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2010

A small scale cell culture system to analyze mechanobiology using reporter gene constructs and polyurethane dishes

Seefried, L., Mueller-Deubert, S., Wentzer, T. S., Lind, T., Mentrup, B., Kober, M., Docheva, D., Liedert, A., Kassem, M., Ignatius, A., Schieker, M., Claes, L., Wilke, W., Jakob, F. & Ebert, R., 1. jan. 2010, I : European Cells & Materials. 20, s. 344-55 12 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Polyurethanes
Bioreactors
Reporter Genes
Cell culture
Signal transduction

Changes in left ventricular filling patterns after repeated injection of autologous bone marrow cells in heart failure patients

Diederichsen, A. C. P., Møller, J. E., Thayssen, P., Videbæk, L., Sækmose, S. G., Barington, T. & Kassem, M., 17. mar. 2010, I : Scandinavian Cardiovascular Journal. 44, 3, s. 139-145

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Plasma Volume
Brain Natriuretic Peptide
Outcome Assessment (Health Care)

Characterization of programmed death ligands in immune modulation of mesenchymal stem cells

Isa, A., Sabir, H. J., Nehlin, J., Andersen, T. E., Kassem, M. & Barington, T., 25. maj 2010.

Publikation: Konferencebidrag uden forlag/tidsskriftPosterForskning

Derivation and characterisation of hESC lines from supernumerary embryos, experience from Odense, Denmark

Harkness, L., Rasmussen, I. A., Erb, K. & Kassem, M., 2010, I : In Vitro Cellular & Developmental Biology - Animal. 46, 3-4, s. 259-268

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Denmark
Embryonic Structures
Cell Line
Polymerase Chain Reaction
Human Embryonic Stem Cells

Enhanced differentiation of human embryonic stem cells to mesenchymal progenitors by inhibition of TGF-beta/Activin/Nodal signaling using SB-431542

Mahmood, A., Harkness, L., Schrøder, H. D., Abdallah, B. & Kassem, M., 29. jan. 2010, I : Journal of Bone and Mineral Research. 25, 6, s. 1216-1223

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Inhibin-beta Subunits
Mesenchymal Stromal Cells
Up-Regulation
Regenerative Medicine
Desmin

Fibroblast growth factor 23 - et fosfatregulerende hormon

Beck-Nielsen, S., Pedersen, S. M., Kassem, M. & Rasmussen, L. M., 1. maj 2010, I : Ugeskrift for læger. 172, 20, s. 1521-1527 7 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Hormones
Hypophosphatemia
Serum
Reference Values

Human mesenchymal stem cells: Basic bone biology and clinical applications for bone tissue regeneration

Kassem, M., Al-Nbaheen, M., Ali, D. & Al-Dahmash, A., 2010, Stem Cells: From Bench to Bedside. Bongso, A. & Lee, E. H. (red.). 2 udg. World Scientific, s. 457-476 20 s.

Publikation: Bidrag til bog/antologi/rapport/konference-proceedingBidrag til bog/antologiForskningpeer review

Identification of target genes for wild type and truncated HMGA2 in mesenchymal stem-like cells

Henriksen, J. M., Stabell, M., Meza-Zepeda, L. A., Lauvrak, S. A., Kassem, M. & Myklebost, O., 1. jan. 2010, I : B M C Cancer. 10, s. 329

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Mesenchymal Stromal Cells
Neoplasms
Proteins

Impaired cell surface expression of HLA-B antigens on mesenchymal stem cells and muscle cell progenitors

Isa, A., Nehlin, J., Sabir, H. J., Andersen, T., Gaster, M., Kassem, M. & Barington, T., 2010, I : P L o S One. 5, 5, s. e10900

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

HLA-A Antigens
HLA-B Antigens
Stem cells
Mesenchymal Stromal Cells
myocytes

Interaction of human mesenchymal stem cells with osteopontin coated hydroxyapatite surfaces

Jensen, T., Dolatshahi-Pirouz, A., Foss, M., Baas, J., Lovmand, J., Duch, M., Pedersen, F. S., Kassem, M., Bünger, C., Søballe, K. & Besenbacher, F., 1. jan. 2010, I : Colloids and Surfaces B: Biointerfaces. 75, 1, s. 186-93 7 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Osteopontin
stem cells
Durapatite
Stem cells
Mesenchymal Stromal Cells

MAPKs are essential upstream signaling pathways in proteolytic cartilage degradation--divergence in pathways leading to aggrecanase and MMP-mediated articular cartilage degradation

Sondergaard, B-C., Schultz, N., Madsen, S. H., Bay-Jensen, A-C., Kassem, M. & Karsdal, M. A., 1. mar. 2010, I : Osteoarthritis and Cartilage. 18, 3, s. 279-88 10 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Cartilage
Matrix Metalloproteinases
Degradation
Chemical activation
Metalloproteases

Mechanosensitivity of dental pulp stem cells is related to their osteogenic maturity

Kraft, D. C. E., Bindslev, D. A., Melsen, B., Abdallah, B., Kassem, M. & Klein-Nulend, J., 1. feb. 2010, I : European Journal of Oral Sciences. 118, 1, s. 29-38 9 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Dental Pulp
Mesenchymal Stromal Cells
Pulsatile Flow
Osteogenesis
Osteocalcin
Stem cells
Mesenchymal Stromal Cells
Scaffolds
Bone
Collagen

Patients with high-bone-mass phenotype owing to Lrp5-T253I mutation have low plasma levels of serotonin

Frost, M., Andersen, T. E., Yadav, V., Brixen, K., Karsenty, G. & Kassem, M., 29. jan. 2010, I : Journal of Bone and Mineral Research. 25, 3, s. 673-675 2 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Mutation
Osteogenesis

Raman microscopy of individual living human embryonic stem cells

Novikov, S. M., Beermann, J., Bozhevolnyi, S. I., Harkness, L. & Kassem, M., 2010, I : Proceedings of SPIE. 7715, 771537.

Publikation: Bidrag til tidsskriftKonferenceartikelForskningpeer review

Stem cells
Microscopic examination
Glass
Biomolecules
Substrates

Reparation af knogle og brusk med stamceller

Larsen, K. H., Andersen, T. E. & Kassem, M., 20. sep. 2010, I : Ugeskrift for Laeger. 172, 38, s. 2616-9 4 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Mesenchymal Stromal Cells
Regenerative Medicine
Tissue Engineering
Chondrocytes
Osteoblasts

siRNA nanoparticle functionalization of nanostructured scaffolds enables controlled multilineage differentiation of stem cells

Andersen, M. Ø., Nygaard, J. V., Burns, J. S., Raarup, M. K., Nyengaard, J. R., Bünger, C., Besenbacher, F., Howard, K. A., Kassem, M. & Kjems, J., 1. nov. 2010, I : Molecular Therapy. 18, 11, s. 2018-27

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Small Interfering RNA
Tissue Engineering
Mesenchymal Stromal Cells
Morphogenesis
RNA

Stemceller

Pørneki, A. D. S. & Kassem, M., 2010, I : Cardiologisk Forum. 15, 4, s. 21-23 2 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelFormidling

Tumor necrosis factor receptor superfamily member 19 (TNFRSF19) regulates differentiation fate of human mesenchymal stem cell through canonical Wnt signaling and C/EBP

Qiu, W., Hu, Y., Andersen, T. E., Jafari Kermani, A., Li, N., Chen, W. & Kassem, M., 2010, I : Journal of Biological Chemistry. 285, s. 14438-14449

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

2012

Bioactive implants: RNA interference as a tool to direct stem cell differentiation.

Dillschneider, P., Andersen, M. Ø., Kjems, J. & Kassem, M., 2012, I : Journal of Tissue Engineering and Regenerative Medicine. 6, S1, s. 292 1 s., 49.P05.

Publikation: Bidrag til tidsskriftKonferenceabstrakt i tidsskriftForskningpeer review

Controlling drug release spatially and temporally in scaffolds

Andersen, M. Ø., Nygaard, J. V., Le, D. Q. S., Burns, J., Raarup, M. K., Chen, M., Howard, K. A., Bünger, C., Kassem, M. & Kjems, J., 2012, I : Journal of Tissue Engineering and Regenerative Medicine. 6, S1

Publikation: Bidrag til tidsskriftKonferenceabstrakt i tidsskriftForskningpeer review

Derivation of Stromal (Skeletal, Mesenchymal) Stem-like cells from Human Embryonic Stem Cells

Mahmood, A., Harkness, L., Abdallah, B., El-Safadi, M., Al-Nbheen, M., Aldahmash, A. & Kassem, M., 2012, I : Stem Cells and Development. 21, 17, s. 3114-3124

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Mesenchymal Stromal Cells
Durapatite
Osteoblasts
Tissue Engineering
Human Embryonic Stem Cells

Encapsulated glucagon-like peptide-1-producing mesenchymal stem cells have a beneficial effect on failing pig hearts

Wright, E. J., Farrell, K. A., Malik, N., Kassem, M., Lewis, A. L., Wallrapp, C. & Holt, C. M., 2012, I : Stem Cells Translational Medicine. 1, 10, s. 759-69 11 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Mesenchymal Stromal Cells
Stem Cell Factor
Left Ventricular Function
Stromal Cells
Infarction

Fabrication and characterization of a rapid prototyped tissue engineering scaffold with embedded multicomponent matrix for controlled drug release

Chen, M., Le, D. Q., Hein, S., Li, P., Nygaard, J. V., Kassem, M., Kjems, J., Besenbacher, F. & Bünger, C., 2012, I : International Journal of Nanomedicine (Online). 7, s. 4285-97 13 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Tissue Scaffolds
Tissue Engineering
Scaffolds (biology)
Tissue engineering
Scaffolds

Glucose metabolite glyoxal induces senescence in telomerase-immortalized human mesenchymal stem cells

Larsen, S. A., Kassem, M. & Rattan, S. I., 2012, I : Chemistry Central Journal. 6, 1, s. 18

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Glyoxal
Telomerase
Metabolites
Stem cells
Glucose

Human stromal (mesenchymal) stem cells: basic biology and current clinical use for tissue regeneration

Aldahmash, A., Zaher, W., Al-Nbaheen, M. & Kassem, M., 2012, I : Annals of Saudi Medicine. 32, 1, s. 68-77 10 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Mesenchymal Stromal Cells
Cell Biology
Subcutaneous Fat
Bone Fractures
Mesoderm

Identification of Abnormal Stem Cells Using Raman Spectroscopy

Harkness, L., Novikov, S. M., Beermann, J., Bozhevolnyi, S. I. & Kassem, M., 2012, I : Stem Cells and Development. 21, 12, s. 2152-9 9 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Microscopy
Stromal Cells
Human Embryonic Stem Cells

Identification of a Predictive Molecular Signature For Ex Vivo Migration of Human Mesenchymal Stromal Cells

Andersen, R. K., Zaher, W., Larsen, K. H., Kassem, M. & Abdallah, B., 2012.

Publikation: Konferencebidrag uden forlag/tidsskriftKonferenceabstrakt til konferenceForskning

MECHANISMS IN ENDOCRINOLOGY MicroRNAs: Targets for enhancing osteoblast differentiation and bone formation

Taipaleenmäki, H., Bjerre, L., Chen, L., Kauppinen, S. & Kassem, M., 2012, I : European Journal of Endocrinology. 166, 3, s. 359-71 22 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Osteoblasts
MicroRNAs
Osteogenesis
Apoptosis

Mesenchymal Stem Cells: Application for Immunomodulation and Tissue Repair

Horwood, N. J., Dazzi, F., Zaher, W. & Kassem, M., 2012, Tissue and Cell Clinical Use: An Essential Guide . Warwick, R. M. & Brubaker, S. A. (red.). Wiley-Blackwell, s. 332-357

Publikation: Bidrag til bog/antologi/rapport/konference-proceedingBidrag til bog/antologiForskningpeer review

Mesenchymal Stromal Cells
Graft vs Host Disease
Mesoderm
Stromal Cells
Chondrocytes

Microcarrier-based expansion process for hMSCs with high vitality and undifferentiated characteristics

Elseberg, C. L., Leber, J., Salzig, D., Wallrapp, C., Kassem, M., Kraume, M. & Czermak, P., 2012, I : International Journal of Artificial Organs. 35, 2, s. 93-107 15 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Stem cells
Mesenchymal Stromal Cells
Glucose
Carrier concentration
Biomass

Mouse Embryonic Fibroblasts (MEF) Exhibit a Similar but not Identical Phenotype to Bone Marrow Stromal Stem Cells (BMSC)

Saeed, H., Taipaleenmäki, H., Aldahmash, A. M., Abdallah, B. M. & Kassem, M., 2012, I : Stem Cell Reviews. 8, 2, s. 318-28 11 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Mesenchymal Stromal Cells
Fibroblasts
Chondrocytes
Osteoblasts
Adipocytes

Procedures for Derivation and Characterisation of Human Embryonic Stem Cells from Odense, Denmark

Harkness, L. & Kassem, M., 2012, Human Embryonic Stem Cells Handbook: Methods in Molecular Biology. Turksen, K. (red.). Springer Science+Business Media, s. 33-51 (Methods in Molecular Medicine, Bind 873).

Publikation: Bidrag til bog/antologi/rapport/konference-proceedingBidrag til bog/antologiForskning

Denmark
Cell Line
Cell Biology
Flow Cytometry
Polymerase Chain Reaction

Sarcomas as a mise en abyme of mesenchymal stem cells: Exploiting interrelationships for cell mediated anticancer therapy

Burns, J. S., Safwat, A. A., Grisendi, G., Kassem, M. & Dominici, M., 2012, I : Cancer Letters. 325, 1, s. 1-10 10 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Mesenchymal Stromal Cells
Entosis
Sarcoma
Cell Fusion
Growth

Separate developmental programs for HLA-A and -B expression during diffenrentiation from embryonic stem cells to lymphocytes, adipocytes and osteocytes

Sabir, H. J., Isa, A., Nehlin, J., Qanie, D. W. M., Prokhorova, T., Kassem, M. & Barington, T., 31. maj 2012.

Publikation: Konferencebidrag uden forlag/tidsskriftKonferenceabstrakt til konferenceForskningpeer review

Serum levels of fetal antigen 1 in extreme nutritional States

Andries, A., Niemeier, A., Støving, R. K., Abdallah, B. M., Wolf, A-M., Hørder, K. & Kassem, M., 2012, I : International Scholarly Research Notices. 2012, s. 592648

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Morbid Obesity
Serum
Weights and Measures
Insulin
Weight Gain

Stable isotope labelling with amino acids in cell culture for human embryonic stem cell proteomic analysis

Harkness, L., Prokhorova, T. A., Kassem, M. & Blagoev, B., 2012, I : Methods in Molecular Biology. 873, s. 297-305 9 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskning

Isotope Labeling
Amino Acids
Proteins
Membranes
Human Embryonic Stem Cells

Temporal Profiling and Pulsed SILAC Labeling Identify Novel Secreted Proteins during ex vivo Osteoblast Differentiation of Human Stromal Stem Cells

Kristensen, L. P., Chen, L., Nielsen, M. O., Qanie, D. W., Kratchmarova, I., Kassem, M. & Andersen, J. S., 2012, I : Molecular and Cellular Proteomics. 11, 10, s. 989-1007 19 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Osteoblasts
Stromal Cells
Stem cells
Labeling
Proteins

The Cross-talk Between TGF-β1 and Dlk1 Mediates Early Chondrogenesis During Embryonic Endochondral Ossification

Taipaleenmaki, H., M, L., Chen, L., Larsen, K. H., Säämänen, A. M., Kassem, M. & Abdallah, B., 2012, I : Stem Cells. 30, 2, s. 304-13 10 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Chondrogenesis
Osteogenesis
Fibroblasts
Chondrocytes
Limb Buds

The Histone H2B Monoubiquitination Regulatory Pathway Is Required for Differentiation of Multipotent Stem Cells

Karpiuk, O., Najafova, Z., Kramer, F., Hennion, M., Galonska, C., König, A., Snaidero, N., Vogel, T., Shchebet, A., Begus-Nahrmann, Y., Kassem, M., Simons, M., Shcherbata, H., Beissbarth, T. & Johnsen, S. A., 2012, I : Molecular Cell. 46, 5, s. 705-13 9 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Mesenchymal Stromal Cells
Histones
Cell Differentiation
Cell Lineage
Ligases

Tumour microenvironment and radiation response in sarcomas originating from tumourigenic human mesenchymal stem cells

D'Andrea, F. P., Safwat, A. A., Burns, J. S., Kassem, M., Horsman, M. R. & Overgaard, J., 2012, I : International Journal of Radiation Biology. 88, 6, s. 457-65 9 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Mesenchymal Stromal Cells
Sarcoma
Clone Cells
Neoplasms
Intrinsic Factor
2013

Cell-based delivery of glucagon-like peptide-1 using encapsulated mesenchymal stem cells

Wallrapp, C., Thoenes, E., Thürmer, F., Jork, A., Kassem, M. & Geigle, P., 17. sep. 2013, I : Journal of Microencapsulation. 30, 4, s. 315-24

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Glucagon-Like Peptide 1
stem cells
Stem cells
Mesenchymal Stromal Cells
Peptides

Comparison between various biomarkers of senescence in bone marrow-derived stromal cells in vitro and ex-vivo

Nehlin, J., Kassem, M. & Frary, C., 6. sep. 2013.

Publikation: Konferencebidrag uden forlag/tidsskriftKonferenceabstrakt til konferenceForskningpeer review

Mesenchymal Stromal Cells
Galactosidases
Fixatives
Cell Aging
Poisons

Dual role of delta-like 1 homolog (DLK1) in skeletal muscle development and adult muscle regeneration

Andersen, D. C., Laborda, J., Baladron, V., Kassem, M., Sheikh, S. P. & Jensen, C. H., 2013, I : Development. 140, 18, s. 3743-3753

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Muscle Development
Skeletal Muscle
Muscles
Adipogenesis
Fats

Human Stromal (Mesenchymal) Stem Cells from Bone Marrow, Adipose Tissue and Skin Exhibit Differences in Molecular Phenotype and Differentiation Potential

Al-Nbaheen, M., Vishnubalaji, R., Ali, D., Bouslimi, A., Al-Jassir, F., Megges, M., Prigione, A., Adjaye, J., Kassem, M. & Aldahmash, A., 14. apr. 2013, I : Stem Cell Reviews. 9, 1, s. 32-43

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Mesenchymal Stromal Cells
Adipose Tissue
Stromal Cells
Skin
Adipocytes

Identification of differentiation-stage specific molecular markers for the osteoblastic phenotype

Twine, N., Chen, L., Wilkins, M. & Kassem, M., 7. okt. 2013. 1 s.

Publikation: Konferencebidrag uden forlag/tidsskriftPosterForskningpeer review

Mesenchymal Stromal Cells
Osteogenesis
RNA Sequence Analysis
Gene Ontology
Extracellular Matrix Proteins

Mesenchymal stem cells in oral reconstructive surgery: a systematic review of the literature

Jakobsen, C., Sørensen, J. A., Kassem, M. & Thygesen, T. H., 2013, I : Journal of Oral Rehabilitation. 40, 9, s. 693-706 14 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Mesenchymal Stromal Cells
Alveolar Ridge Augmentation
Clinical Trials
Third Molar
Tissue Engineering
491 Downloads (Pure)

Pleiotropic effects of cancer cells' secreted factors on human stromal (mesenchymal) stem cells

Al-toub, M., Almusa, A., Almajed, M., Al-Nbaheen, M., Kassem, M., Aldahmash, A. & Alajez, N., 2013, I : Stem Cell Research & Therapy. 4, 114, 19 s., 24405819.

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Fil
Stem cells
Mesenchymal Stromal Cells
Tumors
Cells
Conditioned Culture Medium

Separate Developmental Programs for HLA-A and -B Cell Surface Expression during Differentiation from Embryonic Stem Cells to Lymphocytes, Adipocytes and Osteoblasts

Sabir, H. J., Nehlin, J. O., Qanie, D., Harkness, L., Prokhorova, T. A., Blagoev, B., Kassem, M., Isa, A. & Barington, T., 2013, I : P L o S One. 8, 1, s. e54366

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

HLA-A Antigens
Lymphocytes
osteoblasts
Osteoblasts
embryonic stem cells

Spatially controlled delivery of siRNAs to stem cells in implants generated by multi-component additive manufacturing

Andersen, M. Ø., Le, D. Q. S., Chen, M., Nygaard, J. V., Kassem, M., Bünger, C. & Kjems, J., 2013, I : Advanced Functional Materials. 23, 45, s. 5599-5607 9 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review