Publikationer pr. år
Personlig profil
CV
CONTACT
Website www.gigtforskning.dk
E-mail kontakt@gigtforskning.dk
EDUCATION
June 2013 MSc in Medicine, Aarhus University, DK.
CURENT AND MOST RECENT POSITIONS HELD
Oct 2016- PhD fellow at the University of Southern Denmark/Dept. of Rheumatology, Odense University Hospital: “Gut and microbiota in arthritis and inflammatory rheumatic diseases - the GMARD project” Main Supervisor: Prof Torkell Ellingsen. Co-supervisors: Prof Jens Kjeldsen, ass. prof. Ulrich Fredberg, ass. prof. Robin Christensen, Jens Kristian Pedersen.
2016 and 2018 Maternity leaves.
2015 Union representative (TR), the Danish Medical Association, Diagnostic Centre, Silkeborg Regional Hospital.
2014-15 Jr. registrar, Diagnostic Centre, Silkeborg Regional Hospital.
2013-14 Educational coordinator for young doctors, Emergency Dept., Hospital Unit of Horsens.
RESEARCH FOCUS AREA
My research primarily focuses on the interplay between the human microbiota and autoimmune/inflammatory diseases (rheumatic diseases in particularly), and how the microbiota compositions can be used as diagnostic biomarkers and drug response predictors. Also, whether microbiota manipulation can be a future treatment for inflammatory diseases.
CURRENT RESEARCH PROJECTS including PhD studies and planned postdoc projects:
I. the FLORA trial "Efficacy and safety of faecal microbiota transplantation in patients with psoriatic arthritis: a 6-month, double-blind, randomised placebo-controlled trial.” Trial reg.no: NCT03058900. II. the FRONT pilots “Clinical aspects associated with faecal microbiota transplantation in patients with new-onset treatment-naïve rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, reactive arthritis, sarcoid arthritis, Crohn’s disease, and ulcerative colitis: A pilot trial.” III. IMPAACT “Immune-competent cell manifestations in psoriatic arthritis Achilles tendons: A prospective cohort-study.” Trial reg.no: NCT03248284. IV. The psoriatic arthritis epidemiology package (PAEP) “Prevalence and mortality risks of gut and lung diseases in psoriatic arthritis: A prospective population-based cohort study.”SUPERVISOR RESPONSIBILITIES
2018- Supervisor for Shaun Theodor Sødergren, Stud.Scient.San.Publ.: ”A qualitative study of potential side effects and patient experiences in relation to participation in a FMT trial for psoriatic arthritis.”
SCIENTIFIC AWARDS AND DEGREES
2013 Student Research Award, the Danish Rheumatism Association.
2012 Medical student research year dissertation:"Immunohistochemical Quantification of Macrophages, T and B-lymphocytes, Natural Killer, and Mast Cells in Biopsies from 56 non-ruptured Chronic tendinopathic Achilles Tendons." Main supervisor: Torkell Ellingsen. Co-supervisors: Ulrich Fredberg and Knud Bendix.
PEER-REVIEWED PUBLICATIONS
Kragsnaes MS, Kjeldsen J, Horn HC, Munk HL, Pedersen FM, Holt HM, Pedersen JK, Holm DK, Glerup H, Andersen V, Fredberg U, Kristiansen K, Christensen R, Ellingsen T. Efficacy and safety of faecal microbiota transplantation in patients with psoriatic arthritis: protocol for a 6-month, double-blind, randomised, placebo-controlled trial. BMJ Open.2018 Apr 27;8(4):e019231.
Kragsnaes MS, Fredberg U, Stribolt K, Kjaer SG, Bendix K, Ellingsen T. Stereological Quantification of Immune-competent Cells in Baseline Biopsy Specimens from Achilles tendons: Results from Patients with Chronic Tendinopathy Followed for more than 4 Years. Am J Sports Med. 2014;42:2435-2445.
INTERNATIONAL PRESENTATIONS
2014 Annual European Congress of Rheumatology, Paris (EULAR14-0382).
2012 Congress of American College of Rheumatology, Washington (ACR12-1877).
2012 Annual European Congress of Rheumatology, Berlin (EULAR12-2433).
NATIONAL PRESENTATIONS
Dec 2018 OUH talks. Fæces-mikrobiota-transplantation - et nyt behandlingstilbud på OUH (video link: http://ouhtalks.dk/wm509347)
Oct 2017 The Rheumatism Association. Psoriatic arthritis and the role of the intestinal microbiota.
Sept 2017 The Psoriasis Association: Psoriatic arthritis and the role of the intestinal microbiota.
April 2017 The Psoriasis Association: Psoriatic arthritis and the role of the intestinal microbiota.
Jan 2017 The Psoriasis Association: Psoriatic arthritis and the role of the intestinal microbiota.
Oct 2016 The Danish Association of Rheumatology Highlights: Fecal Microbiome Transplantation - A New Treatment in Rheumatology?
BOARDS AND SCIENTIFIC SOCIETIES
2018- Member of the assessment committee of Odense University Hospital’s research council.
2014- Member of the Danish Association of Rheumatology.
CONGRESSES, SYMPOSIA, CLINICAL COURSES AND CERTIFICATIONS
2016 Symposium on Gut Microbiota and Health, Novo Nordisk Foundation.
2015 Sports Medicine level 1 (40 CME point), the Danish Association of Sports Medicine.
2014 Certified in point-of-care clinical ultrasound (FATE, FAST, LUS), Center of Clinical Ultrasound.
2012 Congress of American College of Rheumatology, Washington.
2012 Annual European Congress of Rheumatology, Berlin.
2012 Congress for Medical Student Research, Denmark.
GRANT RECORD related to the PhD project:
2017: Vilhelm Pedersen og Hustrus Legat (Novo Nordisk Foundation). 1.000.000 DKK.
2017: AP Møller Foundation. 75.000 DKK.
2017: Odense University Hospital Research Fund. 75.000 DKK.
2017: The Psoriasis Foundation. 80.000 DKK.
2017: The Danish Rheumatism Association. 50.000 DKK.
2016: Odense University Hospital Research Fund. 100.000 DKK.
2016: The Danish Rheumatism Association. 70.000 DKK.
2016: Medicinpuljen, Danish Regions. 565.000 DKK.
2016: Region of Southern Denmark Research Foundation. 649.535 DKK.
2016: Odense University Hospital PhD fund. 500.000 kr.
2015: University of Southern Denmark faculty scholarship. 500.000 DKK.
2015: Odense University Hospital, OPEN. 100.000 DKK.
2015: The Danish Rheumatism Association scholarship. 250.000 DKK.
2015: The Danish Rheumatism Association. 63.000 DKK.
2015: The Psoriasis Foundation. 100.000 DKK.
Forskningsinformation
Forskningsområder
- Klinisk immunologi
- Gigtsygdomme
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Publikationer 2014 2018
Efficacy and safety of faecal microbiota transplantation in patients with psoriatic arthritis: protocol for a 6-month, double-blind, randomised, placebo-controlled trial
Kragsnaes, M. S., Kjeldsen, J., Horn, H. C., Munk, H. L., Pedersen, F. M., Holt, H. M., Pedersen, J. K., Holm, D. K., Glerup, H., Andersen, V., Fredberg, U., Kristiansen, K., Christensen, R. & Ellingsen, T., 1. apr. 2018, I : BMJ Open. 8, 4, 15 s., e019231.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
Establishing a fecal microbiota transplant service within the blood- and tissue transplant service in the region of Southern Denmark
Holm, D. K., Skov Kragsnæs, M., Nilsson, A. C., Kjeldsen, J., Ellingsen, T. J., Juel, M. A., Holt, H. M., Lillevang, S. T. & Georgsen, J., 2. jun. 2018.Publikation: Konferencebidrag uden forlag/tidsskrift › Poster › Forskning › peer review
Stereological quantification of immune-competent cells in baseline biopsy specimens from achilles tendons: results from patients with chronic tendinopathy followed for more than 4 years
Kragsnaes, M. S., Fredberg, U., Stribolt, K., Kjaer, S. G., Bendix, K. & Ellingsen, T., 2014, I : American Journal of Sports Medicine. 42, 10, s. 2435-45Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review