Find publikationer

Søg emneordskoncepter
Valgte filtre
2012

Pathway analysis of variation in DNA repair genes indicates involvement of repair of oxidative DNA lesions in human longevity

Sørensen, M., Debrabant, B., Mengel-From, J., Stevnsner, T. V., Bohr, V., Tan, Q. & Christiansen, L., nov. 2012.

Publikation: Konferencebidrag uden forlag/tidsskriftPosterForskning

Twin-based DNA methylation analysis takes the center stage of studies of human complex diseases

Zhang, D., Li, S., Tan, Q. & Pang, Z., 2012, I : Journal of Genetics and Genomics. 39, 11, s. 581-6 6 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

DNA Methylation
Epigenomics
Twin Studies
Environmental Exposure

Heritability and whole genome linkage of pulse pressure in Chinese twin pairs

Jiang, W., Zhang, D., Pang, Z., Li, S., Duan, H., Wang, S. & Tan, Q., 2012, I : Twin Research and Human Genetics. 15, 6, s. 759-766

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Lod Score
Population
Chromosomes, Human, Pair 18
Dizygotic Twins
Chromosomes, Human, Pair 12
2017

Enriched power of case-only design in detecting gene-gene interaction using disease concordant twins

Li, W., Vandin, F., Baumbach, J. & Tan, Q., 22. jun. 2017.

Publikation: Konferencebidrag uden forlag/tidsskriftPosterForskningpeer review

Genes
Computer simulation

Gene by environment interaction in human longevity as observed in Danish birth cohorts from 1905 to 1915

Tan, Q., 2017. 1 s.

Publikation: Konferencebidrag uden forlag/tidsskriftPosterForskningpeer review

Gene-Environment Interaction
Alleles
Population Characteristics
Risk Reduction Behavior
Survival Analysis
2016

DiMmeR: Discovery of Multiple Differentially Methylated Regions

Almeida, D. M., Skov, I., Silva, A., Vandin, F., Tan, Q., Röttger, R. & Baumbach, J., 2016.

Publikation: Konferencebidrag uden forlag/tidsskriftPosterForskning

The epigenomics of polycystic ovarian syndrome: from pathogenesis to clinical manifestations

Li, S., Zhu, D., Duan, H. & Tan, Q., dec. 2016, I : Gynecological Endocrinology. 32, 12, s. 942-946

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Polycystic Ovary Syndrome
Epigenomics
Comorbidity
Ovarian Diseases
Reproductive Health
2017

A simulation study on power of epigenome-wide association analysis using disease-discordant twin design

Li, W., Baumbach, J., Christiansen, L. & Tan, Q., 28. maj 2017.

Publikation: Konferencebidrag uden forlag/tidsskriftPosterForskningpeer review

Association reactions
Methylation
Microarrays
Computer simulation
Costs
2018
Åben adgang
Twin Studies
MicroRNAs
Cognition
Neurobiology
Monozygotic Twins
2012

High-Resolution Genome-Wide Linkage Mapping Identifies Susceptibility Loci for BMI in the Chinese Population

Zhang, D. F., Pang, Z., Li, S., Thomassen, M., Wang, S., Jiang, W., Hjelmborg, J. V. B., Kruse, T. A., Kyvik, K. O., Christensen, K. & Tan, Q., apr. 2012, I : Obesity. 20, 4, s. 830-3 4 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Chromosome Mapping
Lod Score
Population
Single Nucleotide Polymorphism
Chromosomes, Human, Pair 14
2017

Handling blood cell composition in epigenetic studies on ageing

Tan, Q., Heijmans, B. T., Hjelmborg, J. V. B., Thinggaard, M. S., Christensen, K. & Christiansen, L., 2017, I : International Journal of Epidemiology. 46, 5, s. 1717–1718

Publikation: Bidrag til tidsskriftKommentar/debatForskningpeer review

2012

A cross-sectional analysis of age and sex patterns in grip strength, tooth loss, near vision and hearing levels in Chinese aged 50-74 years

Wu, Y., Pang, Z., Zhang, D., Jiang, W., Wang, S., Li, S., Kruse, T. A., Christensen, K. & Tan, Q., 3. sep. 2012, I : Archives of Gerontology and Geriatrics. 54, 2, s. e213-e220

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Tooth Loss
Hearing
Cross-Sectional Studies
Sex Characteristics
Visual Acuity

Epigenetic Epidemiology of Complex Diseases Using Twins

Tan, Q., jan. 2013, I : Medical Epigenetics. 1, s. 46-51

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

2019

Network based analysis of microarray gene expression profiles in response to electroacupuncture

Mohammadnejad, A., Li, S., Duan, H. & Tan, Q., 4. sep. 2019, I : Journal of Traditional and Complementary Medicine. 7 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Åben adgang
Electroacupuncture
Transcriptome
Periaqueductal Gray
Gene Ontology
2012

Genetic variation in TERT and TERC and human leukocyte telomere length and longevity: a cross-sectional and longitudinal analysis

Soerensen, M., Thinggaard, M., Nygaard, M., Dato, S., Tan, Q., Hjelmborg, J., Andersen-Ranberg, K., Stevnsner, T. V., Bohr, V., Kimura, M., Aviv, A., Christensen, K. & Christiansen, L., apr. 2012, I : Aging Cell. 11, 2, s. 223-7 5 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Telomerase
Telomere
Cross-Sectional Studies
Single Nucleotide Polymorphism
Haplotypes
2013

Twins for epigenetic studies of human aging and development

Tan, Q., Christiansen, L., Thomassen, M., Kruse, T. A. & Christensen, K., 2013, I : Ageing Research Reviews. 12, 1, s. 182-187

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Twin Studies
Epigenomics
Genes
Aging of materials
DNA sequences
2019
Monozygotic Twins
Immune System Diseases
Transcriptome
Individuality
Cognition
2012

Prediction of breast cancer metastasis by gene expression profiles: A comparison of metagenes and single genes

Burton, M., Thomassen, M., Tan, Q. & Kruse, T. A., 2012, I : Cancer Informatics. 11, s. 193-217 25 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

2017
123 Downloads (Pure)

Disease-Concordant Twins Empower Genetic Association Studies

Tan, Q., Li, W. & Vandin, F., jan. 2017, I : Annals of Human Genetics. 81, 1, s. 20-26

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Åben adgang
Fil
Genetic Association Studies
Dizygotic Twins
Sample Size
Monozygotic Twins
Diseases in Twins
2018

Weighted gene co-expression network analysis of microarray mRNA expression profiling in response to electroacupuncture

Mohammadnejad, A., Li, S., Duan, H., Lund, J., Li, W., Baumbach, J. & Tan, Q., dec. 2018, Proceedings of the 2018 IEEE International Conference on Bioinformatics and Biomedicine. Schmidt, H., Griol, D., Wang, H., Baumbach, J., Zheng, H., Callejas, Z., Hu, X., Dickerson, J. & Zhang, L. (red.). IEEE, s. 1876-1883 8621258

Publikation: Bidrag til bog/antologi/rapport/konference-proceedingKonferencebidrag i proceedingsForskningpeer review

Electroacupuncture
Messenger RNA
Periaqueductal Gray
Gene Ontology

Circulating, Cell-Free Micro-RNA Profiles Reflect Discordant Development of Dementia in Monozygotic Twins

Mengel-From, J., Rønne, M. E., Carlsen, A. L., Skogstrand, K., Larsen, L. A., Tan, Q., Christiansen, L., Christensen, K. & Heegaard, N. H. H., 1. jan. 2018, I : Journal of Alzheimer's disease : JAD. 63, 2, s. 591-601

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Åben adgang
Monozygotic Twins
MicroRNAs
Immunoassay
Lipoproteins
Longitudinal Studies
2017

The gene expression and immunohistochemical time-course of diphenylcyclopropenone induced contact allergy in healthy humans following repeated epicutaneous challenges

Mose, K. F., Burton, M., Thomassen, M., Andersen, F., Kruse, T. A., Tan, Q., Skov, L., Almose Røpke, M., Litman, T., Clemmensen, O., Kristensen, B. W., S. Friedmann, P. & Andersen, K. E., 2017, I : Experimental Dermatology. 26, 10, s. 926–933

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Hypersensitivity
diphenylcyclopropenone
Polymerase Chain Reaction
Interleukin-17
Gene Expression Profiling
2016

Epigenetic drift in the aging genome: a ten-year follow-up in an elderly twin cohort

Tan, Q., Heijmans, B. T., Hjelmborg, J. V. B., Sørensen, M., Christensen, K. & Christiansen, L., 2016, I : International Journal of Epidemiology. 45, 4, s. 1146-1158

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Cytosine
Guanine
Epigenomics
DNA Methylation
Survival Analysis
2018

Network analysis of DNA methylation of visceral adipose tissue comparing obese individuals with and without type 2 diabetes

Mohammadnejad, A., Li, W., Lund, J., Baumbach, J. & Tan, Q., 25. sep. 2018.

Publikation: Konferencebidrag uden forlag/tidsskriftPosterForskningpeer review

DNA methylation linked to all-cause mortality in older people: An epigenome-wide association study.

Lund, J., Baumbach, J. & Tan, Q., mar. 2018.

Publikation: Konferencebidrag uden forlag/tidsskriftPosterForskningpeer review

DNA Methylation
G-Protein-Coupled Receptors
Proportional Hazards Models
Epigenomics
Skeleton
2013

Genome-wide linkage analysis for human longevity: Genetics of Healthy Aging Study

Beekman, M., Blanché, H., Perola, M., Hervonen, A., Bezrukov, V., Sikora, E., Flachsbart, F., Christiansen, L., De Craen, A. J. M., Kirkwood, T. B. L., Rea, I. M., Poulain, M., Robine, J-M., Valensin, S., Stazi, M. A., Passarino, G., Deiana, L., Gonos, E. S., Paternoster, L., Sørensen, T. & 21 flere, Tan, Q., Helmer, Q., van den Akker, E. B., Deelen, J., Martella, F., Cordell, H. J., Ayers, K. L., Vaupel, J. W., Törnwall, O., Johnson, T. E., Schreiber, S., Lathrop, M., Skytthe, A., Westendorp, R. G. J., Christensen, K., Gampe, J., Nebel, A., Houwing-Duistermaat, J. J., Slagboom, P. E., Franceschi, C. & GEHA consortium, 2013, I : Aging Cell. 12, 2, s. 184-93

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Medical Genetics
Alleles
Genome-Wide Association Study
Meta-Analysis
Siblings
2014

RNA profiling reveals familial aggregation of molecular subtypes in non-BRCA1/2 breast cancer families

Larsen, M. J., Thomassen, M., Tan, Q., Lænkholm, A. V., Bak, M., Sørensen, K. P., Andersen, M. K., Kruse, T. A. & Gerdes, A-M., 2014, I : B M C Medical Genomics. 7, s. 9 9.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Åben adgang
RNA
Neoplasms
Mutation
Penetrance
Germ-Line Mutation
2017

A case-only genome-wide association study for assessing gene-sex interaction in Allergic rhinitis

Mohammadnejad, A., Brasch-Andersen, C., Haagerup, A., Vestbo, J., Baumbach, J. & Tan, Q., aug. 2017.

Publikation: Konferencebidrag uden forlag/tidsskriftPosterForskningpeer review

Genome-Wide Association Study
Single Nucleotide Polymorphism
Chromosomes, Human, Pair 12
Posters
Chromosomes, Human, Pair 5
2014

Long non-coding RNA expression profiles in hereditary haemorrhagic telangiectasia

Tørring, P. M., Larsen, M. J., Kjeldsen, A. D., Ousager, L. B., Tan, Q. & Brusgaard, K., 2014, I : PLOS ONE. 9, 3, e90272.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Long Noncoding RNA
transcriptome
probes (equipment)
Tissue
Microarrays
2013

Genetic Alterations within the DENND1A Gene in Patients with Polycystic Ovary Syndrome (PCOS)

Eriksen, M. B., Nielsen, M. F. B., Brusgaard, K., Tan, Q., Andersen, M. S., Glintborg, D. & Gaster, M., 27. sep. 2013, I : PLOS ONE. 8, 9, s. e77186

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

polycystic ovary syndrome
Polycystic Ovary Syndrome
Polymorphism
Nucleotides
Genes

Circulating surfactant protein D is associated to mortality in elderly women: A twin study

Johansson, H. W., Thinggaard, M., Tan, Q., Johansson, S. L., Schlosser, A., Christensen, K., Holmskov, U. & Sorensen, G. L., 2013, I : Immunobiology. 218, 5, s. 712-717

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Pulmonary Surfactant-Associated Protein D
Twin Studies
Confidence Intervals
Lung
Survival Analysis
2013

Interactions between Social/ behavioral factors and ADRB2 genotypes may be associated with health at advanced ages in China

Zeng, Y., Cheng, L. G., Zhao, L., Tan, Q. H., Feng, Q. S., Chen, H. S., Shen, K., Li, J. X., Zhang, F. Y., Cao, H. Q., Gregory, S. G., Yang, Z., Gu, J., Tao, W., Tian, X. L. & Hauser, E. R., 2013, I : B M C Geriatrics. 13, 13 s., 91.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

China
Alleles
Cognition
Health
Leisure Activities
2018
116 Downloads (Pure)

Genetics of Obesity Traits: A Bivariate Genome-Wide Association Analysis

Wu, Y., Duan, H., Tian, X., Xu, C., Wang, W., Jiang, W., Pang, Z., Zhang, D. & Tan, Q., 16. maj 2018, I : Frontiers in Genetics. 9, MAY, 9 s., 179.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Åben adgang
Fil
Genome-Wide Association Study
Dizygotic Twins
Body Mass Index
Twin Studies
Quantitative Trait Loci
2013

Genetic investigation into ethnic disparity in polycystic ovarian syndrome

Li, S., Zhu, D., Duan, H. & Tan, Q., 2013, I : Gynecological Endocrinology. 29, 10, s. 878-882

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Polycystic Ovary Syndrome
Population
Genetic Association Studies
DNA Sequence Analysis
Epigenomics

Two-level mixed modeling of longitudinal pedigree data for genetic association analysis: 5th International Conference on Bioinformatics and Computational Biology 2013, BICoB 2013

Tan, Q., 2013, 5th International Conference on Bioinformatics and Computational Biology 2013. s. 193-197 5 s.

Publikation: Bidrag til bog/antologi/rapport/konference-proceedingKonferencebidrag i proceedingsForskningpeer review

2019

Global microRNA profiling of metastatic conjunctival melanoma

Mikkelsen, L. H., Andersen, M., Andreasen, S., Larsen, A-C., Tan, Q., Toft, P. B., Wadt, K. & Heegaard, S., okt. 2019, I : Melanoma Research. 29, 5, s. 465-473

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

MicroRNAs
Melanoma
Down-Regulation
Neoplasms
Referral and Consultation
2017
164 Downloads (Pure)

Epigenome-wide association study of cognitive functioning in middle-aged monozygotic twins

Starnawska, A., Tan, Q., McGue, M., Mors, O., Børglum, A. D., Christensen, K., Nyegaard, M. & Christiansen, L., 2017, I : Frontiers in Aging Neuroscience. 9, DEC, 10 s., 413.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Åben adgang
Fil
Monozygotic Twins
DNA Methylation
Epigenomics
Population
Alzheimer Disease
2015
97 Downloads (Pure)

The genetic basis for cognitive ability, memory, and depression symptomatology in middle-aged and elderly chinese twins

Xu, C., Sun, J., Ji, F., Tian, X., Duan, H., Zhai, Y., Wang, S., Pang, Z., Zhang, D., Zhao, Z., Li, S., Hjelmborg, J. V. B., Christensen, K. & Tan, Q., feb. 2015, I : Twin Research and Human Genetics. 18, 1, s. 79-85

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Åben adgang
Fil
Depression
Cognition
Geriatrics
Population
Multivariate Analysis
2013

Epigenome-wide association study on identical twins discordant for birth weight

Tan, Q., Nielsen, M. F. M. & Christiansen, L., okt. 2013.

Publikation: Konferencebidrag uden forlag/tidsskriftPosterForskningpeer review

Monozygotic Twins
DNA Methylation
Epigenomics
Prenatal Nutritional Physiological Phenomena
Low Birth Weight Infant
2017
128 Downloads (Pure)

Identification, replication and characterization of epigenetic remodelling in the aging genome: a cross population analysis

Li, S., Christiansen, L., Christensen, K., Kruse, T. A., Redmond, P., Marioni, R. E., Deary, I. J. & Tan, Q., 15. aug. 2017, I : Scientific Reports. 7, 1, 8 s., 8183.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Åben adgang
Fil
Epigenomics
CpG Islands
Population
DNA Methylation
2018
155 Downloads (Pure)

Association of miR-548c-5p, miR-7-5p, miR-210-3p, miR-128-3p with recurrence in systemically untreated breast cancer

Block, I., Burton, M., Sørensen, K. P., Andersen, L., Larsen, M. J., Bak, M., Cold, S., Thomassen, M., Tan, Q. & Kruse, T. A., 6. feb. 2018, I : OncoTarget. 9, 10, s. 9030-9042

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Åben adgang
Fil
2014

Epigenetic signature of birth weight discordance in adult twins

Tan, Q., Nielsen, M. F. M., Heijmans, B. T., von Bornemann Hjelmborg, J., Tobi, E. W., Christensen, K. & Christiansen, L., dec. 2014, I : B M C Genomics. 15, 1062.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Epigenomics
Monozygotic Twins
Health
Low Birth Weight Infant
Proxy
2019
150 Downloads (Pure)

Epigenome-wide association study of depression symptomatology in elderly monozygotic twins

Starnawska, A., Tan, Q., Sørensen, M., McGue, M., Mors, O., Børglum, A. D., Christensen, K., Nyegaard, M. & Christiansen, L., 2. sep. 2019, I : Translational Psychiatry. 9, 1, 14 s., 214.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Åben adgang
Fil
Monozygotic Twins
Depression
DNA Methylation
Epigenomics
Flow Cytometry
2014
Genes
Alleles
Genetic Heterogeneity
Medical Genetics
Population
2015
104 Downloads (Pure)

OpenLabNotes: An Electronic Laboratory Notebook Extension for OpenLabFramework

List, M., Franz, M., Tan, Q., Mollenhauer, J. & Baumbach, J., 2015, I : Journal of Integrative Bioinformatics. 12, 3, 10 s., 274.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Åben adgang
Fil
2019
111 Downloads (Pure)

DNA methylome profiling of all-cause mortality in comparison with age-associated methylation patterns

Lund, J., Li, S., Baumbach, J., Svane, A. M., Hjelmborg, J. V. B., Christiansen, L., Christensen, K., Redmond, P., Marioni, R. E., Deary, I. J. & Tan, Q., 8. feb. 2019, I : Clinical Epigenetics. 11, 8 s., 23.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Åben adgang
Fil
DNA Methylation
Genome-Wide Association Study
Survival Analysis
Proportional Hazards Models
Epigenomics
2016

Differentially Methylated Genomic Regions in Birth-Weight Discordant Twin Pairs

Chen, M., Baumbach, J., Vandin, F., Röttger, R., Vieira Barbosa, E. G., Dong, M., Nielsen, M. F. M., Christiansen, L. & Tan, Q., 2016, I : Annals of Human Genetics. 80, 2, s. 81-87

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

DNA Methylation
Epigenomics
Monozygotic Twins
Chromosomes, Human, Pair 1
Health