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Forfatter

  • Moustapha Kassem
2019

Strontium functionalized scaffold for bone tissue engineering

Prabha, R. D., Nair, B. P., Ditzel, N., Kjems, J., Nair, P. D. & Kassem, M., 1. jan. 2019, I : Materials Science and Engineering C: Biomimetic Materials, Sensors and Systems. 94, s. 509-515

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

2011

PDX1- and NGN3-mediated in vitro reprogramming of human bone marrow-derived mesenchymal stromal cells into pancreatic endocrine lineages

Limbert, C., Päth, G., Ebert, R., Rothhammer, V., Kassem, M., Jakob, F. & Seufert, J., 2011, I : Cytotherapy. 13, 7, s. 802-13 12 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

DLK1 is a novel regulator of bone mass that mediates estrogen deficiency-induced bone loss in mice

Abdallah, B. M., Ditzel, N., Mahmood, A., Isa, A., Traustadottir, G. A., Schilling, A. F., Ruiz-Hidalgo, M-J., Laborda, J., Amling, M. & Kassem, M., 2011, I : Journal of Bone and Mineral Research. 26, 7, s. 1457-71 15 s.

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2019

Hedgehog Signaling Inhibition by Smoothened Antagonist BMS-833923 Reduces Osteoblast Differentiation and Ectopic Bone Formation of Human Skeletal (Mesenchymal) Stem Cells

Almuraikhi, N., Almasoud, N., Binhamdan, S., Younis, G., Ali, D., Manikandan, M., Vishnubalaji, R., Atteya, M., Siyal, A., Alfayez, M., Aldahmash, A., Kassem, M. & Alajez, N. M., 21. nov. 2019, I : Stem Cells International. 2019, 12 s., 3435901.

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2018

Romidepsin Promotes Osteogenic and Adipocytic Differentiation of Human Mesenchymal Stem Cells through Inhibition of Histondeacetylase Activity

Ali, D., Chalisserry, E. P., Manikandan, M., Hamam, R., Alfayez, M., Kassem, M., Aldahmash, A. & Alajez, N. M., 2018, I : Stem Cells International. 2018, 12 s., 2379546.

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2016

Transgelin is a TGFβ-inducible gene that regulates osteoblastic and adipogenic differentiation of human skeletal stem cells through actin cytoskeleston organization

Elsafadi, E., Manikandan, M., Dawud, R. A., Alajez, N. M., Hamam, R., Alfayez, M., Kassem, M., Aldahmash, A. & Mahmood, A., 2016, I : Cell Death & Disease. 7, s. e2321 14 s.

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181 Downloads (Pure)
2014

miR-141-3p inhibits human stromal (mesenchymal) stem cell proliferation and differentiation

Qiu, W. & Kassem, M., sep. 2014, I : BBA General Subjects. 1843, 9, s. 2114–2121

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2016

Bone morphogenetic protein 2 (BMP2) induces growth suppression and enhances chemosensitivity of human colon cancer cells

Vishnubalaji, R., Yue, S., Alfayez, M., Kassem, M., Liu, FF., Aldahmash, A. & Alajez, N. M., 29. sep. 2016, I : Cancer Cell International. 16, 12 s., 77.

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338 Downloads (Pure)
2013

Separate Developmental Programs for HLA-A and -B Cell Surface Expression during Differentiation from Embryonic Stem Cells to Lymphocytes, Adipocytes and Osteoblasts

Sabir, H. J., Nehlin, J. O., Qanie, D., Harkness, L., Prokhorova, T. A., Blagoev, B., Kassem, M., Isa, A. & Barington, T., 2013, I : P L o S One. 8, 1, s. e54366

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2014

MicroRNA-34a inhibits osteoblast differentiation and in vivo bone formation of human stromal stem cells

Chen, L., Holmstrøm, K., Qiu, W., Ditzel, N., Shi, K., Hokland, L. & Kassem, M., 2014, I : Stem Cells. 32, 4, s. 902-912 11 s., 24307639.

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2020

Identification of osteoclast-osteoblast coupling factors in humans reveals links between bone and energy metabolism

Weivoda, M. M., Chew, C. K., Monroe, D. G., Farr, J. N., Atkinson, E. J., Geske, J. R., Eckhardt, B., Thicke, B., Ruan, M., Tweed, A. J., McCready, L. K., Rizza, R. A., Matveyenko, A., Kassem, M., Andersen, T. L., Vella, A., Drake, M. T., Clarke, B. L., Oursler, M. J. & Khosla, S., 7. jan. 2020, I : Nature Communications. 11, 13 s., 87.

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2018

Molecular profiling of ALDH1+ colorectal cancer stem cells reveals preferential activation of MAPK, FAK, and oxidative stress prosurvival signalling pathways

Vishnubalaji, R., Manikandan, M., Fahad, M., Hamam, R., Alfayez, M., Kassem, M., Aldahmash, A. & Alajez, N. M., 2. mar. 2018, I : OncoTarget. 9, 17, s. 13551-13564

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2017

Legumain Regulates Differentiation Fate of Human Bone Marrow Stromal Cells and Is Altered in Postmenopausal Osteoporosis

Jafari, A., Qanie, D., Levin Andersen, T., Zhang, Y., Chen, L., Postert, B., Parsons, S., Ditzel, N., Khosla, S., Johansen, H. T., Kjærsgaard-Andersen, P., Delaisse, J. M., Abdallah, B. M., Hesselson, D., Solberg, R. & Kassem, M., 2017, I : Stem Cell Reports. 8, 2, s. 373-386

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2013

Telomere dysfunction leads to changes in microglial numbers and morphology in a mouse model of premature aging. Glia, Volume 61, Issue Suppl 1, S157.

Khan, A. M., Babcock, A., Kassem, M. & Finsen, B., 2013.

Publikation: Konferencebidrag uden forlag/tidsskriftKonferenceabstrakt til konferenceForskningpeer review

2014

Adult Stromal (Skeletal, Mesenchymal) Stem Cells: Advances Towards Clinical Applications.

Jafari, A., Harkness, L., Zaher, W. & Kassem, M., maj 2014, Adult Stem Cells, Stem Cell Biology and Regenerative Medicine. Turksen, K. (red.). Springer Science+Business Media, s. 359-373 15 s.

Publikation: Bidrag til bog/antologi/rapport/konference-proceedingBidrag til bog/antologiForskningpeer review

2011

Delta-like 1/fetal antigen-1 (Dlk1/FA1) is a novel regulator of chondrogenic cell differentiation via inhibition of the Akt kinase-dependent pathway

Chen, L., Qanie, D., Jafari, A., Taipaleenmaki, H., Jensen, C. H., Säämänen, A-M., Sanz, M. L. N., Laborda, J., Abdallah, B. M. & Kassem, M., 2011, I : Journal of Biological Chemistry. 286, 37, s. 32140-9 10 s.

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Flow perfusion culture of human mesenchymal stem cells on coralline hydroxyapatite scaffolds with various pore sizes

Bjerre, L., Bünger, C., Baatrup, A., Kassem, M. & Mygind, T., 2011, I : Journal of Biomedical Materials Research. Part A. 97A, 3, s. 251-63 13 s.

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Bone regeneration and stem cells

Arvidson, K., Abdallah, B. M., Applegate, L. A., Baldini, N., Cenni, E., Gomez-Barrena, E., Granchi, D., Kassem, M., Konttinen, Y. T., Mustafa, K. A., Pioletti, D. P., Sillat, T. & Finne-Wistrand, A., 2011, I : Journal of Cellular and Molecular Medicine. 15, 4, s. 718-746

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2019

ESTABLISHMENT OF A KNOCKDOWN MODEL FOR UNRAVELLING THE PATHOGENESIS OF MANTLE CELL LYMPHOMA

Valentin Hansen, S., Cédile, O., Hansen, M. C., Christensen, J. H., Chen, L., Kassem, M., Abildgaard, N. & Nyvold, C. G., jun. 2019.

Publikation: Konferencebidrag uden forlag/tidsskriftKonferenceabstrakt til konferenceForskningpeer review

2018

International Harmonization and Standardization between Denmark and Germany: The German-Danish Interreg project BONEBANK

Maushagen, R., Gemoll, T., Oberlaender, M., Faccinetti, G., Figge, L., Kock-Schoppenhauer, A-K., Duhm-Harbeck, P., Niessen, L., Unger, A., Wendlandt, R., Kowal, J. M., Haakonsson, A. K., Bober, C., Diercks, K., Nassutt, R., Buescher, R., Reimers, N., Schmal, H., Frahm, T., Eckers, A. & 5 flere, Brilling, J., Barington, T., Kassem, M., Schulz, A-P. & Habermann, J. K., 31. jul. 2018.

Publikation: Konferencebidrag uden forlag/tidsskriftPosterForskningpeer review

2011

Development of novel monoclonal antibodies that define differentiation stages of human stromal (mesenchymal) stem cells

Andersen, D. C., Kortesidis, A., Zannettino, A. C. W., Kratchmarova, I., Chen, L., Jensen, O. N., Teisner, B., Gronthos, S., Jensen, C. H. & Kassem, M., 2011, I : Molecules and Cells. 32, 2, s. 133-142 10 s.

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2020

Identification of osteolineage cell-derived extracellular vesicle cargo implicated in hematopoietic support

Morhayim, J., Ghebes, C. A., Erkeland, S. J., ter Borg, M. N. D., Hoogenboezem, R. M., Bindels, E. M. J., van Alphen, F. P. J., Kassem, M., van Wijnen, A. J., Cornelissen, J. J., van Leeuwen, J. P., van der Eerden, B. C. J., Voermans, C., van de Peppel, J. & Braakman, E., 1. apr. 2020, I : FASEB Journal. 34, 4, s. 5435-5452

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2017

The performance of a new generation of 3D printed and drug and stem cell loaded implants in vitro and in vivo

Bonde Jensen, M., Slots, C., Ditzel, N., Hedegaard, M. A. B., Andersen, T. E., Thygesen, T., Kassem, M. & Andersen, M. Ø., 2. nov. 2017. 1 s.

Publikation: Konferencebidrag uden forlag/tidsskriftKonferenceabstrakt til konferenceForskningpeer review

2011

Circulating osteogenic cells: implications for injury, repair, and regeneration

Pignolo, R. J. & Kassem, M., 2011, I : Journal of Bone and Mineral Research. 26, 8, s. 1685-93 9 s.

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2018

Establishing lobular-like and interlobular-like fibroblast cell lines from human breast reduction mammoplasties

Morsing, M., Jafari, A., Kassem, M., Petersen, O. W. & Ronnov-Jessen, L., jul. 2018, I : Cancer research. 78, Suppl. 13, 1010.

Publikation: Bidrag til tidsskriftKonferenceabstrakt i tidsskriftForskning

2011

Telomerase-Deficient Mice Exhibit Bone Loss Owing to Defects in Osteoblasts and Increased Osteoclastogenesis by Inflammatory Microenvironment

Saeed, H., Abdallah, B. M., Ditzel, N., Catala-Lehnen, P., Qiu, W. M., Amling, M. & Kassem, M., 2011, I : Journal of Bone and Mineral Research. 26, 7, s. 1494-1505 12 s.

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2020

Transgelin is a poor prognostic factor associated with advanced colorectal cancer (CRC) stage promoting tumor growth and migration in a TGFβ-dependent manner

Elsafadi, M., Manikandan, M., Almalki, S., Mahmood, A., Shinwari, T., Vishnubalaji, R., Mobarak, M., Alfayez, M., Aldahmash, A., Kassem, M. & Alajez, N. M., 1. maj 2020, I : Cell Death and Disease. 11, 5, 13 s., 341.

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2011

CXCR4 expression in human mesenchymal stem cells enhances in vitro migration

Andersen, R. K., Clausen, C., Jørgensen, F., Holst, B., Zaher, W. & Kassem, M., 2011.

Publikation: Konferencebidrag uden forlag/tidsskriftPosterForskning

2019

Identification of novel factors involved in the coupling of bone resorption and bone formation in humans reveals RANKL/DPP4 as a new link between bone remodeling and energy metabolism

Weivoda, M., Chew, C. K., Monroe, D., Atkinson, E., Farr, J., Thicke, B., Ruan, M., Tweed, A., Eckhardt, B., McCready, L., Geske, J., Rizza, R., Vella, A., Matveyenko, A., Drake, M., Clarke, B., Oursler, M. J., Khosla, S., Kassem, M. & Andersen, T., dec. 2019, I : Journal of Bone and Mineral Research. 34, Suppl. 1, s. 18 1 s., 1051.

Publikation: Bidrag til tidsskriftKonferenceabstrakt i tidsskriftForskningpeer review

2018

Induction of quiescence (G0) in bone marrow stromal stem cells enhances their stem cell characteristics

Rumman, M., Majumder, A., Harkness, L., Venugopal, B., Vinay, M. B., Pillai, M. S., Kassem, M. & Dhawan, J., jul. 2018, I : Stem Cell Research. 30, s. 69-80

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2011

Snorc is a novel cartilage specific small membrane proteoglycan expressed in differentiating and articular chondrocytes

Heinonen, J., Taipaleenmäki, H., Roering, P., Takatalo, M., Harkness, L., Sandholm, J., Uusitalo-Järvinen, H., Kassem, M., Kiviranta, I., Laitala-Leinonen, T. & Säämänen, A-M., 2011, I : Osteoarthritis and Cartilage. 19, 8, s. 1026-35 10 s.

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2016

Aging and bone

Gimble, J. M., Floyd, Z. E., Kassem, M. & Nuttall, M. E., 2016, Osteoporosis in Older Persons: Advances in Pathophysiology and Therapeutic Approaches. Duque, G. & Kiel, D. P. (red.). 2. udg. Springer, s. 23-42

Publikation: Bidrag til bog/antologi/rapport/konference-proceedingBidrag til bog/antologiForskningpeer review

Effect of vitamin D replacement on indexes of insulin resistance in overweight elderly individuals: a randomized controlled trial

Fuleihan G, EI-H., Baddoura, R., Habib, R. H., Halaby, G., Arabi, A., Rahme, M., Singh, R. J., Kassem, M., Mahfoud, Z., Hoteit, M., Daher, R. T. & Kassir, M-F., aug. 2016, I : The American Journal of Clinical Nutrition. 104, 2, s. 315-323

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2014

Surface-modified functionalized polycaprolactone scaffolds for bone repair: In vitro and in vivo experiments

Jensen, J., Rolfing, J. H. D., Svend Le, D. Q., Kristiansen, A. A., Nygaard, J. V., Bjerre Hokland, L., Bendtsen, M., Kassem, M., Lysdahl, H. & Bunger, C. E., sep. 2014, I : Journal of Biomedical Materials Research. Part A. 102, 9, s. 2993-3003 11 s., 24123983.

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Establishing quiescence in human bone marrow stromal stem cells leads to enhanced osteoblast marker expression

Harkness, L., Rumman, M., Kassem, M. & Dhawan, J., 18. jun. 2014. 1 s.

Publikation: Konferencebidrag uden forlag/tidsskriftPosterForskningpeer review

2013

Sphingosine 1 Phosphate (S1P) Receptors 1 and 2 Coordinately Induce Osteoblast Migration Through S1P Activation of Complementary Kinase Pathways

Quint, P., Ruan, M., Pederson, L., Kassem, M., Westendorf, J. J., Khosla, S. & Oursler, M. J., 2013, I : Journal of Biological Chemistry. 288, s. 5398-5406

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2019

Osteogenesis depends on commissioning of a network of stem cell transcription factors that act as repressors of adipogenesis

Rauch, A., Haakonsson, A. K., Madsen, J. G. S., Larsen, M., Forss, I., Madsen, M. R., Van Hauwaert, E. L., Wiwie, C., Jespersen, N. Z., Tencerova, M., Nielsen, R., Larsen, B. D., Röttger, R., Baumbach, J., Scheele, C., Kassem, M. & Mandrup, S., apr. 2019, I : Nature Genetics. 51, 4, s. 716-727

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2016

Characterization of Cellular and Molecular Heterogeneity of Bone Marrow Stromal Cells

Elsafadi, M., Manikandan, M., Atteya, M., Hashmi, J. A., Iqbal, Z., Aldahmash, A., Alfayez, M., Kassem, M. & Mahmood, A., 2016, I : Stem Cells International. 2016, 18 s., 9378081.

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2018

NR2F1 mediated down-regulation of osteoblast differentiation was rescued by bone morphogenetic protein-2 (BMP-2) in human MSC

Manikandan, M., Abuelreich, S., Elsafadi, M., Alsalman, H., Almalak, H., Siyal, A., Hashmi, J. A., Aldahmash, A., Kassem, M., Alfayez, M. & Mahmood, A., 1. nov. 2018, I : Differentiation. 104, s. 36-41

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2016

Evidence of two distinct functionally specialized fibroblast lineages in breast stroma

Morsing, M., Klitgaard, M. C., Jafari, A., Villadsen, R., Kassem, M., Petersen, O. W. & Rønnov-Jessen, L., 3. nov. 2016, I : Breast Cancer Research (Online). 18, 108.

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2019

Metabolic programming determines the lineage-differentiation fate of murine bone marrow stromal progenitor cells

Tencerova, M., Rendina-Ruedy, E., Neess, D., Færgeman, N., Figeac, F., Ali, D., Danielsen, M., Haakonsson, A., Rosen, C. J. & Kassem, M., 1. dec. 2019, I : Bone Research. 7, 14 s., 35.

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2017

CHD1 regulates cell fate determination by activation of differentiation-induced genes

Baumgart, S. J., Najafova, Z., Hossan, T., Xie, W., Nagarajan, S., Kari, V., Ditzel, N., Kassem, M. & Johnsen, S. A., 2017, I : Nucleic Acids Research. 45, 13, s. 7722-7735

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2013

Pleiotropic effects of cancer cells' secreted factors on human stromal (mesenchymal) stem cells

Al-toub, M., Almusa, A., Almajed, M., Al-Nbaheen, M., Kassem, M., Aldahmash, A. & Alajez, N., 2013, I : Stem Cell Research & Therapy. 4, 114, 19 s., 24405819.

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2016

microRNA expression profiling on individual breast cancer patients identifies novel panel of circulating microRNA for early detection

Hamam, R., Ali, A. M., Alsaleh, K. A., Kassem, M., Alfayez, M., Aldahmash, A. & Alajez, N. M., 2016, I : Scientific Reports. 2016, 8 s., 25997.

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Transcription factor ZNF25 is associated with osteoblast differentiation of human skeletal stem cells

Twine, N. A., Harkness, L., Kassem, M. & Wilkins, M. R., 2016, I : BMC Genomics. 17, 15 s., 872.

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Normal hematopoiesis and lack of β-catenin activation in osteoblasts of patients and mice harboring Lrp5 gain of function mutations

Galan-Diez, M., Isa, A., Ponzetti, M., Nielsen, M. F. M., Kassem, M. & Kousteni, S., 2016, I : BBA General Subjects. 1863, 3, s. 490-8

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2017

Bone morphology in IKBKG (NEMO) mutation positive women: A case-control study

Frost, M., Tencerova, M., Ejersted, C. A., Svaneby, D., Levin Andersen, T., Kassem, M., McAlister, W. H., Novack, D., Whyte, M. P. & Frederiksen, A. L., 2017.

Publikation: Konferencebidrag uden forlag/tidsskriftPosterForskningpeer review

2011

Levels of serotonin, sclerostin, bone turnover markers as well as bone density and microarchitecture in patients with high bone mass phenotype due to a mutation in Lrp5

Nielsen, M. F., Andersen, T. E., Gossiel, F., Hansen, S., Bollerslev, J., Van Hul, W., Eastell, R., Kassem, M. & Brixen, K., 2011, I : Journal of Bone and Mineral Research. 26, 8, s. 1721-1728 8 s.

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2016

CD146/MCAM defines functionality of human bone marrow stromal stem cell populations

Harkness, L., Zaher, W., Ditzel, N., Isa, A. & Kassem, M., 2016, I : Stem Cell Research & Therapy. 7, 1, s. 4-16 13 s.

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2017

MicroRNA-4739 regulates osteogenic and adipocytic differentiation of immortalized human bone marrow stromal cells via targeting LRP3

Elsafadi, M., Manikandan, M., Alajez, N. M., Hamam, R., Dawud, R. A., Aldahmash, A., Iqbal, Z., Alfayez, M., Kassem, M. & Mahmood, A., 2017, I : Stem Cell Research. 20, s. 94-104

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