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Udgivelsessår

  • 2019
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  • Martin Røssel Larsen
Bidrag til bog/antologi

Affinity proteomics for interactome and phosphoproteome screening in synaptosomes

Engholm-Keller, K., Bache, N., Rao, S. R., Wark, J. R., Larsen, M. R., Robinson, P. J. & Graham, M. E., sep. 2018, Synaptosomes. M. Murphy, K. (red.). Humana Press, Bind 141. s. 165-191 (Neuromethods, Bind 141).

Publikation: Bidrag til bog/antologi/rapport/konference-proceedingBidrag til bog/antologiForskningpeer review

Characterization of the phosphoproteome and sialoproteome in brain tissues by mass spectrometry

Ibáñez-Vea, M., Kempf, S. J. & Larsen, M. R., 2017, Current Proteomic Approaches Applied to Brain Function. Santamaría, E. & Fernández-Irigoyen, J. (red.). Humana Press, s. 191-206 (Neuromethods, Bind 127).

Publikation: Bidrag til bog/antologi/rapport/konference-proceedingBidrag til bog/antologiForskningpeer review

Kommentar/debat

Author Correction: Snake Venom Extracellular vesicles (SVEVs) reveal wide molecular and functional proteome diversity

Carregari, V. C., Rosa-Fernandes, L., Baldasso, P., Bydlowski, S. P., Marangoni, S., Larsen, M. R. & Palmisano, G., 23. okt. 2018, I : Scientific Reports. 8, 1 s., 15908.

Publikation: Bidrag til tidsskriftKommentar/debatForskningpeer review

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Konferenceabstrakt i tidsskrift

Cellular and molecular abnormalities in brain organoids derived from autistic patients

Ilieva, M., Kamand, M., Forsberg, S. L., Larsen, M. R. & Tanja, M., dec. 2019, I : European Neuropsychopharmacology. 29, Suppl. 6, s. S359-S360 P.510.

Publikation: Bidrag til tidsskriftKonferenceabstrakt i tidsskriftForskningpeer review

Identifying the Angiotensin AT2-Receptor Coupled Phosphoproteome in Human Aortic Endothelial Cells by Time-Resolved, Quantitative Phosphoproteomics

Peluso, A. A. B., Kempf, S., Brega, T. V., Bader, M., Larsen, M. R., Santos, R. SA. & Steckelings, U. M., 2018, I : Hypertension. 72, Suppl. 1, P240.

Publikation: Bidrag til tidsskriftKonferenceabstrakt i tidsskriftForskningpeer review

Phosphoproteomic Analysis of Murine Hepatocytes Reveals Novel Targets of Hepatic Glucagon Action

Boland, M. L., Nawrocki, A., Mather, K., Jain, M., Jermutus, L., Larsen, M. R., Rhodes, C. J. & Trevaskis, J., okt. 2018, I : Hepatology. 68, Suppl. 1, s. 1018A 1 s., 1790.

Publikation: Bidrag til tidsskriftKonferenceabstrakt i tidsskriftForskning

Patent

GLYCOSYLATED POLYPEPTIDES ORIGINATING FROM ENTEROTOXIGENIC ESCHERICHIA COLI (ETEC): -

Bidragets oversatte titel: -: -Boysen, A., Møller-Jensen, J., Palmisano, G. & Larsen, M. R., 15. okt. 2015, IPC nr. A61K 39/108 (2006.01), Patentnr. WO/2015/154783, Prioritetsdato 10. apr. 2014, Prioritetsnr. PCT/DK2015/050089

Publikation: Patent

GLYCOSYLATED YGHJ POLYPEPTIDES FROM ENTEROTOXIGENIC ESCHERICHIA COLI (ETEC)

Boysen, A., Møller-Jensen, J., Palmisano, G. & Larsen, M. R., 13. apr. 2017, Patentnr. WO2017059864 (A1), 13. apr. 2017, Prioritetsdato 6. okt. 2015, Prioritetsnr. EP20150188608

Publikation: Patent

Poster

"Highly increased expression of astrocytic cytokine in neocortex of Alzheimer’s patients investigated by proteomics"

Thygesen, C., Kempf, S., Metaxas, A., Darvesh, S., Larsen, M. R. & Finsen, B., 2017.

Publikation: Konferencebidrag uden forlag/tidsskriftPosterForskningpeer review

Review

Characterizing disease-associated changes in post-translational modifications by mass spectrometry

Thygesen, C., Boll, I., Finsen, B., Modzel, M. & Larsen, M. R., 2018, I : Expert Review of Proteomics. 15, 3, s. 245-258

Publikation: Bidrag til tidsskriftReviewForskningpeer review

Proteomic signatures of neuroinflammation in Alzheimer's disease, multiple sclerosis and ischemic stroke

Thygesen, C., Larsen, M. R. & Finsen, B., jul. 2019, I : Expert Review of Proteomics. 16, 7, s. 601-611

Publikation: Bidrag til tidsskriftReviewForskningpeer review

Understanding Alzheimer's disease by global quantification of protein phosphorylation and sialylated N-linked glycosylation profiles: A chance for new biomarkers in neuroproteomics?

Lassen, P. S., Thygesen, C., Larsen, M. R. & Kempf, S. J., 2017, I : Journal of Proteomics. 161, May, s. 11-25

Publikation: Bidrag til tidsskriftReviewForskningpeer review

Tidsskriftartikel

Ageing and amyloidosis underlie the molecular and pathological alterations of tau in a mouse model of familial Alzheimer’s disease

Metaxas, A., Thygesen, C., Kempf, S. J., Anzalone, M., Vaitheeswaran, R., Petersen, S., Landau, A. M., Audrain, H., Teeling, J. L., Darvesh, S., Brooks, D. J., Larsen, M. R. & Finsen, B., 31. okt. 2019, I : Scientific Reports. 9, 1, 15 s., 15758.

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Alterations in the Cerebral Microvascular Proteome Expression Profile After Transient Global Cerebral Ischemia in Rat

Spray, S., Johansson, S. E., Edwards, A. V. G., Larsen, M. R., Radziwon-Balicka, A., Povlsen, G. K. & Edvinsson, L., 2017, I : Journal of Molecular Neuroscience. 61, 3, s. 396–411

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A Systems-level Characterization of the Differentiation of Human Embryonic Stem Cells into Mesenchymal Stem Cells

Billing, A. M., Dib, S. S., Bhagwat, A. M., da Silva, I. T., Drummond, R. D., Hayat, S., Al-Mismar, R., Ben-Hamidane, H., Goswami, N., Engholm-Keller, K., Larsen, M. R., Suhre, K., Rafii, A. & Graumann, J., 1. okt. 2019, I : Molecular and Cellular Proteomics. 18, 10, s. 1950-1966

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A Targeted LC-MS Strategy for Low-Abundant HLA Class-I-Presented Peptide Detection Identifies Novel Human Papillomavirus T-Cell Epitopes

Blatnik, R., Mohan, N., Bonsack, M., Falkenby, L. G., Hoppe, S., Josef, K., Steinbach, A., Becker, S., Nadler, W. M., Rucevic, M., Larsen, M. R., Salek, M. & Riemer, A. B., jun. 2018, I : Proteomics. 18, 11, 9 s., 1700390.

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Automated N-glycan profiling of a mutant Trypanosoma rangeli sialidase expressed in Pichia pastoris, using tandem mass spectrometry and bioinformatics

Li, H., Rasmussen, M. I., Larsen, M. R., Guo, Y., Jers, C., Palmisano, G., Mikkelsen, J. D. & Kirpekar, F., dec. 2015, I : Glycobiology. 25, 12, s. 1350-1361

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Characterization of human neural differentiation from pluripotent stem cells using proteomics/PTMomics: current state-of-the-art and challenges

Braga, M. N. D. M., Meyer, M., Zeng, X. & Larsen, M. R., 2015, I : Proteomics. 15, 4, s. 656-74

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Characterization of Macrophage Endogenous S-Nitrosoproteome Using a Cysteine-Specific Phosphonate Adaptable Tag in Combination with TiO2 Chromatography

Ibáñez-Vea, M., Huang, H., Martínez De Morentin, X., Pérez, E., Gato, M., Zuazo, M., Arasanz, H., Fernández-Irigoyen, J., Santamaría, E., Fernandez-Hinojal, G., Larsen, M. R., Escors, D. & Kochan, G., 2018, I : Journal of Proteome Research. 17, 3, s. 1172-1182

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Comprehensive glycoprofiling of the epimastigote and trypomastigote stages of Trypanosoma cruzi

Alves, M. J. M., Kawahara, R., Viner, R., Colli, W., Mattos, E. C., Thaysen-Andersen, M., Larsen, M. R. & Palmisano, G., 16. jan. 2017, I : Journal of Proteomics. 151, s. 182-192

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Convergent Akt activation drives acquired EGFR inhibitor resistance in lung cancer

Jacobsen, K., Bertran-Alamillo, J., Molina, M. A., Teixidó, C., Karachaliou, N., Pedersen, M. H., Castellví, J., Garzón, M., Codony-Servat, C., Codony-Servat, J., Giménez-Capitán, A., Drozdowskyj, A., Viteri, S., Larsen, M. R., Lassen, U., Felip, E., Bivona, T. G., Ditzel, H. J. & Rosell, R., 1. dec. 2017, I : Nature Communications. 8, 14 s., 410.

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Development of a Neo-Epitope Specific Assay for Serological Assessment of Type VII Collagen Turnover and Its Relevance in Fibroproliferative Disorders

Sand, J. M. B., Lamy, P., Juhl, P., Siebuhr, A. S., Iversen, L. V., Nawrocki, A., Larsen, M. R., Domsic, R. T., Franchimont, N., Chavez, J., Karsdal, M. A. & Leeming, D. J., 2018, I : ASSAY and Drug Development Technologies. 16, 2, s. 123-131

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Development of a Trypanosoma cruzi strain typing assay using MS2 peptide spectral libraries (Tc-STAMS2)

de Oliveira, G. S., Kawahara, R., Rosa-Fernandes, L., Mule, S. N., Avila, C. C., Teixeira, M. M. G., Larsen, M. R. & Palmisano, G., 2018, I : PLOS Neglected Tropical Diseases . 12, 4, e0006351.

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Distinct urinary glycoprotein signatures in prostate cancer patients

Kawahara, R., Ortega, F., Rosa-Fernandes, L., Guimarães, V., Quina, D., Nahas, W., Schwämmle, V., Srougi, M., Leite, K. R. M., Thaysen-Andersen, M., Larsen, M. R. & Palmisano, G., 4. sep. 2018, I : Oncotarget. 9, 69, s. 33077-33097

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Diverse protein profiles in CNS myeloid cells and CNS tissue from lipopolysaccharide- and vehicle-injected APPSWE/PS1ΔE9 transgenic mice implicate cathepsin Z in alzheimer’s disease

Thygesen, C., Ilkjær, L., Kempf, S. J., Hemdrup, A. L., von Linstow, C. U., Babcock, A. A., Darvesh, S., Larsen, M. R. & Finsen, B., nov. 2018, I : Frontiers in cellular neuroscience. 12, 21 s., 397.

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Dynamic Changes in the Protein Localization in the Nuclear Environment in Pancreatic β-Cell after Brief Glucose Stimulation

Kang, T., Jensen, P., Solovyeva, V., Brewer, J. R. & Larsen, M. R., 6. apr. 2018, I : Journal of Proteome Research. 17, 4, s. 1664–1676

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Elucidation of altered pathways in tumor-initiating cells of triple-negative breast cancer: A useful cell model system for drug screening

Christensen, A. G., Ehmsen, S., Terp, M. G., Batra, R., Alcaraz, N., Baumbach, J., Noer, J. B., Moreira, J. M. A., Leth-Larsen, R., Larsen, M. R. & Ditzel, H. J., aug. 2017, I : Stem Cells. 35, 8, s. 1898–1912

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Experimental demyelination and axonal loss are reduced in MicroRNA-146a deficient mice

Martin, N. A., Molnar, V., Szilagyi, G. T., Elkjaer, M. L., Nawrocki, A., Okarmus, J., Wlodarczyk, A., Thygesen, E. K., Palkovits, M., Gallyas, F., Larsen, M. R., Lassmann, H., Benedikz, E., Owens, T., Svenningsen, A. F. & Illes, Z., 2018, I : Frontiers in Immunology. 9, 14 s., 490.

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Extracellular vesicles with altered tetraspanin CD9 and CD151 levels confer increased prostate cell motility and invasion

Brzozowski, J. S., Bond, D. R., Jankowski, H., Goldie, B. J., Burchell, R., Naudin, C., Smith, N. D., Scarlett, C. J., Larsen, M. R., Dun, M. D., Skelding, K. A. & Weidenhofer, J., 11. jun. 2018, I : Scientific Reports. 8, 13 s., 8822.

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First-trimester proteomic profiling identifies novel predictors of gestational diabetes mellitus

Ravnsborg, T., Svaneklink, S., Andersen, L. L. T., Larsen, M. R., Jensen, D. M. & Overgaard, M., 27. mar. 2019, I : PLOS ONE. 14, 3, 13 s., e0214457.

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How many human proteoforms are there?

Aebersold, R., Agar, J. N., Amster, I. J., Baker, M. S., Bertozzi, C. R., Boja, E. S., Costello, C. E., Cravatt, B. F., Fenselau, C., Garcia, B. A., Ge, Y., Gunawardena, J., Hendrickson, R. C., Hergenrother, P. J., Huber, C. G., Ivanov, A. R., Jensen, O. N., Jewett, M. C., Kelleher, N. L., Kiessling, L. L. & 33 flere, Krogan, N. J., Larsen, M. R., Loo, J. A., Ogorzalek Loo, R. R., Lundberg, E., MacCoss, M. J., Mallick, P., Mootha, V. K., Mrksich, M., Muir, T. W., Patrie, S. M., Pesavento, J. J., Pitteri, S. J., Rodriguez, H., Saghatelian, A., Sandoval, W., Schlüter, H., Sechi, S., Slavoff, S. A., Smith, L. M., Snyder, M. P., Thomas, P. M., Uhlén, M., Van Eyk, J. E., Vidal, M., Walt, D. R., White, F. M., Williams, E. R., Wohlschlager, T., Wysocki, V. H., Yates, N. A., Young, N. L. & Zhang, B., 14. feb. 2018, I : Nature Chemical Biology. 14, 3, s. 206-214

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Important options available - from start to finish -for translating proteomics results to clinical chemistry

Heegaard, N. H. H., Ostergaard, O., Bahl, J. M. C., Overgaard, M., Beck, H. C., Rasmussen, L. M. & Larsen, M. R., 2015, I : Proteomics - Clinical Applications. 9, 1-2, s. 235-252

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Integrated proteomics reveals apoptosis-related mechanisms associated with placental malaria

Kawahara, R., Rosa-Fernandes, L., Dos Santos, A. F., Bandeira, C. L., Dombrowski, J. G., Souza, R. M., da Fonseca, M. P., Festuccia, W. T., Labriola, L., Larsen, M. R., Marinho, C. R. F. & Palmisano, G., 1. feb. 2019, I : Molecular and Cellular Proteomics. 18, 2, s. 182-199

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Novel DNA coding regions and protein arginylation reveal unexplored T. cruzi proteome and PTMs

de Oliveira, G. S., Kawahara, R., Rosa-Fernandes, L., Avila, C. C., Larsen, M. R., Pereira Alves, J. M. & Palmisano, G., 2017, I : International Journal of Mass Spectrometry. 418, s. 51-66

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NS1 codon usage adaptation to humans in pandemic Zika virus

Freire, C. C. D. M., Palmisano, G., Braconi, C. T., Cugola, F. R., Russo, F. B., Beltrão-Braga, P. C. B., Iamarino, A., de Lima Neto, D. F., Sall, A. A., Rosa-Fernandes, L., Larsen, M. R. & Zanotto, P. M. D. A., 2018, I : Memórias do Instituto Oswaldo Cruz. 113, 5, e170385.

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Omics-based approach reveals complement-mediated inflammation in chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS)

Blaabjerg, M., Hemdrup, A. L., Drici, L., Ruprecht, K., Garred, P., Höftberger, R., Kristensen, B. W., Kondziella, D., Sejbaek, T., Hansen, S. W., Nielsen, H. H., Jensen, P., Meyer, M., Paul, F., Lassmann, H., Larsen, M. R. & Illes, Z., 2018, I : Frontiers in Immunology. 9, 13 s., 741.

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Optimization of calmodulin-affinity chromatography for brain and organelles

Kulej, K., Sidoli, S., Palmisano, G., Edwards, A. V. G., Robinson, P. J. & Larsen, M. R., 2015, I : EuPA Open Proteonomics. 8, s. 55-67

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Orthologous proteins of experimental de- and remyelination are differentially regulated in the CSF proteome of multiple sclerosis subtypes

Martin, N. A., Nawrocki, A., Molnar, V., Elkjaer, M. L., Thygesen, E. K., Palkovits, M., Acs, P., Sejbaek, T., Nielsen, H. H., Hegedus, Z., Sellebjerg, F., Molnar, T., Barbosa, E. G. V., Alcaraz, N., Gallyas, F., Svenningsen, A. F., Baumbach, J., Lassmann, H., Larsen, M. R. & Illes, Z., 2018, I : PLOS ONE. 13, 8, s. 1-26 e0202530.

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PARK2 Mutation Causes Metabolic Disturbances and Impaired Survival of Human iPSC-Derived Neurons

Bogetofte Thomasen, H., Jensen, P., Ryding, M. A. J. G., Schmidt, S. I., Okarmus, J., Ritter, L., Worm, C. S., Hohnholt, M., Azevedo, C., Roybon, L., Bak, L. K., Waagepetersen, H. S., Ryan, B. J., Wade-Martins, R., Larsen, M. R. & Meyer, M., 5. jul. 2019, I : Frontiers in Cellular Neuroscience. 13, 14 s., 297.

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Perturbations in RhoA signalling cause altered migration and impaired neuritogenesis in human iPSC-derived neural cells with PARK2 mutation

Bogetofte, H., Jensen, P., Okarmus, J., Schmidt, S. I., Agger, M., Ryding, M., Nørregaard, P., Fenger, C., Zeng, X., Graakjær, J., Ryan, B. J., Wade-Martins, R., Larsen, M. R. & Meyer, M., dec. 2019, I : Neurobiology of Disease. 132, 14 s., 104581.

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Proteomic Analysis of Restored Insulin Production and Trafficking in Obese Diabetic Mouse Pancreatic Islets following Euglycemia

Kang, T., Boland, B. B., Alarcon, C., Grimsby, J. S., Rhodes, C. J. & Larsen, M. R., 6. sep. 2019, I : Journal of Proteome Research. 18, 9, s. 3245-3258

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Proteomic Expression Changes in Large Cerebral Arteries After Experimental Subarachnoid Hemorrhage in Rat Are Regulated by the MEK-ERK1/2 Pathway

Müller, A. H., Edwards, A. V. G., Larsen, M. R., Nielsen, J., Warfvinge, K., Povlsen, G. K. & Edvinsson, L., 2017, I : Journal of Molecular Neuroscience. 62, 3-4, s. 380-394

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Proteomic profiling of mouse epididymosomes reveals their contributions to post-testicular sperm maturation

Nixon, B., De Iuliis, G. N., Hart, H. M., Zhou, W., Mathe, A., Bernstein, I., Anderson, A. L., Stanger, S. J., Skerrett-Byrne, D. A., Jamaluddin, M. F. B., Almazi, J. G., Bromfield, E. G., Larsen, M. R. & Dun, M. D., 15. mar. 2019, I : Molecular and Cellular Proteomics. 18, Suppl. 1, s. S91-S108

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Proteomics insights into the responses of Saccharomyces cerevisiae during mixed-culture alcoholic fermentation with Lachancea thermotolerans

Peng, C., Andersen, B., Arshid, S., Larsen, M. R., Albergaria, H., Lametsch, R. & Arneborg, N., sep. 2019, I : FEMS Microbiology Ecology. 95, 9, 16 s.

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Proteotranscriptomic profiling of 231-BR breast cancer cells: Identification of potential biomarkers and therapeutic targets for brain metastasis

Dun, M. D., Chalkley, R. J., Faulkner, S., Keene, S., Avery-Kiejda, K. A., Scott, R. J., Falkenby, L. G., Cairns, M. J., Larsen, M. R., Bradshaw, R. A. & Hondermarck, H., 2015, I : Molecular and Cellular Proteomics. 14, 9, s. 2316-2330

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Quantitative Proteome Analysis Reveals Increased Content of Basement Membrane Proteins in Arteries from Patients with Type 2 Diabetes and Lower Levels among Metformin Users

Rørdam Preil, S., Kristensen, L. P., Beck, H. C., Jensen, P. S., Nielsen, P. S., Steiniche, T., Bjørling-Poulsen, M., Larsen, M. R., Hansen, M. L. & Rasmussen, L. M., 14. sep. 2015, I : Circulation: Cardiovascular Genetics. 8, s. 727-35

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Quantitative proteomics analysis of platelet-derived microparticles reveals distinct protein signatures when stimulated by different physiological agonists

Milioli, M., Vea, M. I., Sidoli, S., Palmisano, G., Careri, M. & Larsen, M. R., 2015, I : Journal of Proteomics. 121, s. 56-66

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