Peter Højrup

lic.scient.

  • Campusvej 55

    5230 Odense M

    Danmark

1982 …2020
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Personlig profil

CV

Personal data:
Date & place of birth: 04-08-1953, Denmark
Address: Department of Biochemistry and Molecular Biology
University of Southern Denmark
Campusvej 55, DK-5230 Odense M
Contacts: php@bmb.sdu.dk; phone: +45 6550 2371

Academic degrees:
1986: PhD in Molecular Biology, Odense University
1982: MSc, Molecular Biology (major) and Chemistry (minor), The University of Aarhus

Employments:
2008-present: Professor MSO (Department of Biochemistry and Molecular Biology, University of Southern Denmark)
1991-2008: Associate Professor, (Department of Molecular Biology, Odense University, now University of Southern Denmark)
1989-1990: Postdoctoral fellow (Department of Molecular Biology, Odense University)
1988: Temporary Associate Professor (Dept. of Molecular Biology, Odense University)
1986-1988: Postdoctoral fellow (Department of Molecular Biology, Odense University)
1985-1986: Postdoctoral fellow (Department of Molecular Biology, Univ. of Aarhus)

Current research:
PHs research focuses on protein structure and function. A primary focus is the development of new methods for determining protein three-dimensional structure and protein interaction by chemical cross-linking followed by mass spectrometric determination of linkages. Another topic is the structure and function of the endoplasmatic proteins, in particular calreticulin and calnexin. Furthermore, development of methods for fast analysis of glycopeptides by mass spectrometry.

Specific topics
• Three-dimensional structure of calreticulin (mono, di- and multimers)
• Fast glycosylation analysis of immunoglobulins
• Glycopeptide quantitation
• Glycosylation analysis of cancer markers
• De novo proteomics of fish mucus proteins

Administrative experience:
2006-present: Ph.d. study leader, Faculty of Science, SDU

Editorial and reviewing tasks:
Editor for Journal of Proteomics.
Member of committees for appointments of assoc. and full Professorships in Denmark. Reviewer of grant proposals (Austria and Switzerland). Referee for a number of journals.

Supervision:
1 postdocs, 6 PhD students, 23 MSc students (4 Novo scholars; 1 Oticon) and 7 BSc students.

Congress organization:
Co-organizer of five conferences in Denmark on Mass spectrometry (2003-2006).

Fingeraftryk Fingeraftryk er baseret på at anvende teksten fra personernes videnskabelige dokumenter til at skabe et indeks med vægtede emneordskoncepter, som definerer de vigtigste emner for hver enkelt forsker.

  • 4 Lignende profiler
Proteins Medicin og biovidenskab
Peptides Medicin og biovidenskab
Calreticulin Medicin og biovidenskab
Mass spectrometry Kemiske forbindelser
Locusta migratoria Medicin og biovidenskab
Amino Acids Kemiske forbindelser
Glycosylation Medicin og biovidenskab
Diazepam Binding Inhibitor Medicin og biovidenskab

Netværk Nyligt eksternt samarbejde på landeniveau. Dyk ned i detaljerne ved at klikke på punkterne.

Publikationer 1982 2019

An IgY-based immunoassay to evaluate the biomarker potential of the Tannerella forsythia virulence factor karilysin in human saliva

Skottrup, P. D., López, R., Ksiazek, M., Højrup, P., Baelum, V., Potempa, J. & Kaczmarek, J. Z., jun. 2019, I : Journal of Immunological Methods. 469, s. 26-32

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Saliva
Immunoassay
Periodontitis
Point-of-Care Systems
Surface Plasmon Resonance
54 Downloads (Pure)

Enhanced trypsin on a budget: Stabilization, purification and high-temperature application of inexpensive commercial trypsin for proteomics applications

Heissel, S., Frederiksen, S. J., Bunkenborg, J. & Højrup, P., 27. jun. 2019, I : PLOS ONE. 14, 6, 16 s., e0218374.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Åben adgang
Fil
High temperature applications
proteomics
Trypsin
trypsin
Purification
65 Downloads (Pure)

Immunoglobulin G structure and rheumatoid factor epitopes

Maibom-Thomsen, S. L., Trier, N. H., Holm, B. E., Hansen, K. B., Rasmussen, M. I., Chailyan, A., Marcatili, P., Højrup, P. & Houen, G., 14. jun. 2019, I : PLOS ONE. 14, 6, 28 s., e0217624.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Åben adgang
Fil
Rheumatoid Factor
immunoglobulin G
epitopes
Epitopes
Immunoglobulin G

Chaperone-client interactions between Hsp21 and client proteins monitored in solution by small angle X-ray scattering and captured by crosslinking mass spectrometry

Rutsdottir, G., I Rasmussen, M., Hojrup, P., Bernfur, K., Emanuelsson, C. & Söderberg, C. A. G., 2018, I : Proteins. 86, 1, s. 110-123

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

X ray scattering
Crosslinking
Mass spectrometry
X-Rays
Small Heat-Shock Proteins
29 Downloads (Pure)

Discrimination of Isoleucine and Leucine by Dimethylation-Assisted MS3

Maibom-Thomsen, S., Heissel, S., Mørtz, E., Højrup, P. & Bunkenborg, J., 2018, I : Analytical Chemistry. 90, 15, s. 9055–9059

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Åben adgang
Fil
Isoleucine
Leucine
Peptides
Ions
Thermolysin

Aktiviteter 2007 2013

Cross-linking human protein disulfide isomerase: what to do with a thousand cross-links?

Peter Højrup (Foredragsholder)
21. nov. 2013

Aktivitet: Foredrag og mundtlige bidragForedrag og præsentationer i privat eller offentlig virksomhed

MONOCLONAL PROTEINASE 3 ANTIBODIES BINDING AT THE ACTIVE SITE

Peter Højrup (Foredragsholder)
13. maj 2012

Aktivitet: Foredrag og mundtlige bidragForedrag og præsentationer i privat eller offentlig virksomhed

Proteomics in Nutritional Research: A 2-DE based study of diet induced changes in the human plasma proteome

Peter Højrup (Eksaminator)
11. dec. 2011

Aktivitet: Censoraktivitet og eksamineringIntern eksaminator

Structure determination of human calreticulin by chemical cross-linking and mass spectrometry

Peter Højrup (Foredragsholder)
9. dec. 2011

Aktivitet: Foredrag og mundtlige bidragForedrag og præsentationer i privat eller offentlig virksomhed

Methods (Tidsskrift)

Peter Højrup (Peer reviewer)
21. nov. 2011

Aktivitet: Redaktionelt arbejde og fagfællebedømmelsePeer reviewer/fagfællebedømmer af manuskripterForskning

Projekter 2001 2020

Presse/medie

Respekt!

Peter Højrup

05/10/2018

1 Mediebidrag

Presse/medie