Fuhrmann Fonden - Investigation of the PPARG2 enhancer network in mesenchymal stem cell differentiation by pairwise enhancer deletion

Projekter: ProjektPrivate fonde



The aim of this project is to determine the role of specific regulatory regions in the PPARG locus in maintenance of 3D gene regulatory networks. This will be investigated by deleting selected regions (so-called enhancers) alone or in combination, followed by evaluation of transcription, chromatin topology and the activity of other enhancers in the locus.
Effektiv start/slut dato01/11/201931/12/2021