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2018
133 Downloads (Pure)

Association of miR-548c-5p, miR-7-5p, miR-210-3p, miR-128-3p with recurrence in systemically untreated breast cancer

Block, I., Burton, M., Sørensen, K. P., Andersen, L., Larsen, M. J., Bak, M., Cold, S., Thomassen, M., Tan, Q. & Kruse, T. A., 6. feb. 2018, I : OncoTarget. 9, 10, s. 9030-9042

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2019

Genomisk medicin og kunstig intelligens

Kruse, T. A., Larsen, M. J., Tan, Q., Andersen, L. & Thomassen, M., 1. apr. 2019, I : Ugeskrift for Laeger. 181, 7A, V02190085.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Medicine
Datasets
Clinical Decision-Making
2017

A case-only genome-wide association study for assessing gene-sex interaction in Allergic rhinitis

Mohammadnejad, A., Brasch-Andersen, C., Haagerup, A., Vestbo, J., Baumbach, J. & Tan, Q., aug. 2017.

Publikation: Konferencebidrag uden forlag/tidsskriftPosterForskningpeer review

Genome-Wide Association Study
Single Nucleotide Polymorphism
Chromosomes, Human, Pair 12
Posters
Chromosomes, Human, Pair 5

Efficient Management of High-Throughput Screening Libraries with SAVANAH

List, M., Elnegaard, M. P., Schmidt, S., Christiansen, H., Tan, Q., Mollenhauer, J. & Baumbach, J., 2017, I : Journal of Biomolecular Screening. 22, 2, s. 196-202

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Libraries
Screening
Throughput
Assays
Explosions
2018
129 Downloads (Pure)

Heritability and Genome-Wide Association Analyses of Serum Uric Acid in Middle and Old-Aged Chinese Twins

Wang, W., Zhang, D., Xu, C., Wu, Y., Duan, H., Li, S. & Tan, Q., 6. mar. 2018, I : Frontiers in Endocrinology. 9, MAR, 12 s., 75.

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Genome-Wide Association Study
Uric Acid
Serum
Single Nucleotide Polymorphism
Chromosomes, Human, Pair 14
2019

Network based analysis of microarray gene expression profiles in response to electroacupuncture

Mohammadnejad, A., Li, S., Duan, H. & Tan, Q., 4. sep. 2019, I : Journal of Traditional and Complementary Medicine. 7 s.

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Electroacupuncture
Transcriptome
Periaqueductal Gray
Gene Ontology
2017

Association of X chromosome-linked DNA-methylation with mortality in the elderly.

Lund, J., Baumbach, J. & Tan, Q., jun. 2017.

Publikation: Konferencebidrag uden forlag/tidsskriftPosterForskningpeer review

DNA Methylation
Epigenomics
Proportional Hazards Models
Sample Size
Epidemiologic Studies

Enriched power of case-only design in detecting gene-gene interaction using disease concordant twins

Li, W., Vandin, F., Baumbach, J. & Tan, Q., 22. jun. 2017.

Publikation: Konferencebidrag uden forlag/tidsskriftPosterForskningpeer review

Genes
Computer simulation
2018

Surfactant protein-D, a potential mediator of inflammation in axial spondyloarthritis

Munk, H. L., Fakih, D., Christiansen, L., Tan, Q., Christensen, A. F., Ejstrup, L., Loft, A. G., Junker, K., Kyvik, K. O., Jounblat, R., Holmskov, U., Sorensen, G. L. & Junker, P., 1. okt. 2018, I : Rheumatology (Oxford, England). 57, 10, s. 1861–1865

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Pulmonary Surfactant-Associated Protein D
Molecular Weight
Serum
Single Nucleotide Polymorphism
Smoking
2019

Impact of obesity and physical inactivity on the long-term change in grip strength among middle-aged and older European adults

Wang, T., Feng, W., Li, S., Tan, Q., Zhang, D. & Wu, Y., 1. jul. 2019, I : Journal of Epidemiology & Community Health. 73, 7, s. 619-624

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Exercise
Retirement
Health Surveys
Surveys and Questionnaires
2017

Identification, replication and characterization of epigenetic remodelling in the aging genome

Li, S., Christiansen, L., Christensen, K., Kruse, T. A., Redmond, P., Marioni, R. E., Deary, L. J. & Tan, Q., 2017. 1 s.

Publikation: Konferencebidrag uden forlag/tidsskriftPosterForskningpeer review

Epigenomics
CpG Islands
DNA
DNA Methylation
2018

DNA methylation linked to all-cause mortality in older people: An epigenome-wide association study.

Lund, J., Baumbach, J. & Tan, Q., mar. 2018.

Publikation: Konferencebidrag uden forlag/tidsskriftPosterForskningpeer review

DNA Methylation
G-Protein-Coupled Receptors
Proportional Hazards Models
Epigenomics
Skeleton

Circulating, Cell-Free Micro-RNA Profiles Reflect Discordant Development of Dementia in Monozygotic Twins

Mengel-From, J., Rønne, M. E., Carlsen, A. L., Skogstrand, K., Larsen, L. A., Tan, Q., Christiansen, L., Christensen, K. & Heegaard, N. H. H., 1. jan. 2018, I : Journal of Alzheimer's disease : JAD. 63, 2, s. 591-601

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Monozygotic Twins
MicroRNAs
Immunoassay
Lipoproteins
Longitudinal Studies
2017
66 Downloads (Pure)

Genetic and Environmental Influences on Correlations Between Hearing and Cognitive Functions in Middle and Older Chinese Twins

Xu, C., Zhang, D., Tian, X., Duan, H., Wu, Y., Pang, Z., Li, S. & Tan, Q., 2017, I : Twin Research and Human Genetics. 20, 5, s. 374-379

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Cognition
Hearing
Twin Studies
2018
100 Downloads (Pure)

Differential effect of surgical manipulation on gene expression in normal breast tissue and breast tumor tissue

Pedersen, I. S., Thomassen, M., Tan, Q., Kruse, T. A., Thorlacius-Ussing, O., Garne, J. P. & Krarup, H. B., 16. nov. 2018, I : Molecular Medicine. 24, 8 s., 57.

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Neoplasms
Gene Expression Profiling
Transcriptome
Freezing
140 Downloads (Pure)

Sex Differences in Genetic Associations With Longevity

Zeng, Y., Nie, C., Min, J., Chen, H., Liu, X., Ye, R., Chen, Z., Bai, C., Xie, E., Yin, Z., Lv, Y., Lu, J., Li, J., Ni, T., Bolund, L., Land, K. C., Yashin, A. I., O'Rand, A. M., Sun, L., Yang, Z. & 22 flere, Tao, W., Gurinovich, A., Franceschi, C., Xie, J., Gu, J., Hou, Y., Liu, X., Xu, X., Robine, J-M., Deelen, J., Sebastiani, P., Slagboom, E., Perls, T. T., Hauser, E. R., Gottschalk, W., Tan, Q., Christensen, K., Shi, X., Lutz, M., Tian, X-L., Yang, H. & Vaupel, J. W., aug. 2018, I : JAMA Network Open. 1, 4, 15 s., 1670.

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Sex Characteristics
Genome-Wide Association Study
Delivery of Health Care
Tryptophan
Case-Control Studies
2016

Robust and on-line multi-omics de novo pathway enrichment with KeyPathwayMiner

Alcaraz, N., List, M., Dissing-Hansen, M., Rehmsmeier, M., Tan, Q., Mollenhauer, J., Ditzel, H. & Baumbach, J., 2016.

Publikation: Konferencebidrag uden forlag/tidsskriftPosterForskningpeer review

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2017

A genome-wide association study of cognitive function in Chinese adult twins

Xu, C., Zhang, D., Wu, Y., Tian, X., Pang, Z., Li, S. & Tan, Q., 1. okt. 2017, I : Biogerontology. 18, 5, s. 811–819

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Genome-Wide Association Study
Cognition
Single Nucleotide Polymorphism
Dizygotic Twins
Metabolic Diseases
2019
41 Downloads (Pure)

Age‐dependent DNA methylation patterns on the Y chromosome in elderly males

Lund, J. B., Li, S., Christensen, K., Mengel-From, J., Thinggaard, M. S., Marioni, R. E., Starr, J., Pattie, A., Deary, I. J., Baumbach, J. & Tan, Q., 2019, I : Aging Cell. 8 s.

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DNA Methylation
Epigenomics
Sex Characteristics
2018

Adenoid cystic carcinomas of the salivary gland, lacrimal gland, and breast are morphologically and genetically similar but have distinct microRNA expression profiles

Andreasen, S., Tan, Q., Agander, T. K., Steiner, P., Bjørndal, K., Høgdall, E., Larsen, S. R., Erentaite, D., Olsen, C. H., Ulhøi, B. P., von Holstein, S. L., Wessel, I., Heegaard, S. & Homøe, P., aug. 2018, I : Modern Pathology. 31, 8, s. 1211–1225

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Lacrimal Apparatus
Adenoid Cystic Carcinoma
MicroRNAs
Neoplasms
Glandular and Epithelial Neoplasms
112 Downloads (Pure)

Epigenetic signature of preterm birth in adult twins

Tan, Q., Li, S., Frost, M., Nygaard, M., Soerensen, M., Larsen, M., Christensen, K. & Christiansen, L., 2018, I : Clinical Epigenetics. 10, 10 s., 87.

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Premature Birth
Epigenomics
Health
Chromosomes, Human, Pair 5
Chromosomes, Human, Pair 3
2019
126 Downloads (Pure)

Epigenome-wide association study of depression symptomatology in elderly monozygotic twins

Starnawska, A., Tan, Q., Sørensen, M., McGue, M., Mors, O., Børglum, A. D., Christensen, K., Nyegaard, M. & Christiansen, L., 2. sep. 2019, I : Translational Psychiatry. 9, 1, 14 s., 214.

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Monozygotic Twins
Depression
DNA Methylation
Epigenomics
Flow Cytometry
Twin Studies
2017
131 Downloads (Pure)

Genetic and Environmental Basis in Phenotype Correlation Between Physical Function and Cognition in Aging Chinese Twins

Xu, C., Zhang, D., Tian, X., Wu, Y., Pang, Z., Li, S. & Tan, Q., 2017, I : Twin Research and Human Genetics. 20, 1, s. 60-65

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Cognition
Visual Acuity
Forced Expiratory Volume
Population Genetics
Lung
2018

Online interactive microbial classification and geospatial distributional analysis using BioAtlas

Lund, J., Tan, Q. & Baumbach, J., 2018, Data Mining for Systems Biology: Methods and Protocols. Mamitsuka, H. (red.). New York: Humana Press, Bind 1807. s. 21-35 (Methods in Molecular Biology, Bind 1807).

Publikation: Bidrag til bog/antologi/rapport/konference-proceedingBidrag til bog/antologiForskningpeer review

Databases
rRNA Genes
16S Ribosomal RNA
Metagenomics
Datasets
93 Downloads (Pure)
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Long Noncoding RNA
Lymph Nodes
Human Genome
2018
142 Downloads (Pure)

DNA Methylation and All-Cause Mortality in Middle-Aged and Elderly Danish Twins

Svane, A. M., Soerensen, M., Lund, J., Tan, Q., Jylhävä, J., Wang, Y., Pedersen, N. L., Hägg, S., Debrabant, B., Deary, I. J., Christensen, K., Christiansen, L. & Hjelmborg, J. B., 8. feb. 2018, I : Genes. 9, 2, 15 s., 78.

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DNA Methylation
Twin Studies
Monozygotic Twins
Population
2015

Power advantage of concordant twin design in genome-wide association studies

Li, W., Vandin, F. & Tan, Q., okt. 2015.

Publikation: Konferencebidrag uden forlag/tidsskriftPosterForskningpeer review

2018

On the power of epigenome-wide association studies using a disease-discordant twin design

Li, W., Christiansen, L., Hjelmborg, J. V. B., Baumbach, J. & Tan, Q., 1. dec. 2018, I : Bioinformatics. 34, 23, s. 4073–4078

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Diseases in Twins
Monozygotic Twins
DNA Methylation
Computational Biology
Epigenomics
2016
103 Downloads (Pure)

Change in Depression Symptomatology and Cognitive Function in Twins: A 10-Year Follow-Up Study

Petersen, I., McGue, M., Tan, Q., Christensen, K. & Christiansen, L., apr. 2016, I : Twin Research and Human Genetics. 19, 2, s. 104-111

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antineoplaston A10
Cognition
Depression
Affective Symptoms
Twin Studies
2017

The gene expression and immunohistochemical time-course of diphenylcyclopropenone induced contact allergy in healthy humans following repeated epicutaneous challenges

Mose, K. F., Burton, M., Thomassen, M., Andersen, F., Kruse, T. A., Tan, Q., Skov, L., Almose Røpke, M., Litman, T., Clemmensen, O., Kristensen, B. W., S. Friedmann, P. & Andersen, K. E., 2017, I : Experimental Dermatology. 26, 10, s. 926–933

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Hypersensitivity
diphenylcyclopropenone
Polymerase Chain Reaction
Interleukin-17
Gene Expression Profiling
2015

Epigenetics and Bone Status: a Twin Study with Emphasis on the FOXO3A Region

Sørensen, M., Erbs, L., Nielsen, M. F. M., Tan, Q., Christensen, K. & Christiansen, L., nov. 2015, I : Gerontologist. 55, Suppl. 2, s. 62-63

Publikation: Bidrag til tidsskriftKonferenceabstrakt i tidsskriftForskning

Twin Studies
Epigenomics
Bone Density
Cytidine Triphosphate
CpG Islands
2016
106 Downloads (Pure)

Copy number variation associates with mortality in long-lived individuals: a genome-wide assessment

Nygaard, M., Debrabant, B., Tan, Q., Deelen, J., Andersen-Ranberg, K., de Craen, A. J. M., Beekman, M., Jeune, B., Slagboom, P. E., Christensen, K. & Christiansen, L., feb. 2016, I : Aging Cell. 15, 1, s. 49-55

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Human Genome
Population
95 Downloads (Pure)

Genetic and Environmental Regulation on Longitudinal Change of Metabolic Phenotypes in Danish and Chinese Adult Twins

Li, S., Kyvik, K. O., Pang, Z., Zhang, D., Duan, H., Tan, Q., Hjelmborg, J., Kruse, T. & Dalgård, C., feb. 2016, I : P L o S One. 11, 2, s. 1-14 e0148396.

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Environmental regulations
environmental law
Triglycerides
Blood pressure
phenotype
2017

Differences in genetic and environmental variation in adult BMI by sex, age, time period, and region: An individual-based pooled analysis of 40 twin cohorts

Silventoinen, K., Jelenkovic, A., Sund, R., Yokoyama, Y., Hur, Y. M., Cozen, W., Hwang, A. E., Mack, T. M., Honda, C., Inui, F., Iwatani, Y., Watanabe, M., Tomizawa, R., Pietilainen, K. H., Rissanen, A., Siribaddana, S. H., Hotopf, M., Sumathipala, A., Rijsdijk, F., Tan, Q. & 82 flere, Zhang, D., Pang, Z., Piirtola, M., Aaltonen, S., Oncel, S. Y., Aliev, F., Rebato, E., Hjelmborg, J. B., Christensen, K., Skytthe, A., Kyvik, K. O., Silberg, J. L., Eaves, L. J., Cutler, T. L., Ordonana, J. R., Sanchez-Romera, J. F., Colodro-Conde, L., Song, Y. M., Yang, S., Lee, K., Franz, C. E., Kremen, W. S., Lyons, M. J., Busjahn, A., Nelson, T. L., Whitfield, K. E., Kandler, C., Jang, K. L., Gatz, M., Butler, D. A., Stazi, M. A., Fagnani, C., D'Ippolito, C., Duncan, G. E., Buchwald, D., Martin, N. G., Medland, S. E., Montgomery, G. W., Jeong, H. U., Swan, G. E., Krasnow, R., Magnusson, P. K. E., Pedersen, N. L., Dahl Aslan, A. K., McAdams, T. A., Eley, T. C., Gregory, A. M., Tynelius, P., Baker, L. A., Tuvblad, C., Bayasgalan, G., Narandalai, D., Spector, T. D., Mangino, M., Lachance, G., Burt, S. A., Klump, K. L., Harris, J. R., Brandt, I., Nilsen, T. S., Krueger, R. F., McGue, M., Pahlen, S., Corley, R. P., Huibregtse, B. M., Bartels, M., Van Beijsterveldt, C. E. M., Willemsen, G., Goldberg, J. H., Rasmussen, F., Tarnoki, A. D., Tarnoki, D. L., Derom, C. A., Vlietinck, R. F., Loos, R. J. F., Hopper, J. L., Sung, J., Maes, H. H., Turkheimer, E., Boomsma, D. I., Sørensen, T. I. A. & Kaprio, J., 2017, I : American Journal of Clinical Nutrition. 106, 2, s. 457-466

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Far East
North America
Body Mass Index
Population
2018
69 Downloads (Pure)

DNA methylation age and perceived age in elderly Danish twins

Debrabant, B., Sørensen, M., Christiansen, L., Tan, Q., McGue, M., Christensen, K. & Hjelmborg, J. V. B., 1. jan. 2018, I : Mechanisms of Ageing and Development. 169, s. 40-44

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DNA Methylation
Epigenomics
2017
109 Downloads (Pure)

Identification, replication and characterization of epigenetic remodelling in the aging genome: a cross population analysis

Li, S., Christiansen, L., Christensen, K., Kruse, T. A., Redmond, P., Marioni, R. E., Deary, I. J. & Tan, Q., 2017, I : Scientific Reports. 7, 1, 8 s., 8183.

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Epigenomics
CpG Islands
Population
DNA Methylation
2015
105 Downloads (Pure)

Zygosity Differences in Height and Body Mass Index of Twins From Infancy to Old Age: A Study of the CODATwins Project

Jelenkovic, A., Yokoyama, Y., Sund, R., Honda, C., Bogl, L. H., Aaltonen, S., Ji, F., Ning, F., Pang, Z., Ordoñana, J. R., Sánchez-Romera, J. F., Colodro-Conde, L., Burt, S. A., Klump, K. L., Medland, S. E., Montgomery, G. W., Kandler, C., McAdams, T. A., Eley, T. C., Gregory, A. M. & 110 flere, Saudino, K. J., Dubois, L., Boivin, M., Tarnoki, A. D., Tarnoki, D. L., Haworth, C. M. A., Plomin, R., Öncel, S. Y., Aliev, F., Stazi, M. A., Fagnani, C., D'Ippolito, C., Craig, J. M., Saffery, R., Siribaddana, S. H., Hotopf, M., Sumathipala, A., Rijsdijk, F., Spector, T., Mangino, M., Lachance, G., Gatz, M., Butler, D. A., Bayasgalan, G., Narandalai, D., Freitas, D. L., Maia, J. A., Harden, K. P., Tucker-Drob, E. M., Kim, B., Chong, Y., Hong, C., Shin, H. J., Christensen, K., Skytthe, A., Kyvik, K. O., Derom, C. A., Vlietinck, R. F., Loos, R. J. F., Cozen, W., Hwang, A. E., Mack, T. M., He, M., Ding, X., Chang, B., Silberg, J. L., Eaves, L. J., Maes, H. H., Cutler, T. L., Hopper, J. L., Aujard, K., Magnusson, P. K. E., Pedersen, N. L., Aslan, A. K. D., Song, Y-M., Yang, S., Lee, K., Baker, L. A., Tuvblad, C., Bjerregaard-Andersen, M., Beck-Nielsen, H., Sodemann, M., Heikkilä, K., Tan, Q., Zhang, D., Swan, G. E., Krasnow, R., Jang, K. L., Knafo-Noam, A., Mankuta, D., Abramson, L., Lichtenstein, P., Krueger, R. F., McGue, M., Pahlen, S., Tynelius, P., Duncan, G. E., Buchwald, D., Corley, R. P., Huibregtse, B. M., Nelson, T. L., Whitfield, K. E., Franz, C. E., Kremen, W. S., Lyons, M. J., Ooki, S., Brandt, I., Nilsen, T. S., Inui, F., Watanabe, M., Bartels, M., van Beijsterveldt, T. C. E. M., Wardle, J., Llewellyn, C. H., Fisher, A., Rebato, E., Martin, N. G., Iwatani, Y., Hayakawa, K., Sung, J., Harris, J. R., Willemsen, G., Busjahn, A., Goldberg, J. H., Rasmussen, F., Hur, Y-M., Boomsma, D. I., Sørensen, T. I. A., Kaprio, J. & Silventoinen, K., okt. 2015, I : Twin Research and Human Genetics. 18, 5, s. 557-70

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Monozygotic Twins
Dizygotic Twins
Body Mass Index
Databases
2018

Weighted gene co-expression network analysis of microarray mRNA expression profiling in response to electroacupuncture

Mohammadnejad, A., Li, S., Duan, H., Lund, J., Li, W., Baumbach, J. & Tan, Q., dec. 2018, Proceedings of the 2018 IEEE International Conference on Bioinformatics and Biomedicine. Schmidt, H., Griol, D., Wang, H., Baumbach, J., Zheng, H., Callejas, Z., Hu, X., Dickerson, J. & Zhang, L. (red.). IEEE, s. 1876-1883 8621258

Publikation: Bidrag til bog/antologi/rapport/konference-proceedingKonferencebidrag i proceedingsForskningpeer review

Electroacupuncture
Messenger RNA
Periaqueductal Gray
Gene Ontology
2017

Gene by environment interaction in human longevity as observed in Danish birth cohorts from 1905 to 1915

Tan, Q., 2017. 1 s.

Publikation: Konferencebidrag uden forlag/tidsskriftPosterForskningpeer review

Gene-Environment Interaction
Alleles
Population Characteristics
Risk Reduction Behavior
Survival Analysis

Polygenic analysis of genome-wide SNP data identifies common variants on allergic rhinitis

Mohammadnejad, A., Brasch-Andersen, C., Haagerup, A., Vestbo, J., Baumbach, J. & Tan, Q., maj 2017. 1 s.

Publikation: Konferencebidrag uden forlag/tidsskriftPosterForskningpeer review

Single Nucleotide Polymorphism
Genome-Wide Association Study
Twin Studies
Human Genome
2018
52 Downloads (Pure)

A Case-only Genome-Wide Association Study on Gene-Sex Interaction in Allergic Rhinitis

Mohammadnejad, A., Brasch-Andersen, C., Li, W., Haagerup, A., Baumbach, J. & Tan, Q., sep. 2018, I : Annals of Allergy, Asthma, & Immunology. 121, 3, s. 366-367.e2

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2019
Monozygotic Twins
Immune System Diseases
Transcriptome
Individuality
Cognition
2018
Åben adgang
Twin Studies
MicroRNAs
Cognition
Neurobiology
Monozygotic Twins
2017
151 Downloads (Pure)

Weighted gene co-expression network analysis of expression data of monozygotic twins identifies specific modules and hub genes related to BMI.

Wang, W., Jiang, W., Hou, L., Duan, H., Wu, Y., Xu, C., Tan, Q., Li, S. & Zhang, D., 2017, I : BMC Genomics. 18, 17 s., 872.

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Monozygotic Twins
Databases
Transcriptome
Chylomicron Remnants
Chylomicrons
2016
130 Downloads (Pure)

Robust de novo pathway enrichment with KeyPathwayMiner 5

Alcaraz, N., List, M., Dissing-Hansen, M., Rehmsmeier, M., Tan, Q., Mollenhauer, J., Ditzel, H. & Baumbach, J., 2016, I : F1000Research. 2016, 5, 10 s., 1531.

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Perturbation techniques
Systems Biology
Computational Biology
Gold
Genes

Blood DNA methylation age is not associated with cognitive functioning in middle-aged monozygotic twins

Starnawska, A., Tan, Q., Lenart, A., McGue, M., Mors, O., Børglum, A. D., Christensen, K., Nyegaard, M. & Christiansen, L., 2016, I : Neurobiology of Aging. 50, s. 60-63

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Monozygotic Twins
DNA Methylation
Twin Studies
Epigenomics
Cognition

DNA methylation profiles of polycystic ovarian syndrome in Chinese women: A case-control study

Li, S., Duan, H., Zhu, D., Ren, A., Glintborg, D., Andersen, M., Skov, V., Thomassen, M., Kruse, T. A. & Tan, Q., 2016.

Publikation: Konferencebidrag uden forlag/tidsskriftPosterForskningpeer review

Polycystic Ovary Syndrome
DNA Methylation
Case-Control Studies
Epigenomics
Prolactin