Henrik Jørn Ditzel

Søgeresultater

• 2023

  Patient-derived organoids to optimize CDK4/6 inhibitor-based treatment selection in early breast cancer

  Alves, C. M. L., Nissen, N., Policastro, B., Kristensen, N., Rosengren, F., Johansen, L. E., Staaf, J. & Ditzel, H. J., 9. okt. 2023.

  Publikation: Konferencebidrag uden forlag/tidsskrift › Poster › Forskning

  Åben adgang
• 2019

  Targeting CD79b with chimeric antigen receptors shows potent pre-clinical efficacy in mantle cell lymphoma

  Ormhøj, M., Scarfò, I., Andersen, R. S., Cédile, O., Bailey, S. R., Lorrey, S., Bouffard, A. A., Castano, A. P., Nyvold, C. G., Christensen, J. H., Gjerstorff, M., Ditzel, H., Weinstock, D. M., Barington, T. & Maus, M. V., 14. feb. 2019.

  Publikation: Konferencebidrag uden forlag/tidsskrift › Poster › Forskning › peer review
• 2018

  Proteomic comparison of clinical breast cancer samples, corresponding patient derived xenografts (PDX) and mammospheres reveal increased cholesterol biosynthesis as a key feature of cancer stem cells

  Ehmsen, S., Pedersen, M. H., Arslanagic, A., Terp, M. G., Leth-Larsen, R., Ditzel, H., Hood, B. L. & Conrads, T. P., 4. maj 2018.

  Publikation: Konferencebidrag uden forlag/tidsskrift › Poster › Formidling
• 2016

  CDK6 as a predictive marker of response to fulvestrant treatment and a potential indicator of benefit from CDK4/6 inhibitor therapy in estrogen receptor-positive metastatic breast cancer

  Alves, C. M. L., Elias, D., Lyng, M. B., Bak, M., Lykkesfeldt, A. E. & Ditzel, H., 9. jul. 2016.

  Publikation: Konferencebidrag uden forlag/tidsskrift › Poster › Forskning › peer review

• Dual epitope targeting of CD73 exhibits potent anti-cancer activity

  Gammelgaard, O. L., Terp, M. G., Parren, P. W. H. I., Leth-Larsen, R. & Ditzel, H., 2016.

  Publikation: Konferencebidrag uden forlag/tidsskrift › Poster › Forskning

• Robust and on-line multi-omics de novo pathway enrichment with KeyPathwayMiner

  Alcaraz, N., List, M., Dissing-Hansen, M., Rehmsmeier, M., Tan, Q., Mollenhauer, J., Ditzel, H. & Baumbach, J., 2016.

  Publikation: Konferencebidrag uden forlag/tidsskrift › Poster › Forskning › peer review

  Åben adgang

• S100A14 increases tumorigenesis in triple-negative breast cancer

  Ehmsen, S., Nørgaard, K., Ditzel, H. & Leth-Larsen, R., 9. jul. 2016.

  Publikation: Konferencebidrag uden forlag/tidsskrift › Poster › Forskning

  Åben adgang
• 2015

  DEN-50R - establisment of a novel and unique cell line based drug screening platform for cancer treatment

  Stenvang, J., Moreira, J. M. A., Jensen, N. F., Nielsen, S. L., Orntoft, T., Lassen, U., Hansen, S. N., Jandu, H., Andreasen, M., Noer, J. B., Silva Lima, T., Viuff, B. M., Brunak, S., Jensen, P. B., Drejer, J., Ditzel, H. & Brünner, N., 2015.

  Publikation: Konferencebidrag uden forlag/tidsskrift › Poster › Forskning › peer review

• High expression of CDK6 confers resistance to fulvestrant in breast cancer cells and is a potential predictor of fulvestrant treatment failure in estrogen receptor-positive breast cancer

  Alves, C. M. L., Elias, D., Lyng, M. B., Bak, M., Lykkesfeldt, A. E. & Ditzel, H., 7. feb. 2015.

  Publikation: Konferencebidrag uden forlag/tidsskrift › Poster › Forskning › peer review

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• High expression of CDK6 protects breast cancer cells from fulvestrant-mediated apoptosis and is a predictor of resistance to fulvestrant treatment in estrogen receptor-positive metastatic breast cancer

  Alves, C. M. L., Elias, D., Lyng, M. B., Bak, M., Lykkesfeldt, A. & Ditzel, H., 2015.

  Publikation: Konferencebidrag uden forlag/tidsskrift › Poster › Forskning › peer review

• High expression of SNAI2 is associated with the emergence of a highly motile fulvestrantresistant phenotype and is an indicator of poor response to endocrine treatment in estrogen receptorpositive metastatic breast cancer

  Alves, C. M. L., Elias, D., Lyng, M. B., Bak, M., Lykkesfeldt, A. & Ditzel, H., 2015.

  Publikation: Konferencebidrag uden forlag/tidsskrift › Poster › Forskning › peer review

• IP-10 is an important chemokine secreted by tumor infiltrating lymphocytes and is an independent prognostic factor in triple-negative breast cancer patients

  Elias, D., Ditzel, H., Kupisiewicz, K., Jacobsen, K., Johansen, L. E. & Bak, M., 2015. 1 s.

  Publikation: Konferencebidrag uden forlag/tidsskrift › Poster › Forskning › peer review

• KeyPathwayMiner - De-novo network enrichment by combining multiple OMICS data and biological networks

  Baumbach, J., Alcaraz, N., Pauling, J. K., Batra, R., Vieira Barbosa, E. G., Christensen, A. G. L. & Ditzel, H., 10. jul. 2015.

  Publikation: Konferencebidrag uden forlag/tidsskrift › Poster › Forskning › peer review

  • Optimization Problem 100%
  • Search Space 100%
  • Subnetwork 100%

• Protein biomarkers predictive of outcome in EGFR inhibitor-treated non-small cell lung cancer patients with EGFR wildtype

  Jacobsen, K., Hood, B. L., Olsen, K. E., Conrads, T. P. & Ditzel, H., 2015.

  Publikation: Konferencebidrag uden forlag/tidsskrift › Poster › Forskning › peer review

• Quantitative proteomics identifies central players in erlotinib resistance of the non-small cell lung cancer cell line HCC827

  Jacobsen, K., Lund, R. R., Beck, H. C. & Ditzel, H., 1. mar. 2015. 1 s.

  Publikation: Konferencebidrag uden forlag/tidsskrift › Poster › Forskning › peer review

  • Quantitative Proteomics 100%
  • Cancer Cell 100%
  • Erlotinib 100%
  • Epidermal Growth Factor Receptor 57%
  • Cell Proliferation 14%

• Quantitative proteomics of formalin-fixed paraffin-embedded, primary triple-negative breast cancer tissues of patients who experienced distant metastasis or no recurrence

  Pedersen, M. H., Hood, B. L., Conrads, T. P., Ditzel, H. & Leth-Larsen, R., 2015.

  Publikation: Konferencebidrag uden forlag/tidsskrift › Poster › Forskning › peer review

• Resistance mechanisms to erlotinib in the non-small cell lung cancer cell line, HCC827 examined by RNA-seq

  Jacobsen, K., Alcaraz, N. & Ditzel, H., 7. feb. 2015. 1 s.

  Publikation: Konferencebidrag uden forlag/tidsskrift › Poster › Forskning › peer review

  • Cancer Cell 100%
  • Erlotinib 100%
  • RNA Sequencing 100%
  • Non Small Cell Lung Cancer 100%
  • Epidermal Growth Factor Receptor 45%
• 2014

  Global gene expression analysis of tamoxifen-resistant breast cancer cell lines identified a gene signature predictive of clinical outcome of breast cancer patients treated with endocrine therapy

  Elias, D., (Hansen) Vever, H., Lykkesfeldt, A. & Ditzel, H., 2014.

  Publikation: Konferencebidrag uden forlag/tidsskrift › Poster › Forskning › peer review

• Identification of resistance mechanisms in erlotinib-resistant subclones of the non-small cell lung cancer cell line HCC827 by exome sequencing

  Jacobsen, K., Alcaraz, N., Lund, R. R. & Ditzel, H., 9. okt. 2014. 1 s.

  Publikation: Konferencebidrag uden forlag/tidsskrift › Poster › Forskning › peer review

  • Cancer Cell 100%
  • Exome Sequencing 100%
  • Erlotinib 100%
  • Exome 33%
  • Epidermal Growth Factor Receptor 22%
• 2013

  Functional aspects of decreased bone marrow plasma concentrations of decorin in patients with MGUS and multiple myeloma

  Kristensen, I. B., Pedersen, L., Rø, T. B., Christensen, J. H., Lyng, M. B., Rasmussen, L. M., Ditzel, H. J., Børset, M. & Abildgaard , N., 14. apr. 2013.

  Publikation: Konferencebidrag uden forlag/tidsskrift › Poster › Forskning

• Gene expression of bone modulators in whole bone marrow biopsies in correlation to dynamic bone markers in multiple myeloma bone disease

  Kristensen, I. B., Christensen, J. H., Lyng, M. B., Ditzel, H. & Abildgaard , N., 14. jun. 2013.

  Publikation: Konferencebidrag uden forlag/tidsskrift › Poster › Forskning

• Gene expression profiling identified FYN as an omportant gene in tamoxifen resistance and a predictor of early recurrence in patients treated with endocrine therapy

  Elias, D., Ditzel, H. & Vever, H., 2013.

  Publikation: Konferencebidrag uden forlag/tidsskrift › Poster › Forskning › peer review

• S100A14: A Novel Prognostic Biomarker of Triple-Negative Breast Cancer Subtype

  Ehmsen, S., Bak, M., Ditzel, H. & Leth-Larsen, R., 25. jun. 2013.

  Publikation: Konferencebidrag uden forlag/tidsskrift › Poster › Forskning

• Set-up of Mouse Models for Nanodrug Testing

  Hansen, P. L., Riedel, A., Schmidt, S., Terp, M. G., Trojnar, J. H., Schifter, S., Olsen, B. B., Thisgaard, H., Ditzel, H., Høilund-Carlsen, P. F. & Mollenhauer, J., 2013.

  Publikation: Konferencebidrag uden forlag/tidsskrift › Poster › Forskning › peer review
• 2012

  Expression of Factors in the Hepatocyte Growth Factor (HGF) Pathway in Whole Bone Marrow Biopsies in Association to the Osteolytic Bone Disease of Multiple Myeloma

  Kristensen, I. B., Christensen, J. H., Lyng, M. B., Pedersen, L., Rasmussen, L. M., Ditzel, H. & Abildgaard , N., 2012.

  Publikation: Konferencebidrag uden forlag/tidsskrift › Poster › Forskning

• Expression of Wnt-Inhibitors and SDF-1in Whole Bone Marrow Biopsies in Association to the Osteolytic Bone Disease of Multiple Myeloma

  Kristensen, I. B., Christensen, J. H., Lyng, M. B., Pedersen, L., Rasmussen, L. M., Ditzel, H. & Abildgaard , N., 2012.

  Publikation: Konferencebidrag uden forlag/tidsskrift › Poster › Forskning

• Gene expression profile that predict outcome of Tamoxifen-treated estrogen receptor-positive, high-risk, primary breast cancer patients: a DBCG study

  Lyng, M. B., Lænkholm, A. V., Tan, Q., Vach, W., Gravgaard, K. H., Knoop, A. & Ditzel, H., 7. dec. 2012.

  Publikation: Konferencebidrag uden forlag/tidsskrift › Poster › Forskning

• Heterogeneity within the Cancer Stem Cell Population of the Triple-Negative Breast Cancer Subtype

  Ehmsen, S., Christensen, A. G. L., Ditzel, H. & Leth-Larsen, R., 7. jul. 2012.

  Publikation: Konferencebidrag uden forlag/tidsskrift › Poster › Forskning

• Identification of Markers Associated with Highly Aggressive Metastatic Phenotypes Using Quantitative Comparative Proteomics

  Terp, M. G., Lund, R. R., Jensen, O. N., Leth-Larsen, R. & Ditzel, H., 29. nov. 2012.

  Publikation: Konferencebidrag uden forlag/tidsskrift › Poster › Forskning › peer review

• Kinomic and phospho-proteomic analysis of breast cancer stem-like cells

  Leth-Larsen, R., Christensen, A. G. L., Ehmsen, S., Møller, M., Palmisano, G., Larsen, M. R. & Ditzel, H., 5. dec. 2012.

  Publikation: Konferencebidrag uden forlag/tidsskrift › Poster › Forskning
• 2011

  Absolute Quantitative Protein Profiling of Colon Tumors and Adjacent, Morphologically Normal Epithelial Tissue by Label-Free Mass Spectrometry

  Lund, R. R., Sprenger, R. R., Hansen, T. P., Jensen, O. N. & Ditzel, H., 20. jun. 2011.

  Publikation: Konferencebidrag uden forlag/tidsskrift › Poster › Forskning

• Antibodies targeting human CD73 inhibit breast tumor growth

  Terp, M. G., Fredberg, L., Lund, R. R., Skjødt, K., Ditzel, H. & Leth-Larsen, R., 9. mar. 2011.

  Publikation: Konferencebidrag uden forlag/tidsskrift › Poster › Forskning

• Association between the expression of secreted frizzled related protein 3 (SFRP3) DICKKOPF1 (DKK1) and the osteolytic bone disease (OBD) in multiple myeloma (MM)

  Kristensen, I. B., Christensen, J. H., Lyng, M. B., Klausen, T. W., Meldgaard Knudsen, L., Dahl, I. M., Rasmussen, T., Ditzel, H. & Abildgaard , N., 2011.

  Publikation: Konferencebidrag uden forlag/tidsskrift › Poster › Forskning › peer review

• Construction of new cancer cell models for nanodrug discovery and testing

  Hansen, P. L., Olsen, S. B., Terp, M. G., Schmidt, S., Riedel, A., Müller, C., Block, I., Christiansen, H., Ditzel, H. & Mollenhauer, J., 23. maj 2011.

  Publikation: Konferencebidrag uden forlag/tidsskrift › Poster › Forskning › peer review

• GAGE cancer-germline antigens bind DNA and are recruited to the nuclear envelope by Germ cell-less

  Bidragets oversatte titel: GAGE proteiner binder DNA og rekrutteres til kernemembranen af GCLGjerstorff, M., Rösner, H., Pedersen, C. B., Greve, K. B. V., Schmidt, S., Wilson, K., Mollenhauer, J., Besir, H., Poulsen, F., Møllegaard, N. E. & Ditzel, H., 5. dec. 2011.

  Publikation: Konferencebidrag uden forlag/tidsskrift › Poster › Forskning

• Global miRNA expression profiling of high-risk estrogen receptor-positive breast cancer patients treated with Tamoxifen

  Bidragets oversatte titel: Global miRNA expression profilering af høj-risiko østrogen receptor-positive brystkræft patienter behandlet med TamoxifenLyng, M. B., Lænkholm, A. V., Søkilde, R., Gravgaard, K. H., Litman, T. & Ditzel, H., 2011.

  Publikation: Konferencebidrag uden forlag/tidsskrift › Poster › Forskning

• Heterogeneity within the cancer stem cell population as defined by CD44⁺/CD24^low/- in breast cancer

  Leth-Larsen, R., Terp, M. G., Christensen, A. G. L., Elias, D., Kühlwein, T., Jensen, O. N., Petersen, O. W. & Ditzel, H., 6. mar. 2011.

  Publikation: Konferencebidrag uden forlag/tidsskrift › Poster › Forskning

• Multiple myeloma plasma cell (MM PC) co-expression of hepatocyte growth factor (HGF) isoforms and of the receptor cMET is associated with overall survial (OS) in MM patients

  Kristensen, I. B., Christensen, J. H., Lyng, M. B., Klausen, T. W., Meldgaard Knudsen, L., Dahl, I. M., Rasmussen, T., Ditzel, H. & Abildgaard , N., 2011.

  Publikation: Konferencebidrag uden forlag/tidsskrift › Poster › Forskning › peer review

• Potential underlying EMT mechanisms identified by global miRNA expression profiling of Tamoxifen-treated breast cancer patients

  Bidragets oversatte titel: Potentielle underliggende EMT-mekanismer identificeret ved global miRNA ekspressionsprofilering af Tamoxifen-behandlet brystkræft patienterLyng, M. B., Lænkholm, A. V., Søkilde, R., Gravgaard, K. H., Litman, T. & Ditzel, H., 6. mar. 2011.

  Publikation: Konferencebidrag uden forlag/tidsskrift › Poster › Forskning

• Quantitative Proteome Analysis of Cancer Tissues using SILAC-labeled Proteins of Multiple Histogenic Origins

  Lund, R. R., Terp, M. G., Jensen, O. N., Leth-Larsen, R. & Ditzel, H., 20. jun. 2011.

  Publikation: Konferencebidrag uden forlag/tidsskrift › Poster › Forskning

• The cancer-germline antigen SSX2 causes cell cycle arrest and DNA damage in cancer cells

  Bidragets oversatte titel: Cancer-kønscelle antigenet SSX2 medfører celle cyklus arrest og DNA skader i cancer cellerGreve, K. B. V., Lindgreen, J., Terp, M. G., Schmidt, S., Mollenhauer, J., Ditzel, H. & Gjerstorff, M., okt. 2011. 1 s.

  Publikation: Konferencebidrag uden forlag/tidsskrift › Poster › Forskning

• The phosphoproteome of breast cancer stem cells as determined by mass spectrometry

  Christensen, A. G. L., Palmisano, G., Leth-Larsen, R., Larsen, M. R. & Ditzel, H., 7. mar. 2011.

  Publikation: Konferencebidrag uden forlag/tidsskrift › Poster › Forskning
• 2010

  CD44 Variant Isoforms in Triple-Negative Breast Cancer

  Leth-Larsen, R., Christensen, A. G. L., Terp, M. G., Hansen, H. V., Petersen, O. W. & Ditzel, H., 2010.

  Publikation: Konferencebidrag uden forlag/tidsskrift › Poster › Forskning

• Protein Profiling of Primary Tumors with Different Abilities to Establish Lung Metastases

  Lund, R. R., Terp, M. G., Leth-Larsen, R., Jensen, O. N. & Ditzel, H., 2010.

  Publikation: Konferencebidrag uden forlag/tidsskrift › Poster › Forskning
• 2009

  Discriminating highly similar cancer cell lines using Raman spectroscopy and PLS-DA

  Hedegaard, M. A. B., Krafft, C., Johansen, L. E., Ditzel, H., Hassing, S. & Popp, J., 2009.

  Publikation: Konferencebidrag uden forlag/tidsskrift › Poster › Forskning

• ER status measured by FISH is a better predictor of prognosis in ER positive, postmenopausal breast cancer patients treated with adjuvant tamoxifen than ER status measured by RE-qPCR or IHC

  Lyng, M. B., Vang, K., Knoop, A., Ditzel, H., Lykkesfeldt, A. E., Müller, S. & Lænkholm, A. V., 2009.

  Publikation: Konferencebidrag uden forlag/tidsskrift › Poster › Forskning

• Gene expression profiles of tumor infiltrating lymphocytes from medullary breast cancer

  Jacobsen, K., Lænkholm, A. V., Tan, Q. & Ditzel, H., 2009.

  Publikation: Konferencebidrag uden forlag/tidsskrift › Poster › Forskning

• TIMP-1 status measured by immunohistochemistry in 268 ER positive postmenopausal high-risk breast cancer patients treated with adjuvant Tamoxifen: association to recurrence free survival

  Bjerre, C., Knoop, A., Lyng, M. B., Ditzel, H., Brünner, N., Bartels, A. & Lænkholm, A. V., 2009.

  Publikation: Konferencebidrag uden forlag/tidsskrift › Poster › Forskning
• 2008

  Mass Spectrometry-based Identification of Novel Protein Markers Associated with Metastasis

  Lund, R., Leth-Larsen, R., Hansen, H. V., Lænkholm, A. V., Tarin, D., Jensen, O. N. & Ditzel, H., 2008.

  Publikation: Konferencebidrag uden forlag/tidsskrift › Poster › Forskning
• 2007

  Distribution of nuclear eEF1A in normal and cancerous tissue, as detected by a human recombinant Fab fragment

  Lindgreen, J., Bonde-Poulsen, T. & Ditzel, H., 2007.

  Publikation: Konferencebidrag uden forlag/tidsskrift › Poster › Forskning