20032019
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Publikationer 2003 2019

  • 33 Tidsskriftartikel
  • 18 Konferenceabstrakt i tidsskrift
  • 7 Poster
  • 2 Bidrag til bog/antologi
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Tidsskriftartikel
2019

Linked Hexokinase and Glucose-6-Phosphatase Activities Reflect Grade of Ovarian Malignancy

Olsen, B. B., Gjedde, A., Vilstrup, M. H., Johnsen, I. B. G., Neumann, G., Torigian, D. A., Alavi, A. & Høilund-Carlsen, P. F., apr. 2019, I : Molecular Imaging and Biology. 21, 2, s. 375-381

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Glucose-6-Phosphatase
Hexokinase
Ovarian Neoplasms
Neoplasms
Fluorodeoxyglucose F18
2018
23 Downloads (Pure)
Åben adgang
Fil
Cobalt
Neoplasms
Half-Life
Ligands
oleylamine
2017

A PSMA Ligand Labeled with Cobalt-55 for PET Imaging of Prostate Cancer

Dam, J. H., Olsen, B. B., Baun, C., Høilund-Carlsen, P. F. & Thisgaard, H., 2017, I : Molecular Imaging and Biology. 19, 6, s. 915–922

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Cobalt
Prostatic Neoplasms
Ligands
Heterografts
Neoplasms
100 Downloads (Pure)

Evaluation of somatostatin and nucleolin receptors for therapeutic delivery in non-small cell lung cancer stem cells applying the somatostatin-analog DOTATATE and the nucleolin-targeting aptamer AS1411

Holmboe, S., Hansen, P. L., Thisgaard, H., Block, I., Müller, C., Langkjær, N., Høilund-Carlsen, P. F., Olsen, B. B. & Mollenhauer, J., 2017, I : PLOS ONE. 12, 5, 12 s., e0178286.

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Somatostatin Receptors
somatostatin
lung neoplasms
Somatostatin
Stem cells
92 Downloads (Pure)

The use of radiocobalt as a label improves imaging of EGFR using DOTA-conjugated Affibody molecule

Garousi, J., Andersson, K. G., Dam, J. H., Olsen, B. B., Mitran, B., Orlova, A., Buijs, J., Ståhl, S., Löfblom, J., Thisgaard, H. & Tolmachev, V., 2017, I : Scientific Reports. 7, 10 s., 5961.

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Epidermal Growth Factor Receptor
Radioisotopes
Neoplasms
Cobalt Radioisotopes
Cobalt Isotopes
2016

Dual time-point FDG PET/CT and FDG uptake and related enzymes in lymphadenopathies: preliminary results

Christlieb, S. B., Nørgaard Strandholdt, C., Olsen, B. B., Mylam, K. J., Larsen, T. S., Nielsen, A. L., Rohde, M., Gerke, O., Olsen, K. E., Møller, M. B., Kristensen, B. W., Abildgaard, N., Alavi, A. & Høilund-Carlsen, P. F., sep. 2016, I : European Journal of Nuclear Medicine and Molecular Imaging. 43, 10, s. 1824-1836

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Hexokinase
Glycolysis
Glucose-6-Phosphatase
Enzymes
Lymphoma
129 Downloads (Pure)

Highly Effective Auger-Electron Therapy in an Orthotopic Glioblastoma Xenograft Model using Convection-Enhanced Delivery

Thisgaard, H., Halle, B., Aaberg-Jessen, C., Olsen, B. B., Nautrup Therkelsen, A. S., Dam, J. H., Langkjær, N., Munthe, S., Någren, K., Høilund-Carlsen, P. F. & Kristensen, B. W., 2016, I : Theranostics. 6, 12, s. 2278-2291

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In Vivo Evaluation of a Bombesin Analogue Labeled with Ga-68 and Co-55/57

Dam, J. H., Olsen, B. B., Baun, C., Høilund-Carlsen, P. F. & Thisgaard, H., 2016, I : Molecular Imaging and Biology. 18, 3, s. 368-376

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

2014

Evaluation of Cobalt-Labeled Octreotide Analogs for Molecular Imaging and Auger Electron-Based Radionuclide Therapy

Thisgaard, H., Olsen, B. B., Dam, J. H., Bollen, P., Mollenhauer, J. & Høilund-Carlsen, P. F., 29. maj 2014, I : Journal of Nuclear Medicine. 55, 8, s. 1311-1316

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Octreotide
Cobalt
Radioisotopes
Electrons
Therapeutic Uses

The basic principles of FDG-PET/CT imaging

Basu, S., Hess, S., Braad, P-E., Olsen, B. B., Inglev, S. & Høilund-Carlsen, P. F., 2014, I : P E T Clinics. 9, s. 355-70

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The protein kinase CK2(Andante) holoenzyme structure supports proposed models of autoregulation and trans-autophosphorylation

Schnitzler, A., Olsen, B. B., Issinger, O-G. & Niefind, K., 1. maj 2014, I : Journal of Molecular Biology. 426, 9, s. 1871-1882

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Casein Kinase II
Holoenzymes
Names
Homeostasis
bunazosin
2012

Characterization of ATM and DNA-PK wild-type and mutant cell lines upon DSB induction in the presence and absence of CK2 inhibitors

Olsen, B. B., Fritz, G. & Issinger, O-G., 2012, I : International Journal of Oncology. 40, 2, s. 592-598

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Protein kinase CK2 localizes to sites of DNA double-strand break regulating the cellular response to DNA damage

Olsen, B. B., Wang, S-Y., Svenstrup, T. H., Chen, B. P. C. & Guerra, B., 2012, I : B M C Molecular Biology. 13, s. 7-19

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Åben adgang
2011

Enzymatic activity with an incomplete catalytic spine: insights from a comparative structural analysis of human CK2α and its paralogous isoform CK2α'

Bischoff, N., Raaf, J., Olsen, B. B., Bretner, M., Issinger, O-G. & Niefind, K., 2011, I : Molecular and Cellular Biochemistry. 356, 1-2, s. 57-65

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Interaction between CK2α and CK2β, the Subunits of Protein Kinase CK2: Thermodynamic Contributions of Key Residues on the CK2α Surface

Raaf, J., Bischoff, N., Kloppfleisch, K., Brunstein, E., Olsen, B. B., Vilk, G., Litchfield, D., Issinger, O-G. & Niefind, K., 1. feb. 2011, I : Biochemistry. 50, 4, s. 512-22 11 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Casein Kinase II
Holoenzymes
Calorimetry
Titration
Phosphotransferases

Lack of the catalytic subunit of DNA-dependent protein kinase (DNA-PKcs) is accompanied by increased CK2a' levels

Olsen, B. B., Fischer, U., Rasmussen, T. D. L., Montenarh, M., Meese, E., Fritz, G. & Issinger, O-G., 2011, I : Molecular and Cellular Biochemistry. 356, 1-2, s. 139-147

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Role of polyamines in determining the cellular response to chemotherapeutic agents: modulation of protein kinase CK2 expression and activity

Kreutzer, J. N., Olsen, B. B., Lech, K., Issinger, O-G. & Guerra, B., 2011, I : Molecular and Cellular Biochemistry. 356, 1-2, s. 149-158

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Structure of the Human Protein Kinase CK2 Catalytic Subunit CK2α′ and Interaction Thermodynamics with the Regulatory Subunit CK2β

Bischoff, N., Olsen, B. B., Raaf, J., Bretner, M., Issinger, O-G. & Niefind, K., 2011, I : Journal of Molecular Biology. 407, 1, s. 1-12

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Casein Kinase II
Catalytic Domain
2010

Mapping of the interaction sites between Wee1 kinase and the regulatory ß-subunit of protein kinase CK2

Olsen, B. B., Kreutzer, J. N., Watanabe, N., Holm, T. & Guerra, B., 2010, I : International Journal of Oncology. 36, s. 1175-1182

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Regulation of DNA-dependent protein kinase by protein kinase CK2 in human glioblastoma cells

Olsen, B. B., Issinger, O-G. & Guerra, B., 2010, I : Oncogene. 29(45), s. 6016-26

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2009

Resorufin: a lead for a new protein kinase CK2 inhibitor

Sandholt, I. S., Olsen, B. B., Guerra, B. & Issinger, O-G., 1. apr. 2009, I : Anti-Cancer Drugs. 20, 4, s. 238-248 10 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Casein Kinase II
Protein Kinase Inhibitors
Emodin
Cell Line
HCT116 Cells

Selectivity analysis of protein kinase CK2 inhibitors DMAT, TBB and resorufin in cisplatin-induced stress responses

Fritz, G., Issinger, O-G. & Olsen, B. B., 1. nov. 2009, I : International Journal of Oncology. 35, 5, s. 1151-1157 6 s.

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Casein Kinase II
Protein Kinase Inhibitors
Cisplatin
Neoplasms
Cell Survival
2008

Ability of CK2beta to selectively regulate cellular protein kinases

Olsen, B. & Guerra, B., 2008, I : Molecular and Cellular Biochemistry. 316, 1-2, s. 115-126

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Casein Kinase II
beta-Transducin Repeat-Containing Proteins
Phosphorylation
Protein Kinases
CDC2 Protein Kinase
Holoenzymes
Catalytic Domain
Calmodulin
Emodin
Apigenin

Exploring the intramolecular phosphorylation sites in human Chk2

Olsen, B. B., Larsen, M. R., Boldyreff, B., Niefind, K. & Issinger, O-G., 10. nov. 2008, I : Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 646, 1-2, s. 50-59 9 s.

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Amino Acids
HEK293 Cells
Recombinant Proteins
Gel Chromatography
DNA

The regulatory beta-subunit of protein kinase CK2 regulates cell-cycle progression at the onset of mitosis

Yde, C. W., Olsen, B. B., Meek, D., Watanabe, N. & Guerra, B., 2008, I : Oncogene. 27, 37, s. 4986-4997

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CDC2 Protein Kinase
Casein Kinase II
Cell Cycle
Down-Regulation
Cyclin B
2007
Emodin
1-Phosphatidylinositol 4-Kinase
Phosphatidylinositols
Phosphotransferases
Cells

UV light blocks EGFR signalling in human cancer cell lines

Olsen, BB., Neves-Petersen, M. T., Klitgaard, S., Issinger, OG. & Petersen, S. B., 1. jan. 2007, I : International Journal of Oncology. 30, 1, s. 181-185 4 s.

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Ultraviolet Rays
Epidermal Growth Factor Receptor
Lighting
Cell Line
Phospho-Specific Antibodies
2006

BID, an interaction partner of protein kinase CK2alpha

Olsen, B. B., Petersen, J. & Issinger, O-G., 2006, I : Biological Chemistry. 387, 4, s. 441-449

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Purification and characterization of the CK2alpha' -based holoenzyme, an isozyme of CK2alpha: A comparative analysis

Olsen, B. B., Boldyreff, B., Niefind, K. & Issinger, O-G., 2006, I : Protein Expression and Purification. 47, 2, s. 651-661

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2003

Disruption of the regulatory beta subunit of protein kinase CK2 in mice leads to a cell-autonomous defect and early embryonic lethality

Buchou, T., Vernet, M., Blond, O., Jensen, H. H., Pointu, H., Olsen, B. B., Cochet, C., Issinger, O-G. & Boldyreff, B., 2003, I : Molecular and Cellular Biology. 23, 3, s. 908-915 7 s.

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Casein Kinase II
Mammals
Embryonic Structures
Morula
Gene Knockout Techniques

Protein kinase CK2 phosphorylates the Fas-associated factor FAF1 in vivo and influences its transport into the nucleus.

Olsen, B. B., Jessen, V., Højrup, P., Issinger, O-G. & Boldyreff, B., 10. jul. 2003, I : FEBS Letters. 546, 2-3, s. 218-22 4 s.

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Casein Kinase II
Phosphorylation
Cell Nucleus Active Transport
Serine
Apoptosis