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  • Moustapha Kassem
2015

CD34 defines an osteoprogenitor cell population in mouse bone marrow stromal cells

Abdallah, B. M., Al-Shammary, A., Skagen, P., Abu Dawud, R., Adjaye, J., Aldahmash, A. & Kassem, M., 21. sep. 2015, I : Stem Cell Research. 15, 3, s. 449-458 10 s.

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219 Downloads (Pure)
2019

Strontium functionalized scaffold for bone tissue engineering

Prabha, R. D., Nair, B. P., Ditzel, N., Kjems, J., Nair, P. D. & Kassem, M., 1. jan. 2019, I : Materials Science and Engineering C: Biomimetic Materials, Sensors and Systems. 94, s. 509-515

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2011

PDX1- and NGN3-mediated in vitro reprogramming of human bone marrow-derived mesenchymal stromal cells into pancreatic endocrine lineages

Limbert, C., Päth, G., Ebert, R., Rothhammer, V., Kassem, M., Jakob, F. & Seufert, J., 2011, I : Cytotherapy. 13, 7, s. 802-13 12 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

DLK1 is a novel regulator of bone mass that mediates estrogen deficiency-induced bone loss in mice

Abdallah, B. M., Ditzel, N., Mahmood, A., Isa, A., Traustadottir, G. A., Schilling, A. F., Ruiz-Hidalgo, M-J., Laborda, J., Amling, M. & Kassem, M., 2011, I : Journal of Bone and Mineral Research. 26, 7, s. 1457-71 15 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

2019

Hedgehog Signaling Inhibition by Smoothened Antagonist BMS-833923 Reduces Osteoblast Differentiation and Ectopic Bone Formation of Human Skeletal (Mesenchymal) Stem Cells

Almuraikhi, N., Almasoud, N., Binhamdan, S., Younis, G., Ali, D., Manikandan, M., Vishnubalaji, R., Atteya, M., Siyal, A., Alfayez, M., Aldahmash, A., Kassem, M. & Alajez, N. M., 21. nov. 2019, I : Stem Cells International. 2019, 12 s., 3435901.

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2015

Pharmacological Inhibition of Protein Kinase G1 Enhances Bone Formation by Human Skeletal Stem Cells Through Activation of RhoA-Akt Signaling.

Jafari, A., Siersbæk, M., Chen, L., Qanie, D. W. M., Zaher, W., Abdallah, B. & Kassem, M., 2015, I : Stem Cells. 33, 7, s. 2219–2231

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2016

Transgelin is a TGFβ-inducible gene that regulates osteoblastic and adipogenic differentiation of human skeletal stem cells through actin cytoskeleston organization

Elsafadi, E., Manikandan, M., Dawud, R. A., Alajez, N. M., Hamam, R., Alfayez, M., Kassem, M., Aldahmash, A. & Mahmood, A., 2016, I : Cell Death & Disease. 7, s. e2321 14 s.

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181 Downloads (Pure)
2014

miR-141-3p inhibits human stromal (mesenchymal) stem cell proliferation and differentiation

Qiu, W. & Kassem, M., sep. 2014, I : BBA General Subjects. 1843, 9, s. 2114–2121

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2016

Bone morphogenetic protein 2 (BMP2) induces growth suppression and enhances chemosensitivity of human colon cancer cells

Vishnubalaji, R., Yue, S., Alfayez, M., Kassem, M., Liu, FF., Aldahmash, A. & Alajez, N. M., 29. sep. 2016, I : Cancer Cell International. 16, 12 s., 77.

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338 Downloads (Pure)
2013

Separate Developmental Programs for HLA-A and -B Cell Surface Expression during Differentiation from Embryonic Stem Cells to Lymphocytes, Adipocytes and Osteoblasts

Sabir, H. J., Nehlin, J. O., Qanie, D., Harkness, L., Prokhorova, T. A., Blagoev, B., Kassem, M., Isa, A. & Barington, T., 2013, I : P L o S One. 8, 1, s. e54366

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2016

microRNA expression profiling on individual breast cancer patients identifies novel panel of circulating microRNA for early detection

Hamam, R., Ali, A. M., Alsaleh, K. A., Kassem, M., Alfayez, M., Aldahmash, A. & Alajez, N. M., 2016, I : Scientific Reports. 2016, 8 s., 25997.

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209 Downloads (Pure)
2014

MicroRNA-34a inhibits osteoblast differentiation and in vivo bone formation of human stromal stem cells

Chen, L., Holmstrøm, K., Qiu, W., Ditzel, N., Shi, K., Hokland, L. & Kassem, M., 2014, I : Stem Cells. 32, 4, s. 902-912 11 s., 24307639.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

2020

Identification of osteoclast-osteoblast coupling factors in humans reveals links between bone and energy metabolism

Weivoda, M. M., Chew, C. K., Monroe, D. G., Farr, J. N., Atkinson, E. J., Geske, J. R., Eckhardt, B., Thicke, B., Ruan, M., Tweed, A. J., McCready, L. K., Rizza, R. A., Matveyenko, A., Kassem, M., Andersen, T. L., Vella, A., Drake, M. T., Clarke, B. L., Oursler, M. J. & Khosla, S., 7. jan. 2020, I : Nature Communications. 11, 13 s., 87.

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41 Downloads (Pure)
2017

Legumain Regulates Differentiation Fate of Human Bone Marrow Stromal Cells and Is Altered in Postmenopausal Osteoporosis

Jafari, A., Qanie, D., Levin Andersen, T., Zhang, Y., Chen, L., Postert, B., Parsons, S., Ditzel, N., Khosla, S., Johansen, H. T., Kjærsgaard-Andersen, P., Delaisse, J. M., Abdallah, B. M., Hesselson, D., Solberg, R. & Kassem, M., 2017, I : Stem Cell Reports. 8, 2, s. 373-386

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2013

Telomere dysfunction leads to changes in microglial numbers and morphology in a mouse model of premature aging. Glia, Volume 61, Issue Suppl 1, S157.

Khan, A. M., Babcock, A., Kassem, M. & Finsen, B., 2013.

Publikation: Konferencebidrag uden forlag/tidsskriftKonferenceabstrakt til konferenceForskningpeer review

2014

Adult Stromal (Skeletal, Mesenchymal) Stem Cells: Advances Towards Clinical Applications.

Jafari, A., Harkness, L., Zaher, W. & Kassem, M., maj 2014, Adult Stem Cells, Stem Cell Biology and Regenerative Medicine. Turksen, K. (red.). Springer Science+Business Media, s. 359-373 15 s.

Publikation: Bidrag til bog/antologi/rapport/konference-proceedingBidrag til bog/antologiForskningpeer review

2017

Bone morphology in IKBKG (NEMO) mutation positive women: A case-control study

Frost, M., Tencerova, M., Ejersted, C. A., Svaneby, D., Levin Andersen, T., Kassem, M., McAlister, W. H., Novack, D., Whyte, M. P. & Frederiksen, A. L., 2017.

Publikation: Konferencebidrag uden forlag/tidsskriftPosterForskningpeer review

2011

Delta-like 1/fetal antigen-1 (Dlk1/FA1) is a novel regulator of chondrogenic cell differentiation via inhibition of the Akt kinase-dependent pathway

Chen, L., Qanie, D., Jafari, A., Taipaleenmaki, H., Jensen, C. H., Säämänen, A-M., Sanz, M. L. N., Laborda, J., Abdallah, B. M. & Kassem, M., 2011, I : Journal of Biological Chemistry. 286, 37, s. 32140-9 10 s.

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Flow perfusion culture of human mesenchymal stem cells on coralline hydroxyapatite scaffolds with various pore sizes

Bjerre, L., Bünger, C., Baatrup, A., Kassem, M. & Mygind, T., 2011, I : Journal of Biomedical Materials Research. Part A. 97A, 3, s. 251-63 13 s.

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2017

Circulating microRNAs in breast cancer: novel diagnostic and prognostic biomarkers

Hamam, R., Hamam, D., Alsaleh, K. A., Kassem, M., Zaher, W., Alfayez, M., Aldahmash, A. & Alajez, N. M., 7. sep. 2017, I : Cell Death & Disease. 8, 9, 12 s., e3045.

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2011

Bone regeneration and stem cells

Arvidson, K., Abdallah, B. M., Applegate, L. A., Baldini, N., Cenni, E., Gomez-Barrena, E., Granchi, D., Kassem, M., Konttinen, Y. T., Mustafa, K. A., Pioletti, D. P., Sillat, T. & Finne-Wistrand, A., 2011, I : Journal of Cellular and Molecular Medicine. 15, 4, s. 718-746

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2015

Inhibiting actin depolymerization enhances osteoblast differentiation and bone formation in human stromal stem cells

Chen, L., Shi, K., Frary, C., Ditzel, N., Hu, H., Qiu, W. & Kassem, M., 2015, I : Stem Cell Research. 15, 2, s. 281-289

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2019

ESTABLISHMENT OF A KNOCKDOWN MODEL FOR UNRAVELLING THE PATHOGENESIS OF MANTLE CELL LYMPHOMA

Valentin Hansen, S., Cédile, O., Hansen, M. C., Christensen, J. H., Chen, L., Kassem, M., Abildgaard, N. & Nyvold, C. G., jun. 2019.

Publikation: Konferencebidrag uden forlag/tidsskriftKonferenceabstrakt til konferenceForskningpeer review

2011

Development of novel monoclonal antibodies that define differentiation stages of human stromal (mesenchymal) stem cells

Andersen, D. C., Kortesidis, A., Zannettino, A. C. W., Kratchmarova, I., Chen, L., Jensen, O. N., Teisner, B., Gronthos, S., Jensen, C. H. & Kassem, M., 2011, I : Molecules and Cells. 32, 2, s. 133-142 10 s.

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2020

Identification of osteolineage cell-derived extracellular vesicle cargo implicated in hematopoietic support

Morhayim, J., Ghebes, C. A., Erkeland, S. J., ter Borg, M. N. D., Hoogenboezem, R. M., Bindels, E. M. J., van Alphen, F. P. J., Kassem, M., van Wijnen, A. J., Cornelissen, J. J., van Leeuwen, J. P., van der Eerden, B. C. J., Voermans, C., van de Peppel, J. & Braakman, E., 1. apr. 2020, I : FASEB Journal. 34, 4, s. 5435-5452

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2017

The performance of a new generation of 3D printed and drug and stem cell loaded implants in vitro and in vivo

Bonde Jensen, M., Slots, C., Ditzel, N., Hedegaard, M. A. B., Andersen, T. E., Thygesen, T., Kassem, M. & Andersen, M. Ø., 2. nov. 2017. 1 s.

Publikation: Konferencebidrag uden forlag/tidsskriftKonferenceabstrakt til konferenceForskningpeer review

2011

Circulating osteogenic cells: implications for injury, repair, and regeneration

Pignolo, R. J. & Kassem, M., 2011, I : Journal of Bone and Mineral Research. 26, 8, s. 1685-93 9 s.

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Cancer stem cell overexpression of nicotinamide N-methyltransferase enhances cellular radiation resistance

D'Andrea, F. P., Safwat, A., Kassem, M., Gautier, L., Overgaard, J. & Horsman, M. R., 1. jun. 2011, I : Radiotherapy & Oncology. 99, 3, s. 373-8 6 s.

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Telomerase-Deficient Mice Exhibit Bone Loss Owing to Defects in Osteoblasts and Increased Osteoclastogenesis by Inflammatory Microenvironment

Saeed, H., Abdallah, B. M., Ditzel, N., Catala-Lehnen, P., Qiu, W. M., Amling, M. & Kassem, M., 2011, I : Journal of Bone and Mineral Research. 26, 7, s. 1494-1505 12 s.

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2020

Transgelin is a poor prognostic factor associated with advanced colorectal cancer (CRC) stage promoting tumor growth and migration in a TGFβ-dependent manner

Elsafadi, M., Manikandan, M., Almalki, S., Mahmood, A., Shinwari, T., Vishnubalaji, R., Mobarak, M., Alfayez, M., Aldahmash, A., Kassem, M. & Alajez, N. M., 1. maj 2020, I : Cell Death and Disease. 11, 5, 13 s., 341.

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2015

Proteomic Validation of Transcript Isoforms, Including Those Assembled from RNA-Seq Data

Tay, A. P., Pang, C. N. I., Twine, N. A., Hart-Smith, G., Harkness, L., Kassem, M. & Wilkins, M. R., 2015, I : Journal of Proteome Research. 14, 9, s. 3541-3554

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2016

MicroRNA-320 suppresses colorectal cancer by targeting SOX4, FOXM1, and FOXQ1

Vishnubalaji, R., Hamam, R., Shijun, Y., AI-Obeed, O., Kassem, M., Liu, F-F., Aldahmash, A. & Alajez, N. M., 2016, I : Oncotarget. 7, 24, s. 35789–35802

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2011

CXCR4 expression in human mesenchymal stem cells enhances in vitro migration

Andersen, R. K., Clausen, C., Jørgensen, F., Holst, B., Zaher, W. & Kassem, M., 2011.

Publikation: Konferencebidrag uden forlag/tidsskriftPosterForskning

2015

Anabolic compounds for treating and preventing bone loss diseases

Jafari, A., Chen, L., Kassem, M. & Abdallah, B., 7. maj 2015, Patentnr. WO2013167475 (A1), 7. maj 2015, Prioritetsdato 3. maj 2013, Prioritetsnr. US201314399726

Publikation: Patent

2019

Identification of novel factors involved in the coupling of bone resorption and bone formation in humans reveals RANKL/DPP4 as a new link between bone remodeling and energy metabolism

Weivoda, M., Chew, C. K., Monroe, D., Atkinson, E., Farr, J., Thicke, B., Ruan, M., Tweed, A., Eckhardt, B., McCready, L., Geske, J., Rizza, R., Vella, A., Matveyenko, A., Drake, M., Clarke, B., Oursler, M. J., Khosla, S., Kassem, M. & Andersen, T., dec. 2019, I : Journal of Bone and Mineral Research. 34, Suppl. 1, s. 18 1 s., 1051.

Publikation: Bidrag til tidsskriftKonferenceabstrakt i tidsskriftForskningpeer review

2011

Snorc is a novel cartilage specific small membrane proteoglycan expressed in differentiating and articular chondrocytes

Heinonen, J., Taipaleenmäki, H., Roering, P., Takatalo, M., Harkness, L., Sandholm, J., Uusitalo-Järvinen, H., Kassem, M., Kiviranta, I., Laitala-Leinonen, T. & Säämänen, A-M., 2011, I : Osteoarthritis and Cartilage. 19, 8, s. 1026-35 10 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

2016

Aging and bone

Gimble, J. M., Floyd, Z. E., Kassem, M. & Nuttall, M. E., 2016, Osteoporosis in Older Persons: Advances in Pathophysiology and Therapeutic Approaches. Duque, G. & Kiel, D. P. (red.). 2. udg. Springer, s. 23-42

Publikation: Bidrag til bog/antologi/rapport/konference-proceedingBidrag til bog/antologiForskningpeer review

Effect of vitamin D replacement on indexes of insulin resistance in overweight elderly individuals: a randomized controlled trial

Fuleihan G, EI-H., Baddoura, R., Habib, R. H., Halaby, G., Arabi, A., Rahme, M., Singh, R. J., Kassem, M., Mahfoud, Z., Hoteit, M., Daher, R. T. & Kassir, M-F., aug. 2016, I : The American Journal of Clinical Nutrition. 104, 2, s. 315-323

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2017

SERPINB2 is a novel TGFβ-responsive lineage fate determinant of human bone marrow stromal cells

Elsafadi, M., Manikandan, M., Atteya, M., Abu Dawud, R., Almalki, S., Ali Kaimkhani, Z., Aldahmash, A., Alajez, N. M., Alfayez, M., Kassem, M. & Mahmood, A., 1. dec. 2017, I : Scientific Reports. 7, 15 s., 10797.

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2014

Surface-modified functionalized polycaprolactone scaffolds for bone repair: In vitro and in vivo experiments

Jensen, J., Rolfing, J. H. D., Svend Le, D. Q., Kristiansen, A. A., Nygaard, J. V., Bjerre Hokland, L., Bendtsen, M., Kassem, M., Lysdahl, H. & Bunger, C. E., sep. 2014, I : Journal of Biomedical Materials Research. Part A. 102, 9, s. 2993-3003 11 s., 24123983.

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Establishing quiescence in human bone marrow stromal stem cells leads to enhanced osteoblast marker expression

Harkness, L., Rumman, M., Kassem, M. & Dhawan, J., 18. jun. 2014. 1 s.

Publikation: Konferencebidrag uden forlag/tidsskriftPosterForskningpeer review

2013

Sphingosine 1 Phosphate (S1P) Receptors 1 and 2 Coordinately Induce Osteoblast Migration Through S1P Activation of Complementary Kinase Pathways

Quint, P., Ruan, M., Pederson, L., Kassem, M., Westendorf, J. J., Khosla, S. & Oursler, M. J., 2013, I : Journal of Biological Chemistry. 288, s. 5398-5406

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2019

Metabolic programming determines the lineage-differentiation fate of murine bone marrow stromal progenitor cells

Tencerova, M., Rendina-Ruedy, E., Neess, D., Færgeman, N., Figeac, F., Ali, D., Danielsen, M., Haakonsson, A., Rosen, C. J. & Kassem, M., 1. dec. 2019, I : Bone Research. 7, 14 s., 35.

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2015

Association between in vivo bone formation and ex vivo migratory capacity of human bone marrow stromal cells

Andersen, R. K., Zaher, W., Larsen, K. H., Ditzel, N., Drews, K., wruck, W., Adjaye, J., Abdallah, B. & Kassem, M., 8. okt. 2015, I : Stem Cell Research & Therapy. 6, s. 196

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2017

Simple additive manufacturing of an osteoconductive ceramic using suspension melt extrusion

Slots, C., Bonde Jensen, M., Ditzel, N., Hedegaard, M. A. B., Borg, S. W., Albrektsen, O., Thygesen, T., Kassem, M. & Andersen, M. Ø., 2017, I : Dental Materials. 33, 2, s. 198–208

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314 Downloads (Pure)
2014

Primary mesenchymal stem cells in human transplanted lungs are CD90/CD105 perivascularly located tissue-resident cells

Rolandsson, S., Andersson Sjöland, A., Brune, J. C., Li, H., Kassem, M., Mertens, F., Westergren, A., Eriksson, L., Hansson, L., Skog, I., Bjermer, L., Scheding, S. & Westergren-Thorsson, G., 2014, I : B M J Open Respiratory Research. 1, 1, s. e000027

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Low/Negative Expression of PDGFR-α Identifies the Candidate Primary Mesenchymal Stromal Cells in Adult Human Bone Marrow

Li, H., Ghazanfari, R., Zacharaki, D., Ditzel, N., Isern, J., Ekblom, M., Méndez-Ferrer, S., Kassem, M. & Scheding, S., 9. dec. 2014, I : Stem Cell Reports. 3, 6, s. 965-974

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2011

TGFb signalling inhibits DLK1 expression during chondrogenesis in vitro

Harkness, L., Taipaleenmaki, H., Saamanen, A-M., Kassem, M. & Abdallah, B., 15. jun. 2011.

Publikation: Konferencebidrag uden forlag/tidsskriftPosterForskning

2019
2015

Molecular characterisation of stromal populations derived from human embryonic stem cells: Similarities to immortalised bone marrow derived stromal stem cells

Harkness, L., Twine, N. A., Abu Dawud, R., Jafari, A., Aldahmash, A., Wilkins, M. R., Adjaye, J. & Kassem, M., 2015, I : Bone Reports. 3, s. 32-39

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