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2019
41 Downloads (Pure)

Age‐dependent DNA methylation patterns on the Y chromosome in elderly males

Lund, J. B., Li, S., Christensen, K., Mengel-From, J., Thinggaard, M. S., Marioni, R. E., Starr, J., Pattie, A., Deary, I. J., Baumbach, J. & Tan, Q., 2019, I : Aging Cell. 8 s.

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DNA Methylation
Epigenomics
Sex Characteristics
5 Downloads (Pure)

DNA methylome profiling in identical twin pairs discordant for body mass index

Li, W., Zhang, D., Wang, W., Wu, Y., Mohammadnejad, A., Lund, J., Baumbach, J., Christiansen, L. & Tan, Q., dec. 2019, I : International Journal of Obesity. 43, 12, s. 2491-2499

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Monozygotic Twins
Body Mass Index
DNA Methylation
Epigenomics
Adiposity
95 Downloads (Pure)

DNA methylome profiling of all-cause mortality in comparison with age-associated methylation patterns

Lund, J., Li, S., Baumbach, J., Svane, A. M., Hjelmborg, J. V. B., Christiansen, L., Christensen, K., Redmond, P., Marioni, R. E., Deary, I. J. & Tan, Q., 8. feb. 2019, I : Clinical Epigenetics. 11, 8 s., 23.

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DNA Methylation
Genome-Wide Association Study
Survival Analysis
Proportional Hazards Models
Epigenomics
27 Downloads (Pure)

Enriched power of disease-concordant twin-case-only design in detecting interactions in genome-wide association studies

Li, W., Baumbach, J., Mohammadnejad, A., Brasch-Andersen, C., Vandin, F., Korbel, J. O. & Tan, Q., 1. apr. 2019, I : European Journal of Human Genetics. 27, 4, s. 631-636

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Dizygotic Twins
Genome-Wide Association Study
Sample Size
Siblings
Monozygotic Twins

Epigenetic association analysis of clinical sub-phenotypes in patients with polycystic ovary syndrome (PCOS)

Jacobsen, V. M., Li, S., Wang, A., Zhu, D., Liu, M., Thomassen, M., Kruse, T. A. & Tan, Q., 3. aug. 2019, I : Gynecological Endocrinology. 35, 8, s. 691-694

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Polycystic Ovary Syndrome
Epigenomics
DNA Methylation
HLA-G Antigens
Chromosomes, Human, Pair 19
125 Downloads (Pure)

Epigenome-wide association study of depression symptomatology in elderly monozygotic twins

Starnawska, A., Tan, Q., Sørensen, M., McGue, M., Mors, O., Børglum, A. D., Christensen, K., Nyegaard, M. & Christiansen, L., 2. sep. 2019, I : Translational Psychiatry. 9, 1, 14 s., 214.

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Monozygotic Twins
Depression
DNA Methylation
Epigenomics
Flow Cytometry
54 Downloads (Pure)
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Monozygotic Twins
Cell Differentiation
HLA-C Antigens
Comb and Wattles
Nucleic Acid Regulatory Sequences

Genomisk medicin og kunstig intelligens

Kruse, T. A., Larsen, M. J., Tan, Q., Andersen, L. & Thomassen, M., 1. apr. 2019, I : Ugeskrift for Laeger. 181, 7A, V02190085.

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Medicine
Datasets
Clinical Decision-Making
Monozygotic Twins
Immune System Diseases
Transcriptome
Individuality
Cognition

Global microRNA profiling of metastatic conjunctival melanoma

Mikkelsen, L. H., Andersen, M., Andreasen, S., Larsen, A-C., Tan, Q., Toft, P. B., Wadt, K. & Heegaard, S., okt. 2019, I : Melanoma Research. 29, 5, s. 465-473

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MicroRNAs
Melanoma
Down-Regulation
Neoplasms
Referral and Consultation

Heritability of Age-Related Hearing Loss in Middle-Aged and Elderly Chinese: A Population-Based Twin Study

Duan, H., Zhang, D., Liang, Y., Xu, C., Wu, Y., Tian, X., Pang, Z., Tan, Q., Li, S. & Qiu, C., 1. mar. 2019, I : Ear and Hearing. 40, 2, s. 253-259

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Twin Studies
Hearing
Population
Dizygotic Twins
Developed Countries

Impact of obesity and physical inactivity on the long-term change in grip strength among middle-aged and older European adults

Wang, T., Feng, W., Li, S., Tan, Q., Zhang, D. & Wu, Y., 1. jul. 2019, I : Journal of Epidemiology & Community Health. 73, 7, s. 619-624

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Exercise
Retirement
Health Surveys
Surveys and Questionnaires

Longitudinal analysis of sibling correlation on blood pressure using mixed modeling

Tan, Q., Duan, H., Wang, A., Zhu, D. & Li, S., 2019, I : Annals of Epidemiology. 33, s. 49-53

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Longitudinal Studies
79 Downloads (Pure)

Longitudinal changes in the genetic and environmental influences on the epigenetic clocks across old age: Evidence from two twin cohorts

Jylhävä, J., Hjelmborg, J., Sørensen, M., Munoz, E., Tan, Q., Kuja-Halkola, R., Mengel-From, J., Christensen, K., Christiansen, L., Hägg, S., Pedersen, N. L. & Reynolds, C. A., feb. 2019, I : EBioMedicine. 40, s. 710-716

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Epigenomics
Clocks
Research
DNA Methylation
Epidemiology

Network based analysis of microarray gene expression profiles in response to electroacupuncture

Mohammadnejad, A., Li, S., Duan, H. & Tan, Q., 4. sep. 2019, I : Journal of Traditional and Complementary Medicine. 7 s.

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Electroacupuncture
Transcriptome
Periaqueductal Gray
Gene Ontology
80 Downloads (Pure)

Sex and age specific reduction in stress resistance and mitochondrial DNA copy number in Drosophila melanogaster

Kristensen, T. N., Loeschcke, V., Tan, Q., Pertoldi, C. & Mengel-From, J., 23. aug. 2019, I : Scientific Reports. 9, 7 s., 12305.

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stress tolerance
Drosophila melanogaster
mitochondrial DNA
gender
age structure

The CODATwins Project: The Current Status and Recent Findings of COllaborative Project of Development of Anthropometrical Measures in Twins

The CODATwins Project, 13. jul. 2019, I : Twin Research and Human Genetics.

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Smoking
Term Birth
Education
Dizygotic Twins
Weights and Measures

The epigenome of twins as a perfect laboratory for studying behavioural traits

Tan, Q., 2019, I : Neuroscience & Biobehavioral Reviews. 107, s. 192-195

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epigenetics
human behavior
epidemiology
experimental design
environmental impact

Weak Grip Strength and Cognition Predict Functional Limitation in Older Europeans

Wang, T., Wu, Y., Li, W., Li, S., Sun, Y., Li, S., Zhang, D. & Tan, Q., jan. 2019, I : Journal of the American Geriatrics Society. 67, 1, s. 93-99

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Cognition
Linear Models
Retirement
Health Surveys
Israel
Twin Studies
2018
52 Downloads (Pure)

A Case-only Genome-Wide Association Study on Gene-Sex Interaction in Allergic Rhinitis

Mohammadnejad, A., Brasch-Andersen, C., Li, W., Haagerup, A., Baumbach, J. & Tan, Q., sep. 2018, I : Annals of Allergy, Asthma, & Immunology. 121, 3, s. 366-367.e2

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Adenoid cystic carcinomas of the salivary gland, lacrimal gland, and breast are morphologically and genetically similar but have distinct microRNA expression profiles

Andreasen, S., Tan, Q., Agander, T. K., Steiner, P., Bjørndal, K., Høgdall, E., Larsen, S. R., Erentaite, D., Olsen, C. H., Ulhøi, B. P., von Holstein, S. L., Wessel, I., Heegaard, S. & Homøe, P., aug. 2018, I : Modern Pathology. 31, 8, s. 1211–1225

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Lacrimal Apparatus
Adenoid Cystic Carcinoma
MicroRNAs
Neoplasms
Glandular and Epithelial Neoplasms

Age-dependent patterns of X chromosome DNA methylation in the elderly.

Li, S. & Tan, Q., 2018. 1 s.

Publikation: Konferencebidrag uden forlag/tidsskriftPosterForskningpeer review

DNA Methylation
X Chromosome Inactivation
Age Factors
Scotland
Epigenomics
78 Downloads (Pure)

Association of current and former smoking with body mass index: A study of smoking discordant twin pairs from 21 twin cohorts

Piirtola, M., Jelenkovic, A., Latvala, A., Sund, R., Honda, C., Inui, F., Watanabe, M., Tomizawa, R., Iwatani, Y., Ordoñana, J. R., Sánchez-Romera, J. F., Colodro-Conde, L., Tarnoki, A. D., Tarnoki, D. L., Martin, N. G., Montgomery, G. W., Medland, S. E., Rasmussen, F., Tynelius, P., Tan, Q. & 30 flere, Zhang, D., Pang, Z., Rebato, E., Stazi, M. A., Fagnani, C., Brescianini, S., Busjahn, A., Harris, J. R., Brandt, I., Nilsen, T. S., Cutler, T. L., Hopper, J. L., Corley, R. P., Huibregtse, B. M., Sung, J., Kim, J., Lee, J., Lee, S., Gatz, M., Butler, D. A., Franz, C. E., Kremen, W. S., Lyons, M. J., Magnusson, P. K. E., Pedersen, N. L., Dahl Aslan, A. K., Öncel, S. Y., Aliev, F., Derom, C. A. & Vlietinck, R. F., 2018, I : PLOS ONE. 13, 7, 17 s., e0200140.

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body mass index
Body Mass Index
Smoking
confidence interval
Confidence Intervals
133 Downloads (Pure)

Association of miR-548c-5p, miR-7-5p, miR-210-3p, miR-128-3p with recurrence in systemically untreated breast cancer

Block, I., Burton, M., Sørensen, K. P., Andersen, L., Larsen, M. J., Bak, M., Cold, S., Thomassen, M., Tan, Q. & Kruse, T. A., 6. feb. 2018, I : OncoTarget. 9, 10, s. 9030-9042

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Body Mass Index
Monozygotic Twins
Twin Studies
Genome-Wide Association Study
Environmental Exposure

Circulating, Cell-Free Micro-RNA Profiles Reflect Discordant Development of Dementia in Monozygotic Twins

Mengel-From, J., Rønne, M. E., Carlsen, A. L., Skogstrand, K., Larsen, L. A., Tan, Q., Christiansen, L., Christensen, K. & Heegaard, N. H. H., 1. jan. 2018, I : Journal of Alzheimer's disease : JAD. 63, 2, s. 591-601

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Monozygotic Twins
MicroRNAs
Immunoassay
Lipoproteins
Longitudinal Studies
Åben adgang
Twin Studies
MicroRNAs
Cognition
Neurobiology
Monozygotic Twins
100 Downloads (Pure)

Differential effect of surgical manipulation on gene expression in normal breast tissue and breast tumor tissue

Pedersen, I. S., Thomassen, M., Tan, Q., Kruse, T. A., Thorlacius-Ussing, O., Garne, J. P. & Krarup, H. B., 16. nov. 2018, I : Molecular Medicine. 24, 8 s., 57.

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Neoplasms
Gene Expression Profiling
Transcriptome
Freezing

DiMmer: Discovery of Differentially Methylated Regions in Epigenome-Wide Association Study (EWAS) Data

Frisch, T., Møller Gøttcke, J., Röttger, R., Tan, Q. & Baumbach, J., 2018, Data Mining for Systems Biology: Methods and Protocols. Mamitsuka, H. (red.). Humana Press, s. 51-62 (Methods in Molecular Biology, Bind 1807).

Publikation: Bidrag til bog/antologi/rapport/konference-proceedingBidrag til bog/antologiForskningpeer review

Programming Languages
DNA Methylation
Random Allocation
67 Downloads (Pure)

DNA methylation age and perceived age in elderly Danish twins

Debrabant, B., Sørensen, M., Christiansen, L., Tan, Q., McGue, M., Christensen, K. & Hjelmborg, J. V. B., 1. jan. 2018, I : Mechanisms of Ageing and Development. 169, s. 40-44

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DNA Methylation
Epigenomics
142 Downloads (Pure)

DNA Methylation and All-Cause Mortality in Middle-Aged and Elderly Danish Twins

Svane, A. M., Soerensen, M., Lund, J., Tan, Q., Jylhävä, J., Wang, Y., Pedersen, N. L., Hägg, S., Debrabant, B., Deary, I. J., Christensen, K., Christiansen, L. & Hjelmborg, J. B., 8. feb. 2018, I : Genes. 9, 2, 15 s., 78.

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DNA Methylation
Twin Studies
Monozygotic Twins
Population

DNA methylation linked to all-cause mortality in older people: An epigenome-wide association study.

Lund, J., Baumbach, J. & Tan, Q., mar. 2018.

Publikation: Konferencebidrag uden forlag/tidsskriftPosterForskningpeer review

DNA Methylation
G-Protein-Coupled Receptors
Proportional Hazards Models
Epigenomics
Skeleton
111 Downloads (Pure)

Epigenetic signature of preterm birth in adult twins

Tan, Q., Li, S., Frost, M., Nygaard, M., Soerensen, M., Larsen, M., Christensen, K. & Christiansen, L., 2018, I : Clinical Epigenetics. 10, 10 s., 87.

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Premature Birth
Epigenomics
Health
Chromosomes, Human, Pair 5
Chromosomes, Human, Pair 3

Epigenetic signature of preterm birth in adult twins.

Tan, Q. & Li, S., 2018. 1 s.

Publikation: Konferencebidrag uden forlag/tidsskriftPosterForskningpeer review

Premature Birth
Epigenomics
Health
Chromosomes, Human, Pair 5
Chromosomes, Human, Pair 3

Gene methylation co-regulation network analysis of all-cause mortaltiy in ageing individuals

Lund, J., Baumbach, J. & Tan, Q., 16. okt. 2018.

Publikation: Konferencebidrag uden forlag/tidsskriftPosterForskningpeer review

Proportional Hazards Models
DNA Methylation
Epigenomics
Population

Genetic and environmental influences on cardiovascular risk factors and cognitive function: A Chinese twin aging study

Xu, C., Tian, X., Sun, J., Wu, Y., Zhang, D., Pang, Z., Li, S., Petersen, I., Mengel-From, J., Christiansen, L., Christensen, K. & Tan, Q., feb. 2018, I : Geriatrics & Gerontology International. 18, 2, s. 352-359

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Twin Studies
Cognition
cognition
HDL Cholesterol
environmental factors
136 Downloads (Pure)

Genetic rearrangements, hotspot mutations, and microRNA expression in the progression of metastatic adenoid cystic carcinoma of the salivary gland

Andreasen, S., Agander, T. K., Bjørndal, K., Erentaite, D., Heegaard, S., Larsen, S. R., Melchior, L. C., Tan, Q., Ulhøi, B. P., Wessel, I. & Homøe, P., 13. apr. 2018, I : Oncotarget. 9, 28, s. 19675-19687

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Adenoid Cystic Carcinoma
MicroRNAs
Mutation
Neoplasms
103 Downloads (Pure)

Genetics of Obesity Traits: A Bivariate Genome-Wide Association Analysis

Wu, Y., Duan, H., Tian, X., Xu, C., Wang, W., Jiang, W., Pang, Z., Zhang, D. & Tan, Q., 16. maj 2018, I : Frontiers in Genetics. 9, MAY, 9 s., 179.

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Genome-Wide Association Study
Dizygotic Twins
Body Mass Index
Twin Studies
Quantitative Trait Loci
129 Downloads (Pure)

Heritability and Genome-Wide Association Analyses of Serum Uric Acid in Middle and Old-Aged Chinese Twins

Wang, W., Zhang, D., Xu, C., Wu, Y., Duan, H., Li, S. & Tan, Q., 6. mar. 2018, I : Frontiers in Endocrinology. 9, MAR, 12 s., 75.

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Genome-Wide Association Study
Uric Acid
Serum
Single Nucleotide Polymorphism
Chromosomes, Human, Pair 14

MicroRNA dysregulation in adenoid cystic carcinoma of the salivary gland in relation to prognosis and gene fusion status: a cohort study

Andreasen, S., Tan, Q., Agander, T. K., Thomas V. O., H., Steiner, P., Bjørndal, K., Høgdall, E., Larsen, S. R., Erentaite, D., Olsen, C. H., Ulhøi, B. P., Heegaard, S., Wessel, I. & Homøe, P., sep. 2018, I : Virchows Archiv. 473, 3, s. 329-340

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Adenoid Cystic Carcinoma
MicroRNAs
Cohort Studies
Neoplasms
Survival Analysis

Network analysis of DNA methylation of visceral adipose tissue comparing obese individuals with and without type 2 diabetes

Mohammadnejad, A., Li, W., Lund, J., Baumbach, J. & Tan, Q., 25. sep. 2018.

Publikation: Konferencebidrag uden forlag/tidsskriftPosterForskningpeer review

Online interactive microbial classification and geospatial distributional analysis using BioAtlas

Lund, J., Tan, Q. & Baumbach, J., 2018, Data Mining for Systems Biology: Methods and Protocols. Mamitsuka, H. (red.). New York: Humana Press, Bind 1807. s. 21-35 (Methods in Molecular Biology, Bind 1807).

Publikation: Bidrag til bog/antologi/rapport/konference-proceedingBidrag til bog/antologiForskningpeer review

Databases
rRNA Genes
16S Ribosomal RNA
Metagenomics
Datasets

On the power of epigenome-wide association studies using a disease-discordant twin design

Li, W., Christiansen, L., Hjelmborg, J. V. B., Baumbach, J. & Tan, Q., 1. dec. 2018, I : Bioinformatics. 34, 23, s. 4073–4078

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Diseases in Twins
Monozygotic Twins
DNA Methylation
Computational Biology
Epigenomics
140 Downloads (Pure)

Sex Differences in Genetic Associations With Longevity

Zeng, Y., Nie, C., Min, J., Chen, H., Liu, X., Ye, R., Chen, Z., Bai, C., Xie, E., Yin, Z., Lv, Y., Lu, J., Li, J., Ni, T., Bolund, L., Land, K. C., Yashin, A. I., O'Rand, A. M., Sun, L., Yang, Z. & 22 flere, Tao, W., Gurinovich, A., Franceschi, C., Xie, J., Gu, J., Hou, Y., Liu, X., Xu, X., Robine, J-M., Deelen, J., Sebastiani, P., Slagboom, E., Perls, T. T., Hauser, E. R., Gottschalk, W., Tan, Q., Christensen, K., Shi, X., Lutz, M., Tian, X-L., Yang, H. & Vaupel, J. W., aug. 2018, I : JAMA Network Open. 1, 4, 15 s., 1670.

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Sex Characteristics
Genome-Wide Association Study
Delivery of Health Care
Tryptophan
Case-Control Studies

Surfactant protein-D, a potential mediator of inflammation in axial spondyloarthritis

Munk, H. L., Fakih, D., Christiansen, L., Tan, Q., Christensen, A. F., Ejstrup, L., Loft, A. G., Junker, K., Kyvik, K. O., Jounblat, R., Holmskov, U., Sorensen, G. L. & Junker, P., 1. okt. 2018, I : Rheumatology (Oxford, England). 57, 10, s. 1861–1865

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Pulmonary Surfactant-Associated Protein D
Molecular Weight
Serum
Single Nucleotide Polymorphism
Smoking

Weighted gene co-expression network analysis of microarray mRNA expression profiling in response to electroacupuncture

Mohammadnejad, A., Li, S., Duan, H., Lund, J., Li, W., Baumbach, J. & Tan, Q., dec. 2018, Proceedings of the 2018 IEEE International Conference on Bioinformatics and Biomedicine. Schmidt, H., Griol, D., Wang, H., Baumbach, J., Zheng, H., Callejas, Z., Hu, X., Dickerson, J. & Zhang, L. (red.). IEEE, s. 1876-1883 8621258

Publikation: Bidrag til bog/antologi/rapport/konference-proceedingKonferencebidrag i proceedingsForskningpeer review

Electroacupuncture
Messenger RNA
Periaqueductal Gray
Gene Ontology
2017

A case-only genome-wide association study for assessing gene-sex interaction in Allergic rhinitis

Mohammadnejad, A., Brasch-Andersen, C., Haagerup, A., Vestbo, J., Baumbach, J. & Tan, Q., aug. 2017.

Publikation: Konferencebidrag uden forlag/tidsskriftPosterForskningpeer review

Genome-Wide Association Study
Single Nucleotide Polymorphism
Chromosomes, Human, Pair 12
Posters
Chromosomes, Human, Pair 5