Jens Skorstengaard Andersen

Søgeresultater

• 2024

  Endogenous Tagging of Ciliary Genes in Human RPE1 Cells for Live-Cell Imaging

  Kuhns, S., Juhl, A. D., Anvarian, Z., Wüstner, D., Pedersen, L. B. & Andersen, J. S., 2024, Cilia: Methods and Protocols. Mennella, V. (red.). Humana Press, s. 147-166 (Methods in Molecular Biology, Bind 2725).

  Publikation: Kapitel i bog/rapport/konference-proceeding › Kapitel i bog › Forskning › peer review

  • Subcellular Localization 100%
  • Cellular Imaging 100%
  • Intraflagellar Transport 100%
  • CRISPR 100%
  • Cellular Distribution 100%

• Exploring the structural landscape of DNA maintenance proteins

  Schou, K. B., Mandacaru, S., Tahir, M., Tom, N., Nilsson, A. S., Andersen, J. S., Tiberti, M., Papaleo, E. & Bartek, J., dec. 2024, I: Nature Communications. 15, 17 s., 7748.

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  • Peptide Sequence 100%
  • Poly ADP Ribose Polymerase 100%
  • Protein Family 100%
  • Genome Instability 100%
  • Evolution 100%
  3 Downloads (Pure)

• Uncovering structural themes across cilia microtubule inner proteins with implications for human cilia function

  Andersen, J. S., Vijayakumaran, A., Godbehere, C., Lorentzen, E., Mennella, V. & Schou, K. B., dec. 2024, I: Nature Communications. 15, 1, 17 s., 2687.

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  • Cilium 100%
  • Centrosome 50%
  • Binding Protein 25%
  • Cell Division 25%
  • Shotgun Sequencing 25%
  10 Downloads (Pure)
• 2023

  ARS2 instructs early transcription termination-coupled RNA decay by recruiting ZC3H4 to nascent transcripts

  Rouvière, J. O., Salerno-Kochan, A., Lykke-Andersen, S., Garland, W., Dou, Y., Rathore, O., Molska, E. Š., Wu, G., Schmid, M., Bugai, A., Jakobsen, L., Žumer, K., Cramer, P., Andersen, J. S., Conti, E. & Jensen, T. H., 6. jul. 2023, I: Molecular Cell. 83, 13, s. 2240-2257

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  • RNA 100%
  • Transcription Termination 100%
  • RNA Polymerase II 66%
  • Polyadenylation 66%
  • Transcription 33%

• Dual agonistic and antagonistic roles of ZC3H18 provide for co-activation of distinct nuclear RNA decay pathways

  Polák, P., Garland, W., Rathore, O., Schmid, M., Salerno-Kochan, A., Jakobsen, L., Gockert, M., Gerlach, P., Silla, T., Andersen, J. S., Conti, E. & Jensen, T. H., 28. nov. 2023, I: Cell Reports. 42, 11, 21 s., 113325.

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  • RNA 100%
  • Ribonuclease 25%
  • Mammalian Cell 25%
  • Nuclear Protein 25%
  • Nucleoplasm 25%
  29 Downloads (Pure)

• The IFT81-IFT74 complex acts as an unconventional RabL2 GTPase-activating protein during intraflagellar transport

  Boegholm, N., Petriman, N. A., Loureiro-López, M., Wang, J., Vela, M. I. S., Liu, B., Kanie, T., Ng, R., Jackson, P. K., Andersen, J. S. & Lorentzen, E., 18. sep. 2023, I: EMBO Journal. 42, 18, 25 s., e111807.

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  • Intraflagellar Transport 100%
  • GTPase-activating Protein 100%
  • Enzymatic Hydrolysis 37%
  • Guanosine Triphosphate 37%
  • Cilium 25%
  40 Downloads (Pure)

• Transient accumulation and bidirectional movement of KIF13B in primary cilia

  Juhl, A. D., Anvarian, Z., Kuhns, S., Berges, J., Andersen, J. S., Wüstner, D. & Pedersen, L. B., 1. mar. 2023, I: Journal of Cell Science. 136, 5

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  • Primary Cilium 100%
  • Kinesin 2 100%
  • Kinesin 100%
  • Cilium 100%
  • Intraflagellar Transport 75%
  50 Downloads (Pure)
• 2022

  Biochemically validated structural model of the 15-subunit intraflagellar transport complex IFT-B

  Petriman, N. A., Loureiro-López, M., Taschner, M., Zacharia, N. K., Georgieva, M. M., Boegholm, N., Wang, J., Mourão, A., Russell, R. B., Andersen, J. S. & Lorentzen, E., 15. dec. 2022, I: EMBO Journal. 41, 24, e112440.

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  • Cilium 100%
  • Mass Spectroscopy 100%
  • Locomotion 100%
  • X Ray Scattering 100%
  • Mutagenesis 100%
  45 Downloads (Pure)

• Rapid factor depletion highlights intricacies of nucleoplasmic RNA degradation

  Gockert, M., Schmid, M., Jakobsen, L., Jens, M., Andersen, J. S. & Jensen, T. H., 22. feb. 2022, I: Nucleic Acids Research. 50, 3, s. 1583-1600

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  • RNA 100%
  • RNA Degradation 100%
  • Intron 60%
  • Proteome 20%
  • Specificity Factor 20%
  120 Downloads (Pure)
• 2021

  CEP78 functions downstream of CEP350 to control biogenesis of primary cilia by negatively regulating CP110 levels

  Gonçalves, A. B., Hasselbalch, S. K., Joensen, B. B., Patzke, S., Martens, P., Ohlsen, S. K., Quinodoz, M., Nikopoulos, K., Suleiman, R., Jeppesen, M. P. D., Weiss, C., Christensen, S. T., Rivolta, C., Andersen, J. S., Farinelli, P. & Pedersen, L. B., aug. 2021, I: eLife. 10, 34 s., e63731.

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  • Biogenesis 100%
  • Cilium 100%
  • Ciliogenesis 100%
  • Ubiquitination 50%
  • Ubiquitin 50%
  105 Downloads (Pure)

• MCM3 upregulation confers endocrine resistance in breast cancer and is a predictive marker of diminished tamoxifen benefit

  Løkkegaard, S., Elias, D., Alves, C. L., Bennetzen, M. V., Lænkholm, A. V., Bak, M., Gjerstorff, M. F., Johansen, L. E., Vever, H., Bjerre, C., Kirkegaard, T., Nordenskjöld, B., Fornander, T., Stål, O., Lindström, L. S., Esserman, L. J., Lykkesfeldt, A. E., Andersen, J. S., Leth-Larsen, R. & Ditzel, H. J., jan. 2021, I: npj Breast Cancer. 7, 15 s., 2.

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  • Breast Cancer 100%
  • Upregulation 100%
  • Tamoxifen 100%
  • Predictive Marker 100%
  • Minichromosome Maintenance Protein 3 100%
  48 Downloads (Pure)

• The long non-coding RNA MIR31HG regulates the senescence associated secretory phenotype

  Montes, M., Lubas, M., Arendrup, F. S., Mentz, B., Rohatgi, N., Tumas, S., Harder, L. M., Skanderup, A. J., Andersen, J. S. & Lund, A. H., dec. 2021, I: Nature Communications. 12, 1, 17 s., 2459.

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  • Long Non-Coding RNA 100%
  • Secretion (Process) 66%
  • Transcription 33%
  • P16 33%
  • Phosphotransferase 33%
  50 Downloads (Pure)
• 2020

  A systems approach delivers a functional microRNA catalog and expanded targets for seizure suppression in temporal lobe epilepsy

  Venø, M. T., Reschke, C. R., Morris, G., Connolly, N. M. C., Su, J., Yan, Y., Engel, T., Jimenez-Mateos, E. M., Harder, L. M., Pultz, D., Haunsberger, S. J., Pal, A., Heller, J. P., Campbell, A., Langa, E., Brennan, G. P., Conboy, K., Richardson, A., Norwood, B. A. & Costard, L. S. & 15 flere, Neubert, V., Del Gallo, F., Salvetti, B., Vangoor, V. R., Sanz-Rodriguez, A., Muilu, J., Fabene, P. F., Pasterkamp, R. J., Prehn, J. H. M., Schorge, S., Andersen, J. S., Rosenow, F., Bauer, S., Kjems, J. & Henshall, D. C., 7. jul. 2020, I: PNAS. 117, 27, s. 15977-15988 27.

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  • Hippocampus 100%
  • Argonaute Protein 100%
  • Temporal Cortex 100%
  • Epileptic Seizure 100%
  • microRNA 100%

• CD10: A novel marker of bone marrow adipocyte progenitors

  Jafari, A., Alshammary, A., Isa, A., Harkness, L., Rauch, A., Tencerova, M., Nielsen, M., Andersen, J., Andersen, T. L., Aldahmash, A. & Kassem, M., 1. nov. 2020, I: Journal of Bone and Mineral Research. 35, Suppl. 1, s. 33 1 s., 1086.

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• Human RTEL1 associates with Poldip3 to facilitate responses to replication stress and R-loop resolution

  Björkman, A., Johansen, S. L., Lin, L., Schertzer, M., Kanellis, D. C., Katsori, A.-M., Christensen, S. T., Luo, Y., Andersen, J. S., Elsässer, S. J., Londono-Vallejo, A., Bartek, J. & Schou, K. B., 2020, I: Genes & Development. 34, 15-16, s. 1065-1074

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  • DNA Synthesis 100%
  • R-Loop 100%
  • Genome Instability 66%
  • DNA Repair 33%
  • Transcription 33%
  63 Downloads (Pure)

• Spatial Characterization of the Human Centrosome Proteome Opens up New Horizons for a Small but Versatile Organelle

  Danielsson, F., Mahdessian, D., Axelsson, U., Sullivan, D., Uhlén, M., Andersen, J. S., Thul, P. J. & Lundberg, E., dec. 2020, I: Proteomics. 20, 23, 7 s., 1900361.

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  • Proteome 100%
  • Centrosome 100%
  • Signal Transduction 16%
  • Ubiquitination 16%
  • Immunofluorescence 16%
  61 Downloads (Pure)

• The human ZC3H3 and RBM26/27 proteins are critical for PAXT-mediated nuclear RNA decay

  Silla, T., Schmid, M., Dou, Y., Garland, W., Milek, M., Imami, K., Johnsen, D., Polak, P., Andersen, J. S., Selbach, M., Landthaler, M. & Jensen, T. H., 18. mar. 2020, I: Nucleic Acids Research. 48, 5, s. 2518-2530 13 s.

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  • RNA 100%
  • Proteome 20%
  • Cofactor 20%
  • PABPN1 20%
  151 Downloads (Pure)
• 2019

  Rab35 controls cilium length, function and membrane composition

  Kuhns, S., Seixas, C., Pestana, S., Tavares, B., Nogueira, R., Jacinto, R., Ramalho, J. S., Simpson, J. C., Andersen, J. S., Echard, A., Lopes, S. S., Barral, D. C. & Blacque, O. E., 4. okt. 2019, I: EMBO Reports. 20, 10, 23 s., e47625.

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  • Cilium 100%
  • Sonic Hedgehog 50%
  • Mammalian Cell 33%
  • Zebra Fish 33%
  • Hedgehog Signaling Pathway 33%
  127 Downloads (Pure)

• Selective autophagy maintains centrosome integrity and accurate mitosis by turnover of centriolar satellites

  Holdgaard, S. G., Cianfanelli, V., Pupo, E., Lambrughi, M., Lubas, M., Nielsen, J. C., Eibes, S., Maiani, E., Harder, L. M., Wesch, N., Foged, M. M., Maeda, K., Nazio, F., de la Ballina, L. R., Dötsch, V., Brech, A., Frankel, L. B., Jäättelä, M., Locatelli, F. & Barisic, M. & 8 flere, Andersen, J. S., Bekker-Jensen, S., Lund, A. H., Rogov, V. V., Papaleo, E., Lanzetti, L., De Zio, D. & Cecconi, F., 2019, I: Nature Communications. 10, s. 4176 19 s., 4176.

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  • Centrosome 100%
  • Selective Autophagy 100%
  • Autophagy 40%
  • Chromosome Segregation 20%
  • C-Terminus 10%
  93 Downloads (Pure)
• 2018

  CEP128 Localizes to the Subdistal Appendages of the Mother Centriole and Regulates TGF-β/BMP Signaling at the Primary Cilium

  Mönnich, M., Borgeskov, L., Breslin, L., Jakobsen, L., Rogowski, M., Doganli, C., Schrøder, J. M., Mogensen, J. B., Blinkenkjær, L., Harder, L. M., Lundberg, E., Geimer, S., Christensen, S. T., Andersen, J. S., Larsen, L. A. & Pedersen, L. B., 6. mar. 2018, I: Cell Reports. 22, 10, s. 2584-2592

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  • Signaling Protein 100%
  • Bone Morphogenetic Protein 100%
  • Cilium 100%
  • Centriole 100%
  • Cancer Growth Factor 100%
  217 Downloads (Pure)

• Characterizing ZC3H18, a Multi-domain Protein at the Interface of RNA Production and Destruction Decisions

  Winczura, K., Schmid, M., Iasillo, C., Molloy, K. R., Harder, L. M., Andersen, J. S., LaCava, J. & Jensen, T. H., 2. jan. 2018, I: Cell Reports. 22, 1, s. 44-58

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  • RNA 100%
  • Protein Tertiary Structure 100%
  • RNA Metabolism 50%
  • Cap Binding Complex 50%
  • Histone 50%
  198 Downloads (Pure)

• DNA damage-induced dynamic changes in abundance and cytosol-nuclear translocation of proteins involved in translational processes, metabolism, and autophagy

  Bennetzen, M. V., Kosar, M., Bunkenborg, J., Payne, M. R., Bartkova, J., Lindström, M. S., Lukas, J., Andersen, J. S., Bartek, J. & Larsen, D. H., sep. 2018, I: Cell Cycle. 17, 17, s. 2146-2163

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  • Metabolic Pathway 100%
  • Proteomics 100%
  • Ribosomal Protein 100%
  • DNA Damage 100%
  • Autophagy 100%

• eIF5A is required for autophagy by mediating ATG3 translation

  Lubas, M., Harder, L. M., Kumsta, C., Tiessen, I., Hansen, M., Andersen, J. S., Lund, A. H. & Frankel, L. B., 2018, I: EMBO Reports. 19, 6, 17 s., e46072.

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  • Initiation Factor 100%
  • Autophagy 100%
  • Autophagosome 33%
  • Protein Interaction 16%
  • Transcription 16%

• IFT20 modulates ciliary PDGFRα signaling by regulating the stability of Cbl E3 ubiquitin ligases

  Schmid, F. M., Schou, K. B., Vilhelm, M. J., Holm, M. S., Breslin, L., Farinelli, P., Larsen, L. A., Andersen, J. S., Pedersen, L. B. & Christensen, S. T., 2. jan. 2018, I: The Journal of Cell Biology. 217, 1, s. 151-161

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  • Ubiquitin-Conjugating Enzyme 100%
  • Transport Protein 100%
  • Mitochondrial Membrane Transport Protein 100%
  • Carrier Protein 100%
  • Cilium 42%
  132 Downloads (Pure)
• 2017

  Degradation of protein translation machinery by amino acid starvation-induced macroautophagy

  Gretzmeier, C., Eiselein, S., Johnson, G. R., Engelke, R., Nowag, H., Zarei, M., Küttner, V., Becker, A. C., Rigbolt, K. T. G., Høyer-Hansen, M., Andersen, J. S., Münz, C., Murphy, R. F. & Dengjel, J., 2017, I: Autophagy. 13, 6, s. 1064-1075

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  • Amino Acids 100%
  • Macroautophagy 100%
  • Translation (Protein Synthesis) 100%
  • Protein Degradation 40%
  • Volume 40%

• Mutually Exclusive CBC-Containing Complexes Contribute to RNA Fate

  Giacometti, S., Benbahouche, N. E. H., Domanski, M., Robert, M. C., Meola, N., Lubas, M., Bukenborg, J., Andersen, J. S., Schulze, W. M., Verheggen, C., Kudla, G., Jensen, T. H. & Bertrand, E., 2017, I: Cell Reports. 18, 11, s. 2635-2650

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  • RNA 100%
  • Cap Binding Complex 100%
  • Steady State 12%
  • Biogenesis 12%
  • Binding Competition 12%
  217 Downloads (Pure)
• 2016

  Identification of a Nuclear Exosome Decay Pathway for Processed Transcripts

  Meola, N., Domanski, M., Karadoulama, E., Chen, Y., Gentil, C., Pultz, D., Vitting-Seerup, K., Lykke-Andersen, S., Andersen, J. S., Sandelin, A. G. & Jensen, T. H., 3. nov. 2016, I: Molecular Cell. 64, 3, s. 520-533

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• SDCCAG8 interacts with rab effector proteins rabep2 and erc1 and is required for hedgehog signaling

  Airik, R., Schueler, M., Airik, M., Cho, J., Ulanowicz, K. A., Porath, J. D., Hurd, T. W., Bekker-Jensen, S., Schrøder, J. M., Andersen, J. S. & Hildebrandt, F., 25. maj 2016, I: PLOS ONE. 11, 5, 19 s., e0156081.

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  • Centrosome 100%
  • Hedgehog Signaling Pathway 100%
  • Ciliogenesis 66%
  • Small Interfering RNA 33%
  • Proteomics 33%
  284 Downloads (Pure)
• 2015

  Regulated assembly of a supramolecular centrosome scaffold in vitro

  Woodruff, J. B., Wueseke, O., Viscardi, V., Mahamid, J., Ochoa, S. D., Bunkenborg, J., Widlund, P. O., Pozniakovsky, A., Zanin, E., Bahmanyar, S., Zinke, A., Hong, S. H., Decker, M., Baumeister, W., Andersen, J. S., Oegema, K. & Hyman, A. A., 2015, I: Science. 348, 6236, s. 808-812

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  • Centrosome 100%
  • Pericentriolar Material 100%
  • Coiled Coil 33%
  • Porosity 33%
  • Caenorhabditis Elegans 16%

• Treatment of non-IBD anal fistula

  Lundby, L., Hagen, K., Christensen, P., Buntzen, S., Thorlacius-Ussing, O., Andersen, J., Krupa, M. & Qvist, N., maj 2015, I: Danish Medical Journal. 62, 5, C5088.

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  • Fistula 100%
  • Inflammatory Bowel Disease 100%
  • Anal Fistula 100%
  • Magnetic Resonance Imaging 12%
  • Recurrent Disease 12%
• 2014

  A divergent calponin homology (NN-CH) domain defines a novel family: Implications for evolution of ciliary IFT complex B proteins

  Schou, K. B., Andersen, J. S. & Pedersen, L. B., 2014, I: Bioinformatics. 30, 7, s. 899-902

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  • Calponin Homology Domain 100%
  • Intraflagellar Transport 100%
  • Calponin 100%
  • Microtubule-Associated Protein 50%
  • N-Terminus 25%

• ANCHR mediates Aurora-B-dependent abscission checkpoint control through retention of VPS4

  Thoresen, S. B., Campsteijn, C., Vietri, M., Schink, K. O., Liestøl, K., Andersen, J. S., Raiborg, C. & Stenmark, H., jun. 2014, I: Nature Cell Biology. 16, 6, s. 547-557

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  • Abscission 100%
  • Cell Division 10%
  • ATPase 10%
  • DNA Damage 10%
  • Aneuploidy 10%

• Characterization of early autophagy signaling by quantitative phosphoproteomics

  Rigbolt, K. T., Zarei, M., Sprenger, A., Becker, A. C., Diedrich, B., Huang, X., Eiselein, S., Kristensen, A. R., Gretzmeier, C., Andersen, J. S., Zi, Z. & Dengjel, J., 2014, I: Autophagy. 10 , 2, s. 356 - 371

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  • Phosphoproteomics 100%
  • Autophagy 100%
  • Dynamics 14%
  • Signal Transduction 14%
  • Anabolism 14%

• Inducing autophagy: A comparative phosphoproteomic study of the cellular response to ammonia and rapamycin

  Harder, L. M., Bunkenborg, J. & Andersen, J. S., 2014, I: Autophagy. 10, 2, s. 339 - 355

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  • Phosphoproteomics 100%
  • Autophagy 100%
  • Unfolded Protein Response 25%
  • MAPK3 25%
  • Phosphoprotein 12%

• Quantitative proteomics identifies unanticipated regulators of nitrogen- and glucose starvation

  Rødkær, S. V., Pultz, D., Brusch, M., Bennetzen, M. V., Falkenby, L. G., Andersen, J. S. & Færgeman, N. J., aug. 2014, I: Molecular BioSystems. 10, 8, s. 2176-2188

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  • Quantitative Proteomics 100%
  • Hsp90 66%
  • Isoform 33%
  • Mass Spectrometry 33%
  • Saccharomyces cerevisiae 33%

• Regulation of autophagy by cytosolic acetyl-coenzyme A

  Mariño, G., Pietrocola, F., Eisenberg, T., Kong, Y., Malik, S. A., Andryushkova, A., Schroeder, S., Pendl, T., Harger, A., Niso-Santano, M., Zamzami, N., Scoazec, M., Durand, S., Enot, D. P., Fernández, Á. F., Martins, I., Kepp, O., Senovilla, L., Bauvy, C. & Morselli, E. & 12 flere, Vacchelli, E., Bennetzen, M., Magnes, C., Sinner, F., Pieber, T., López-Otín, C., Maiuri, M. C., Codogno, P., Andersen, J. S., Hill, J. A., Madeo, F. & Kroemer, G., 6. mar. 2014, I: Molecular Cell. 53, 5, s. 710-725 16 s.

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  • Autophagy 100%
  • Coenzyme A 100%
  • Acetyl-CoA 100%
  • EP300 22%
  • Protein Catabolism 11%

• Renal-Retinal Ciliopathy Gene Sdccag8 Regulates DNA Damage Response Signaling

  Airik, R., Slaats, G. G., Guo, Z., Weiss, A.-C., Khan, N., Ghosh, A., Hurd, T. W., Bekker-Jensen, S., Schrøder, J. M., Elledge, S. J., Andersen, J. S., Kispert, A., Castelli, M., Boletta, A., Giles, R. H. & Hildebrandt, F., 10. apr. 2014, I: Journal of the American Society of Nephrology. 25, 11, s. 2573-2583

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  • Ciliopathy 100%
  • DNA Damage Response 100%
  • Retina Degeneration 100%
  • Disease 66%
  • Cell Cycle 33%

• The Caenorhabditis elegans pericentriolar material components SPD-2 and SPD-5 are monomeric in the cytoplasm before incorporation into the PCM matrix

  Wueseke, O., Bunkenborg, J., Hein, M. Y., Zinke, A., Viscardi, V., Woodruff, J. B., Oegema, K., Mann, M., Andersen, J. S. & Hyman, A. A., 1. okt. 2014, I: Molecular Biology of the Cell. 25, 19, s. 2984-2992 9 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Caenorhabditis Elegans 100%
  • Pericentriolar Material 100%
  • Centrosome 37%
  • Mass Spectrometry 12%
  • Phosphotransferase 12%
• 2013

  Acetylation dynamics of human nuclear proteins during the ionizing radiation-induced DNA damage response

  Bennetzen, M. V., Larsen, D. H., Dinant, C., Watanabe, S., Bartek, J., Lukas, J. & Andersen, J. S., 2013, I: Cell Cycle. 12, 11, s. 1688-1695

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Dynamics 100%
  • Nuclear Protein 100%
  • DNA Damage Response 100%
  • Acetylation 100%
  • Ionizing Radiation 100%

• Centrosome isolation and analysis by mass spectrometry-based proteomics

  Jakobsen, L., Schrøder, J. M., Larsen, K. M., Lundberg, E. & Andersen, J. S., 2013, Methods in Enzymology, Cilia, part B. Marshall, W. E. (red.). Elsevier, s. 371-393 23 s. (Methods in Enzymology, Bind 525).

  Publikation: Kapitel i bog/rapport/konference-proceeding › Kapitel i bog › Forskning › peer review

  • Mass Spectrometry 100%
  • Proteomics 100%
  • Centrosome 100%
  • Centriole 100%
  • Cilium 50%

• Protein tyrosine phosphatase SHP2/PTPN11 mistargeting as a consequence of SH2-domain point mutations associated with Noonan Syndrome and leukemia

  Müller, P. J., Rigbolt, K. T. G., Paterok, D., Piehler, J., Vanselow, J., Lasonder, E., Andersen, J. S., Schaper, F. & Sobota, R. M., 2013, I: Journal of Proteomics. 84, 12, s. 132-147

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Point Mutation 100%
  • SH2 Domain 100%
  • Protein Tyrosine Phosphatase 100%
  • Mass Spectrometry 28%
  • Enzyme Activity 28%

• The human cap-binding complex is functionally connected to the nuclear RNA exosome

  Andersen, P. R., Domanski, M., Kristiansen, M. S., Storvall, H., Ntini, E., Verheggen, C., Schein, A., Bunkenborg, J., Poser, I., Hallais, M., Sandberg, R., Hyman, A., Lacava, J., Rout, M. P., Andersen, J. S., Bertrand, E. & Jensen, T. H., 2013, I: Nature Structural and Molecular Biology. 20, 12, s. 1367-1376

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • RNA 100%
  • Cap Binding Complex 100%
  • Ribonucleoprotein 33%
  • Quality Control 16%
  • Immunoprecipitation 16%
• 2012

  Advancing cell biology through proteomics in space and time (PROSPECTS)

  Lamond, A. I., Uhlen, M., Horning, S., Makarov, A., Robinson, S. C., Serrano, L., Hartl, F. U., Baumeister, W., Werenskiold, A. K., Andersen, J. S., Vorm, O., Linial, M., Aebersold, R. & Mann, M., 2012, I: Molecular and Cellular Proteomics. 11, 3, s. O112.017731

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Proteomics 100%
  • Proteome 22%
  • Dynamics 11%
  • Posttranslational Modification 11%
  • Protein Characterization 11%

• Exome capture reveals ZNF423 and CEP164 mutations, linking renal ciliopathies to DNA damage response signaling

  Chaki, M., Airik, R., Ghosh, A. K., Giles, R. H., Chen, R., Slaats, G. G., Wang, H., Hurd, T. W., Zhou, W., Cluckey, A., Gee, H. Y., Ramaswami, G., Hong, C.-J., Hamilton, B. A., Cervenka, I., Ganji, R. S., Bryja, V., Arts, H. H., van Reeuwijk, J. & Oud, M. M. & 53 flere, Letteboer, S. J. F., Roepman, R., Husson, H., Ibraghimov-Beskrovnaya, O., Yasunaga, T., Walz, G., Eley, L., Sayer, J. A., Schermer, B., Liebau, M. C., Benzing, T., Le Corre, S., Drummond, I., Janssen, S., Allen, S. J., Natarajan, S., O'Toole, J. F., Attanasio, M., Saunier, S., Antignac, C., Koenekoop, R. K., Ren, H., Lopez, I., Nayir, A., Stoetzel, C., Dollfus, H., Massoudi, R., Gleeson, J. G., Andreoli, S. P., Doherty, D. G., Lindstrad, A., Golzio, C., Katsanis, N., Pape, L., Abboud, E. B., Al-Rajhi, A. A., Lewis, R. A., Omran, H., Lee, E.Y.-H. P., Wang, S., Sekiguchi, J. M., Saunders, R., Johnson, C. A., Garner, E., Vanselow, K., Andersen, J. S., Shlomai, J., Nurnberg, G., Nurnberg, P., Levy, S., Smogorzewska, A., Otto, E. A. & Hildebrandt, F., 2012, I: Cell Stem Cell. 150, 3, s. 533-48 16 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • DNA Damage Response 100%
  • Exome 100%
  • DNA Damage 50%
  • Genetics 25%
  • Gene Product 25%

• Friend or food: Different cues to the autophagosomal proteome

  Becker, A. C., Bunkenborg, J., Eisenberg, T., Harder, L. M., Schroeder, S., Madeo, F., Andersen, J. S. & Dengjel, J., 2012, I: Autophagy. 8, 6, s. 995-996

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning

  • Proteome 100%
  • Autophagosome 100%
  • Mass Spectrometry 33%
  • Proteomics 33%
  • Proteasome 33%

• Global mapping of protein phosphorylation events identifies Ste20, Sch9 and the cell-cycle regulatory kinases Cdc28/Pho85 as mediators of fatty acid starvation responses in Saccharomyces cerevisiae

  Pultz, D., Bennetzen, M. V., Rødkær, S. V., Zimmermann, C., Enserink, J. M., Andersen, J. S. & Færgeman, N. J., 2012, I: Molecular BioSystems. 8, 3, s. 796-803

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Saccharomyces cerevisiae 100%
  • Cell Cycle 100%
  • Fatty Acid Synthesis 100%
  • Mediator 100%
  • Protein Phosphorylation 100%

• Identification of autophagosome-associated proteins and regulators by quantitative proteomic analysis and genetic screens

  Dengjel, J., Høyer-Hansen, M., Nielsen, M., Eisenberg, T., Harder, L. M., Schandorff, S., Farkas, T., Kirkegaard, T., Becker, A. C., Schroeder, S., Vanselow, K., Lundberg, E., Nielsen, M. M., Kristensen, A. R., Akimov, V., Bunkenborg, J., Madeo, F., Jäättelä, M. & Andersen, J. S., 2012, I: Molecular and Cellular Proteomics. 11, 3, s. M111.014035

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Quantitative Proteomics 100%
  • Genetic Screen 100%
  • Autophagosome 100%
  • Autophagy 42%
  • Genetics 14%

• Mass spectrometric identification of proteins that interact through specific domains of the poly(A) binding protein

  Richardson, R., Denis, C. L., Zhang, C., Nielsen, M. E. O., Chiang, Y.-C., Kierkegaard, M., Wang, X., Lee, D. J., Andersen, J. S. & Yao, G., 2012, I: Molecular Genetics and Genomics. 287, 9, s. 711-730

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Poly(A)-Binding Protein 100%
  • UPF1 100%
  • Mass Spectrometry 66%
  • Nonsense-Mediated Decay 66%
  • RRM1 66%

• Phosphoproteomic analysis of cells treated with longevity-related autophagy inducers

  Bennetzen, M. V., Mariño, G., Pultz, D., Morselli, E., Færgeman, N. J., Kroemer, G. & Andersen, J. S., 2012, I: Cell Cycle. 11, 9, s. 1827-1840 14 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Phosphoproteomics 100%
  • Autophagy 100%
  • Resveratrol 57%
  • Posttranslational Modification 28%
  • Mass Spectrometry 14%

• PhosphoSiteAnalyzer: A Bioinformatic Platform for Deciphering Phospho Proteomes Using Kinase Predictions Retrieved from NetworKIN

  Bennetzen, M. V., Cox, J., Mann, M. & Andersen, J. S., 2012, I: Journal of Proteome Research. 11, 6, s. 3480-3486

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Phosphotransferase 100%
  • Kinase 100%
  • Proteome 100%
  • Phosphoproteomics 75%
  • Phosphopeptide 25%