Konferencebidrag uden forlag/tidsskriftPosterForskning

Human Serum is as Efficient as Fetal Bovine Serum in Supporting Proliferation and Differentiation of Human Multipotent Stromal (Mesenchymal) Stem Cells In Vitro and In Vivo

Aldahmash, A., Haack-Sørensen, M., Al-Nbaheen, M., Harkness, L., Abdallah, B. M. & Kassem, M., 2011, I : Stem Cell Reviews. 7, 4, s. 860-868

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Mesenchymal Stromal Cells
Serum
In Vitro Techniques
Lipoprotein Lipase
Telomerase

Levels of serotonin, sclerostin, bone turnover markers as well as bone density and microarchitecture in patients with high bone mass phenotype due to a mutation in Lrp5

Nielsen, M. F., Andersen, T. E., Gossiel, F., Hansen, S., Bollerslev, J., Van Hul, W., Eastell, R., Kassem, M. & Brixen, K., 2011, I : Journal of Bone and Mineral Research. 26, 8, s. 1721-1728 8 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Bone Density
Mutation
Forearm
Serum
Hip

MicroRNA-138 regulates osteogenic differentiation of human stromal (mesenchymal) stem cells in vivo

Eskildsen, T., Taipaleenmäki, H., Stenvang, J., Abdallah, B. M., Ditzel, N., Nossent, A. Y., Bak, M., Kauppinen, S. & Kassem, M., 2011, I : Proceedings of the National Academy of Sciences of the United States of America. 108, 15, s. 6139-44 6 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

MicroRNAs
Mesenchymal Stromal Cells
Osteoblasts
Osteogenesis
Luciferases

New factors controlling the balance between osteoblastogenesis and adipogenesis

Abdallah, B. M. & Kassem, M., 2011, I : Bone. 50, 2, s. 540-5 6 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Adipogenesis
Adiposity
Osteoblasts
Adipocytes
Population

Osteoblasts in osteoporosis: past, emerging, and future anabolic targets

Marie, P. J. & Kassem, M., 2011, I : European Journal of Endocrinology. 165, 1, s. 1-10 10 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Osteoblasts
Osteogenesis
Pharmaceutical Preparations

PDX1- and NGN3-mediated in vitro reprogramming of human bone marrow-derived mesenchymal stromal cells into pancreatic endocrine lineages

Limbert, C., Päth, G., Ebert, R., Rothhammer, V., Kassem, M., Jakob, F. & Seufert, J., 2011, I : Cytotherapy. 13, 7, s. 802-13 12 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Mesenchymal Stromal Cells
In Vitro Techniques

Selective isolation and differentiation of a stromal population of human embryonic stem cells with osteogenic potential

Harkness, L. M., Mahmood, A., Ditzel, N., Abdallah, B. M., Nygaard, J. V. & Kassem, M., 2011, I : Bone. 48, 1, s. 231-241

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Population
Stromal Cells
Fibroblasts
Cell Line
Regenerative Medicine

Self-assembled composite matrix in a hierarchical 3D scaffold for bone tissue engineering

Chen, M., Le, D. Q. S., Baatrup, A., Nygaard, J. V., Hein, S., Bjerre, L., Kassem, M., Zou, X. & Bünger, C., 2011, I : Acta Biomaterialia. 7, 5, s. 2244-2255 12 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Polycaprolactone
Tissue Engineering
Scaffolds (biology)
Tissue engineering
Scaffolds

Senescence-associated intrinsic mechanisms of osteoblast dysfunctions

Kassem, M. & Trinquier, A. M-P. E., 2011, I : Aging Cell. 10, 2, s. 191-7 7 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Osteoblasts
Cell Aging
Skeleton
Hormones

Separate developmental programs for HLA-A and -B expression during diffenrentiation from embryonic stem cells to lymphocytes, adipocytes and osteocytes

Sabir, H. J., Isa, A., Nehlin, J., Qanie, D. W. M., M, L., Prokhorova, T., Kassem, M. & Barington, T., 28. apr. 2011.

Publikation: Konferencebidrag uden forlag/tidsskriftPosterForskning

Snorc is a novel cartilage specific small membrane proteoglycan expressed in differentiating and articular chondrocytes

Heinonen, J., Taipaleenmäki, H., Roering, P., Takatalo, M., Harkness, L., Sandholm, J., Uusitalo-Järvinen, H., Kassem, M., Kiviranta, I., Laitala-Leinonen, T. & Säämänen, A-M., 2011, I : Osteoarthritis and Cartilage. 19, 8, s. 1026-35 10 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Cartilage
Chondrocytes
Joints
Membranes
Chondrogenesis

System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation

Rigbolt, K. T. G., Prokhorova, T. A., Akimov, V., Henningsen, J., Johansen, P. T., Kratchmarova, I., Kassem, M., Mann, M., Olsen, J. V. & Blagoev, B., 2011, I : Science Signaling. 4, 164, s. rs3

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Phosphorylation
Proteome
Stem cells
Cell Differentiation
Methyltransferases

Telomerase-Deficient Mice Exhibit Bone Loss Owing to Defects in Osteoblasts and Increased Osteoclastogenesis by Inflammatory Microenvironment

Saeed, H., Abdallah, B. M., Ditzel, N., Catala-Lehnen, P., Qiu, W. M., Amling, M. & Kassem, M., 2011, I : Journal of Bone and Mineral Research. 26, 7, s. 1494-1505 12 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

TGFb signalling inhibits DLK1 expression during chondrogenesis in vitro

Harkness, L., Taipaleenmaki, H., Saamanen, A-M., Kassem, M. & Abdallah, B., 15. jun. 2011.

Publikation: Konferencebidrag uden forlag/tidsskriftPosterForskning

Chondrogenesis
Chondrocytes
Fibroblasts
Limb Buds
Cell Lineage

The best bone marrow stromal cell for therapy is … 'yellow'

Burns, J. S. & Kassem, M., 2011, I : Cytotherapy. 13, 6, s. 644-6 3 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Tumourigenicity and radiation resistance of mesenchymal stem cells

D'Andrea, F. P., Horsman, M. R., Kassem, M., Overgaard, J. & Safwat, A., 2011, I : Acta Oncologica. 51, 5, s. 669-79 11 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Mesenchymal Stromal Cells
Cell Line
Chromosome Mapping
Connective Tissue
Neoplasms

Wnt signalling mediates the cross-talk between bone marrow derived pre-adipocytic and pre-osteoblastic cell populations

Taipaleenmaki, H., Abdallah, B. M., Aldamash, A., Säämänen, A-M. & Kassem, M., 2011, I : Experimental Cell Research. 317, 6, s. 745-56 12 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Population
Chondrocytes
Osteoblasts
Mesenchymal Stromal Cells
Lipid Metabolism
2012

Bioactive implants: RNA interference as a tool to direct stem cell differentiation.

Dillschneider, P., Andersen, M. Ø., Kjems, J. & Kassem, M., 2012, I : Journal of Tissue Engineering and Regenerative Medicine. 6, S1, s. 292 1 s., 49.P05.

Publikation: Bidrag til tidsskriftKonferenceabstrakt i tidsskriftForskningpeer review

Controlling drug release spatially and temporally in scaffolds

Andersen, M. Ø., Nygaard, J. V., Le, D. Q. S., Burns, J., Raarup, M. K., Chen, M., Howard, K. A., Bünger, C., Kassem, M. & Kjems, J., 2012, I : Journal of Tissue Engineering and Regenerative Medicine. 6, S1

Publikation: Bidrag til tidsskriftKonferenceabstrakt i tidsskriftForskningpeer review

Derivation of Stromal (Skeletal, Mesenchymal) Stem-like cells from Human Embryonic Stem Cells

Mahmood, A., Harkness, L., Abdallah, B., El-Safadi, M., Al-Nbheen, M., Aldahmash, A. & Kassem, M., 2012, I : Stem Cells and Development. 21, 17, s. 3114-3124

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Mesenchymal Stromal Cells
Durapatite
Osteoblasts
Tissue Engineering
Human Embryonic Stem Cells

Encapsulated glucagon-like peptide-1-producing mesenchymal stem cells have a beneficial effect on failing pig hearts

Wright, E. J., Farrell, K. A., Malik, N., Kassem, M., Lewis, A. L., Wallrapp, C. & Holt, C. M., 2012, I : Stem Cells Translational Medicine. 1, 10, s. 759-69 11 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Mesenchymal Stromal Cells
Stem Cell Factor
Left Ventricular Function
Stromal Cells
Infarction

Fabrication and characterization of a rapid prototyped tissue engineering scaffold with embedded multicomponent matrix for controlled drug release

Chen, M., Le, D. Q., Hein, S., Li, P., Nygaard, J. V., Kassem, M., Kjems, J., Besenbacher, F. & Bünger, C., 2012, I : International Journal of Nanomedicine (Online). 7, s. 4285-97 13 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Tissue Scaffolds
Tissue Engineering
Scaffolds (biology)
Tissue engineering
Scaffolds

Glucose metabolite glyoxal induces senescence in telomerase-immortalized human mesenchymal stem cells

Larsen, S. A., Kassem, M. & Rattan, S. I., 2012, I : Chemistry Central Journal. 6, 1, s. 18

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Glyoxal
Telomerase
Metabolites
Stem cells
Glucose

Human stromal (mesenchymal) stem cells: basic biology and current clinical use for tissue regeneration

Aldahmash, A., Zaher, W., Al-Nbaheen, M. & Kassem, M., 2012, I : Annals of Saudi Medicine. 32, 1, s. 68-77 10 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Mesenchymal Stromal Cells
Cell Biology
Subcutaneous Fat
Bone Fractures
Mesoderm

Identification of Abnormal Stem Cells Using Raman Spectroscopy

Harkness, L., Novikov, S. M., Beermann, J., Bozhevolnyi, S. I. & Kassem, M., 2012, I : Stem Cells and Development. 21, 12, s. 2152-9 9 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Microscopy
Stromal Cells
Human Embryonic Stem Cells

Identification of a Predictive Molecular Signature For Ex Vivo Migration of Human Mesenchymal Stromal Cells

Andersen, R. K., Zaher, W., Larsen, K. H., Kassem, M. & Abdallah, B., 2012.

Publikation: Konferencebidrag uden forlag/tidsskriftKonferenceabstrakt til konferenceForskning

MECHANISMS IN ENDOCRINOLOGY MicroRNAs: Targets for enhancing osteoblast differentiation and bone formation

Taipaleenmäki, H., Bjerre, L., Chen, L., Kauppinen, S. & Kassem, M., 2012, I : European Journal of Endocrinology. 166, 3, s. 359-71 22 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Osteoblasts
MicroRNAs
Osteogenesis
Apoptosis

Mesenchymal Stem Cells: Application for Immunomodulation and Tissue Repair

Horwood, N. J., Dazzi, F., Zaher, W. & Kassem, M., 2012, Tissue and Cell Clinical Use: An Essential Guide . Warwick, R. M. & Brubaker, S. A. (red.). Wiley-Blackwell, s. 332-357

Publikation: Bidrag til bog/antologi/rapport/konference-proceedingBidrag til bog/antologiForskningpeer review

Mesenchymal Stromal Cells
Graft vs Host Disease
Mesoderm
Stromal Cells
Chondrocytes

Microcarrier-based expansion process for hMSCs with high vitality and undifferentiated characteristics

Elseberg, C. L., Leber, J., Salzig, D., Wallrapp, C., Kassem, M., Kraume, M. & Czermak, P., 2012, I : International Journal of Artificial Organs. 35, 2, s. 93-107 15 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Stem cells
Mesenchymal Stromal Cells
Glucose
Carrier concentration
Biomass

Mouse Embryonic Fibroblasts (MEF) Exhibit a Similar but not Identical Phenotype to Bone Marrow Stromal Stem Cells (BMSC)

Saeed, H., Taipaleenmäki, H., Aldahmash, A. M., Abdallah, B. M. & Kassem, M., 2012, I : Stem Cell Reviews. 8, 2, s. 318-28 11 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Mesenchymal Stromal Cells
Fibroblasts
Chondrocytes
Osteoblasts
Adipocytes

Procedures for Derivation and Characterisation of Human Embryonic Stem Cells from Odense, Denmark

Harkness, L. & Kassem, M., 2012, Human Embryonic Stem Cells Handbook: Methods in Molecular Biology. Turksen, K. (red.). Springer Science+Business Media, s. 33-51 (Methods in Molecular Medicine, Bind 873).

Publikation: Bidrag til bog/antologi/rapport/konference-proceedingBidrag til bog/antologiForskning

Denmark
Cell Line
Cell Biology
Flow Cytometry
Polymerase Chain Reaction

Sarcomas as a mise en abyme of mesenchymal stem cells: Exploiting interrelationships for cell mediated anticancer therapy

Burns, J. S., Safwat, A. A., Grisendi, G., Kassem, M. & Dominici, M., 2012, I : Cancer Letters. 325, 1, s. 1-10 10 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Mesenchymal Stromal Cells
Entosis
Sarcoma
Cell Fusion
Growth

Separate developmental programs for HLA-A and -B expression during diffenrentiation from embryonic stem cells to lymphocytes, adipocytes and osteocytes

Sabir, H. J., Isa, A., Nehlin, J., Qanie, D. W. M., Prokhorova, T., Kassem, M. & Barington, T., 31. maj 2012.

Publikation: Konferencebidrag uden forlag/tidsskriftKonferenceabstrakt til konferenceForskningpeer review