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2011

The best bone marrow stromal cell for therapy is … 'yellow'

Burns, J. S. & Kassem, M., 2011, I : Cytotherapy. 13, 6, s. 644-6 3 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Tumourigenicity and radiation resistance of mesenchymal stem cells

D'Andrea, F. P., Horsman, M. R., Kassem, M., Overgaard, J. & Safwat, A., 2011, I : Acta Oncologica. 51, 5, s. 669-79 11 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Mesenchymal Stromal Cells
Cell Line
Chromosome Mapping
Connective Tissue
Neoplasms

Wnt signalling mediates the cross-talk between bone marrow derived pre-adipocytic and pre-osteoblastic cell populations

Taipaleenmaki, H., Abdallah, B. M., Aldamash, A., Säämänen, A-M. & Kassem, M., 2011, I : Experimental Cell Research. 317, 6, s. 745-56 12 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Population
Chondrocytes
Osteoblasts
Mesenchymal Stromal Cells
Lipid Metabolism
2012

Bioactive implants: RNA interference as a tool to direct stem cell differentiation.

Dillschneider, P., Andersen, M. Ø., Kjems, J. & Kassem, M., 2012, I : Journal of Tissue Engineering and Regenerative Medicine. 6, S1, s. 292 1 s., 49.P05.

Publikation: Bidrag til tidsskriftKonferenceabstrakt i tidsskriftForskningpeer review

Controlling drug release spatially and temporally in scaffolds

Andersen, M. Ø., Nygaard, J. V., Le, D. Q. S., Burns, J., Raarup, M. K., Chen, M., Howard, K. A., Bünger, C., Kassem, M. & Kjems, J., 2012, I : Journal of Tissue Engineering and Regenerative Medicine. 6, S1

Publikation: Bidrag til tidsskriftKonferenceabstrakt i tidsskriftForskningpeer review

Derivation of Stromal (Skeletal, Mesenchymal) Stem-like cells from Human Embryonic Stem Cells

Mahmood, A., Harkness, L., Abdallah, B., El-Safadi, M., Al-Nbheen, M., Aldahmash, A. & Kassem, M., 2012, I : Stem Cells and Development. 21, 17, s. 3114-3124

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Mesenchymal Stromal Cells
Durapatite
Osteoblasts
Tissue Engineering
Human Embryonic Stem Cells

Encapsulated glucagon-like peptide-1-producing mesenchymal stem cells have a beneficial effect on failing pig hearts

Wright, E. J., Farrell, K. A., Malik, N., Kassem, M., Lewis, A. L., Wallrapp, C. & Holt, C. M., 2012, I : Stem Cells Translational Medicine. 1, 10, s. 759-69 11 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Mesenchymal Stromal Cells
Stem Cell Factor
Left Ventricular Function
Stromal Cells
Infarction

Fabrication and characterization of a rapid prototyped tissue engineering scaffold with embedded multicomponent matrix for controlled drug release

Chen, M., Le, D. Q., Hein, S., Li, P., Nygaard, J. V., Kassem, M., Kjems, J., Besenbacher, F. & Bünger, C., 2012, I : International Journal of Nanomedicine (Online). 7, s. 4285-97 13 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Tissue Scaffolds
Tissue Engineering
Scaffolds (biology)
Tissue engineering
Scaffolds

Glucose metabolite glyoxal induces senescence in telomerase-immortalized human mesenchymal stem cells

Larsen, S. A., Kassem, M. & Rattan, S. I., 2012, I : Chemistry Central Journal. 6, 1, s. 18

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Glyoxal
Telomerase
Metabolites
Stem cells
Glucose

Human stromal (mesenchymal) stem cells: basic biology and current clinical use for tissue regeneration

Aldahmash, A., Zaher, W., Al-Nbaheen, M. & Kassem, M., 2012, I : Annals of Saudi Medicine. 32, 1, s. 68-77 10 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Mesenchymal Stromal Cells
Cell Biology
Subcutaneous Fat
Bone Fractures
Mesoderm

Identification of Abnormal Stem Cells Using Raman Spectroscopy

Harkness, L., Novikov, S. M., Beermann, J., Bozhevolnyi, S. I. & Kassem, M., 2012, I : Stem Cells and Development. 21, 12, s. 2152-9 9 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Microscopy
Stromal Cells
Human Embryonic Stem Cells

Identification of a Predictive Molecular Signature For Ex Vivo Migration of Human Mesenchymal Stromal Cells

Andersen, R. K., Zaher, W., Larsen, K. H., Kassem, M. & Abdallah, B., 2012.

Publikation: Konferencebidrag uden forlag/tidsskriftKonferenceabstrakt til konferenceForskning

MECHANISMS IN ENDOCRINOLOGY MicroRNAs: Targets for enhancing osteoblast differentiation and bone formation

Taipaleenmäki, H., Bjerre, L., Chen, L., Kauppinen, S. & Kassem, M., 2012, I : European Journal of Endocrinology. 166, 3, s. 359-71 22 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Osteoblasts
MicroRNAs
Osteogenesis
Apoptosis

Mesenchymal Stem Cells: Application for Immunomodulation and Tissue Repair

Horwood, N. J., Dazzi, F., Zaher, W. & Kassem, M., 2012, Tissue and Cell Clinical Use: An Essential Guide . Warwick, R. M. & Brubaker, S. A. (red.). Wiley-Blackwell, s. 332-357

Publikation: Bidrag til bog/antologi/rapport/konference-proceedingBidrag til bog/antologiForskningpeer review

Mesenchymal Stromal Cells
Graft vs Host Disease
Mesoderm
Stromal Cells
Chondrocytes

Microcarrier-based expansion process for hMSCs with high vitality and undifferentiated characteristics

Elseberg, C. L., Leber, J., Salzig, D., Wallrapp, C., Kassem, M., Kraume, M. & Czermak, P., 2012, I : International Journal of Artificial Organs. 35, 2, s. 93-107 15 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Stem cells
Mesenchymal Stromal Cells
Glucose
Carrier concentration
Biomass

Mouse Embryonic Fibroblasts (MEF) Exhibit a Similar but not Identical Phenotype to Bone Marrow Stromal Stem Cells (BMSC)

Saeed, H., Taipaleenmäki, H., Aldahmash, A. M., Abdallah, B. M. & Kassem, M., 2012, I : Stem Cell Reviews. 8, 2, s. 318-28 11 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Mesenchymal Stromal Cells
Fibroblasts
Chondrocytes
Osteoblasts
Adipocytes

Procedures for Derivation and Characterisation of Human Embryonic Stem Cells from Odense, Denmark

Harkness, L. & Kassem, M., 2012, Human Embryonic Stem Cells Handbook: Methods in Molecular Biology. Turksen, K. (red.). Springer Science+Business Media, s. 33-51 (Methods in Molecular Medicine, Bind 873).

Publikation: Bidrag til bog/antologi/rapport/konference-proceedingBidrag til bog/antologiForskning

Denmark
Cell Line
Cell Biology
Flow Cytometry
Polymerase Chain Reaction

Sarcomas as a mise en abyme of mesenchymal stem cells: Exploiting interrelationships for cell mediated anticancer therapy

Burns, J. S., Safwat, A. A., Grisendi, G., Kassem, M. & Dominici, M., 2012, I : Cancer Letters. 325, 1, s. 1-10 10 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Mesenchymal Stromal Cells
Entosis
Sarcoma
Cell Fusion
Growth

Separate developmental programs for HLA-A and -B expression during diffenrentiation from embryonic stem cells to lymphocytes, adipocytes and osteocytes

Sabir, H. J., Isa, A., Nehlin, J., Qanie, D. W. M., Prokhorova, T., Kassem, M. & Barington, T., 31. maj 2012.

Publikation: Konferencebidrag uden forlag/tidsskriftKonferenceabstrakt til konferenceForskningpeer review

Serum levels of fetal antigen 1 in extreme nutritional States

Andries, A., Niemeier, A., Støving, R. K., Abdallah, B. M., Wolf, A-M., Hørder, K. & Kassem, M., 2012, I : International Scholarly Research Notices. 2012, s. 592648

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Morbid Obesity
Serum
Weights and Measures
Insulin
Weight Gain

Stable isotope labelling with amino acids in cell culture for human embryonic stem cell proteomic analysis

Harkness, L., Prokhorova, T. A., Kassem, M. & Blagoev, B., 2012, I : Methods in Molecular Biology. 873, s. 297-305 9 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskning

Isotope Labeling
Amino Acids
Proteins
Membranes
Human Embryonic Stem Cells

Temporal Profiling and Pulsed SILAC Labeling Identify Novel Secreted Proteins during ex vivo Osteoblast Differentiation of Human Stromal Stem Cells

Kristensen, L. P., Chen, L., Nielsen, M. O., Qanie, D. W., Kratchmarova, I., Kassem, M. & Andersen, J. S., 2012, I : Molecular and Cellular Proteomics. 11, 10, s. 989-1007 19 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Osteoblasts
Stromal Cells
Stem cells
Labeling
Proteins

The Cross-talk Between TGF-β1 and Dlk1 Mediates Early Chondrogenesis During Embryonic Endochondral Ossification

Taipaleenmaki, H., M, L., Chen, L., Larsen, K. H., Säämänen, A. M., Kassem, M. & Abdallah, B., 2012, I : Stem Cells. 30, 2, s. 304-13 10 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Chondrogenesis
Osteogenesis
Fibroblasts
Chondrocytes
Limb Buds

The Histone H2B Monoubiquitination Regulatory Pathway Is Required for Differentiation of Multipotent Stem Cells

Karpiuk, O., Najafova, Z., Kramer, F., Hennion, M., Galonska, C., König, A., Snaidero, N., Vogel, T., Shchebet, A., Begus-Nahrmann, Y., Kassem, M., Simons, M., Shcherbata, H., Beissbarth, T. & Johnsen, S. A., 2012, I : Molecular Cell. 46, 5, s. 705-13 9 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Mesenchymal Stromal Cells
Histones
Cell Differentiation
Cell Lineage
Ligases

Tumour microenvironment and radiation response in sarcomas originating from tumourigenic human mesenchymal stem cells

D'Andrea, F. P., Safwat, A. A., Burns, J. S., Kassem, M., Horsman, M. R. & Overgaard, J., 2012, I : International Journal of Radiation Biology. 88, 6, s. 457-65 9 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Mesenchymal Stromal Cells
Sarcoma
Clone Cells
Neoplasms
Intrinsic Factor
2013

Cell-based delivery of glucagon-like peptide-1 using encapsulated mesenchymal stem cells

Wallrapp, C., Thoenes, E., Thürmer, F., Jork, A., Kassem, M. & Geigle, P., 17. sep. 2013, I : Journal of Microencapsulation. 30, 4, s. 315-24

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Glucagon-Like Peptide 1
stem cells
Stem cells
Mesenchymal Stromal Cells
Peptides

Comparison between various biomarkers of senescence in bone marrow-derived stromal cells in vitro and ex-vivo

Nehlin, J., Kassem, M. & Frary, C., 6. sep. 2013.

Publikation: Konferencebidrag uden forlag/tidsskriftKonferenceabstrakt til konferenceForskningpeer review

Mesenchymal Stromal Cells
Galactosidases
Fixatives
Cell Aging
Poisons

Dual role of delta-like 1 homolog (DLK1) in skeletal muscle development and adult muscle regeneration

Andersen, D. C., Laborda, J., Baladron, V., Kassem, M., Sheikh, S. P. & Jensen, C. H., 2013, I : Development. 140, 18, s. 3743-3753

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Muscle Development
Skeletal Muscle
Muscles
Adipogenesis
Fats

Human Stromal (Mesenchymal) Stem Cells from Bone Marrow, Adipose Tissue and Skin Exhibit Differences in Molecular Phenotype and Differentiation Potential

Al-Nbaheen, M., Vishnubalaji, R., Ali, D., Bouslimi, A., Al-Jassir, F., Megges, M., Prigione, A., Adjaye, J., Kassem, M. & Aldahmash, A., 14. apr. 2013, I : Stem Cell Reviews. 9, 1, s. 32-43

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Mesenchymal Stromal Cells
Adipose Tissue
Stromal Cells
Skin
Adipocytes

Identification of differentiation-stage specific molecular markers for the osteoblastic phenotype

Twine, N., Chen, L., Wilkins, M. & Kassem, M., 7. okt. 2013. 1 s.

Publikation: Konferencebidrag uden forlag/tidsskriftPosterForskningpeer review

Mesenchymal Stromal Cells
Osteogenesis
RNA Sequence Analysis
Gene Ontology
Extracellular Matrix Proteins

Mesenchymal stem cells in oral reconstructive surgery: a systematic review of the literature

Jakobsen, C., Sørensen, J. A., Kassem, M. & Thygesen, T. H., 2013, I : Journal of Oral Rehabilitation. 40, 9, s. 693-706 14 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Mesenchymal Stromal Cells
Alveolar Ridge Augmentation
Clinical Trials
Third Molar
Tissue Engineering
487 Downloads (Pure)

Pleiotropic effects of cancer cells' secreted factors on human stromal (mesenchymal) stem cells

Al-toub, M., Almusa, A., Almajed, M., Al-Nbaheen, M., Kassem, M., Aldahmash, A. & Alajez, N., 2013, I : Stem Cell Research & Therapy. 4, 114, 19 s., 24405819.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Fil
Stem cells
Mesenchymal Stromal Cells
Tumors
Cells
Conditioned Culture Medium

Separate Developmental Programs for HLA-A and -B Cell Surface Expression during Differentiation from Embryonic Stem Cells to Lymphocytes, Adipocytes and Osteoblasts

Sabir, H. J., Nehlin, J. O., Qanie, D., Harkness, L., Prokhorova, T. A., Blagoev, B., Kassem, M., Isa, A. & Barington, T., 2013, I : P L o S One. 8, 1, s. e54366

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

HLA-A Antigens
Lymphocytes
osteoblasts
Osteoblasts
embryonic stem cells

Spatially controlled delivery of siRNAs to stem cells in implants generated by multi-component additive manufacturing

Andersen, M. Ø., Le, D. Q. S., Chen, M., Nygaard, J. V., Kassem, M., Bünger, C. & Kjems, J., 2013, I : Advanced Functional Materials. 23, 45, s. 5599-5607 9 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Sphingosine 1 Phosphate (S1P) Receptors 1 and 2 Coordinately Induce Osteoblast Migration Through S1P Activation of Complementary Kinase Pathways

Quint, P., Ruan, M., Pederson, L., Kassem, M., Westendorf, J. J., Khosla, S. & Oursler, M. J., 2013, I : Journal of Biological Chemistry. 288, s. 5398-5406

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Lysosphingolipid Receptors
Osteoblasts
Bone
Phosphotransferases
Chemical activation

Telomere dysfunction leads to changes in microglial numbers and morphology in a mouse model of premature aging. Glia, Volume 61, Issue Suppl 1, S157.

Khan, A. M., Babcock, A., Kassem, M. & Finsen, B., 2013.

Publikation: Konferencebidrag uden forlag/tidsskriftKonferenceabstrakt til konferenceForskningpeer review

Tools for the Validation of Genomes and Transcriptomes with Proteomics data

Pang, C. N. I., Aya, C., Tay, A., Deshpande, N. P., Kaakoush, N. O., Mitchell, H., Twine, N. A., Kassem, M. & Wilkins, M. R., 7. feb. 2013. 1 s.

Publikation: Konferencebidrag uden forlag/tidsskriftPosterForskningpeer review

proteomics
genome
genomics
peptide
mass spectrometry

Tumour-Derived Interleukin-1 Beta Induces Pro-inflammatory Response in Human Mesenchymal Stem Cells

Alajez, N. M., Al-toub, M., Almusa, A., Imajed, M. A., Kassem, M. & Aldahmash, A., 2013. 2 s.

Publikation: Konferencebidrag uden forlag/tidsskriftPosterForskningpeer review

Mesenchymal Stromal Cells
Interleukin-1beta
Neoplasms
Conditioned Culture Medium
Computational Biology
2014

Adult Stromal (Skeletal, Mesenchymal) Stem Cells: Advances Towards Clinical Applications.

Jafari, A., Harkness, L., Zaher, W. & Kassem, M., maj 2014, Adult Stem Cells, Stem Cell Biology and Regenerative Medicine. Turksen, K. (red.). Springer Science+Business Media, s. 359-373 15 s.

Publikation: Bidrag til bog/antologi/rapport/konference-proceedingBidrag til bog/antologiForskningpeer review

An update of human mesenchymal stem cell biology and their clinical uses

Zaher, W., Harkness, L., Jafari, A. & Kassem, M., maj 2014, I : Archives of Toxicology. 88, 5, s. 1069-82

Publikation: Bidrag til tidsskriftReviewForskningpeer review

Cytology
Stem cells
Mesenchymal Stromal Cells
Cell Biology
Stromal Cells

Clinical study on the therapeutic role of midodrine in non azotemic cirrhotic patients with tense ascites: a double-blind, placebo-controlled, randomized trial

Ali, A., Farid, S., AminAmin, M., Kassem, M. & Al-Garem, NN., 2014, I : Hepato-Gastroenterology. 61, 135, s. 1915-1924

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Midodrine
Randomized Controlled Trials
Placebos
Clinical Studies
Hepatorenal Syndrome

Concise review: bridging the gap: bone regeneration using skeletal stem cell-based strategies-where are we now?

Dawson, J. I., Kanczler, J., Kassem, M. & Oreffo, R. O. C., 2014, I : Stem Cells. 32, 1, s. 35-44 24115290.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Population
Cell Biology
Wounds and Injuries

Establishing quiescence in human bone marrow stem cells leads to enhanced osteoblast marker expression

Harkness, L., Rumman, M., Kassem, M. & Dahwan, J., 2014. 1 s.

Publikation: Konferencebidrag uden forlag/tidsskriftPosterForskningpeer review

Osteoblasts
Cell Cycle
Down-Regulation
Galactosidases
Cyclins

Establishing quiescence in human bone marrow stromal stem cells leads to enhanced osteoblast marker expression

Harkness, L., Rumman, M., Kassem, M. & Dhawan, J., 18. jun. 2014. 1 s.

Publikation: Konferencebidrag uden forlag/tidsskriftPosterForskningpeer review

Identification of differentiation-stage specific markers that define the ex vivo osteoblastic phenotype

Twine, N. A., Chen, L., Pang, C. N., Wilkins, M. R. & Kassem, M., 2014, I : Bone. 67, s. 23–32

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Mesenchymal Stromal Cells
RNA Sequence Analysis
Fibroblast Growth Factor 2
Osteoblasts
Cluster Analysis

Intracoronary Injection of CD34-Cells in Chronic Ischemic Heart Failure: 7 Years Follow-Up of the DanCell Study

Hansen, M., Nyby, S., Eifer Møller, J., Videbæk, L., Kassem, M., Barington, T., Thayssen, P. & Pyndt Diederichsen, A. C., 12. aug. 2014, I : Cardiology. 129, 2, s. 69-74

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Regression Analysis
Multivariate Analysis

Low/Negative Expression of PDGFR-α Identifies the Candidate Primary Mesenchymal Stromal Cells in Adult Human Bone Marrow

Li, H., Ghazanfari, R., Zacharaki, D., Ditzel, N., Isern, J., Ekblom, M., Méndez-Ferrer, S., Kassem, M. & Scheding, S., 9. dec. 2014, I : Stem Cell Reports. 3, 6, s. 965-974

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Mesenchymal Stromal Cells
Bone
Stem cells
Cells
Population

microRNA-320/RUNX2 axis regulates adipocytic differentiation of human mesenchymal (skeletal) stem cells

Hamam, D., Ali, D., Vishnubalaji, R., Hamam, R., Al-Nbaheen, M., Chen, L., Kassem, M., Aldahmash, A. & Alajez, N. M., 2014, I : Cell Death & Disease. 5, s. e1499

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Adipogenesis
MicroRNAs
Mesenchymal Stromal Cells
Gene Expression Profiling
Computational Biology

MicroRNA-34a inhibits osteoblast differentiation and in vivo bone formation of human stromal stem cells

Chen, L., Holmstrøm, K., Qiu, W., Ditzel, N., Shi, K., Hokland, L. & Kassem, M., 2014, I : Stem Cells. 32, 4, s. 902-912 11 s., 24307639.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Stromal Cells
Osteoblasts
MicroRNAs
Osteogenesis
Mesenchymal Stromal Cells

miR-141-3p inhibits human stromal (mesenchymal) stem cell proliferation and differentiation

Qiu, W. & Kassem, M., sep. 2014, I : BBA General Subjects. 1843, 9, s. 2114–2121

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

MicroRNAs
Mesenchymal Stromal Cells
Cell Differentiation
Cell Proliferation
Osteoblasts