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Absence of an osteopetrosis phenotype in IKBKG (NEMO) mutation-positive women: A case-control study

Frost, M., Tencerova, M., Andreasen, C. M., Levin Andersen, T., Ejersted, C. A., Svaneby, D., Kassem, M., Whyte, M. P. & Frederiksen, A. L., apr. 2019, I : Bone. 121, s. 243-254

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

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Osteopetrosis
Case-Control Studies
Mutation
Incontinentia Pigmenti
X Chromosome Inactivation
165 Downloads (Pure)

Actin depolymerization enhances adipogenic differentiation in human stromal stem cells

Chen, L., Hu, H., Qiu, W., Shi, K. & Kassem, M., 1. maj 2018, I : Stem Cell Research. 29, s. 76-83

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

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Stromal Cells
Adipocytes
Actins
Phalloidine
Cytochalasin D
Wnt Signaling Pathway
MAP Kinase Signaling System
Stem cells
Mesenchymal Stromal Cells
Bone

Adult Stromal (Skeletal, Mesenchymal) Stem Cells: Advances Towards Clinical Applications.

Jafari, A., Harkness, L., Zaher, W. & Kassem, M., maj 2014, Adult Stem Cells, Stem Cell Biology and Regenerative Medicine. Turksen, K. (red.). Springer Science+Business Media, s. 359-373 15 s.

Publikation: Bidrag til bog/antologi/rapport/konference-proceedingBidrag til bog/antologiForskningpeer review

Aging and bone

Gimble, J. M., Floyd, Z. E., Kassem, M. & Nuttall, M. E., 2016, Osteoporosis in Older Persons: Advances in Pathophysiology and Therapeutic Approaches. Duque, G. & Kiel, D. P. (red.). 2. udg. Springer, s. 23-42

Publikation: Bidrag til bog/antologi/rapport/konference-proceedingBidrag til bog/antologiForskningpeer review

Aging and lineage allocation changes of bone marrow skeletal (stromal) stem cells

Nehlin, J. O., Jafari, A., Tencerova, M. & Kassem, M., 1. jun. 2019, I : Bone. 123, s. 265-273

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Stromal Cells
Adipocytes
Physiological Phenomena
Adiposity
Osteoblasts

Anabolic compounds for treating and preventing bone loss diseases

Jafari, A., Chen, L., Kassem, M. & Abdallah, B., 7. maj 2015, Patentnr. WO2013167475 (A1), 7. maj 2015, Prioritetsdato 3. maj 2013, Prioritetsnr. US201314399726

Publikation: Patent

130 Downloads (Pure)

Antibody-based inhibition of circulating DLK1 protects from estrogen deficiency-induced bone loss in mice

Figeac, F., Andersen, D. C., Nipper Nielsen, C. A., Ditzel, N., Sheikh, S. P., Skjødt, K., Kassem, M., Jensen, C. H. & Abdallah, B. M., maj 2018, I : Bone. 110, s. 312-320

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Estrogens
Osteogenesis
Serum
X-Ray Microtomography
Adipogenesis

An update of human mesenchymal stem cell biology and their clinical uses

Zaher, W., Harkness, L., Jafari, A. & Kassem, M., maj 2014, I : Archives of Toxicology. 88, 5, s. 1069-82

Publikation: Bidrag til tidsskriftReviewForskningpeer review

Cytology
Stem cells
Mesenchymal Stromal Cells
Cell Biology
Stromal Cells
92 Downloads (Pure)

A simple and reliable protocol for long-term culture of murine bone marrow stromal (mesenchymal) stem cells that retained their in vitro and in vivo stemness in long-term culture

Abdallah, B. M., Alzahrani, A. M., Abdel-Moneim, A. M., Ditzel, N. & Kassem, M., feb. 2019, I : Biological Procedures Online. 21, 11 s., 3.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

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Mesenchymal Stromal Cells
Osteoblasts
Population
Fibroblast Growth Factor 2
Stromal Cells

A small scale cell culture system to analyze mechanobiology using reporter gene constructs and polyurethane dishes

Seefried, L., Mueller-Deubert, S., Wentzer, T. S., Lind, T., Mentrup, B., Kober, M., Docheva, D., Liedert, A., Kassem, M., Ignatius, A., Schieker, M., Claes, L., Wilke, W., Jakob, F. & Ebert, R., 1. jan. 2010, I : European Cells & Materials. 20, s. 344-55 12 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Polyurethanes
Bioreactors
Reporter Genes
Cell culture
Signal transduction
80 Downloads (Pure)

Association between in vivo bone formation and ex vivo migratory capacity of human bone marrow stromal cells

Andersen, R. K., Zaher, W., Larsen, K. H., Ditzel, N., Drews, K., wruck, W., Adjaye, J., Abdallah, B. & Kassem, M., 8. okt. 2015, I : Stem Cell Research & Therapy. 6, s. 196

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

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Mesenchymal Stromal Cells
Osteogenesis
Bone
Clone Cells
Platelet-Derived Growth Factor Receptors
Adipogenesis
Stem Cell Factor
Osteogenesis
Color

Bioactive implants: RNA interference as a tool to direct stem cell differentiation.

Dillschneider, P., Andersen, M. Ø., Kjems, J. & Kassem, M., 2012, I : Journal of Tissue Engineering and Regenerative Medicine. 6, S1, s. 292 1 s., 49.P05.

Publikation: Bidrag til tidsskriftKonferenceabstrakt i tidsskriftForskningpeer review

79 Downloads (Pure)

Bioactive Nano-fibrous Scaffold for Vascularized Craniofacial Bone Regeneration

Prabha, R. D., Kraft, D. C. E., Harkness, L., Melsen, B., Varma, H., Nair, P. D., Kjems, J. & Kassem, M., mar. 2018, I : Journal of Tissue Engineering and Regenerative Medicine. 12, 3, s. e1537-e1548

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Polyvinyl Alcohol
Bioceramics
Durapatite
Scaffolds
Polyvinyl alcohols

Bone and Skeletal Stem Cells are Affected in High Fat Diet Mice

Figeac, F., Tencerova, M., Ditzel, N., Nielsen, T. K. L., Jørgensen, B. & Kassem, M., 2017. 1 s.

Publikation: Konferencebidrag uden forlag/tidsskriftPosterForskning

273 Downloads (Pure)

Bone morphogenetic protein 2 (BMP2) induces growth suppression and enhances chemosensitivity of human colon cancer cells

Vishnubalaji, R., Yue, S., Alfayez, M., Kassem, M., Liu, FF., Aldahmash, A. & Alajez, N. M., 2016, I : Cancer Cell International. 16, 12 s., 77.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

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Colonic Neoplasms
Colorectal Neoplasms
Growth
SCID Mice
Computational Biology

Bone morphology in IKBKG (NEMO) mutation positive women: A case-control study

Frost, M., Tencerova, M., Ejersted, C. A., Svaneby, D., Levin Andersen, T., Kassem, M., McAlister, W. H., Novack, D. V., Whyte, M. P. & Frederiksen, A. L., dec. 2017, I : Journal of Bone and Mineral Research. 32, S1, s. S395 1 s., MO0710.

Publikation: Bidrag til tidsskriftKonferenceabstrakt i tidsskriftForskningpeer review

Bone morphology in IKBKG (NEMO) mutation positive women: A case-control study

Frost, M., Tencerova, M., Ejersted, C. A., Svaneby, D., Levin Andersen, T., Kassem, M., McAlister, W. H., Novack, D., Whyte, M. P. & Frederiksen, A. L., 2017.

Publikation: Konferencebidrag uden forlag/tidsskriftPosterForskningpeer review

Bone regeneration and stem cells

Arvidson, K., Abdallah, B. M., Applegate, L. A., Baldini, N., Cenni, E., Gomez-Barrena, E., Granchi, D., Kassem, M., Konttinen, Y. T., Mustafa, K. A., Pioletti, D. P., Sillat, T. & Finne-Wistrand, A., 2011, I : Journal of Cellular and Molecular Medicine. 15, 4, s. 718-746

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Mesenchymal Stromal Cells
Fetal Stem Cells
Fracture Healing
Platelet-Rich Plasma
Tissue Engineering

Cancer stem cell overexpression of nicotinamide N-methyltransferase enhances cellular radiation resistance

D'Andrea, F. P., Safwat, A., Kassem, M., Gautier, L., Overgaard, J. & Horsman, M. R., 1. jun. 2011, I : Radiotherapy & Oncology. 99, 3, s. 373-8 6 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Mesenchymal Stromal Cells
Seeds
Clone Cells
Population
88 Downloads (Pure)

CD146/MCAM defines functionality of human bone marrow stromal stem cell populations

Harkness, L., Zaher, W., Ditzel, N., Isa, A. & Kassem, M., 2016, I : Stem Cell Research & Therapy. 7, 1, s. 4-16 13 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

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Stem cells
Mesenchymal Stromal Cells
Bone
Population
Cells

CD146 expression on primary nonhematopoietic bone marrow stem cells is correlated with in situ localization

Tormin, A., Li, O., Brune, J. C., Walsh, S., Schütz, B., Ehinger, M., Ditzel, N., Kassem, M. & Scheding, S., 2011, I : Blood. 117, 19, s. 5067-77 11 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Mesenchymal Stromal Cells
Population
Stromal Cells
Cultured Cells
Fibroblasts
181 Downloads (Pure)

CD34 defines an osteoprogenitor cell population in mouse bone marrow stromal cells

Abdallah, B. M., Al-Shammary, A., Skagen, P., Abu Dawud, R., Adjaye, J., Aldahmash, A. & Kassem, M., 21. sep. 2015, I : Stem Cell Research. 15, 3, s. 449-458 10 s.

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Mesenchymal Stromal Cells
Osteoblasts
Population
Stromal Cells
Computational Biology
309 Downloads (Pure)

CDH1 and IL1-beta expression dictates FAK and MAPKK-dependent cross-talk between cancer cells and human mesenchymal stem cells

Al-toub, M., Vishnubalaji, R., Hamam, R., Kassem, M., Abdallah, B. & Alajez, N. M., 2015, I : Stem Cell Research & Therapy. 24, 6, s. 135

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Mitogen-Activated Protein Kinase Kinases
Stem cells
Mesenchymal Stromal Cells
Cells
Neoplasms

Cell-based delivery of glucagon-like peptide-1 using encapsulated mesenchymal stem cells

Wallrapp, C., Thoenes, E., Thürmer, F., Jork, A., Kassem, M. & Geigle, P., 17. sep. 2013, I : Journal of Microencapsulation. 30, 4, s. 315-24

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Glucagon-Like Peptide 1
stem cells
Stem cells
Mesenchymal Stromal Cells
Peptides

Cell shape and spreading of stromal (mesenchymal) stem cells cultured on fibronectin coated gold and hydroxyapatite surfaces

Dolatshahi-Pirouz, A., Jensen, T. H. L., Kolind, K., Bünger, C., Kassem, M., Foss, M. & Besenbacher, F., 2011, I : Colloids and Surfaces B: Biointerfaces. 84, 1, s. 18-25 8 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Cell Shape
stem cells
Durapatite
Stem cells
Mesenchymal Stromal Cells

Changes in left ventricular filling patterns after repeated injection of autologous bone marrow cells in heart failure patients

Diederichsen, A. C. P., Møller, J. E., Thayssen, P., Videbæk, L., Sækmose, S. G., Barington, T. & Kassem, M., 17. mar. 2010, I : Scandinavian Cardiovascular Journal. 44, 3, s. 139-145

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Plasma Volume
Brain Natriuretic Peptide
Outcome Assessment (Health Care)
564 Downloads (Pure)

Characterization of Cellular and Molecular Heterogeneity of Bone Marrow Stromal Cells

Elsafadi, M., Manikandan, M., Atteya, M., Hashmi, J. A., Iqbal, Z., Aldahmash, A., Alfayez, M., Kassem, M. & Mahmood, A., 2016, I : Stem Cells International. 2016, 18 s., 9378081.

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Mesenchymal Stromal Cells
Alkaline Phosphatase
Stromal Cells
Osteoblasts
Homeobox Genes

Characterization of programmed death ligands in immune modulation of mesenchymal stem cells

Isa, A., Sabir, H. J., Nehlin, J., Andersen, T. E., Kassem, M. & Barington, T., 25. maj 2010.

Publikation: Konferencebidrag uden forlag/tidsskriftPosterForskning

154 Downloads (Pure)

CHD1 regulates cell fate determination by activation of differentiation-induced genes

Baumgart, S. J., Najafova, Z., Hossan, T., Xie, W., Nagarajan, S., Kari, V., Ditzel, N., Kassem, M. & Johnsen, S. A., 2017, I : Nucleic Acids Research. 45, 13, s. 7722-7735

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DNA-Binding Proteins
Osteoblasts
Nucleosomes
RNA Polymerase II
Osteogenesis
88 Downloads (Pure)

Chromosome copy number variation in telomerized human bone marrow stromal cells; insights for monitoring safe ex-vivo expansion of adult stem cells

Burns, J. S., Harkness, L., Aldahmash, A., Gautier, L. & Kassem, M., 2017, I : Stem Cell Research. 25, s. 6-17

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Mesenchymal Stromal Cells
Diploidy
Comparative Genomic Hybridization
Cell Cycle Checkpoints
Computational Biology
156 Downloads (Pure)

Circulating microRNAs in breast cancer: novel diagnostic and prognostic biomarkers

Hamam, R., Hamam, D., Alsaleh, K. A., Kassem, M., Zaher, W., Alfayez, M., Aldahmash, A. & Alajez, N. M., 7. sep. 2017, I : Cell Death & Disease. 8, 9, 12 s., e3045.

Publikation: Bidrag til tidsskriftReviewForskningpeer review

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MicroRNAs
Physiologic Monitoring
Nucleic Acids
Messenger RNA
DNA

Circulating osteogenic cells: implications for injury, repair, and regeneration

Pignolo, R. J. & Kassem, M., 2011, I : Journal of Bone and Mineral Research. 26, 8, s. 1685-93 9 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Wounds and Injuries
Osteogenesis
Reading
87 Downloads (Pure)

Clinical improvement in a patient with monostotic melorheostosis after treatment with denosumab: a case report

Byberg, S., Abrahamsen, B., Kassem, M., Ralston, S. & Schwarz, P., 27. sep. 2018, I : Journal of Medical Case Reports. 12, 6 s., 278.

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Melorheostosis
zoledronic acid

Clinical study on the therapeutic role of midodrine in non azotemic cirrhotic patients with tense ascites: a double-blind, placebo-controlled, randomized trial

Ali, A., Farid, S., AminAmin, M., Kassem, M. & Al-Garem, NN., 2014, I : Hepato-Gastroenterology. 61, 135, s. 1915-1924

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Midodrine
Randomized Controlled Trials
Placebos
Clinical Studies
Hepatorenal Syndrome
155 Downloads (Pure)

Combined MSC and GLP-1 Therapy Modulates Collagen Remodeling and Apoptosis following Myocardial Infarction

Wright, E. J., Hodson, N. W., Sherratt, M. J., Kassem, M., Lewis, A. L., Wallrapp, C., Malik, N. & Holt, C. M., 2016, I : Stem Cells International. 2016, 13 s., 7357096.

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Mesenchymal Stromal Cells
Apoptosis
Atomic Force Microscopy
Conditioned Culture Medium
Polymerase Chain Reaction

Comparison between various biomarkers of senescence in bone marrow-derived stromal cells in vitro and ex-vivo

Nehlin, J., Kassem, M. & Frary, C., 6. sep. 2013.

Publikation: Konferencebidrag uden forlag/tidsskriftKonferenceabstrakt til konferenceForskningpeer review

Mesenchymal Stromal Cells
Galactosidases
Fixatives
Cell Aging
Poisons
109 Downloads (Pure)

Comparison of Regenerative Tissue Quality following Matrix-Associated Cell Implantation Using Amplified Chondrocytes Compared to Synovium-Derived Stem Cells in a Rabbit Model for Cartilage Lesions

Schmal, H., Kowal, J. M., Kassem, M., Seidenstuecker, M., Bernstein, A., Böttiger, K., Xiong, T., Südkamp, N. P. & Kubosch, E. J., 1. jan. 2018, I : Stem Cells International. 2018, 12 s., 4142031.

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Chondrocytes
Rabbits
Collagen Type X
Collagen Type II
Collagen Type I

Composites of fatty acids and ceramic powders are versatile biomaterials for personalized implants and controlled release of pharmaceuticals

Bonde Jensen, M., Slots, C., Ditzel, N., Albrektsen, O., Wiatr Borg, S., Thygesen, T., Kassem, M. & Andersen, M. Ø., jun. 2018, I : Bioprinting. 10, e00027.

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Fatty acids
Biomaterials
Powders
Drug products
Fatty Acids

Concise review: bridging the gap: bone regeneration using skeletal stem cell-based strategies-where are we now?

Dawson, J. I., Kanczler, J., Kassem, M. & Oreffo, R. O. C., 2014, I : Stem Cells. 32, 1, s. 35-44 24115290.

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Population
Cell Biology
Wounds and Injuries

Concise Review: Quiescence in Adult Stem Cells: Biological Significance and Relevance to Tissue Regeneration

Rumman, M., Dhawan, J. & Kassem, M., 2015, I : Stem Cells. 33, 10, s. 2903-12

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Cell Cycle
Homeostasis
Wounds and Injuries

Controlling drug release spatially and temporally in scaffolds

Andersen, M. Ø., Nygaard, J. V., Le, D. Q. S., Burns, J., Raarup, M. K., Chen, M., Howard, K. A., Bünger, C., Kassem, M. & Kjems, J., 2012, I : Journal of Tissue Engineering and Regenerative Medicine. 6, S1

Publikation: Bidrag til tidsskriftKonferenceabstrakt i tidsskriftForskningpeer review

108 Downloads (Pure)

Convergence of TGFβ and BMP signaling in regulating human bone marrow stromal cell differentiation

El-Safadi, M., Shinwari, T., Al-Malki, S., Manikandan, M., Mahmood, A., Aldahmash, A., Alfayez, M., Kassem, M. & Alajez, N. M., 21. mar. 2019, I : Scientific Reports. 9, 13 s., 4977.

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Mesenchymal Stromal Cells
Cell Differentiation
Up-Regulation
Regenerative Medicine
Gene Expression Profiling

CRMP4 Inhibits Bone Formation by Negatively Regulating BMP and RhoA Signaling

Abdallah, B. M., Figeac, F., Larsen, K. H., Ditzel, N., Keshari, P., Isa, A., Jafari, A., Andersen, T. L., Delaisse, J. M., Goshima, Y., Ohshima, T. & Kassem, M., maj 2017, I : Journal of Bone and Mineral Research. 32, 5, s. 913-926

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Osteoblasts
Osteogenesis
Proteins
Mesenchymal Stromal Cells
Cyclin D1

Cross-border biobanking: The German-Danish Interreg project BONEBANK

Maushagen, R., Gemoll, T., Oberlaender, M., Faccinetti, G., Figge, L., Kock-Schoppenhauer, A-K., Duhm-Harbeck, P., Niessen, L., Unger, A., Waizner, K., Wendlandt, R., Zweig, W., Kowal, J. M., Haakonsson, A., Bober, C., Diercks, K., Nassutt, R., Buescher, R., Reimers, N., Schmal, H. & 12 flere, Duckert, R., Kroeger, I., Stueck, G., Kessel, S., Hecht, M., Frahm, T., Eckers, A., Brilling, J., Barington, T., Kassem, M., Schulz, A-P. & Habermann, J. K., 2017. 1 s.

Publikation: Konferencebidrag uden forlag/tidsskriftPosterForskningpeer review

CUDC-907 Promotes Bone Marrow Adipocytic Differentiation Through Inhibition of Histone Deacetylase and Regulation of Cell Cycle

Ali, D., Alshammari, H., Vishnubalaji, R., Chalisserry, E. P., Hamam, R., Alfayez, M., Kassem, M., Aldahmash, A. & Alajez, N. M., 2017, I : Stem Cells and Development. 26, 5, s. 353-362

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Histone Deacetylases
Adipocytes
Cell Cycle
Mesenchymal Stromal Cells
Epigenomics

CXCR4 expression in human mesenchymal stem cells enhances in vitro migration

Andersen, R. K., Clausen, C., Jørgensen, F., Holst, B., Zaher, W. & Kassem, M., 2011.

Publikation: Konferencebidrag uden forlag/tidsskriftPosterForskning

64 Downloads (Pure)

CXCR7 signaling promotes breast cancer survival in response to mesenchymal stromal stem cell-derived factors

Al-Toub, M., Almohawes, M., Vishnubalaji, R., Alfayez, M., Aldahmash, A., Kassem, M. & Alajez, N. M., 2019, I : Cell Death Discovery. 5, 9 s., 87.

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Stem Cell Factor
Mesenchymal Stromal Cells
Neoplasms
Stromal Cells
Conditioned Culture Medium
126 Downloads (Pure)

Dasatinib and Doxorubicin Treatment of Sarcoma Initiating Cells: A Possible New Treatment Strategy

Aggerholm-Pedersen, N., Demouth, C., Safwat, A., Meldgaard, P., Kassem, M. & Sorensen, B. S., 2016, I : Stem Cells International. 2016, 8 s., 9601493.

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Sarcoma
Epidermal Growth Factor Receptor
Cell Survival
Cell Line
Transformed Cell Line