Forskningsområde

Genetisk epidemiologi, epigenetik, pigment genetik og aldersforskning.

CV

Uddannelse

• Ph.d. Københavns Universitet, 2008.
• Cand. Scient., Syddansk Universitet, 2002.

Akademisk karriere

• Post.doc. ved Forskningsenheden for Epidemiologi, Syddansk Universitet, 2009 -
• Retsgenetiker ved Retsmedicinsk Institut, Københavns Universitet, 2008 - 2009.
• Ph.d. studerende ved Retsmedicinsk Institut, Københavns Universitet, 2004 - 2008.
• Retsgenetiker ved Retsmedicinsk Institut, Københavns Universitet,  2003 - 2004.
• Forskningsassisent ved Retsmedicinsk Institut, Københavns Universitet, 2002 - 2003.

International erfaring

• Ph.d. ophold ved MRC Human Genetics Unit, Edinburgh 2006-2007.
• EU program - High Throughput Analysis of Single Nucleotide Polymorphisms (SNPs) for the forensic IDentification of Persons. http://www.snpforid.org 2003-2006.
• Erasmus udveksling ved Universitat de Barcelona 2000.

Publikationer
Mengel-From J, Børsting C, Sanchez JJ, Eiberg H, Morling N. Determination of cis/trans phase of variations in the MC1R gene with allele-specific PCR and single base extension. Electrophoresis. 2008 Dec; 29(23):4780-7.

Eiberg H, Troelsen J, Nielsen M, Mikkelsen A, Mengel-From J, Kjaer K, Hansen L. Blue eye color in humans may be caused by a perfectly associated founder mutation in a regulatory element located within the HERC2 gene inhibiting OCA2 expression. Human Genetics. 2008, 123(2):177-187.

Mengel-Jorgensen,J., Jensen,S.S., Rasmussen,A., Poehlsgaard,J., Iversen,J.J.L. & Kirpekar,F. Modifications in Thermus thermophilus 23 S ribosomal RNA are centered in regions of RNA-RNA contact. Journal of biological chemistry. (2006). 281: (31), 22108-22117.

Mengel-Jorgensen,J., Sanchez,J.J., Borsting,C., Kirpekar,F. & Morling,N. Typing of multiple SNPs using ribonuclease cleavage of DNA/RNA chimeric single base extension primers and detection by MALDI-TOF mass spectrometry. Analytical chemistry. (2005). 77: (16), 5229-5235.

Mengel-Jorgensen,J., Sanchez,J.J., Borsting,C., Kirpekar,F. & Morling,N. MALDI-TOF mass spectrometric detection of multiplex single base extended primers. A study of 17 y-chromosome single-nucleotide polymorphisms. Analytical chemistry. (2004). 76: (20), 6039-6045.

Madsen CT, 2004 Mengel-jørgensen J, Kirpekar F, Douthwaite S. Identifying the methyltransferases for m(5)U747 and m(5)U1939 in 23S rRNA using MALDI mass spectrometry. Nucleic Acids Res. 2003, 31, 4738-46.

Mengel-jørgensen J and Kirpekar F. Detection of pseudouridines and other modifications in tRNA cyanoethylation and MALDI mass spectrometry. Nucleic Acids Res. 2002, 30: e135.

Andre videnskabelige bidrag

Wächter A, Mengel-From J, Børsting C, Morling N. A 50 SNP-multiplex mass spectrometry assay for human identification. Forensic Science International: Genetic Supplement Series. 2008, 1:487-9.

Mengel-Jørgensen J, Wächter A, Børsting C, Sanchez JJ, Morling N PCR and SBE multiplexes for determination of SNPs associated with hair and eye colours in humans. DNA in forensic, Innsbruck, Austria, September 2006.

Mengel-Jørgensen J, Børsting C, Sanchez JJ, Morling N. Gene variations associated with hair and eye colours in humans 13th European Society for Pigment Cell Research, Barcelona, Spain. Pigment Cell research 2006, 19, 5, 520.

Mengel-From,J., Eiberg,H., Børsting,C. & Morling,N. Genetic screening of 15 SNPs in the MC1R gene in relation to hair colour in Danes. Elsevier (2006).55-57. Progress in Forensic Genetics 11.

Mengel-From,J., Sanchez Sanchez,J.J., Børsting,C., Kirpekar,F. & Morling,N. Multiplex Y chromosome SNP genotyping using MALDI-TOF mass spectrometry. Elsevier (2004).15-17. Progress in Forensic Genetics 10.

Sanchez,J.J., Børsting,C., Hernandez,A., Mengel-From,J. & Morling,N. Y chromosome SNP haplogroups in Danes, Greenlanders and Somalis. Elsevier (2004).347-349. Progress in Forensic Genetics 10.

Phillips C., Lareu M., Brion M., Sobrino B., Carracedo A., Boersting C., Kirpekar F., Mengel-Joergensen J., Sanchez J.J., Morling N., Syndercombe Court D., Balogh K., Bogus M., Bender K., SchneiderP.M. Selecting Single Nucleotide Polymorphisms for Forensic Applications Elsevier International Congress Series 1261 (2004) Progress in Forensic Genetics 10.