1988 …2020

Research output per year

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Personlig profil

Forskningsområde

Henrik J. Ditzel is Professor and Head of Research at Cancer and Inflammation Research Unit, Institute of Molecular Medicine, University of Southern Denmark, and Head of Research, Professor of Precision Medicine, and Senior Consultant at the Department of Oncology, Odense University Hospital, and Institute of Clinical Research, University of Southern Denmark. He is also an Adjunct Professor at The Scripps Research Institute, La Jolla, CA, USA and Visiting Professor at Tianjin Medical University Cancer Institute and Hospital in China.

Dr. Ditzel obtained his MD at the University of Odense in 1987. He received his PhD in Cancer immunology in 1992 and defended his medical doctorial thesis (DMSc) at University of Odense in 1999. He has spent 10 years at the prestigious U.S. research institution, The Scripps Research Institute, La Jolla, California, where he held positions as Assistant and Associate Professor and headed several NIH grants. Concurrently with his research effort, Dr. Ditzel completed his clinical training in Clinical Immunology at University of California, Diego (UCSD) Medical Center and became board certified in Histocompatibility and Immunogenetics (ABHI) in 2001. He obtained his California State license in 2002 and served as Associate Clinical professor and Associate clinical Director at the Histocompatibility and Immunogenetics laboratory at UCSD Medical Center.

Since 2003 Dr. Ditzel is Professor at University of Southern Denmark, where he heads a large (20+) translational cancer research group. His primary research interests include breast cancer, precision medicine, drug resistance mechansims, predictive and prognostic biomarker, cancer immunity, cancer stem cells, dissection of the metastasis process, cancer/testis antigens, and targeted therapies. Dr. Ditzel also play a central role in the genomic precision oncology program at Odense University Hospital.

Dr. Ditzel has been a member of NIH study sections and the American Arthritis Foundation Grant Review Board, the Biomedical panel of The Irish Science Foundation and he has reviewed grants from several public and private foundation in the US and Europe. Dr. Ditzel has chaired the Danish Cancer Society Scientific committee (2013-15) and the Danish Cancer Research Foundation (2013-15), and served as a member of these committees for additional 3 years.

He has published more than 160 scientific articles, most regarding cancer and in very prestigious journals, such as Nature Medicine, Nature Immunology, Nature Clinical Practice in Oncology, Nature Communications, Journal Clinical Investigation, JAMA Oncology, and Journal of Experimental Medicine, and given 100+ international invited oral presentations.

He has received several awards and honors, including the Danish Society for Cancer Research Honorary prize in 2011, Research Result of the Year in 2014, Knight of the Order of Dannebrog in 2015, and he was elected member of American Society of Clinical Investigation in 2003.

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Publikationer

ARAP1 is an independent prognostic biomarker in older women with ovarian high-grade serous adenocarcinoma receiving first-line platinum-based antineoplastic therapy

On behalf of Academy of Geriatric Cancer Research (AgeCare), 2. jan. 2020, I : Acta Oncologica. 59, 1, s. 40-47

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  • AXL Targeting Abrogates Autophagic Flux and Induces Immunogenic Cell Death in Drug-Resistant Cancer Cells

    Lotsberg, M. L., Wnuk-Lipinska, K., Terry, S., Tan, T. Z., Lu, N., Trachsel-Moncho, L., Røsland, G. V., Siraji, M. I., Hellesøy, M., Rayford, A., Jacobsen, K., Ditzel, H. J., Vintermyr, O. K., Bivona, T. G., Minna, J., Brekken, R. A., Baguley, B., Micklem, D., Akslen, L. A., Gausdal, G. & 5 flere, Simonsen, A., Thiery, J. P., Chouaib, S., Lorens, J. B. & Engelsen, A. S. T., 1. jan. 2020, I : Journal of Thoracic Oncology.

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

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  • Correction: VersicanV1 promotes proliferation and metastasis of hepatocellular carcinoma through the activation of EGFR–PI3K–AKT pathway (Oncogene, (2018), 37, 41, (5585-5586), 10.1038/s41388-018-0495-6)

    Elias, D., Vever, H., Lænkholm, A. V., Gjerstorff, M. F., Yde, C. W., Lykkesfeldt, A. E. & Ditzel, H. J., mar. 2020, I : Oncogene. 39, 10, s. 2229-2230

    Publikation: Bidrag til tidsskriftKommentar/debatForskningpeer review

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    Overexpression of HMGA2 in breast cancer promotes cell proliferation, migration, invasion and stemness

    Mansoori, B., Duijf, P. H. G., Mohammadi, A., Najafi, S., Roshani, E., Shanehbandi, D., Hajiasgharzadeh, K., Shirjang, S., Ditzel, H. J., Kazemi, T., Mokhtarzadeh, A., Gjerstorff, M. F. & Baradaran, B., 3. mar. 2020, I : Expert Opinion On Therapeutic Targets. 24, 3, s. 255-265

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  • Replication and ribosomal stress induced by targeting pyrimidine synthesis and cellular checkpoints suppress p53-deficient tumors

    Hubackova, S., Davidova, E., Boukalova, S., Kovarova, J., Bajzikova, M., Coelho, A., Terp, M. G., Ditzel, H. J., Rohlena, J. & Neuzil, J., 1. feb. 2020, I : Cell Death and Disease. 11, 2, 16 s., 110.

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

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  • 17 Downloads (Pure)

    Aktiviteter

    Oplæg

    Henrik Ditzel (Oplægsholder)
    17. jun. 2019

    Aktivitet: Foredrag og mundtlige bidragForedrag og præsentationer i privat eller offentlig virksomhed

    Foredrag

    Henrik Ditzel (Foredragsholder)
    13. jun. 2019

    Aktivitet: Foredrag og mundtlige bidragForedrag og præsentationer i privat eller offentlig virksomhed

    American Association of Clinical Oncology (ASCO) Annual Meeting

    Henrik Ditzel (Deltager)
    31. maj 20194. jun. 2019

    Aktivitet: Deltagelse i faglig begivenhedOrganisering af eller deltagelse i konference

    Foredrag

    Henrik Ditzel (Foredragsholder)
    21. mar. 2019

    Aktivitet: Foredrag og mundtlige bidragKonferenceoplæg

    Symposium: Kræftens Bekæmpelse

    Henrik Ditzel (Deltager)
    23. okt. 2017

    Aktivitet: Deltagelse i faglig begivenhedOrganisering af eller deltagelse i konference

    Priser

    Prestigefyldt Kræftforskningspris 2011

    Henrik Ditzel (Modtager), 6. maj 2011

    Pris: Priser, stipendier, udnævnelser