Erik Bjerregaard Pedersen

Søgeresultater

• 2020

  Evaluation of the Base-Pairing Properties of 5-(5-Indolylethynyl) and 5-(5-Indolyl)-2′-deoxyuridine Modified Triplex and Duplex

  Fatthalla, M. I. & Pedersen, E. B., 31. aug. 2020, I: ChemistrySelect. 5, 32, s. 10067-10071

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

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  Fil

  • Indole 100%
  • Oligonucleotide 94%
  • Electrophilic Substitution 32%
  • Ethynyl 31%
  • Matrix Assisted Laser Desorption Ionization - Time of Flight (MALDI-TOF) 30%
  11 Downloads (Pure)

• Role of Poly [ADP-ribose] Polymerase 1 in Activating the Kirstenras (KRAS) Gene in Response to Oxidative Stress

  Cinque, G., Ferino, A., Pedersen, E. B. & Xodo, L. E., 2020, I: International Journal of Molecular Sciences . 21, 17, s. 22 6237.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

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  Fil

  • Oxidative stress 100%
  • Administrative data processing 89%
  • Poly (ADP-Ribose) Polymerase-1 79%
  • Poly(ADPribose) 78%
  • adenosine diphosphate 77%
  23 Downloads (Pure)

• Synthesis, characterization and docking study of novel pyrimidine derivatives as anticancer agents

  El-Saidi, M. M. T., El-Sayed, A. A., Pedersen, E. B., Tantawy, M. A., Mohamed, N. R. & Gad, W. A., 2020, I: Indonesian Journal of Chemistry. 20, 5, s. 1163-1177

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

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  • Pyrimidine 100%
  • Antineoplastic Agent 99%
  • Thiouracil 85%
  • Guanine 54%
  • Thiourea 53%
  60 Downloads (Pure)
• 2019

  Conjugation of N-(3-(9-Ethynyl-6H-indolo[2,3-b]quinoxalin-6-yl)propyl)-2,2,2-trifluoroacetamide Intercalator to a Triplex Forming Oligonucleotide, a Three-Way Junction, and a G-Quadruplex

  Osman, A. M. A. & Pedersen, E. B., 23. jul. 2019, I: European Journal of Organic Chemistry. 2019, 27, s. 4362-4371

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

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  Fil

  • Oligonucleotide 100%
  • Monomer 66%
  • Phosphoramidite 33%
  • Ethynyl 33%
  • Trifluoroacetate 33%
  100 Downloads (Pure)

• Liposomes Decorated with G-Quadruplex Decoy Oligonucleotides: Their Nanoparticle Delivery and Efficient Bioactivity in Pancreatic Cancer Cells

  Pedersen, E. B., Vogel, S. & Xodo, L. E., 2019, s. 69-71. 2 s.

  Publikation: Konferencebidrag uden forlag/tidsskrift › Konferenceabstrakt til konference › Forskning

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• 2018

  Asymmetric Synthesis of Potential Precursors of the HIV Drug MC1220 and Its Analogues by Hydrogenation of (1-Arylvinyl)pyrimidines

  Loksha, Y. M. & Pedersen, E. B., 2018, I: Journal of Heterocyclic Chemistry. 55, 6, s. 1352-1357

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Pyrimidine 100%
  • Hydrogenation 82%
  • Drug 59%
  • Reduction 50%
  • Double Bond 34%

• The regulatory G4 motif of the Kirsten ras (KRAS) gene is sensitive to guanine oxidation: implications on transcription

  Cogoi, S., Ferino, A., Miglietta, G., Pedersen, E. B. & Xodo, L. E., 2018, I: Nucleic Acids Research. 46, 2, s. 661–676

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

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  Fil

  • G-Quadruplexes 100%
  • ras Genes 82%
  • Guanine 81%
  • Heterogeneous Nuclear Ribonucleoprotein A1 55%
  • dimethyl sulfate 54%
  177 Downloads (Pure)
• 2017

  Corrigendum to "PNA-COMBO-FISH: From combinatorial probe design in silico to vitality compatible, specific labelling of gene targets in cell nuclei" [Exp. Cell Res. 345 (2016) 51-59]

  Müller, P., Rößler, J., Schwarz-Finsterle, J., Pedersen, E. B., Géci, I., Schmitt, E. & Hausmann, M., 15. jun. 2017, I: Experimental Cell Research. 355, 2, s. 194-195 2 s.

  Publikation: Bidrag til tidsskrift › Kommentar/debat › Forskning › peer review

• Improved i-motif thermal stability by insertion of anthraquinone monomers

  Gouda, A. S., Amine, M. S. & Pedersen, E. B., 2017, I: Organic & Biomolecular Chemistry. 15, 31, s. 6613-6621

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • anthraquinones 100%
  • Anthraquinones 92%
  • Anthraquinone 71%
  • insertion 63%
  • monomers 60%

• LNA effects on DNA binding and conformation: from single strand to duplex and triplex structures

  Pabon-Martinez, Y. V., Xu, Y., Villa, A., Lundin, K. E., Geny, S., Nguyen, C-H., Pedersen, E. B., Jørgensen, P. T., Wengel, J., Nilsson, L., Smith, C. I. E. & Zain, R., 2017, I: Scientific Reports. 7, 1, 16 s., 11043.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

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  Fil

  • locked nucleic acid 100%
  • Nucleic Acid Conformation 95%
  • Oligonucleotides 67%
  • triplex DNA 21%
  • frataxin 20%
  232 Downloads (Pure)

• Synthesis and Molecular Modeling of Thermally Stable DNA G-Quadruplexes with Anthraquinone Insertions

  Gouda, A. S., Amine, M. S. & Pedersen, E. B., 2017, I: European Journal of Organic Chemistry. 2017, 21, s. 3092-3100

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Anthraquinone 100%
  • Molecular Modeling 82%
  • Monomer 53%
  • Phosphoramidite 27%
  • Alkylation 19%
• 2016

  Facile synthesis of the NNRTI microbicide MC-1220 and synthesis of its phosphoramidate prodrugs

  Loksha, Y. M., Pedersen, E. B., La Colla, P. & Loddo, R., 2016, I: Organic & Biomolecular Chemistry. 14, 3, s. 940-946

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • 6-(1-(2,6-difluorophenyl)ethyl)-2-(dimethylamino)-5-methylpyrimidin-4(3H)-one 100%
  • phosphoramidic acid 72%
  • Phosphoramidate 56%
  • Prodrugs 46%
  • Prodrug 44%

• Lipid-modified G4-decoy oligonucleotide anchored to nanoparticles: delivery and bioactivity in pancreatic cancer cells

  Cogoi, S., Jakobsen, U., Pedersen, E. B., Vogel, S. & Xodo, L. E., 8. dec. 2016, I: Scientific Reports. 6, s. 1-13 38468.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

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  Fil

  • Oligonucleotides 100%
  • Pancreatic Neoplasms 90%
  • Nanoparticles 85%
  • Cell-Penetrating Peptides 66%
  • Lipids 62%
  222 Downloads (Pure)

• Next-generation bis-locked nucleic acids with stacking linker and 2'-glycylamino-LNA show enhanced DNA invasion into supercoiled duplexes

  Geny, S., Moreno, P. M. D., Krzywkowski, T., Gissberg, O., Andersen, N. K., Isse, A. J., El-Madani, A. M., Lou, C., Pabon, Y. V., Anderson, B. A., Zaghloul, E. M., Zain, R., Hrdlicka, P. J., Jørgensen, P. T., Nilsson, M., Lundin, K. E., Pedersen, E. B., Wengel, J. & Smith, C. I. E., 18. mar. 2016, I: Nucleic Acids Research. 44, 5, s. 2007-2019

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

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  Fil

  • locked nucleic acid 100%
  • DNA 36%
  • Oligonucleotides 27%
  • Superhelical DNA 19%
  • Plasmids 10%
  352 Downloads (Pure)

• Synthesis and Anti-HIV-1 Evaluation of Some Novel MC-1220 Analogs as Non-Nucleoside Reverse Transcriptase Inhibitors

  Loksha, Y. M., Pedersen, E. B., Loddo, R. & La Colla, P., 2016, I: Archiv der Pharmazie. 349, 5, s. 363-372

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • 6-(1-(2,6-difluorophenyl)ethyl)-2-(dimethylamino)-5-methylpyrimidin-4(3H)-one 100%
  • Nonnucleoside Reverse Transcriptase Inhibitor 60%
  • Reverse Transcriptase Inhibitors 50%
  • Sodium Salt 41%
  • Sodium Hydroxide 39%

• Synthesis of New DNA G-Quadruplex Constructs with Anthraquinone Insertions and Their Anticoagulant Activity

  Gouda, A. S., Amine, M. S. & Pedersen, E. B., 2016, I: Helvetica Chimica Acta. 99, 2, s. 116-124

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

• Thermal Stability of Modified i-Motif Oligonucleotides with Naphthalimide Intercalating Nucleic Acids

  El-Sayed, A. A., Pedersen, E. B. & Khaireldin, N. Y., 1. jan. 2016, I: Helvetica Chimica Acta. 99, 1, s. 14-19

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Naphthalimides 100%
  • Oligonucleotides 79%
  • Nucleic acids 78%
  • oligonucleotides 74%
  • nucleic acids 70%

• Unexpected Hydration of a Triple Bond During DNA Synthesis: Conjugating 3-(Pyren-1-ylethynyl)indole to DNA for Triplex Studies

  Fatthalla, M. I. & Pedersen, E. B., 2016, I: European Journal of Organic Chemistry. 2016, 21, s. 3528-3535

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Triple Bond 100%
  • Indole 85%
  • Oligonucleotide 53%
  • Nucleic Acid 51%
  • Pyrene 29%
• 2015

  Anti-parallel triplexes: Synthesis of 8-aza-7-deazaadenine nucleosides with a 3-aminopropynyl side-chain and its corresponding LNA analog

  Kosbar, T. R., Sofan, M. A., Waly, M. A. & Pedersen, E. B., 15. maj 2015, I: Bioorganic & Medicinal Chemistry. 23, 10, s. 2458-2469

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • 8-aza-7-deazaadenine 100%
  • Nucleobase 48%
  • Nucleosides 47%
  • Nucleoside 41%
  • Hot Temperature 34%

• Design, synthesis and antimicrobial evaluation of novel carbendazim dithioate analogs

  Zahran, M. A. H., Osman, A. M. A., Wahed, R. A., Attia, M., Pedersen, E. B., Elnasser, G. A. & Turky, A. S., 2015, I: Research Journal of Pharmaceutical, Biological and Chemical Sciences. 6, 4, s. 1084-1092

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • carbendazim 100%
  • Carbendazim 82%
  • Fusarium 59%
  • Antimicrobial Agent 39%
  • Soil 24%

• GC-elements controlling HRAS transcription form i-motif structures unfolded by heterogeneous ribonucleoprotein particle A1

  Miglietta, G., Cogoi, S., Pedersen, E. B. & Xodo, L. E., 2015, I: Scientific Reports. 5, 18097.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

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  Fil

  • Heterogeneous Nuclear Ribonucleoprotein A1 100%
  • Ribonucleoproteins 75%
  • B-Form DNA 17%
  • G-Quadruplexes 14%
  • Transcription Initiation Site 11%
  136 Downloads (Pure)

• Nucleic Acid Targeted Therapy: G4 Oligonucleotides Downregulate HRAS in Bladder Cancer Cells through a Decoy Mechanism

  Miglietta, G., Gouda, A. S., Cogoi, S., Pedersen, E. B. & Xodo, L. E., 2015, I: A C S Medicinal Chemistry Letters. 6, 12, s. 1179–1183 5 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

• Synthesis of new bis-phthalimide and thalidomide ester derivatives, and evaluation of their cytotoxic activity

  Osman, A. M. A., Mansour, E. A. H., Zahran, M. A. H. & Pedersen, E. B., 2015, I: International Journal of Pharmaceutical Sciences Review and Research. 33, 2, s. 158-165

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • phthalimide 100%
  • Thalidomide 84%
  • phthalic anhydride 75%
  • Esters 55%
  • Phthalimide 45%

• Thermal stability of G-rich anti-parallel DNA triplexes upon insertion of LNA and α-l-LNA

  Kosbar, T. R., Sofan, M. A., Abou-Zeid, L. & Pedersen, E. B., 14. maj 2015, I: Organic & Biomolecular Chemistry. 13, 18, s. 5115-5121

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

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  Fil

  • triplex DNA 100%
  • pyrimidine 73%
  • strands 63%
  • insertion 58%
  • deoxyribonucleic acid 54%
  162 Downloads (Pure)
• 2014

  Synthesis and Evaluation of Novel 6(3,5Dimethylbenzyl)uracil Analogs as Potential AntiHIV1 Agents

  Khalifa, N. M., Pedersen, E. B., Nielsen, C. & A. Al-Omar, M., 2014, I: Russian Journal of Bioorganic Chemistry. 40, 5, s. 579-585 7 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

• Synthesis and evaluation of thalidomide and phthalimide esters as antitumor agents

  Zahran, M. A. H., Abdin, Y. G., Osman, A. M. A., Gamal-Eldeen, A. M., Talaat, R. M. & Pedersen, E. B., 20. jun. 2014, I: Archiv der Pharmazie. 347, 9, s. 642–649 8 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • phthalimide 100%
  • Thalidomide 84%
  • Phthalimide 68%
  • Esters 55%
  • Antineoplastic Agents 52%

• Synthesis of novel fluoro analogues of MKC442 as microbicides

  Loksha, Y. M., Pedersen, E. B., Loddo, R., Sanna, G., Collu, G., Giliberti, G. & Colla, P. L., 26. jun. 2014, I: Journal of Medicinal Chemistry. 57, 12, s. 5169-5178 10 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • RNA Directed DNA Polymerase Inhibitor 100%
  • Reverse Transcriptase Inhibitors 70%
  • 5-ethyluracil 62%
  • Anti-Infective Agents 60%
  • HIV-1 50%

• Unlocked nucleic acids with a pyrene-modified uracil: Synthesis, hybridization studies, fluorescent properties and i-motif stability

  Perlíková, P., Karlsen, K. K., Pedersen, E. B. & Wengel, J., 2014, I: ChemBioChem. 15, 1, s. 146-156

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • pyrene 100%
  • Uracil 89%
  • Nucleic Acids 68%
  • Nucleic Acid 58%
  • Monomer 41%
• 2013

  Development of bis-locked nucleic acid (bisLNA) oligonucleotides for efficient invasion of supercoiled duplex DNA

  Moreno, P. M. D., Geny, S., Pabon, Y. V., Bergquist, H., Zaghloul, E. M., Rocha, C. S. J., Oprea, I. I., Bestas, B., Andaloussi, S. E., Jørgensen, P. T., Pedersen, E. B., Lundin, K. E., Zain, R., Wengel, J. & Smith, C. I. E., 2013, I: Nucleic Acids Research. 41, 5, s. 3257-3273 17 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • locked nucleic acid 100%
  • Superhelical DNA 96%
  • Oligonucleotides 67%
  • DNA 20%
  • Salts 6%

• Highly Efficient Synthesis of Allopurinol Locked Nucleic Acid Monomer by C6 Deamination of 8-Aza-7-bromo-7-deazaadenine Locked Nucleic Acid Monomer

  Kosbar, T. R. E-S., Sofan, M., Abou-Zeid, L., Waly, M. & Pedersen, E. B., 2013, I: Synthesis. 45, 23, s. 3259-3262 4 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Locked Nucleic Acid 100%
  • Allopurinol 99%
  • Nucleic acids 98%
  • Monomers 79%
  • Deamination 78%

• MAZ-binding G4-decoy with locked nucleic acid and twisted intercalating nucleic acid modifications suppresses KRAS in pancreatic cancer cells and delays tumor growth in mice

  Cogoi, S., Zorzet, S., Rapozzi, V., Géci, I., Pedersen, E. B. & Xodo, L. E., 1. apr. 2013, I: Nucleic Acids Research. 41, 7, s. 4049-4064 16 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • locked nucleic acid 100%
  • Zinc Fingers 73%
  • Nucleic Acids 63%
  • Pancreatic Neoplasms 61%
  • Oligonucleotides 45%

• Synthesis of a new intercalating nucleic acid 6H-INDOLO[2,3-b] quinoxaline oligonucleotides to improve thermal stability of Hoogsteen-type triplexes

  Osman, A. M. A., Pedersen, E. B. & Bergman, J., 2013, I: Nucleosides, Nucleotides and Nucleic Acids. 32, 2, s. 98-108

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • butane-1,2-diol 100%
  • butane 81%
  • Quinoxalines 73%
  • phosphoramidite 63%
  • Quinoxaline 57%
• 2012

  Chemical maturation of a bivalent aptamer by single domain variation

  Rohrbach, F., Fatthalla, M. I., Kupper, T., Pötzsch, B., Müller, J., Petersen, M., Pedersen, E. B. & Mayer, G., 2012, I: ChemBioChem. 13, 5, s. 631-4 4 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Polycyclic Aromatic Hydrocarbons 100%
  • Arene 62%
  • Molecule 27%

• Conjugation of a 3-(1H-phenanthro[9,10-d]imidazol-2-yl)-1H-indole intercalator to a triplex oligonucleotide and to a three-way junction

  Fatthalla, M. I., Elkholy, Y. M., Abbas, N. S., Mandour, A. H., Jørgensen, P. T., Bomholt, N. & Pedersen, E. B., 2012, I: Bioorganic & Medicinal Chemistry Letters. 20, 1, s. 207-14 8 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • 1H-phenanthro(9,10-d)imidazole 100%
  • Intercalating Agents 63%
  • indole 52%
  • Oligonucleotides 41%
  • Oligonucleotide 35%

• Improved DNA clamps by stacking to adjacent nucleobases

  Fatthalla, M. I. & Pedersen, E. B., 1. sep. 2012, I: Helvetica Chimica Acta. 95, 9, s. 1538-1547 10 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Acetylene 100%
  • locked nucleic acid 95%
  • Locked Nucleic Acid 91%
  • clamps 74%
  • Clamping devices 69%

• Improved Inhibition of Telomerase by Short Twisted Intercalating Nucleic Acids under Molecular Crowding Conditions

  Agarwal, T., Pradhan, D., Géci, I., El-Madani, A. M., Petersen, M., Pedersen, E. B. & Maiti, S., 2012, I: Nucleic Acid Therapeutics. 22, 6, s. 399-404 6 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • G-Quadruplexes 100%
  • Crowding 94%
  • Telomerase 77%
  • Nucleic Acids 67%
  • Psychological Inhibition 55%

• STUDYING THE INFLUENCE OF THE PYRENE INTERCALATOR TINA ON THE STABILITY OF DNA i-MOTIFS

  El-Sayed, A. A., Pedersen, E. B. & Khaireldin, N. A., 2012, I: Nucleosides, Nucleotides and Nucleic Acids. 31, s. 872-879 8 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
• 2011

  Biomolecular Chemistry - third edition

  Kirpekar, F. (red.) & Pedersen, E. B. (red.), 2011, 3. udg. Harlow, England: Pearson Longman.

  Publikation: Bog/rapport › Monografi › Undervisning

• Cationic modified nucleic acids for use in DNA hairpins and parallel triplexes

  Bomholt, N., Filichev, V. V. & Pedersen, E. B., 2011, I: Organic & Biomolecular Chemistry. 9, s. 4527-4534

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • nucleic acids 100%
  • Nucleic Acids 75%
  • deoxyribonucleic acid 69%
  • Nucleic Acid 64%
  • Hot Temperature 44%

• Enhanced anti-HIV-1 activity of G-quadruplexes comprising locked nucleic acids and intercalating nucleic acids

  Pedersen, E. B., Nielsen, J. T., Nielsen, C. & Filichev, V. V., 2011, I: Nucleic Acids Research. 39, 6, s. 2470-2481 12 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

• G4-DNA Formation in the HRAS Promoter and Rational Design of Decoy Oligonucleotides for Cancer Therapy

  Membrino, A., Cogoi, S., Pedersen, E. B. & Xodo, L. E., 2011, I: P L o S One. 6, 9, s. e24421 16 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  Åben adgang

• Increasing the Analytical Sensitivity by Oligonucleotides Modified with Para- and Ortho-Twisted Intercalating Nucleic Acids - TINA

  Schneider, U. V., Géci, I., Jøhnk, N., Mikkelsen, N. D., Pedersen, E. B. & Lisby, G., 2011, I: P L o S One. 6, 6, s. e20565

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Oligonucleotides 100%
  • Nucleic Acids 94%
  • Intercalating Agents 50%
  • Osmolar Concentration 22%
  • phosphoramidite 20%

• Optimizing anti-gene oligonucleotide 'Zorro-LNA' for improved strand invasion into duplex DNA

  Zaghloul, E. M., Madsen, A. S., Moreno, P. M. D., Oprea, I. I., El-Andaloussi, S., Bestas, B., Gupta, P., Pedersen, E. B., Lundin, K. E., Wengel, J. & Smith, C. I. E., 1. feb. 2011, I: Nucleic Acids Research. 39, 3, s. 1142-54 13 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Oligonucleotides 100%
  • DNA 53%
  • Genes 38%
  • Carbon 37%
  • phosphoramidite 36%

• PYRENE INTERCALATING NUCLEIC ACIDS WITH A CARBON LINKER

  Østergaard, M. E., Wamberg, M. C. & Pedersen, E. B., 2011, I: Nucleosides, Nucleotides and Nucleic Acids. 30, s. 210-226 17 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

• Synthesis and Anti-HIV-1 Activity of New Fluoro-HEPT Analogues: An Investigation on Fluoro versus Hydroxy Substituents

  Loksha, Y. M., Pedersen, E. B., Loddo, R. & La Colla, P., 2011, I: Archiv der Pharmazie. 344, 6, s. 366-71 6 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Halogenation 100%
  • Uracil 96%
  • 5-benzyluracil 88%
  • propargyl alcohol 82%
  • Fluorination 80%

• Synthesis of locked pyranosyl nucleic acid (LpNA)

  Bomholt, N., Jørgensen, P. T. & Pedersen, E. B., 2011, I: Bioorganic & Medicinal Chemistry Letters. 21, 24, s. 7376-7378 3 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • locked nucleic acid 100%
  • Nucleosides 68%
  • Nucleoside 59%
  • Nucleic Acid 54%
  • Oligonucleotides 33%
• 2010

  A novel FRET pair for detection of parallel DNA triplexes by the LightCycler

  Schneider, U. V., Severinsen, J. K., Géci, I., Okkels, L. M., Jøhnk, N., Mikkelsen, N. D., Klinge, T., Pedersen, E. B., Westh, H. & Lisby, G., 2010, I: BMC Biotechnology. 10, 4, s. 1-12 12 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

• A Novel Synthetic Route for the Anti-HIV Drug MC-1220 and its Analogues

  Loksha, Y. M. A., Globisch, D., Loddo, R., Collu, G., La Colla, P. & Pedersen, E. B., 2010, I: ChemMedChem. 5, s. 1847-1849 3 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

• Synthesis of a new intercalating nucleic acid analogue with pyrenol insertions and the thermal stability of the resulting oligonucleotides towards DNA over RNA

  Osman, A. M. A. & Pedersen, E. B., 2010, I: Monatshefte für Chemie - Chemical Monthly. 141, s. 817-822 6 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Oligonucleotide 100%
  • Nucleic Acid 95%
  • Thermal Stability 74%
  • Monomer 66%
  • Mitsunobu Reaction 46%

• Tænk nyt om målsætningen for universitetsforskning

  Pedersen, E. B., 12. jul. 2010, I: Morgenavisen Jyllands-Posten.

  Publikation: Bidrag til tidsskrift › Bidrag til avis - Avisartikel › Formidling