Current position

Biostatistician, Department of Nuclear Medicine, Odense University Hospital & Professor with specific responsibilities in clinical biostatistics in diagnostic research, Department of Clinical Research, University of Southern Denmark

Former positions

2011-18 Associate Professor (20%), Dep. of Business and Economics, SDU

2006 Senior Statistician, Early Clinical Development, Novartis Pharma AG, Basel

2002-06 Biometrician, Clinical Statistics Europe, Schering AG, Berlin

2001/02 Junior Specialist, Information Resources GfK GmbH, Nürnberg

Scientific focus area

Design, analysis, and reporting of diagnostic and prognostic trials in molecular imaging

---- Response evaluation -----

** Gerke O et al. PET/CT-based response evaluation in cancer – a systematic review of design issues. Mol Imaging Biol. In press. https://rdcu.be/byrOE (Author’s Accepted Manuscript: https://www.ogy.dk)

** Vach W, Høilund-Carlsen PF, Fischer BM, Gerke O, Weber W. How to study optimal timing of PET/CT for monitoring of cancer treatment. Am J Nucl Med Mol Imaging. 2011;1(1):54-62. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3477720

----- Sequential and adaptive trial designs in diagnostic research -----

**Zapf A et al. Adaptive trial designs in diagnostic accuracy research. Stat Med. ePub ahead of print. https://onlinelibrary.wiley.com/doi/10.1002/sim.8430

** Gerke O et al. Group-sequential analysis may allow for early trial termination: illustration by an intra-observer repeatability study. EJNMMI Res. 2017;7:79.  http://rdcu.be/wd5R

----- Agreement -----

** Gerke O et al. Experience Applying the Guidelines for Reporting Reliability and Agreement Studies (GRRAS) Indicated Five Questions Should Be Addressed in the Planning Phase from a Statistical Point of View. Diagnostics (Basel). 2018;8(4):69. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316756/

** Gerke O et al. How to assess intra- and inter-observer agreement with quantitative PET using variance component analysis: a proposal for standardization. BMC Med Imaging. 2016;16:54. http://rdcu.be/nhN5

Co-advisor of ongoing PhD projects: 4

Co-advisor of completed PhD projects: 16

Main supervision of completed master theses: 6

Teaching: BSc and MSc level

Odense, 28 November 2019