Intet foto af Signe Bek Sørensen

Signe Bek Sørensen

20112019
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Publikationer 2011 2019

2019

Identification of disease-associated traits and clonotypes in the T-cell receptor repertoire of monozygotic twins affected by inflammatory bowel diseases

Rosati, E., Pogorelyy, M. V., Dowds, C. M., Moller, F. T., Sorensen, S. B., Lebedev, Y. B., Frey, N., Schreiber, S., Spehlmann, M. E., Andersen, V., Mamedov, I. Z. & Franke, A., 11. nov. 2019, I : Journal of Crohn's and Colitis.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Monozygotic Twins
T-Cell Antigen Receptor
Inflammatory Bowel Diseases
Denmark
Artifacts

Polymorphisms at phase I-metabolizing enzyme and hormone receptor loci influence the response to anti-TNF therapy in rheumatoid arthritis patients

Canet, L. M., Sánchez-Maldonado, J. M., Cáliz, R., Ramos, A. R., Lupiañez, C. B., Canhão, H., Martínez-Bueno, M., Escudero, A., Segura-Catena, J., Sorensen, S. B., Hetland, M. L., Soto-Pino, M. J., Ferrer, M. A., García, A., Glintborg, B., Filipescu, I., Pérez-Pampin, E., González-Utrilla, A., Nevot, M. Á. L., Conesa-Zamora, P. & 10 flere, Broeder, A. D., De Vita, S., Jacobsen, S. E. H., Collantes-Estevez, E., Quartuccio, L., Canzian, F., Fonseca, J. E., Coenen, M. J. H., Andersen, V. & Sainz, J., feb. 2019, I : The Pharmacogenomics Journal. 19, s. 83-96

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Hormones
Enzymes
Pharmaceutical Preparations
Single Nucleotide Polymorphism
Haplotypes

Polymorphisms in the NFkB, TNF-alpha, IL-1beta, and IL-18 pathways are associated with response to anti-TNF therapy in Danish patients with inflammatory bowel disease

The Danish IBD Genetics Working Group, apr. 2019, I : Alimentary Pharmacology and Therapeutics. 49, 7, s. 890-903

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Interleukin-18
Inflammatory Bowel Diseases
Ulcerative Colitis
Tumor Necrosis Factor-alpha
Crohn Disease
2018
82 Downloads (Pure)

Genetically determined high activities of the TNF-alpha, IL23/IL17, and NFkB pathways were associated with increased risk of ankylosing spondylitis

Sode, J., Bank, S., Vogel, U., Andersen, P. S., Sørensen, S. B., Bojesen, A. B., Andersen, M. R., Brandslund, I., Dessau, R. B., Hoffmann, H. J., Glintborg, B., Hetland, M. L., Locht, H., Heegaard, N. H. & Andersen, V., 12. sep. 2018, I : BMC Medical Genetics. 19, 16 s., 165.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Åben adgang
Fil
Tumor Necrosis Factor-alpha
Interleukin-18
Odds Ratio
Confidence Intervals
Antirheumatic Agents

Hvem har gavn af medicinsk behandling med præparater rettet mod TNF-α

Jawhara, M. & Sørensen, S. B., 2018, I : BestPractice Reumatologi. 2018, feb.

Publikation: Bidrag til tidsskriftTidsskriftartikelFormidling

115 Downloads (Pure)

Impact of red and processed meat and fibre intake on treatment outcomes among patients with chronic inflammatory diseases: protocol for a prospective cohort study of prognostic factors and personalised medicine

Christensen, R., Heitmann, B. L., Andersen, K. W., Nielsen, O. H., Sørensen, S. B., Jawhara, M., Bygum, A., Hvid, L., Grauslund, J., Wied, J., Glerup, H., Fredberg, U., Villadsen, J. A., Kjær, S. G., Fallingborg, J., Moghadd, S. A. G. R., Knudsen, T., Brodersen, J., Frøjk, J., Dahlerup, J. F. & 21 flere, Bojesen, A. B., Sorensen, G. L., Thiel, S., Færgeman, N. J., Brandslund, I., Bennike, T. B., Stensballe, A., Schmidt, E. B., Franke, A., Ellinghaus, D., Rosenstiel, P., Raes, J., Boye, M., Werner, L., Nielsen, C. L., Munk, H. L., Nexøe, A. B., Ellingsen, T., Holmskov, U., Kjeldsen, J. & Andersen, V., feb. 2018, I : B M J Open. 8, 2, 17 s., e018166.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Åben adgang
Fil
Precision Medicine
Cohort Studies
Prospective Studies
Tumor Necrosis Factor-alpha
Hidradenitis Suppurativa
2017
213 Downloads (Pure)

A Proposal for a Study on Treatment Selection and Lifestyle Recommendations in Chronic Inflammatory Diseases: A Danish Multidisciplinary Collaboration on Prognostic Factors and Personalised Medicine

Andersen, V., Holmskov, U., Sørensen, S. B., Jawhara, M., Andersen, K. W., Bygum, A., Sylvester Hvid, L., Grauslund, J., Wied, J., Glerup, H., Fredberg, U., Villadsen, J. A., Kjær, S. G., Fallingborg, J., Moghadd, S. A. G. R., Knudsen, T., Brodersen, J., Frøjk, J., Dahlerup, J. F., Nielsen, O. H. & 18 flere, Christensen, R., Bojesen, A. B., Sorensen, G. L., Thiel, S., Færgeman, N. J., Brandslund, I., Stensballe, A., Schmidt, E. B., Franke, A., Ellinghaus, D., Rosenstiel, P., Raes, J., Heitmann, B., Boye, M., Lindgaard Nielsen, C., Werner, L., Kjeldsen, J. & Ellingsen, T., 2017, I : Nutrients. 9, 5, 16 s., 499.

Publikation: Bidrag til tidsskriftLetterForskningpeer review

Åben adgang
Fil
Precision Medicine
tumor necrosis factors
lifestyle
medicine
inflammatory bowel disease
106 Downloads (Pure)

Systematic review and meta-analysis: pharmacogenetics of anti-TNF treatment response in rheumatoid arthritis

Bek, S., Bojesen, A. B., Nielsen, J. V., Sode, J., Bank, S., Vogel, U. & Andersen, V., 2017, I : Pharmacogenomics Journal. 17, s. 403–411

Publikation: Bidrag til tidsskriftReviewForskningpeer review

Åben adgang
Fil
Pharmacogenetics
Meta-Analysis
Genome-Wide Association Study
PubMed
Single Nucleotide Polymorphism
2016
112 Downloads (Pure)

Systematic review genetic biomarkers associated with anti-TNF treatment response in inflammatory bowel diseases

Sørensen, S. B., Nielsen, J. V., Bo Bojesen, A., Franke, A., Bank, S., Vogel, U. & Andersen, V., 15. jul. 2016, I : Alimentary Pharmacology and Therapeutics. 44, 6, s. 554-567

Publikation: Bidrag til tidsskriftReviewForskningpeer review

Åben adgang
Fil
Inflammatory Bowel Diseases
Tumor Necrosis Factor-alpha
Genetic Markers
Crohn Disease
Meta-Analysis
2015
105 Downloads (Pure)

Compromised epidermal barrier stimulates Harderian gland activity and hypertrophy in ACBP-/- mice

Sørensen, S. B., Neess, D., Dixen, K., Bloksgaard, M., Marcher, A-B., Chemnitz, J., Færgeman, N. J. & Mandrup, S., sep. 2015, I : Journal of Lipid Research. 56, 9, s. 1738-46 9 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Åben adgang
Fil
Diazepam Binding Inhibitor
Harderian Gland
Genes
Lipids
Lubrication

Fysiologiske effekter af deletion af Acbp genet i huden

Sørensen, S. B., 2015, Odense: Syddansk Universitet. Det Naturvidenskabelige Fakultet.

Publikation: Bog/antologi/afhandling/rapportPh.d.-afhandlingForskning

Long-chain acyl-CoA esters in metabolism and signaling: Role of acyl-CoA binding proteins

Neess, D., Sørensen, S. B., Engelsby, H., Gallego, S. F. & Færgeman, N. J., 18. apr. 2015, I : Progress in Lipid Research. 59, s. 1-25

Publikation: Bidrag til tidsskriftReviewForskningpeer review

Diazepam Binding Inhibitor
Acyl Coenzyme A
Metabolism
Cell signaling
Esters
2013

Acute cold response of brown adipose tissue analyzed by mass spectrometry-based lipidomics and RNA-seq

Marcher, A-B., Madsen, J. G. S., Nielsen, R., Bek, S., Vihervaara, T., Xuan Ta, H., Sylvänne, T. & Mandrup, S., 13. aug. 2013.

Publikation: Konferencebidrag uden forlag/tidsskriftPosterForskning

Delayed Hepatic Adaptation to Weaning in ACBP(-/-) Mice Is Caused by Disruption of the Epidermal Barrier

Neess, D., Bek, S., Bloksgaard, M., Marcher, A-B., Færgeman, N. J. & Mandrup, S., 2013, I : Cell Reports. 5, 5, s. 1403–1412

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Diazepam Binding Inhibitor
Weaning
Liver
Genes
Lipids
2012
Kidney Concentrating Ability
Aquaporin 3
Diazepam Binding Inhibitor
Kidney
Water Deprivation

The acyl-CoA binding protein is required for normal epidermal barrier function in mice

Bloksgaard, M., Bek, S., Marcher, A-B., Neess, D., Brewer, J., Hannibal-Bach, H. K., Helledie, T., Fenger, C., Due, M., Berzina, Z., Neubert, R., Chemnitz, J., Finsen, B., Clemmensen, A., Wilbertz, J., Saxtorph, H., Knudsen, J., Bagatolli, L. & Mandrup, S., 2012, I : Journal of Lipid Research. 53, 10, s. 2162-74 13 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Diazepam Binding Inhibitor
Skin
Diglycerides
Nonesterified Fatty Acids
Sebum

The suppression of the lipogenic gene program in the brown adipose tissue at birth is disturbed in Acyl-CoA binding protein-deficient mice

Marcher, A-B., Mondini, E., Neess, D., Bek, S., Cinti, S. & Mandrup, S., 26. aug. 2012.

Publikation: Konferencebidrag uden forlag/tidsskriftPosterForskning

2011

Acyl-CoA binding protein is required for normal fatty acid chain elongation and lipid synthesis in Harderian gland in mice

Bidragets oversatte titel: Acyl-CoA bindende protein er nødvendig for normal fedt syre kædeforlængelse og lipid syntese i den Harderske kirtel i musBek, S., Dixen, K., Mølgaard, M. B., Ejsing, C. S., Neess, D., Marcher, A-B., Færgeman, N. J. & Mandrup, S., 8. sep. 2011.

Publikation: Konferencebidrag uden forlag/tidsskriftPosterFormidling

Disruption of the Acyl-CoA binding protein gene delays hepatic adaptation to metabolic changes at weaning

Neess, D., Marcher, A-B., Bloksgaard, M., Bek, S., Elle, I. C., Færgeman, N. J. & Mandrup, S., 12. jan. 2011. 1 s.

Publikation: Konferencebidrag uden forlag/tidsskriftPosterForskning

Disruption of the acyl-coa binding protein gene delays hepatic adaptation to metabolic changes at weaning

Neess, D., Bloksgaard, M., Sørensen, S. B., Marcher, A-B., Elle, I. C., Helledie, T., Due, M., Pagmantidis, V., Finsen, B., Wilbertz, J., Kruhoeffer, M., Faergeman, N. & Mandrup, S., 2011, I : Journal of Biological Chemistry. 286, s. 3460-3472

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Sterol Regulatory Element Binding Proteins
Weaning
Acyl Coenzyme A
Carrier Proteins
Diazepam Binding Inhibitor