Poul Nielsen

ph.d.

  • Campusvej 55

    5230 Odense M

    Danmark

1994 …2021
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Publikationer 1994 2019

  • 106 Tidsskriftartikel
  • 5 Konferenceabstrakt til konference
  • 1 Bidrag til bog/antologi
  • 1 Konferenceabstrakt i tidsskrift
1998

An Efficient Protocol for the Stereoselective Dihydroxylation of Ene-Ester Systems

Hermitage, S. A., Murphy, A., Nielsen, P. & Roberts, S. M., 1998, I : Tetrahedron. 54, s. 13185-13202

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

A Novel Class of Oligonucleotide Analogues Containing 2'-O,3'-C-Linked [3.2.0]Bicyclo-arabinonucleoside Monomers: Synthesis, Thermal Affinity Studies and Molecular Modelling

Christensen, N. K., Petersen, M., Nielsen, P., Jacobsen, J. P., Olsen, C. E. & Wengel, J., 1998, I : Journal of the American Chemical Society. 120, 22, s. 5458-5463

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

LNA (Locked Nucleic Acids): An RNA Mimic Forming Exceedingly Stable LNA:LNA Duplexes

Koshkin, A. A., Nielsen, P., Meldgaard, M., Rajwanshi, V. K., Singh, S. K. & Wengel, J., 1998, I : Journal of the American Chemical Society. 120, 50, s. 13252-13253

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

LNA (locked nucleic acids): synthesis and high-affinity nucleic acid recognition

Singh, S. K., Nielsen, P., Koshkin, A. A. & Wengel, J., 1998, I : Chemical Communications. 1998, 4, s. 455-456

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Nucleic acids
Nucleic Acids
Complementary RNA
Thermodynamic stability
Complementary DNA

LNA (Locked Nucleic Acids): Synthesis of Adenin, Cytosine, Guanine, 5-Methylcytosine, Thymine and Uracil Bicyclonucleoside Monomers, Oligomerisation, and Unprecedented Nucleic Acid Recognition

Koshkin, A. A., Singh, S. K., Nielsen, P., Rajwanshi, V. K., Kumar, R., Meldgaard, M., Olsen, C. E. & Wengel, J., 1998, I : Tetrahedron. 54, 14, s. 3607-3630

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

5-Methylcytosine
Oligomerization
Thymine
Uracil
Cytosine

Synthesis and chemoselective activation of phenyl 3,5-di-O-benzyl-2-O,4-C-methylene-1-thio-b-D-ribofuranoside: a key synthon towards a-LNA

Nielsen, P. & Wengel, J., 1998, I : Chemical Communications. 1998, 23, s. 2645-2646

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Chemical activation
Acids
2'-O-4'-C-methylene-ribofuranosyl nucleotide
Nucleosides

Synthesis of novel 3'-C-branched 2'-deoxynucleosides. Incorporation of 3'-C-(3-hydroxypropyl)thymidine into oligodeoxynucleotides

Pfundheller, H. M., Jørgensen, P. N., Sørensen, U. S., Sharma, S. K., Grimstrup, M., Ströch, C., Nielsen, P., Viswanadham, G., Olsen, C. E. & Wengel, J., 1998, I : Royal Chemical Society. Journal. Perkin Transactions 1. 1998, 8, s. 1409-1422

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Oligodeoxyribonucleotides
Thymidine
Glycosides
Monomers
Derivatives
1997

A novel class of conformationally restricted oligonucleotide analogues: synthesis of 2',3'-bridged monomers and RNA-selective hybridisation

Nielsen, P., Pfundheller, H. M. & Wengel, J., 1997, I : Chemical Communications. 1997, 9, s. 825-826

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Oligonucleotides
RNA
Nucleosides
Monomers

Synthesis and Evaluation of Novel Oligodeoxynucleotides Containing 3′-C-(3-Benzoyloxypropyl)thymidine and Bicyclo Nucleoside Derivatives

Pfundheller, H. M., Nielsen, P. & Wengel, J., 1997, I : Nucleosides, Nucleotides and Nucleic Acids. 16, 7-9, s. 1439-1442

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Oligodeoxyribonucleotides
Nucleosides
Thymidine
Derivatives
Monomers

Synthesis of 2'-O,3'-C-linked bicyclic nucleosides and bicyclic oligonucleotides

Nielsen, P., Pfundheller, H. M., Olsen, C. E. & Wengel, J., 1997, I : Royal Chemical Society. Journal. Perkin Transactions 1. 1997, 22, s. 3423-3434

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Nucleosides
Oligonucleotides
Complementary RNA
Thymine
Oligodeoxyribonucleotides
1996

Stereoselective Preparation of 3'-C-Allyluridines and 3'-Spiro-gamma-Lactone Uridine Analogues

Nielsen, P., Larsen, K. & Wengel, J., 1996, I : Acta Chemica Scandinavica. 50, 11, s. 1030-1035

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

1995

Evaluation of Oligonucleotides with Novel Modifications

Larsen, E., Danel, K., Abdel-Aleem, A-A. H., Nielsen, P., Wengel, J. & Pedersen, E. B., 1995, I : Nucleosides, Nucleotides and Nucleic Acids. 14, 3-5, s. 1097-1100

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Oligodeoxyribonucleotides
Nucleosides
Oligonucleotides
DNA

Synthesis and Evaluation of Oligodeoxynucleotides Containing Acyclic Nucleosides: Introduction of Three Novel Analogues and a Summary

Nielsen, P., Dreiøe, L. H. & Wengel, J., 1995, I : Bioorganic & Medicinal Chemistry. 3, 1, s. 19-28

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Oligodeoxyribonucleotides
Nucleosides
Degradation
Thymine
Oligomers
1994
spleen exonuclease
Oligodeoxyribonucleotides
Oligomers
Thymidine
Degradation