• Campusvej 55

    5230 Odense M

    Danmark

19982021

Research output per year

Hvis du har foretaget ændringer i Pure, vil de snart blive vist her.

Publikationer

2020

Identification of the initial molecular changes in response to circulating angiogenic cells-mediated therapy in critical limb ischemia

Beltran-Camacho, L., Jimenez-Palomares, M., Rojas-Torres, M., Sanchez-Gomar, I., Rosal-Vela, A., Eslava-Alcon, S., Perez-Segura, M. C., Serrano, A., Antequera-González, B., Alonso-Piñero, J. A., González-Rovira, A., Extremera-García, M. J., Rodriguez-Piñero, M., Moreno-Luna, R., Larsen, M. R. & Durán-Ruiz, M. C., 6. mar. 2020, I : Stem Cell Research and Therapy. 11, 1, 106.

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2019

Ageing and amyloidosis underlie the molecular and pathological alterations of tau in a mouse model of familial Alzheimer’s disease

Metaxas, A., Thygesen, C., Kempf, S. J., Anzalone, M., Vaitheeswaran, R., Petersen, S., Landau, A. M., Audrain, H., Teeling, J. L., Darvesh, S., Brooks, D. J., Larsen, M. R. & Finsen, B., 31. okt. 2019, I : Scientific Reports. 9, 1, 15 s., 15758.

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A Systems-level Characterization of the Differentiation of Human Embryonic Stem Cells into Mesenchymal Stem Cells

Billing, A. M., Dib, S. S., Bhagwat, A. M., da Silva, I. T., Drummond, R. D., Hayat, S., Al-Mismar, R., Ben-Hamidane, H., Goswami, N., Engholm-Keller, K., Larsen, M. R., Suhre, K., Rafii, A. & Graumann, J., 1. okt. 2019, I : Molecular and Cellular Proteomics. 18, 10, s. 1950-1966

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Cellular and molecular abnormalities in brain organoids derived from autistic patients

Ilieva, M., Kamand, M., Forsberg, S. L., Larsen, M. R. & Tanja, M., dec. 2019, I : European Neuropsychopharmacology. 29, Suppl. 6, s. S359-S360 P.510.

Publikation: Bidrag til tidsskriftKonferenceabstrakt i tidsskriftForskningpeer review

First-trimester proteomic profiling identifies novel predictors of gestational diabetes mellitus

Ravnsborg, T., Svaneklink, S., Andersen, L. L. T., Larsen, M. R., Jensen, D. M. & Overgaard, M., 27. mar. 2019, I : PLOS ONE. 14, 3, 13 s., e0214457.

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Integrated proteomics reveals apoptosis-related mechanisms associated with placental malaria

Kawahara, R., Rosa-Fernandes, L., Dos Santos, A. F., Bandeira, C. L., Dombrowski, J. G., Souza, R. M., da Fonseca, M. P., Festuccia, W. T., Labriola, L., Larsen, M. R., Marinho, C. R. F. & Palmisano, G., 1. feb. 2019, I : Molecular and Cellular Proteomics. 18, 2, s. 182-199

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PARK2 Mutation Causes Metabolic Disturbances and Impaired Survival of Human iPSC-Derived Neurons

Bogetofte Thomasen, H., Jensen, P., Ryding, M. A. J. G., Schmidt, S. I., Okarmus, J., Ritter, L., Worm, C. S., Hohnholt, M., Azevedo, C., Roybon, L., Bak, L. K., Waagepetersen, H. S., Ryan, B. J., Wade-Martins, R., Larsen, M. R. & Meyer, M., 5. jul. 2019, I : Frontiers in Cellular Neuroscience. 13, 14 s., 297.

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Perturbations in RhoA signalling cause altered migration and impaired neuritogenesis in human iPSC-derived neural cells with PARK2 mutation

Bogetofte, H., Jensen, P., Okarmus, J., Schmidt, S. I., Agger, M., Ryding, M., Nørregaard, P., Fenger, C., Zeng, X., Graakjær, J., Ryan, B. J., Wade-Martins, R., Larsen, M. R. & Meyer, M., dec. 2019, I : Neurobiology of Disease. 132, 14 s., 104581.

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Proteomic Analysis of Restored Insulin Production and Trafficking in Obese Diabetic Mouse Pancreatic Islets following Euglycemia

Kang, T., Boland, B. B., Alarcon, C., Grimsby, J. S., Rhodes, C. J. & Larsen, M. R., 6. sep. 2019, I : Journal of Proteome Research. 18, 9, s. 3245-3258

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Proteomic profiling of mouse epididymosomes reveals their contributions to post-testicular sperm maturation

Nixon, B., De Iuliis, G. N., Hart, H. M., Zhou, W., Mathe, A., Bernstein, I., Anderson, A. L., Stanger, S. J., Skerrett-Byrne, D. A., Jamaluddin, M. F. B., Almazi, J. G., Bromfield, E. G., Larsen, M. R. & Dun, M. D., 15. mar. 2019, I : Molecular and Cellular Proteomics. 18, Suppl. 1, s. S91-S108

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Proteomic signatures of neuroinflammation in Alzheimer's disease, multiple sclerosis and ischemic stroke

Thygesen, C., Larsen, M. R. & Finsen, B., jul. 2019, I : Expert Review of Proteomics. 16, 7, s. 601-611

Publikation: Bidrag til tidsskriftReviewForskningpeer review

Proteomics insights into the responses of Saccharomyces cerevisiae during mixed-culture alcoholic fermentation with Lachancea thermotolerans

Peng, C., Andersen, B., Arshid, S., Larsen, M. R., Albergaria, H., Lametsch, R. & Arneborg, N., sep. 2019, I : FEMS Microbiology Ecology. 95, 9, 16 s.

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Zika virus impairs neurogenesis and synaptogenesis pathways in human neural stem cells and neurons

Rosa-Fernandes, L., Cugola, F. R., Russo, F. B., Kawahara, R., de Melo Freire, C. C., Leite, P. E. C., Bassi Stern, A. C., Angeli, C. B., de Oliveira, D. B. L., Melo, S. R., Zanotto, P. M. D. A., Durigon, E. L., Larsen, M. R., Beltrão-Braga, P. C. B. & Palmisano, G., 15. mar. 2019, I : Frontiers in cellular neuroscience. 13, 16 s., 64.

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2018

Affinity proteomics for interactome and phosphoproteome screening in synaptosomes

Engholm-Keller, K., Bache, N., Rao, S. R., Wark, J. R., Larsen, M. R., Robinson, P. J. & Graham, M. E., sep. 2018, Synaptosomes. M. Murphy, K. (red.). Humana Press, Bind 141. s. 165-191 (Neuromethods, Bind 141).

Publikation: Bidrag til bog/antologi/rapport/konference-proceedingBidrag til bog/antologiForskningpeer review

Age-Dependent Changes in the Sarkosyl-Insoluble Proteome of APPSWE/PS1ΔE9 Transgenic Mice Implicate Dysfunctional Mitochondria in the Pathogenesis of Alzheimer's Disease

Thygesen, C., Metaxas, A., Larsen, M. R. & Finsen, B., 1. jan. 2018, I : Journal of Alzheimer's disease : JAD. 64, 4, s. 1247-1259

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

A Targeted LC-MS Strategy for Low-Abundant HLA Class-I-Presented Peptide Detection Identifies Novel Human Papillomavirus T-Cell Epitopes

Blatnik, R., Mohan, N., Bonsack, M., Falkenby, L. G., Hoppe, S., Josef, K., Steinbach, A., Becker, S., Nadler, W. M., Rucevic, M., Larsen, M. R., Salek, M. & Riemer, A. B., jun. 2018, I : Proteomics. 18, 11, 9 s., 1700390.

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Author Correction: Snake Venom Extracellular vesicles (SVEVs) reveal wide molecular and functional proteome diversity

Carregari, V. C., Rosa-Fernandes, L., Baldasso, P., Bydlowski, S. P., Marangoni, S., Larsen, M. R. & Palmisano, G., 23. okt. 2018, I : Scientific Reports. 8, 1 s., 15908.

Publikation: Bidrag til tidsskriftKommentar/debatForskningpeer review

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Characterization of Macrophage Endogenous S-Nitrosoproteome Using a Cysteine-Specific Phosphonate Adaptable Tag in Combination with TiO2 Chromatography

Ibáñez-Vea, M., Huang, H., Martínez De Morentin, X., Pérez, E., Gato, M., Zuazo, M., Arasanz, H., Fernández-Irigoyen, J., Santamaría, E., Fernandez-Hinojal, G., Larsen, M. R., Escors, D. & Kochan, G., 2018, I : Journal of Proteome Research. 17, 3, s. 1172-1182

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Characterizing disease-associated changes in post-translational modifications by mass spectrometry

Thygesen, C., Boll, I., Finsen, B., Modzel, M. & Larsen, M. R., 2018, I : Expert Review of Proteomics. 15, 3, s. 245-258

Publikation: Bidrag til tidsskriftReviewForskningpeer review

Development of a Neo-Epitope Specific Assay for Serological Assessment of Type VII Collagen Turnover and Its Relevance in Fibroproliferative Disorders

Sand, J. M. B., Lamy, P., Juhl, P., Siebuhr, A. S., Iversen, L. V., Nawrocki, A., Larsen, M. R., Domsic, R. T., Franchimont, N., Chavez, J., Karsdal, M. A. & Leeming, D. J., 2018, I : ASSAY and Drug Development Technologies. 16, 2, s. 123-131

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Development of a Trypanosoma cruzi strain typing assay using MS2 peptide spectral libraries (Tc-STAMS2)

de Oliveira, G. S., Kawahara, R., Rosa-Fernandes, L., Mule, S. N., Avila, C. C., Teixeira, M. M. G., Larsen, M. R. & Palmisano, G., 2018, I : PLOS Neglected Tropical Diseases . 12, 4, e0006351.

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Distinct urinary glycoprotein signatures in prostate cancer patients

Kawahara, R., Ortega, F., Rosa-Fernandes, L., Guimarães, V., Quina, D., Nahas, W., Schwämmle, V., Srougi, M., Leite, K. R. M., Thaysen-Andersen, M., Larsen, M. R. & Palmisano, G., 4. sep. 2018, I : Oncotarget. 9, 69, s. 33077-33097

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Diverse protein profiles in CNS myeloid cells and CNS tissue from lipopolysaccharide- and vehicle-injected APPSWE/PS1ΔE9 transgenic mice implicate cathepsin Z in alzheimer’s disease

Thygesen, C., Ilkjær, L., Kempf, S. J., Hemdrup, A. L., von Linstow, C. U., Babcock, A. A., Darvesh, S., Larsen, M. R. & Finsen, B., nov. 2018, I : Frontiers in cellular neuroscience. 12, 21 s., 397.

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Dynamic Changes in the Protein Localization in the Nuclear Environment in Pancreatic β-Cell after Brief Glucose Stimulation

Kang, T., Jensen, P., Solovyeva, V., Brewer, J. R. & Larsen, M. R., 6. apr. 2018, I : Journal of Proteome Research. 17, 4, s. 1664–1676

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Experimental demyelination and axonal loss are reduced in MicroRNA-146a deficient mice

Martin, N. A., Molnar, V., Szilagyi, G. T., Elkjaer, M. L., Nawrocki, A., Okarmus, J., Wlodarczyk, A., Thygesen, E. K., Palkovits, M., Gallyas, F., Larsen, M. R., Lassmann, H., Benedikz, E., Owens, T., Svenningsen, A. F. & Illes, Z., 2018, I : Frontiers in Immunology. 9, 14 s., 490.

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Extracellular vesicles with altered tetraspanin CD9 and CD151 levels confer increased prostate cell motility and invasion

Brzozowski, J. S., Bond, D. R., Jankowski, H., Goldie, B. J., Burchell, R., Naudin, C., Smith, N. D., Scarlett, C. J., Larsen, M. R., Dun, M. D., Skelding, K. A. & Weidenhofer, J., 11. jun. 2018, I : Scientific Reports. 8, 13 s., 8822.

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How many human proteoforms are there?

Aebersold, R., Agar, J. N., Amster, I. J., Baker, M. S., Bertozzi, C. R., Boja, E. S., Costello, C. E., Cravatt, B. F., Fenselau, C., Garcia, B. A., Ge, Y., Gunawardena, J., Hendrickson, R. C., Hergenrother, P. J., Huber, C. G., Ivanov, A. R., Jensen, O. N., Jewett, M. C., Kelleher, N. L., Kiessling, L. L. & 33 flere, Krogan, N. J., Larsen, M. R., Loo, J. A., Ogorzalek Loo, R. R., Lundberg, E., MacCoss, M. J., Mallick, P., Mootha, V. K., Mrksich, M., Muir, T. W., Patrie, S. M., Pesavento, J. J., Pitteri, S. J., Rodriguez, H., Saghatelian, A., Sandoval, W., Schlüter, H., Sechi, S., Slavoff, S. A., Smith, L. M., Snyder, M. P., Thomas, P. M., Uhlén, M., Van Eyk, J. E., Vidal, M., Walt, D. R., White, F. M., Williams, E. R., Wohlschlager, T., Wysocki, V. H., Yates, N. A., Young, N. L. & Zhang, B., 14. feb. 2018, I : Nature Chemical Biology. 14, 3, s. 206-214

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NS1 codon usage adaptation to humans in pandemic Zika virus

Freire, C. C. D. M., Palmisano, G., Braconi, C. T., Cugola, F. R., Russo, F. B., Beltrão-Braga, P. C. B., Iamarino, A., de Lima Neto, D. F., Sall, A. A., Rosa-Fernandes, L., Larsen, M. R. & Zanotto, P. M. D. A., 2018, I : Memórias do Instituto Oswaldo Cruz. 113, 5, e170385.

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Omics-based approach reveals complement-mediated inflammation in chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS)

Blaabjerg, M., Hemdrup, A. L., Drici, L., Ruprecht, K., Garred, P., Höftberger, R., Kristensen, B. W., Kondziella, D., Sejbaek, T., Hansen, S. W., Nielsen, H. H., Jensen, P., Meyer, M., Paul, F., Lassmann, H., Larsen, M. R. & Illes, Z., 2018, I : Frontiers in Immunology. 9, 13 s., 741.

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Orthologous proteins of experimental de- and remyelination are differentially regulated in the CSF proteome of multiple sclerosis subtypes

Martin, N. A., Nawrocki, A., Molnar, V., Elkjaer, M. L., Thygesen, E. K., Palkovits, M., Acs, P., Sejbaek, T., Nielsen, H. H., Hegedus, Z., Sellebjerg, F., Molnar, T., Barbosa, E. G. V., Alcaraz, N., Gallyas, F., Svenningsen, A. F., Baumbach, J., Lassmann, H., Larsen, M. R. & Illes, Z., 2018, I : PLOS ONE. 13, 8, s. 1-26 e0202530.

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Phosphoproteomic Analysis of Murine Hepatocytes Reveals Novel Targets of Hepatic Glucagon Action

Boland, M. L., Nawrocki, A., Mather, K., Jain, M., Jermutus, L., Larsen, M. R., Rhodes, C. J. & Trevaskis, J., okt. 2018, I : Hepatology. 68, Suppl. 1, s. 1018A 1 s., 1790.

Publikation: Bidrag til tidsskriftKonferenceabstrakt i tidsskriftForskning

Quantitative Proteomics and Phosphoproteomics Analysis Revealed Different Regulatory Mechanisms of Halothane and Rendement Napole Genes in Porcine Muscle Metabolism

Huang, H., Scheffler, T. L., Gerrard, D. E., Larsen, M. R. & Lametsch, R., 3. aug. 2018, I : Journal of Proteome Research. 17, 8, s. 2834-2849

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SILAC-based phosphoproteomics reveals new PP2A-Cdc55-regulated processes in budding yeast

Baro, B., Játiva, S., Calabria, I., Vinaixa, J., Bech-Serra, J-J., de LaTorre, C., Rodrigues, J., Hernáez, M. L., Gil, C., Barceló-Batllori, S., Larsen, M. R. & Queralt, E., 2018, I : GigaScience. 7, 5, 18 s., giy047.

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Snake Venom Extracellular vesicles (SVEVs) reveal wide molecular and functional proteome diversity

Carregari, V. C., Rosa-Fernandes, L., Baldasso, P., Bydlowski, S. P., Marangoni, S., Larsen, M. R. & Palmisano, G., 2018, I : Scientific Reports. 8, 1, s. 1-16 12067.

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2017

Alterations in the Cerebral Microvascular Proteome Expression Profile After Transient Global Cerebral Ischemia in Rat

Spray, S., Johansson, S. E., Edwards, A. V. G., Larsen, M. R., Radziwon-Balicka, A., Povlsen, G. K. & Edvinsson, L., 2017, I : Journal of Molecular Neuroscience. 61, 3, s. 396–411

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Characterization of the phosphoproteome and sialoproteome in brain tissues by mass spectrometry

Ibáñez-Vea, M., Kempf, S. J. & Larsen, M. R., 2017, Current Proteomic Approaches Applied to Brain Function. Santamaría, E. & Fernández-Irigoyen, J. (red.). Humana Press, s. 191-206 (Neuromethods, Bind 127).

Publikation: Bidrag til bog/antologi/rapport/konference-proceedingBidrag til bog/antologiForskningpeer review

Comprehensive glycoprofiling of the epimastigote and trypomastigote stages of Trypanosoma cruzi

Alves, M. J. M., Kawahara, R., Viner, R., Colli, W., Mattos, E. C., Thaysen-Andersen, M., Larsen, M. R. & Palmisano, G., 16. jan. 2017, I : Journal of Proteomics. 151, s. 182-192

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Convergent Akt activation drives acquired EGFR inhibitor resistance in lung cancer

Jacobsen, K., Bertran-Alamillo, J., Molina, M. A., Teixidó, C., Karachaliou, N., Pedersen, M. H., Castellví, J., Garzón, M., Codony-Servat, C., Codony-Servat, J., Giménez-Capitán, A., Drozdowskyj, A., Viteri, S., Larsen, M. R., Lassen, U., Felip, E., Bivona, T. G., Ditzel, H. J. & Rosell, R., 1. dec. 2017, I : Nature Communications. 8, 14 s., 410.

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Elucidation of altered pathways in tumor-initiating cells of triple-negative breast cancer: A useful cell model system for drug screening

Christensen, A. G., Ehmsen, S., Terp, M. G., Batra, R., Alcaraz, N., Baumbach, J., Noer, J. B., Moreira, J. M. A., Leth-Larsen, R., Larsen, M. R. & Ditzel, H. J., aug. 2017, I : Stem Cells. 35, 8, s. 1898–1912

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GLYCOSYLATED YGHJ POLYPEPTIDES FROM ENTEROTOXIGENIC ESCHERICHIA COLI (ETEC)

Boysen, A., Møller-Jensen, J., Palmisano, G. & Larsen, M. R., 13. apr. 2017, Patentnr. WO2017059864 (A1), 13. apr. 2017, Prioritetsdato 6. okt. 2015, Prioritetsnr. EP20150188608

Publikation: Patent

"Highly increased expression of astrocytic cytokine in neocortex of Alzheimer’s patients investigated by proteomics"

Thygesen, C., Kempf, S., Metaxas, A., Darvesh, S., Larsen, M. R. & Finsen, B., 2017.

Publikation: Konferencebidrag uden forlag/tidsskriftPosterForskningpeer review

Novel DNA coding regions and protein arginylation reveal unexplored T. cruzi proteome and PTMs

de Oliveira, G. S., Kawahara, R., Rosa-Fernandes, L., Avila, C. C., Larsen, M. R., Pereira Alves, J. M. & Palmisano, G., 2017, I : International Journal of Mass Spectrometry. 418, s. 51-66

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Proteomic Expression Changes in Large Cerebral Arteries After Experimental Subarachnoid Hemorrhage in Rat Are Regulated by the MEK-ERK1/2 Pathway

Müller, A. H., Edwards, A. V. G., Larsen, M. R., Nielsen, J., Warfvinge, K., Povlsen, G. K. & Edvinsson, L., 2017, I : Journal of Molecular Neuroscience. 62, 3-4, s. 380-394

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TNFα affects CREB-mediated neuroprotective signaling pathways of synaptic plasticity in neurons as revealed by proteomics and phospho-proteomics

Jensen, P., Myhre, C. L., Lassen, P., Metaxas, A., Khan, A. M., Lambertsen, K. L., Babcock, A., Finsen, B., Larsen, M. R. & Kempf, S., 2017, I : OncoTarget. 8, 36, s. 60223-60242

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Understanding Alzheimer's disease by global quantification of protein phosphorylation and sialylated N-linked glycosylation profiles: A chance for new biomarkers in neuroproteomics?

Lassen, P. S., Thygesen, C., Larsen, M. R. & Kempf, S. J., 2017, I : Journal of Proteomics. 161, May, s. 11-25

Publikation: Bidrag til tidsskriftReviewForskningpeer review

2016

An integrated proteomics approach shows synaptic plasticity changes in an APP/PS1 Alzheimer's mouse model

Kempf, S. J., Metaxas, A., Ibáñez-Vea, M., Darvesh, S., Finsen, B. & Larsen, M. R., 7. jun. 2016, I : Oncotarget. 7, 23, s. 33627-33648

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A novel mass spectrometric strategy "BEMAP" reveals Extensive O-linked protein glycosylation in Enterotoxigenic Escherichia coli

Boysen, A., Palmisano, G., Krogh, T. J., Duggin, I. G., Larsen, M. R. & Møller-Jensen, J., 26. aug. 2016, I : Scientific Reports. 6, 13 s., 32016.

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Chronic low-dose-rate ionising radiation affects the hippocampal phosphoproteome in the ApoE-/- Alzheimer's mouse model

Kempf, S. J., Janik, D., Barjaktarovic, Z., Braga-Tanaka III, I., Tanaka, S., Neff, F., Saran, A., Larsen, M. R. & Tapio, S., 2016, I : OncoTarget. 7, 44, s. 71817-71832

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