Jørgen Vestbo

19982019

Research output per year

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Publikationer

Association of Cardiovascular Disease With Respiratory Disease

Carter, P., Lagan, J., Fortune, C., Bhatt, D. L., Vestbo, J., Niven, R., Chaudhuri, N., Schelbert, E. B., Potluri, R. & Miller, C., 7. maj 2019, I : Journal of the American College of Cardiology. 73, 17, s. 2166-2177

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

A systematic evaluation of the diagnostic criteria for COPD and exacerbations used in randomised controlled trials on the management of COPD exacerbations

Mathioudakis, A., Janner, J., Moberg, M., Alonso-Coello, P. & Vestbo, J., okt. 2019, I : ERJ Open Research. 5, 4, 3 s., 00136-2019.

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Benefit and safety of fluticasone furoate/vilanterol in the Salford Lung Study in chronic obstructive pulmonary disease (SLS COPD) according to baseline patient characteristics and treatment subgroups

Bakerly, N. D., Woodcock, A., Collier, S., Leather, D. A., New, J. P., Crawford, J., Harvey, C., Vestbo, J. & Boucot, I., 1. feb. 2019, I : Respiratory Medicine. 147, s. 58-65

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COPD exacerbations: The impact of long versus short courses of oral corticosteroids on mortality and pneumonia: Nationwide data on 67 000 patients with COPD followed for 12 months

Sivapalan, P., Ingebrigtsen, T. S., Rasmussen, D. B., Sørensen, R., Rasmussen, C. M., Jensen, C. B., Allin, K. H., Eklöf, J., Seersholm, N., Vestbo, J. & Jensen, J-U. S., mar. 2019, I : BMJ Open Respiratory Research. 6, 1, 8 s., e000407.

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End-product of fibrinogen is elevated in emphysematous chronic obstructive pulmonary disease and is predictive of mortality in the ECLIPSE cohort

Manon-Jensen, T., Langholm, L. L., Rønnow, S. R., Karsdal, M. A., Tal-Singer, R., Vestbo, J., Leeming, D. J., Miller, B. E. & Bülow Sand, J. M., 1. nov. 2019, I : Respiratory Medicine. 160, 9 s., 105814.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Epithelial IL-6 trans-signaling defines a new asthma phenotype with increased airway inflammation

Unbiased Biomarkers in Prediction of Respiratory Disease Outcomes study group, feb. 2019, I : Journal of Allergy and Clinical Immunology. 143, 2, s. 577–590

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Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations

Consortium, I. COPD. G., Sakornsakolpat, P., Prokopenko, D., Lamontagne, M., Reeve, N. F., Guyatt, A. L., Jackson, V. E., Shrine, N., Qiao, D., Bartz, T. M., Kim, D. K., Lee, M. K., Latourelle, J. C., Li, X., Morrow, J. D., Obeidat, M., Wyss, A. B., Bakke, P., Barr, R. G., Beaty, T. H. & 31 flere, Belinsky, S. A., Brusselle, G. G., Crapo, J. D., De Jong, K., Demeo, D. L., Fingerlin, T. E., Gharib, S. A., Gulsvik, A., Hall, I. P., Hokanson, J. E., Kim, W. J., Lomas, D. A., London, S. J., Meyers, D. A., O’connor, G. T., Rennard, S. I., Schwartz, D. A., Sliwinski, P., Sparrow, D., Strachan, D. P., Tal-singer, R., Tesfaigzi, Y., Vestbo, J., Vonk, J. M., Yim, J., Zhou, X., Bossé, Y., Manichaikul, A., Lahousse, L., Silverman, E. K. & Boezen, H. M., 1. mar. 2019, I : Nature Genetics. 51, 3, s. 494-505

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Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Lung Disease: the GOLD science committee report 2019

Singh, D., Agusti, A., Anzueto, A., Barnes, P. J., Bourbeau, J., Celli, B. R., Criner, G. J., Frith, P., Halpin, D. M. G., Han, M., López Varela, M. V., Martinez, F., Montes de Oca, M., Papi, A., Pavord, I. D., Roche, N., Sin, D. D., Stockley, R., Vestbo, J., Wedzicha, J. A. & 1 flere, Vogelmeier, C., 1. maj 2019, I : The European Respiratory Journal. 53, 5, 12 s., 1900164.

Publikation: Bidrag til tidsskriftReviewForskningpeer review

Lungesygdomme

Backer, V., Mortensen, J., Hostrup, M., Hansen, H., Godtfredsen, N. S., Shaker, S., Ulrik, C. S., Seersholm, N., Titlestad, I. L., Hilberg, O., Konge, L., Clementsen, P. F., Mellemgaard, A., Rasmussen, T. R., Tønnesen, P., Hansen, E. F., Bülow, H-H., Perch, M., Lund, T. K., Vestbo, J. & 9 flere, Lange, P., Fausbøll Mosbech, H., Bendstrup, E., Jennum, P., Armbruster, K., Ringbæk, T., Bødtger, U., Ravn, J. & Sørensen, J. B., 2019, Medicinsk Kompendium. de Muckadell, O. B. S., Hastrup Svendsen, J. & Vilstrup, H. (red.). 19. udg. Munksgaard , Bind 1. s. 783-937

Publikation: Bidrag til bog/antologi/rapport/konference-proceedingBidrag til bog/antologiUndervisning

Outcomes reported on the management of COPD exacerbations: a systematic survey of randomised controlled trials

Mathioudakis, A., Moberg, M., Janner, J., Alonso-Coello, P. & Vestbo, J., 1. apr. 2019, I : ERJ Open Research. 5, 2, 00072-2019.

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Plasma microfibrillar-associated protein 4 is not prognostic of emphysema progression but is associated with cardiovascular disease history and mortality in COPD patients

Johansson, S. L., Wulf-Johansson, H., Schlosser, A., Titlestad, I. L., Miller, B., Tal-Singer, R., Holmskov, U., Vestbo, J. & Sørensen, G. L., 1. apr. 2019, I : ERJ Open Research. 5, 2, 4 s., 00021-2019.

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Prognosis of COPD depends on severity of exacerbation history: A population-based analysis

Çolak, Y., Afzal, S., Marott, J. L., Nordestgaard, B. G., Vestbo, J., Ingebrigtsen, T. S. & Lange, P., aug. 2019, I : Respiratory Medicine. 155, s. 141-147 7 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Specific elastin degradation products are associated with poor outcome in the ECLIPSE COPD cohort

Rønnow, S. R., Langholm, L. L., Sand, J. M. B., Thorlacius-Ussing, J., Leeming, D. J., Manon-Jensen, T., Tal-Singer, R., Miller, B. E., Karsdal, M. A. & Vestbo, J., 1. mar. 2019, I : Scientific Reports. 9, 1, 4064.

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Type IV collagen turnover is predictive of mortality in COPD: A comparison to fibrinogen in a prospective analysis of the ECLIPSE cohort

Rønnow, S. R., Sand, J. M. B., Langholm, L. L., Manon-Jensen, T., Karsdal, M. A., Tal-Singer, R., Miller, B. E., Vestbo, J. & Leeming, DI. J., 1. apr. 2019, I : Respiratory Research. 20, 1, 63.

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Was the implementation strategy of the ProACT trial adequately proactive?

Mathioudakis, A. & Vestbo, J., mar. 2019, I : Breathe. 15, 1, s. 77-80

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β2-Adrenergic genotypes and risk of severe exacerbations in COPD: a prospective cohort study

Ingebrigtsen, T. S., Vestbo, J., Rode, L., Marott, J. L., Lange, P. & Nordestgaard, B. G., 2019, I : Thorax. 74, s. 934-940 7 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

2018

A computational framework for complex disease stratification from multiple large-scale datasets

Vestbo, J., U-BIOPRED Study Group & eTRIKS Consortium, 29. maj 2018, I : BMC Systems Biology. 12, 1, 23 s., 60.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

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At the root: Defining and halting progression of early chronic obstructive pulmonary disease

Martinez, F. J., Han, M. K., Allinson, J. P., Graham Barr, R., Boucher, R. C., Calverley, P. M. A., Celli, B. R., Christenson, S. A., Crystal, R. G., Fageras, M., Freeman, C. M., Groenke, L., Hoffman, E. A., Kesimer, M., Kostikas, K., Paine, R., Rafii, S., Rennard, S. I., Segal, L. N., Shaykhiev, R. & 6 flere, Stevenson, C., Tal-Singer, R., Vestbo, J., Woodruff, G. P., Curtis, J. L. & Wedzicha, J. A., 15. jun. 2018, I : American Journal of Respiratory and Critical Care Medicine. 197, 12, s. 1540-1551

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Automated oxygen control with O2matic® during admission with exacerbation of COPD

Hansen, E. F., Hove, J. D., Sandau Bech, C., Stæhr Jensen, J., Kallemose, T. & Vestbo, J., 28. dec. 2018, I : International Journal of Chronic Obstructive Pulmonary Disease. 13, 13, s. 3997-4003

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Biomarkers to guide antibiotic therapy for COPD exacerbations

Mathioudakis, A., Janjua, S., Normansell, R. & Vestbo, J., 18. okt. 2018, I : Cochrane Database of Systematic Reviews. 2018, 10, 13 s., CD013148.

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Blood eosinophil count thresholds and exacerbations in patients with chronic obstructive pulmonary disease

ECLIPSE Investigators & COPDGene Investigators, jun. 2018, I : Journal of Allergy and Clinical Immunology. 141, 6, s. 2037-2047.e10 11 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Cardiac Troponin I and Cardiovascular Risk in Patients With Chronic Obstructive Pulmonary Disease

Adamson, P. D., Anderson, J. A., Brook, R. D., Calverley, P. M. A., Celli, B. R., Cowans, N. J., Crim, C., Dixon, I. J., Martinez, F. J., Newby, D. E., Vestbo, J., Yates, J. C. & Mills, N. L., 4. sep. 2018, I : Journal of the American College of Cardiology. 72, 10, s. 1126-1137 12 s.

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Cigarette smoking and response to inhaled corticosteroids in COPD

Bhatt, S. P., Anderson, J. A., Brook, R. D., Calverley, P. M. A., Celli, B. R., Cowans, N. J., Crim, C., Martinez, F. J., Newby, D. E., Vestbo, J., Yates, J. C. & Dransfield, M. T., 1. jan. 2018, I : European Respiratory Journal. Supplement. 51, 1, 3 s., 1701393.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Computed tomography quantification of emphysema in people living with HIV and uninfected controls

COCOMO Study Group, 1. jul. 2018, I : European Respiratory Journal. 52, 1, 9 s., 1800296.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Diagnostic performance of clinical characteristics to detect airflow limitation in people living with HIV and in uninfected controls

the Copenhagen Co‐morbidity in HIV Infection (COCOMO) Study Group, 1. nov. 2018, I : HIV Medicine. 19, 10, s. 751-755

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Effectiveness versus efficacy trials in COPD: How study design influences outcomes and applicability

Woodcock, A., Boucot, I., Leather, D., Crawford, J., Collier, S., Diar Bakerly, N., Hilton, E. & Vestbo, J., 1. feb. 2018, I : European Respiratory Journal. Supplement. 51, 2, 11 s., 1701531.

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Emphysema and extrapulmonary tissue loss in COPD: a multi-organ loss of tissue phenotype

ECLIPSE Study Investigators, 1. feb. 2018, I : The European Respiratory Journal. 51, 2, 10 s., 1702146.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Exacerbation heterogeneity in COPD: subgroup analyses from the FLAME study

Vogelmeier, C. F., Chapman, K. R., Miravitlles, M., Roche, N., Vestbo, J., Thach, C., Banerji, D., Fogel, R., Patalano, F., Olsson, P., Kostikas, K. & Wedzicha, J. A., 26. apr. 2018, I : International Journal of Chronic Obstructive Pulmonary Disease. 13, s. 1125-1134 10 s.

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Exacerbations of Chronic Obstructive Pulmonary Disease and Cardiac Events: A Post Hoc Cohort Analysis from the SUMMIT Randomized Clinical Trial

SUMMIT Investigators, 1. jul. 2018, I : American Journal of Respiratory and Critical Care Medicine. 198, 1, s. 51-57 7 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Exhaled breath condensate in chronic obstructive pulmonary disease: Methodological challenges and clinical application

Lázár, Z., Horváth, I., Vestbo, J. & Bikov, A., 1. jun. 2018, I : Minerva Pneumologica. 57, 2, s. 42-56

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Extrafine inhaled triple therapy versus dual bronchodilator therapy in chronic obstructive pulmonary disease (TRIBUTE): a double-blind, parallel group, randomised controlled trial

Papi, A., Vestbo, J., Fabbri, L., Corradi, M., Prunier, H., Cohuet, G., Guasconi, A., Montagna, I., Vezzoli, S., Petruzzelli, S., Scuri, M., Roche, N. & Singh, D., 17. mar. 2018, I : The Lancet. 391, 10125, s. 1076-1084 9 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Fluticasone Furoate, Vilanterol, and Lung Function Decline in Patients with Moderate Chronic Obstructive Pulmonary Disease and Heightened Cardiovascular Risk

SUMMIT Investigators, 1. jan. 2018, I : American Journal of Respiratory and Critical Care Medicine. 197, 1, s. 47-55 9 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Impact of a long-acting beta-agonist and an inhaled corticosteroid in COPD patients with moderate airflow obstruction and CV disease or risk: a factorial analysis of the SUMMIT trial

investigators, T. SUMMIT., Calverley, P., Anderson, J. A., Brook, R., Crim, C., Kilbride, S., Martinez, F. J., Newby, D. E., Vestbo, J., Yates, J. & Celli, B., 7. feb. 2018, I : American Journal of Respiratory and Critical Care Medicine. 193, A6802.

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Inhaled corticosteroids in COPD: friend or foe?

Agusti, A., Fabbri, L. M., Singh, D., Vestbo, J., Celli, B., Franssen, F. M. E., Rabe, K. F. & Papi, A., 1. dec. 2018, I : European Respiratory Journal. Supplement. 52, 6, 14 s., 1801219.

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Left ventricular volume and wall stress are linked to lung function impairment in COPD

Alter, P., Jörres, R. A., Watz, H., Welte, T., Gläser, S., Schulz, H., Bals, R., Karch, A., Wouters, E. F. M., Vestbo, J., Young, D. & Vogelmeier, C. F., 15. jun. 2018, I : International Journal of Cardiology. 261, s. 172-178 7 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Patient-reported outcomes with initiation of fluticasone furoate/vilanterol versus continuing usual care in the Asthma Salford Lung Study

Svedsater, H., Jones, R., Bosanquet, N., Jacques, L., Lay-flurrie, J., Leather, D. A., Vestbo, J., Collier, S. & Woodcock, A., aug. 2018, I : Respiratory Medicine. 141, s. 198-206 9 s.

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Surfactant Protein D Deficiency Aggravates Cigarette Smoke-Induced Lung Inflammation by Upregulation of Ceramide Synthesis

Pilecki, B., Wulf-Johansson, H., Støttrup, C., Jørgensen, P. T., Djiadeu, P., Nexøe, A. B., Schlosser, A., Hansen, S. W. K., Madsen, J., Clark, H. W., Nielsen, C. H., Vestbo, J., Palaniyar, N., Holmskov, U. & Sorensen, G. L., 2018, I : Frontiers in Immunology. 9, 12 s., 3013.

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The emerging Chinese COPD epidemic

Vestbo, J. & Mathioudakis, A., 28. apr. 2018, I : The Lancet. 391, 10131, s. 1642-1643 2 s.

Publikation: Bidrag til tidsskriftKommentar/debatForskningpeer review

The Manchester Respiratory-related Sleep Symptoms scale for patients with COPD: development and validation

Khan, N., Vestbo, J., Garrow, A., Kolsum, U., Tyson, S., Singh, D. & Yorke, J., 21. dec. 2018, I : International Journal of Chronic Obstructive Pulmonary Disease. 13, s. 3885-3894

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Validation of lung density indices by cardiac CT for quantification of lung emphysema

Ronit, A., Kristensen, T., Çolak, Y., Kühl, J. T., Kalhauge, A., Lange, P., Nordestgaard, B., Vestbo, J., Nielsen, S. & Kofoed, K. F., 2018, I : International Journal of Chronic Obstructive Pulmonary Disease. 13, s. 3321-3330

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What is the impact of GOLD 2017 recommendations in primary care? – a descriptive study of patient classifications, treatment burden and costs

Gayle, A., Dickinson, S., Morris, K., Poole, C., Mathioudakis, A. G. & Vestbo, J., 2018, I : International Journal of Chronic Obstructive Pulmonary Disease. 13, s. 3485-3492

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Whole exome sequencing analysis in severe chronic obstructive pulmonary disease

Qiao, D., Ameli, A., Prokopenko, D., Chen, H., Kho, A. T., Parker, M. M., Morrow, J., Hobbs, B. D., Liu, Y., Beaty, T. H., Crapo, J. D., Barnes, K. C., Nickerson, D. A., Bamshad, M., Hersh, C. P., Lomas, D. A., Agusti, A., Make, B. J., Calverley, P. M. A., Donner, C. F. & 12 flere, Wouters, E. F., Vestbo, J., Paré, P. D., Levy, R. D., Rennard, S. I., Tal-Singer, R., Spitz, M. R., Sharma, A., Ruczinski, I., Lange, C., Silverman, E. K. & Cho, M. H., 1. nov. 2018, I : Human Molecular Genetics. 27, 21, s. 3801-3812

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Young and middle-aged adults with airflow limitation according to lower limit of normal but not fixed ratio have high morbidity and poor survival: a population-based prospective cohort study

Çolak, Y., Afzal, S., Nordestgaard, B. G., Vestbo, J. & Lange, P., 1. mar. 2018, I : European Respiratory Journal. Supplement. 51, 3, 9 s., 1702681.

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β-Blocker Therapy and Clinical Outcomes in Patients with Moderate Chronic Obstructive Pulmonary Disease and Heightened Cardiovascular Risk: An Observational Substudy of SUMMIT

SUMMIT Investigators, 1. maj 2018, I : American Thoracic Society. Annals (Print). 15, 5, s. 608-614 7 s.

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2017

A case-only genome-wide association study for assessing gene-sex interaction in Allergic rhinitis

Mohammadnejad, A., Brasch-Andersen, C., Haagerup, A., Vestbo, J., Baumbach, J. & Tan, Q., aug. 2017.

Publikation: Konferencebidrag uden forlag/tidsskriftPosterForskningpeer review

A multi-center randomized, controlled, open-label trial evaluating the effects of eosinophil-guided corticosteroid-sparing therapy in hospitalised patients with COPD exacerbations: The CORTICO steroid reduction in COPD (CORTICO-COP) study protocol

Sivapalan, P., Moberg, M., Eklöf, J., Janner, J., Vestbo, J., Laub, R. R., Browatzki, A., Armbruster, K., Wilcke, J. T., Seersholm, N., Weinreich, U. M., Titlestad, I. L., Andreassen, H. F., Ulrik, C. S., Bødtger, U., Nielsen, T. L., Hansen, E. F. & Jensen, J. U. S., 15. aug. 2017, I : B M C Pulmonary Medicine. 17, 7 s., 114.

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Association of Blood Eosinophil and Blood Neutrophil Counts with Asthma Exacerbations in the Copenhagen General Population Study

Vedel-Krogh, S., Nielsen, S. F., Lange, P., Vestbo, J. & Nordestgaard, B. G., 28. mar. 2017, I : Clinical Chemistry. 63, 4, s. 823-832 10 s.

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Biomarkers of collagen turnover are related to annual change in FEV1 in patients with chronic obstructive pulmonary disease within the ECLIPSE study

ECLIPSE Investigators, 4. dec. 2017, I : BMC Pulmonary Medicine. 17, 1, 10 s.

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