Intet foto af Rasmus Siersbæk

Rasmus Siersbæk

20082021
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Publikationer 2008 2017

  • 12 Tidsskriftartikel
  • 8 Poster
  • 1 Ph.d.-afhandling
Filtrer
Tidsskriftartikel
2017

Dynamic Rewiring of Promoter-Anchored Chromatin Loops during Adipocyte Differentiation

Siersbæk, R., Madsen, J. G. S., Javierre, B. M., Nielsen, R., Bagge, E. K., Cairns, J., Wingett, S. W., Traynor, S., Spivakov, M., Fraser, P. & Mandrup, S., 2017, I : Molecular Cell. 66, 3, s. 420-435.e5

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Adipocytes
Histones
Lysine
Acetylation
Transcriptional Activation

Hierarchical role for transcription factors and chromatin structure in genome organization along adipogenesis

Sarusi Portuguez, A., Schwartz, M., Siersbaek, R., Nielsen, R., Sung, M-H., Mandrup, S., Kaplan, T. & Hakim, O., 2017, I : F E B S Journal. 284, 19, s. 3230-3244

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Adipogenesis
3T3-L1 Cells
Genome-Wide Association Study
Adipocytes
Cluster Analysis
2014

CD1d-mediated presentation of endogenous lipid antigens by adipocytes requires microsomal triglyceride transfer protein (MTP)

Rakhshandehroo, M., Gijzel, S. M. W., Siersbæk, R., Broekema, M. F., de Haar, C., Schipper, H. S., Boes, M., Mandrup, S. & Kalkhoven, E., 25. jun. 2014, I : Journal of Biological Chemistry. 289, s. 22128-22139

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Adipocytes
Lipids
Antigens
CCAAT-Enhancer-Binding Proteins
Adipose Tissue

Molecular architecture of transcription factor hotspots in early adipogenesis

Siersbæk, R., Baek, S., Rabiee, A., Nielsen, R., Traynor, S., Clark, N., Sandelin, A., Jensen, O. N., Sung, M-H., Hager, G. L. & Mandrup, S., 12. jun. 2014, I : Cell Reports. 7, 5, s. 1434-42 9 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Adipogenesis
Transcription Factors
Chromatin
Genes
Adipocytes
Adipocytes
RNA Sequence Analysis
Adipogenesis
Chromatin Assembly and Disassembly
Chromatin Immunoprecipitation

Transcription factor cooperativity in early adipogenic hotspots and super-enhancers

Siersbæk, R., Rabiee, A., Nielsen, R., Sidoli, S., Traynor, S., Loft, A., Poulsen, L. L. C., Rogowska-Wrzesinska, A., Jensen, O. N. & Mandrup, S., 12. jun. 2014, I : Cell Reports. 7, 5, s. 1443–1455 13 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Transcription Factors
Adipogenesis
Complex networks
Crosstalk
Gene expression
2012

Transcriptional networks and chromatin remodeling controlling adipogenesis

Siersbæk, R., Nielsen, R. & Mandrup, S., 2012, I : Trends in Endocrinology and Metabolism. 23, 2, s. 56-64 9 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Adipogenesis
Chromatin Assembly and Disassembly
Adipocytes
Epigenomics
Fibroblasts
2011

Extensive chromatin remodelling and establishment of transcription factor 'hotspots' during early adipogenesis

Siersbæk, R., Nielsen, R., John, S., Sung, M-H., Baek, S., Loft, A., Hager, G. L. & Mandrup, S., 20. apr. 2011, I : E M B O Journal. 30, 8, s. 1459-72 14 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

CCAAT-Enhancer-Binding Proteins
Adipogenesis
Chromatin Assembly and Disassembly
Peroxisome Proliferator-Activated Receptors
Chromatin

Transcriptional networks controlling adipocyte differentiation

Siersbæk, R. & Mandrup, S., 2011, I : Cold Spring Harbor Laboratory. Symposia on Quantitative Biology. 76, s. 247-55 9 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskning

Adipocytes
Transcription Factors
Chromatin
Adipogenesis
Chromatin Assembly and Disassembly
2010

Molecular basis for gene-specific transactivation by nuclear receptors

Jørgensen, M. A., Siersbæk, R. & Mandrup, S., 28. dec. 2010, I : BBA General Subjects. 1812, 8, s. 824-835

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Cytoplasmic and Nuclear Receptors
Transcriptional Activation
Protein Binding
DNA
Health

PPARgamma in adipocyte differentiation and metabolism: novel insights from genome-wide studies

Siersbaek, R., Nielsen, R. & Mandrup, S., 4. aug. 2010, I : FEBS letters. 584, 15, s. 3242-9 8 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

PPAR gamma
Adipocytes
Metabolism
CCAAT-Enhancer-Binding Protein-alpha
Genes
2008

Genome-wide profiling of PPARgamma:RXR and RNA polymerase II occupancy reveals temporal activation of distinct metabolic pathways and changes in RXR dimer composition during adipogenesis

Nielsen, R., Pedersen, T. A., Hagenbeek, D., Moulos, P., Siersbaek, R., Megens, E., Denissov, S., Børgesen, M., Francoijs, K-J., Mandrup, S. & Stunnenberg, H. G., 1. nov. 2008, I : Genes & Development. 22, 21, s. 2953-2967 14 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Adipogenesis
RNA Polymerase II
PPAR gamma
Metabolic Networks and Pathways
Adipocytes