Peter Højrup

lic.scient.

  • Campusvej 55

    5230 Odense M

    Danmark

1982 …2020
Hvis du har foretaget ændringer i Pure, vil de snart blive vist her.

Publikationer 1982 2020

2020

Cannabidiol is an effective helper compound in combination with bacitracin to kill Gram-positive bacteria

Wassmann, C. S., Højrup, P. & Klitgaard, J. K., 19. feb. 2020, (Accepteret/In press) I : Scientific Reports.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Citrullinome of Porphyromonas gingivalis Outer Membrane Vesicles: Confident Identification of Citrullinated Peptides

Larsen, D. N., Mikkelsen, C. E., Kierkegaard, M., Bereta, G. P., Nowakowska, Z., Kaczmarek, J. Z., Potempa, J. & Højrup, P., jan. 2020, I : Molecular & cellular proteomics : MCP. 19, 1, s. 167-180 14 s.

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Porphyromonas gingivalis
Membranes
Peptides
Chronic Periodontitis
Periplasm
2019

An IgY-based immunoassay to evaluate the biomarker potential of the Tannerella forsythia virulence factor karilysin in human saliva

Skottrup, P. D., López, R., Ksiazek, M., Højrup, P., Baelum, V., Potempa, J. & Kaczmarek, J. Z., jun. 2019, I : Journal of Immunological Methods. 469, s. 26-32

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Saliva
Immunoassay
Periodontitis
Point-of-Care Systems
Surface Plasmon Resonance
94 Downloads (Pure)

Enhanced trypsin on a budget: Stabilization, purification and high-temperature application of inexpensive commercial trypsin for proteomics applications

Heissel, S., Frederiksen, S. J., Bunkenborg, J. & Højrup, P., 27. jun. 2019, I : PLOS ONE. 14, 6, 16 s., e0218374.

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Åben adgang
Fil
High temperature applications
proteomics
Trypsin
trypsin
Purification
111 Downloads (Pure)

Immunoglobulin G structure and rheumatoid factor epitopes

Maibom-Thomsen, S. L., Trier, N. H., Holm, B. E., Hansen, K. B., Rasmussen, M. I., Chailyan, A., Marcatili, P., Højrup, P. & Houen, G., 14. jun. 2019, I : PLOS ONE. 14, 6, 28 s., e0217624.

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Åben adgang
Fil
Rheumatoid Factor
immunoglobulin G
epitopes
Epitopes
Immunoglobulin G
2018

Chaperone-client interactions between Hsp21 and client proteins monitored in solution by small angle X-ray scattering and captured by crosslinking mass spectrometry

Rutsdottir, G., I Rasmussen, M., Hojrup, P., Bernfur, K., Emanuelsson, C. & Söderberg, C. A. G., 2018, I : Proteins. 86, 1, s. 110-123

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X ray scattering
Crosslinking
Mass spectrometry
X-Rays
Small Heat-Shock Proteins
65 Downloads (Pure)

Discrimination of Isoleucine and Leucine by Dimethylation-Assisted MS3

Maibom-Thomsen, S., Heissel, S., Mørtz, E., Højrup, P. & Bunkenborg, J., 2018, I : Analytical Chemistry. 90, 15, s. 9055–9059

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Åben adgang
Fil
Isoleucine
Leucine
Peptides
Ions
Thermolysin
78 Downloads (Pure)

Evaluation of spectral libraries and sample preparation for DIA-LC-MS analysis of host cell proteins: A case study of a bacterially expressed recombinant biopharmaceutical protein

Heissel, S., Bunkenborg, J., Kristiansen, M. P., Holmbjerg, A. F., Grimstrup, M., Mørtz, E., Kofoed, T. & Højrup, P., 2018, I : Protein Expression and Purification. 147, s. 69-77

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Åben adgang
Fil
Recombinant Proteins
Libraries
Proteins
Workflow
Isotopes
186 Downloads (Pure)

Structural modelling of the DNAJB6 oligomeric chaperone shows a peptide-binding cleft lined with conserved S/T-residues at the dimer interface

Söderberg, C. A. G., Månsson, C., Bernfur, K., Rutsdottir, G., Härmark, J., Rajan, S., Al-Karadaghi, S., Rasmussen, M., Höjrup, P., Hebert, H. & Emanuelsson, C., 2018, I : Scientific Reports. 8, 15 s., 5199.

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Åben adgang
Fil
Peptides
Isotopes
Lysine
Electron Microscopy
X-Rays
105 Downloads (Pure)

XK-related protein 5 (XKR5) is a novel negative regulator of KIT/D816V-mediated transformation

Sun, J., Thingholm, T., Højrup, P. & Rönnstrand, L., 18. jun. 2018, I : Oncogenesis. 7, 6, 11 s., 48.

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Åben adgang
Fil
Proteins
Tyrosine
Down-Regulation
2017

Characterization of equine vitamin D–binding protein, development of an assay, and assessment of plasma concentrations of the protein in healthy horses and horses with gastrointestinal disease

Pihl, T. H., Jacobsen, S., Olsen, D. T., Højrup, P., Grosche, A., Freeman, D. E., Andersen, P. H. & Houen, G., 2017, I : American Journal of Veterinary Research. 78, 6, s. 718-728

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Gastrointestinal Diseases
digestive system diseases
Vitamins
Horses
vitamins
124 Downloads (Pure)

Iron-induced oligomerization of human FXN81-210 and bacterial CyaY frataxin and the effect of iron chelators

Ahlgren, E. C., Fekry, M., Wiemann, M., Söderberg, C. A., Bernfur, K., Gakh, O., Rasmussen, M., Højrup, P., Emanuelsson, C., Isaya, G. & Al-Karadaghi, S., 2017, I : PLOS ONE. 12, 12, 25 s., e0188937.

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Åben adgang
Fil
Oligomerization
Chelating Agents
chelating agents
Oligomers
Iron
112 Downloads (Pure)

Structural model of dodecameric heat-shock protein Hsp21: Flexible N-terminal arms interact with client proteins while C-terminal tails maintain the dodecamer and chaperone activity

Rutsdottir, G., Härmark, J., Weide, Y., Hebert, H., Rasmussen, M. I., Wernersson, S., Respondek, M., Akke, M., Højrup, P., Koeck, P. J. B., Söderberg, C. A. G. & Emanuelsson, C., 2017, I : Journal of Biological Chemistry. 292, 19, s. 8103-8121

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Åben adgang
Fil
Small Heat-Shock Proteins
Heat-Shock Proteins
Protein C
Plant Structures
Oligomerization
2016

Exploring structure and interactions of the bacterial adaptor protein YjbH by crosslinking mass spectrometry

Al-Eryani, Y., Ib Rasmussen, M., Kjellström, S., Højrup, P., Emanuelsson, C. & von Wachenfeldt, C., sep. 2016, I : Proteins. 84, 9, s. 1234-1245

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Crosslinking
Mass spectrometry
Proteins
Peptide Hydrolases
Lysine

Mapping the Ca2+ induced structural change in calreticulin

Boelt, S. G., Norn, C., Rasmussen, M. I., André, I., Čiplys, E., Slibinskas, R., Houen, G. & Højrup, P., 16. jun. 2016, I : Journal of Proteomics. 142, s. 138-148

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Calreticulin
Reticulin
Reticulum
Peptides
Biological systems
2015

[(64) Cu]-labelled trastuzumab: optimisation of labelling by DOTA and NODAGA conjugation and initial evaluation in mice

Schjoeth-Eskesen, C., Nielsen, C. H., Heissel, S., Højrup, P., Hansen, P. R., Gillings, N. & Kjaer, A., 2015, I : Journal of Labelled Compounds and Radiopharmaceuticals. 58, 6, s. 227-33

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Labeling
Tumors
Chelating Agents
Trastuzumab
1-(1,3-carboxypropyl)-4,7-carboxymethyl-1,4,7-triazacyclononane

Agarose gel shift assay reveals that calreticulin favors substrates with a quaternary structure in solution

Boelt, S. G., Houen, G. & Højrup, P., 2015, I : Analytical Biochemistry. 481, s. 33-42

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Calreticulin
Sepharose
Assays
Gels
Substrates

Analysis of Peptides and Conjugates by Amino Acid Analysis

Højrup, P., 2015, Peptide Antibodies: Methods and Protocols. Houen, G. (red.). Humana Press, s. 65-76 (Methods in Molecular Biology, Bind 1348).

Publikation: Bidrag til bog/antologi/rapport/konference-proceedingBidrag til bog/antologiForskningpeer review

Amino Acids
Peptides
Ninhydrin
Ion Exchange Chromatography
Glutamine

Characterization of Synthetic Peptides by Mass Spectrometry

Prabhala, B. K., Mirza, O., Højrup, P. & Hansen, P. R., 2015, Peptide Antibodies: Methods and Protocols. Houen, G. (red.). Springer, Bind 1348. s. 77-82 (Methods in Molecular Biology).

Publikation: Bidrag til bog/antologi/rapport/konference-proceedingBidrag til bog/antologiForskningpeer review

Peptides
Matrix-Assisted Laser Desorption-Ionization Mass Spectrometry
Tandem Mass Spectrometry
131 Downloads (Pure)

High-level secretion of native recombinant human calreticulin in yeast

Čiplys, E., Žitkus, E., Gold, L. I., Daubriac, J., Pavlides, S. C., Højrup, P., Houen, G., Wang, W-A., Michalak, M. & Slibinskas, R., 2015, I : Microbial Cell Factories. 14, October, 14 s., 165.

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Åben adgang
Fil
Calreticulin
Yeast
Proteins
Recombinant proteins
Saccharomyces cerevisiae

Interpretation of Tandem Mass Spectrometry (MSMS) Spectra for Peptide Analysis

Hjernø, K. & Højrup, P., 2015, Peptide antibodies: methods and protocols. Humana Press, Bind 1348. s. 83-102 (Methods in Molecular Biology, Bind 1348).

Publikation: Bidrag til bog/antologi/rapport/konference-proceedingBidrag til bog/antologiFormidling

Tandem Mass Spectrometry
Peptides
Guidelines
2014

Characterization of an extensin-modifying metalloprotease: N-terminal processing and substrate cleavage pattern of Pectobacterium carotovorum Prt1

Feng, T., Nyffenegger, C., Højrup, P., Vidal-Melgosa, S., Yan, K-P., Fangel, J. U., Meyer, A. S., Kirpekar, F., Willats, W. G. & Mikkelsen, J. D., 2014, I : Applied Microbiology and Biotechnology. 98, s. 10077-10089

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Implications for the offspring of circulating factors involved in beta cell adaptation in pregnancy

Nalla, A., Ringholm, L., Søstrup, B., Højrup, P., Thim, L., Levery, S. B., Vakhrushev, S. Y., Billestrup, N., Mathiesen, E. R., Damm, P. & Nielsen, J. H., nov. 2014, I : Acta Obstetricia et Gynecologica Scandinavica. 93, 11, s. 1181-9 9 s.

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Serum
Pregnant Women
Hormones
Placental Lactogen
Peptides

Probing the structure of human protein disulfide isomerase by chemical cross-linking combined with mass spectrometry

Peng, L., Rasmussen, M. I., Chailyan, A., Houen, G. & Højrup, P., 2. maj 2014, I : Journal of Proteomics. 108, August, s. 1-16 16 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Protein Disulfide-Isomerases
Mass spectrometry
Calnexin
Proteins
Molecules

Proteomics of Fuchs' Endothelial Corneal Dystrophy support that the extracellular matrix of Descemet's membrane is disordered

Poulsen, E. T., Dyrlund, T. F., Runager, K., Scavenius, C., Krogager, T. P., Højrup, P., Thøgersen, I. B., Sanggaard, K. W., Vorum, H., Hjortdal, J. & Enghild, J. J., 2014, I : Journal of Proteome Research. 13, 11, s. 4659–4667

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Fuchs' Endothelial Dystrophy
Descemet Membrane
Membranes
Proteins
Tissue

Purification and characterization of bioactive his6-tagged recombinant human tissue inhibitor of metalloproteinases-1 (TIMP-1) protein expressed at high yields in mammalian cells

Vinther, L., Lademann, U., Andersen, E. V., Højrup, P., Thaysen-Andersen, M., Krogh, B. O., Viuff, B., Brünner, N., Stenvang, J. & Moreira, J. M. A., sep. 2014, I : Protein Expression and Purification. 101, s. 157-64 8 s.

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Tissue Inhibitor of Metalloproteinase-1
Proteins
Glycosylation
Matrix Metalloproteinase Inhibitors
HEK293 Cells
2013

Aluminum hydroxide adjuvant differentially activates the three complement pathways with major involvement of the alternative pathway

Güven, E., Duus, K., Laursen, I., Højrup, P. & Houen, G., 2013, I : PLOS ONE. 8, 9, s. e74445

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Aluminum Hydroxide
aluminum hydroxide
adjuvants
complement
Chemical activation

A Selected Reaction Monitoring (SRM)-Based Method for Absolute Quantification of Aβ38, Aβ40, and Aβ42 in Cerebrospinal Fluid of Alzheimer's Disease Patients and Healthy Controls

Pannee, J., Portelius, E., Oppermann, M., Atkins, A., Hornshaw, M., Zegers, I., Højrup, P., Minthon, L., Hansson, O., Zetterberg, H., Blennow, K. & Gobom, J., 2013, I : Journal of Alzheimer's Disease. 33, 4, s. 1021-1032

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Cerebrospinal Fluid
Alzheimer Disease
Research
Clinical Trials
Peptides

Glycopeptide Enrichment for MALDI-TOF Mass Spectrometry Analysis by Hydrophilic Interaction Liquid Chromatography Solid Phase Extraction (HILIC SPE)

Jensen, P. H., Mysling, S., Højrup, P. & Jensen, O. N., 2013, I : Methods in Molecular Biology. 951, s. 131-144

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Matrix-Assisted Laser Desorption-Ionization Mass Spectrometry
Solid Phase Extraction
Liquid Chromatography
Ions
Peptides

Identification of a laccase from Ganoderma lucidum CBS 229.93 having potential for enhancing cellulase catalyzed lignocellulose degradation

Sitarz, A. K., Mikkelsen, J. D., Højrup, P. & Meyer, A. S., 10. dec. 2013, I : Enzyme and Microbial Technology. 53, 6-7, s. 378-85

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Reishi
Sugar cane
Laccase
Bagasse
Cellulase

Proteomic profiling of Mycobacterium tuberculosis identifies nutrient-starvation-responsive toxin-antitoxin systems

Albrethsen, J., Agner, J., Piersma, S. R., Højrup, P., Pham, T. V., Weldingh, K., Jimenez, C. R., Andersen, P. & Rosenkrands, I., 2013, I : Molecular and Cellular Proteomics. 12, 5, s. 1180-1191

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Antitoxins
Mycobacterium tuberculosis
Nutrients
Food
Proteins

Purification and characterization of a soluble calnexin from human placenta

Olsen, D. T., Peng, L., Træholt, S. D., Duus, K., Højrup, P. & Houen, G., 2013, I : Protein Expression and Purification. 92, 1, s. 105-11

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Calnexin
Calreticulin
Placenta
Ion Exchange Chromatography
Protease Inhibitors

Serine Protease HtrA1 Accumulates in Corneal Transforming Growth Factor Beta Induced Protein (TGFBIp) Amyloid Deposits

Runager, K., Karring, H., Poulsen, E. T., Thøgersen, I. B., Klintworth, G. K., Højrup, P. & Enghild, J. J., 2013. 16 s.

Publikation: Konferencebidrag uden forlag/tidsskriftKonferenceabstrakt til konferenceForskningpeer review

Serine Protease HtrA1 Accumulates in Corneal Transforming Growth Factor Beta Induced Protein (TGFBIp) Amyloid Deposits

Runager, K., Karring, H., Poulsen, E. T., Thøgersen, I. B., Klintworth, G. K., Højrup, P. & Enghild, J. J., 17. sep. 2013.

Publikation: Konferencebidrag uden forlag/tidsskriftPosterForskningpeer review

Serine protease HtrA1 accumulates in corneal transforming growth factor beta induced protein (TGFBIp) amyloid deposits

Karring, H., Poulsen, E. T., Runager, K., Thøgersen, I. B., Klintworth, G. K., Højrup, P. & Enghild, J. J., 2013, I : Molecular Vision. 19, s. 861-76

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Towards the N-terminal acetylome: an N-terminal acetylated peptide enrichment method using CNBr-activated sepharose resin

Zhang, X. & Højrup, P., 2013, I : Methods in Molecular Biology. 981, s. 47-56

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Sepharose
Peptides
Proteome
Acetylation
Proteins
2012

A Single Rainbow Trout Cobalamin-binding Protein Stands in for Three Human Binders

Greibe, E. H., Fedosov, S., Sorensen, B. S., Højrup, P., Poulsen, S. S. & Nexo, E., 2012, I : Journal of Biological Chemistry. 287, 40, s. 33917-25 9 s.

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Transcobalamins
Oncorhynchus mykiss
Binders
Trout
Intrinsic Factor

COMPOSITION AND PROTEOLYTIC PROCESSING OF CORNEAL DEPOSITS ASSOCIATED WITH MUTATIONS IN THE TGFBI GENE

Karring, H., Poulsen, E. T., Runager, K., Klintworth, G. K., Højrup, P. & Enghild, J. J., 21. jul. 2012.

Publikation: Konferencebidrag uden forlag/tidsskriftKonferenceabstrakt til konferenceForskningpeer review

Composition and proteolytic processing of corneal deposits associated with mutations in the TGFBI gene

Karring, H., Runager, K., B. Thøgersen, I., K. Klintworth, G., Højrup, P. & Enghild, J. J., 2012, I : Experimental Eye Research. 96, 1, s. 163-170

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Identification of a potential biomarker panel for the intake of the common dietary trans fat elaidic acid (trans∆9-C18:1)

Krogager, T. P., Nielsen, L. V., Bak, S., Young, C., Ferreri, C., Jensen, O. N., Højrup, P., Thoma, V., Thøgersen, I. & Enghild, J. J., 2012, I : Journal of Proteomics. 75, 9, s. 2685-96 12 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Isotope Labeling
Dietary Fats
Biomarkers
Cell culture
Isotopes

Proteinase 3 carries small unusual carbohydrates and associates with αlpha-defensins

Zoega, M., Ravnsborg, T., Højrup, P., Houen, G. & Schou, C., 2012, I : Journal of Proteomics. 75, 5, s. 1472-1485

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Myeloblastin
Defensins
Carbohydrates
Neutrophils
Glycosylation

PROTEOMICS OF CORNEAL DYSTROPHIES

Poulsen, E. T., Karring, H., Runager, K., Dyrlund, T. F., Klintworth, G. K., Højrup, P., Otzen, D. & Enghild, J. J., 2012.

Publikation: Konferencebidrag uden forlag/tidsskriftKonferenceabstrakt til konferenceForskningpeer review

PROTEOMICS OF CORNEAL DYSTROPHIES

Poulsen, E. T., Karring, H., Runager, K., Dyrlund, T. F., Klintworth, G. K., Højrup, P., Otzen, D. & Enghild, J. J., 9. jul. 2012.

Publikation: Konferencebidrag uden forlag/tidsskriftPosterForskningpeer review

The protein composition of the digestive fluid from the Venus flytrap sheds light on prey digestion mechanisms.

Schulze, W. X., Sanggaard, K. W., Kreuzer, I., Knudsen, A. D., Bemm, F., Thøgersen, I. B., Bräutigam, A., Thomsen, L. R., Schliesky, S., Dyrlund, T. F., Escalante-Perez, M., Becker, D., Schultz, J., Karring, H., Weber, A., Højrup, P., Hedrich, R. & Enghild, J. J., 2012, I : Molecular and Cellular Proteomics. 11, 11, s. 1306-1319 14 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Time-dependent changes in protein expression in rainbow trout muscle following hypoxia

Wulff, T., Jokumsen, A., Højrup, P. & Jessen, F., 2012, I : Journal of Proteomics. 75, 8, s. 2342-51 10 s.

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Oncorhynchus mykiss
Muscle
Muscles
Proteins
Proteome
2011

3D Protein Structure Through Chemical Cross-linking, H/D exchange, Mass-spectrometry and Software-assisted Modelling

Rasmussen, M., Refsgaard, J., Amon, S., Peng, L., Jørgensen, T. J. D. & Højrup, P., 8. jun. 2011.

Publikation: Konferencebidrag uden forlag/tidsskriftPosterForskning

A model of the calreticulin complex with C1q

Boelt, S. G., Højrup, P. & Houen, G., 30. aug. 2011. 1 s.

Publikation: Konferencebidrag uden forlag/tidsskriftPosterForskning

Analysing the solution structure of calreticulin using hydrogen-deuterium exchange and bioinformatics

Rasmussen, M., Amon, S., Peng, L., Houen, G., Jørgensen, T. J. D. & Højrup, P., 30. aug. 2011. 1 s.

Publikation: Konferencebidrag uden forlag/tidsskriftPosterForskning

A proteome-scale study on in vivo protein N(α)-acetylation using an optimized method.

Zhang, X., Engholm-Keller, K. & Højrup, P., 2011, I : Proteomics. 11, s. 81-93 14 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

A proteome-scale study on in vivo protein Nα-acetylation using an optimized method

Zhang, X., Ye, J., Engholm-Keller, K. & Højrup, P., 1. jan. 2011, I : Proteomics. 11, 1, s. 81-93 13 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Acetylation
Proteome
Peptides
Resins
Proteins