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Publikationer 1993 2018

2018
116 Downloads (Pure)

Experimental demyelination and axonal loss are reduced in MicroRNA-146a deficient mice

Martin, N. A., Molnar, V., Szilagyi, G. T., Elkjaer, M. L., Nawrocki, A., Okarmus, J., Wlodarczyk, A., Thygesen, E. K., Palkovits, M., Gallyas, F., Larsen, M. R., Lassmann, H., Benedikz, E., Owens, T., Svenningsen, A. F. & Illes, Z., 2018, I : Frontiers in Immunology. 9, 14 s., 490.

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Demyelinating Diseases
Oligodendroglia
Corpus Callosum
Cuprizone
MicroRNAs
96 Downloads (Pure)

Expression and regulation of CYP17A1 and 3β-hydroxysteroid dehydrogenase in cells of the nervous system: Potential effects of vitamin D on brain steroidogenesis.

Emanuelsson, I., Almokhtar, M., Wikvall, K., Grönbladh, A., Nylander, E., Svensson, AL., Fex Svenningsen, Å. & Norlin, M., 2018, I : Neurochemistry International. 113, s. 46-55

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3-Hydroxysteroid Dehydrogenases
Nervous System
Neurons
Hormones
Enzymes
92 Downloads (Pure)

Orthologous proteins of experimental de- and remyelination are differentially regulated in the CSF proteome of multiple sclerosis subtypes

Martin, N. A., Nawrocki, A., Molnar, V., Elkjaer, M. L., Thygesen, E. K., Palkovits, M., Acs, P., Sejbaek, T., Nielsen, H. H., Hegedus, Z., Sellebjerg, F., Molnar, T., Barbosa, E. G. V., Alcaraz, N., Gallyas, F., Svenningsen, A. F., Baumbach, J., Lassmann, H., Larsen, M. R. & Illes, Z., 2018, I : PLOS ONE. 13, 8, s. 1-26 e0202530.

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sclerosis
Demyelinating Diseases
Proteome
proteome
beta 2-Microglobulin
116 Downloads (Pure)

Psychiatry in a Dish: Stem Cells and Brain Organoids Modeling Autism Spectrum Disorders

Ilieva, M., Fex Svenningsen, Å., Thorsen, M. & Michel, T. M., 1. apr. 2018, I : Biological Psychiatry. 83, 7, s. 558-568

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Organoids
Neurobiology
Tissue Engineering
Cell Communication
Cognition
2017

Autism in a "Dish": Cerebral organoids modeling neurodevelopmental pathology

Ilieva, M., Kamand, M., Fex Svenningsen, Å. & Michel, T. M., 3. apr. 2017.

Publikation: Konferencebidrag uden forlag/tidsskriftPosterForskningpeer review

115 Downloads (Pure)

Macrophage migration inhibitory factor (MIF) modulates trophic signaling through interaction with serine protease HTRA1

Fex Svenningsen, Å., Loering, S., Sørensen, A. L., Uyen Buu Huynh, H., Hjæresen, S., Martin, N. A., Møller, J. B., Elkjær, M. L., Holmskov, U., Illés, Z., Andersson, M., Nielsen, S. B. & Benedikz, E., 2017, I : Cellular and Molecular Life Sciences. 74, 24, s. 4561–4572

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Macrophage Migration-Inhibitory Factors
Central Nervous System Diseases
Neurodegenerative Diseases
Peptide Hydrolases
Central Nervous System

Neurodevelopment in a Dish: Elucidates the Miechanisms of Autism SDpectrum Disorders

Ilieva, M., Kolev, K. V., Forsberg, S. L., Fex Svenningsen, Å. & Michel, T. M., 2. apr. 2017.

Publikation: Konferencebidrag uden forlag/tidsskriftPosterForskningpeer review

"Neurodevelopment in a dish" Elucidates the mechanisms of autism spectrum disorders

Ilieva, M., Kamand, M., Kolev, K. V., Forsberg, S. L., Fex Svenningsen, Å. & Michel, T. M., 2017.

Publikation: Konferencebidrag uden forlag/tidsskriftPosterForskning

92 Downloads (Pure)

Opioid precursor protein isoform is targeted to the cell nuclei in the human brain

Kononenko, O., Bazov, I., Watanabe, H., Gerashchenko, G., Dyachok, O., Verbeek, D. S., Alkass, K., Druid, H., Andersson, M., Mulder, J., Fex Svenningsen, Å., Rajkowska, G., Krishtal, O., Yakovleva, T. & Bakalkin, G., 2017, I : B B A - General Subjects. 1861, 2, s. 246–255

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Opioid Analgesics
Brain
Protein Isoforms
Cells
Neuropeptides
2016
129 Downloads (Pure)

Genetic ablation of soluble TNF does not affect lesion size and functional recovery after moderate spinal cord injury in mice

Ellman, D. G., Degn, M., Lund, M. C., Clausen, B. H., Novrup, H. G., Flæng, S. B., Jørgensen, L. H., Suntharalingam, L., Fex Svenningsen, Å., Brambilla, R. & Lambertsen, K. L., 2016, I : Mediators of Inflammation. 2016, 2684098.

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Patient's derived induced pluripotent stem cells and 3D brain organoids for modeling Autism spectrum disorder

Ilieva, M., Bitsch, T. B., Fex Svenningsen, Å., Benedikz, E. & Michel, T. M., 2016.

Publikation: Konferencebidrag uden forlag/tidsskriftPosterForskningpeer review

Patients derived pluripotent stem cells and 3D organoids for modelling Autism spectrum disorders

Ilieva, M., Bitsch, T. B., Fex Svenningsen, Å., Benedikz, E. & Michel, T. M., 2016.

Publikation: Konferencebidrag uden forlag/tidsskriftPosterForskningpeer review

2015

GABA and its B-receptor are present at the node of Ranvier in a small population of sensory fibers, implicating a role in myelination

Corell, M., Wicher, G., Radomska, K. J., Daglikoca, E. D., Godskesen, R. E., Fredriksson, R., Benedikz, E., Magnaghi, V. & Fex Svenningsen, Å., 1. feb. 2015, I : Journal of Neuroscience Research. 3, 93, s. 285-295 11 s.

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Ranvier's Nodes
GABA-B Receptors
Neuroglia
Schwann Cells
Peripheral Nervous System

The Rat Homolog of the Schizophrenia Susceptibility Gene ZNF804A Is Highly Expressed during Brain Development, Particularly in Growth Cones

Hinna, K. H., Rich, K., Fex Svenningsen, Å. & Benedikz, E., 2015, I : P L o S One. 10, 7, 13 s., e0132456.

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Growth Cones
cones (retina)
Cones
Rats
Brain
2014
55 Downloads (Pure)

Kvalitetsutvärdering av biomedicin och närliggande huvudområden

Leffler, H., Fex Svenningsen, Å., Emgård, M., Krengel, U., Lundgren, E., Rehn, M., Eriksson, M. & Halle, T., 6. maj 2014, 151 s. Universitetskanslerämbetet, Stockholm, Sverige.

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Oxaliplatin-induced neuropathy in colorectal cancer: Many questions with few answers

Zedan, A., Hansen, T. F., Fex Svenningsen, Å. & Vilholm, O. J., jun. 2014, I : Clinical Colorectal Cancer. 13, 2, s. 73-80 8 s.

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oxaliplatin
Colorectal Neoplasms
Pharmacogenetics
Platinum
2013
333 Downloads (Pure)

Repair of the Peripheral Nerve—Remyelination that Works

Fex Svenningsen, Å. & Dahlin, L., 2013, I : Brain Sciences. 3, 3, s. 1182-1197

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Fil
Peripheral Nervous System
Wallerian Degeneration
Schwann Cells
Wounds and Injuries
Research
2011

Effects on DHEA levels by estrogen in rat astrocytes and CNS co-cultures via the regulation of CYP7B1-mediated metabolism.

Fex Svenningsen, Å., Wicher, G., Lundqvist, J., Pettersson, H. & Norlin, M., 2011, I : Neurochemistry International. 58, s. 620-624 5 s.

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Coculture Techniques
Estrogens
Hydroxylation
Neuroprotective Agents
Metabolic Networks and Pathways

MALDI mass spectrometry based molecular phenotyping of CNS glial cells for prediction in mammalian brain tissue

Hanrieder, J., Wicher, G., Bergquist, J., Andersson, M. & Fex Svenningsen, Å., 7. maj 2011, I : Analytical and Bioanalytical Chemistry. 401, 1, s. 135-147

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Neurology
Mass spectrometry
Brain
Tissue
Proteins
2010

A Low Ethanol Dose Affects all Types of Cells in Mixed Long-Term Embryonic Cultures of the Cerebellum

Pickering, C., Wicher, G., Rosendahl, S., Schiöth, H. B. & Fex Svenningsen, Å., 14. jan. 2010, I : Basic & Clinical Pharmacology & Toxicology. 106, 6, s. 472-478 7 s.

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Ethanol
Nestin
Cells
Neurons
Wine

In Vitro Neurotoxicity of PBDE-99: Immediate and Concentration-Dependent Effects on Protein Expression in Cerebral Cortex Cells

Alm, H., Scholz, B., Kultima, K., Nilsson, A., Andrén, P. E., Savitski, M. M., Bergman, A., Stigson, M., Svenningsen, Å. F. & Dencker, L., 2010, I : Journal of Proteome Research. 9, 3, s. 1226-1235

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Halogenated Diphenyl Ethers
Two-Dimensional Difference Gel Electrophoresis
Proteins
Flame Retardants
Cytoskeletal Proteins

MDMA (Ecstasy) Decreases the Number of Neurons and Stem Cells in Embryonic Cortical Cultures

Kindlundh-Högberg, A. M. S., Pickering, C., Wicher, G., Hobér, D., Schiöth, H. B. & Svenningsen, Å. F., 2010, I : Cellular & Molecular Neurobiology. 30, 1, s. 13-21

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Neurons
Messenger RNA
Nestin
Dopamine Receptors
Neurotransmitter Agents

Optimization of chemically defined cell culture media - Replacing fetal bovine serum in mammalian in vitro methods

van der Valk, J., Brunner, D., De Smet, K., Fex Svenningsen, Å., Honegger, P., Knudsen, L. E., Lindl, T., Noraberg, J., Price, A., Scarino, M. L. & Gstraunthaler, G., 31. mar. 2010, I : Toxicology in Vitro. 24, 4, s. 1053-1063 11 s.

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Serum-Free Culture Media
Cell culture
Culture Media
Animals
Serum

Spatiotemporal distribution and function of N-cadherin in postnatal Schwann cells: A matter of adhesion?

Corell, M., Wicher, G., Limbach, C., Kilimann, M. W., Colman, D. R. & Fex Svenningsen, Å., 2010, I : Journal of Neuroscience Research. 88, 11, s. 2338-49 12 s.

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Schwann Cells
Neuroglia
Peripheral Nervous System
Spinal Ganglia
Myenteric Plexus
2008

Environmental cues from CNS, PNS, and ENS cells regulate CNS progenitor differentiation

Brännvall, K., Corell, M., Forsberg-Nilsson, K. & Svenningsen, Å. F., 2008, I : NeuroReport. 19, 13, s. 1283-9 6 s.

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Cues
Central Nervous System
Conditioned Culture Medium
Cell Differentiation
Neural Crest

Exposure to brominated flame retardant PBDE-99 affects cytoskeletal protein expression in the neonatal mouse cerebral cortex

Alm, H., Kultima, K., Scholz, B., Nilsson, A., Andrén, P. E., Svenningsen, Å. F., Dencker, L. & Stigson, M., 2008, I : NeuroToxicology. 29, 4, s. 628-37 9 s.

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Halogenated Diphenyl Ethers
Flame Retardants
Cytoskeletal Proteins
Two-Dimensional Difference Gel Electrophoresis
Proteins

Extracellular clusterin promotes neuronal network complexity in vitro

Wicher, G., Velsecchi, I., Charnay, Y., Aldskogius, H. & Svenningsen, Å. F., 2008, I : NeuroReport. 19, 15, s. 1487-91 4 s.

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Clusterin
Physiological Phenomena
In Vitro Techniques
Cell Survival
Lipids

Microfluidic high viability neural cell separation using viscoelastically tuned hydrodynamic spreading

Wu, Z., Hjort, K., Wicher, G. & Svenningsen, Å. F., 2008, I : Biomedical Microdevices. 10, 5, s. 631-8 7 s.

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Hydrodynamics
Microfluidics
Microspheres
Latexes
Fluorescent Dyes
2006

Low density lipoprotein receptor-related protein-2/megalin is expressed in oligodendrocytes in the mouse spinal cord white matter

Wicher, G., Larsson, M., Svenningsen, Å. F., Gyllencreutz, E., Rask, L. & Aldskogius, H., 2006, I : Journal of Neuroscience Research. 83, 5, s. 864-73 9 s.

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Oligodendroglia
Lipoprotein Receptors
Presenilin-1
Choroid Plexus
White Matter
2005

Glial membranes at the node of Ranvier prevent neurite outgrowth

Huang, J. K., Phillips, G. R., Roth, A. D., Pedraza, L., Shan, W., Belkaid, W., Mi, S., Svenningsen, Å. F., Florens, L., Yates, J. R. & Colman, D. R., 2005, I : Science. 310, 5755, s. 1813-7 4 s.

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Ranvier's Nodes
Neuroglia
Central Nervous System
Membranes
Oligodendroglia
2004

Satellite cells of dorsal root ganglia are multipotential glial precursors

Svenningsen, Å. F., Colman, D. R. & Pedraza, L., 2004, I : Neuron Glia Biology. 1, 1, s. 85-93 8 s.

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The minimal essential unit for cadherin-mediated intercellular adhesion comprises extracellular domains 1 and 2

Shan, W., Yagita, Y., Wang, Z., Koch, A., Svenningsen, Å. F., Gruzglin, E., Pedraza, L. & Colman, D. R., 2004, I : Journal of Biological Chemistry. 279, 53, s. 55914-23 9 s.

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Cadherins
Adhesion
Cell adhesion
Cell Adhesion
Adhesives

The modular xylanase Xyn10A from Rhodothermus marinus is cell-attached, and its C-terminal domain has several putative homologues among cell-attached proteins within the phylum Bacteroidetes

Karlsson, E. N., Hachem, M. A., Ramchuran, S., Costa, H., Holst, O., Fex Svenningsen, Å. & Hreggvidsson, G. O., 15. dec. 2004, I : F E M S Microbiology Letters. 241, 2, s. 233-42 10 s.

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Rhodothermus
Proteins
Cytophaga
Protein C
Computational Biology
2003

Rapid method for culturing embryonic neuron-glial cell cocultures

Svenningsen, Å. F., Shan, W-S., Colman, D. R. & Pedraza, L., 2003, I : Journal of Neuroscience Research. 72, 5, s. 565-73 8 s.

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Coculture Techniques
Neuroglia
Neurons
Spinal Ganglia
Peripheral Nervous System

Vasoactive intestinal peptide and nitric oxide promote survival of adult rat myenteric neurons in culture

Sandgren, K., Lin, Z., Svenningsen, Å. F. & Ekblad, E., 2003, I : Journal of Neuroscience Research. 72, 5, s. 595-602 7 s.

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Vasoactive Intestinal Peptide
Nitric Oxide
Neurons
Nitric Oxide Synthase
Nitric Oxide Donors
1999

Estrogen and progesterone stimulate Schwann cell proliferation in a sex- and age-dependent manner

Svenningsen, Å. F. & Kanje, M., 1999, I : Journal of Neuroscience Research. 57, 1, s. 124-30 6 s.

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Schwann Cells
Estrogens
Cell Proliferation
Progesterone Receptors
1998

Regulation of Schwann cell proliferation in cultured segments of the adult rat sciatic nerve

Svenningsen, Å. F. & Kanje, M., 1998, I : Journal of Neuroscience Research. 52, 5, s. 530-7 7 s.

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Schwann Cells
Cell Proliferation
Egtazic Acid
Ionophores
Calcimycin
1997

The insulin-like growth factors I and II stimulate proliferation of different types of Schwann cells

Sondell, M., Svenningsen, Å. F. & Kanje, M., 1997, I : NeuroReport. 8, 13, s. 2871-6 5 s.

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Insulin-Like Growth Factor II
Schwann Cells
Insulin-Like Growth Factor I
Insulin
Myelinated Nerve Fibers
1996
Insulin-Like Growth Factor II
Insulin-Like Growth Factor I
Insulin
Schwann Cells
Peripheral Nerves
1994

Insulin and IGF-II, but not IGF-I, stimulate the in vitro regeneration of adult frog sciatic sensory axons

Edbladh, M., Svenningsen, Å. F., Ekström, P. A. & Edström, A., 1994, I : Brain Research. 641, 1, s. 76-82 6 s.

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Insulin-Like Growth Factor II
Insulin-Like Growth Factor I
Insulin
Cell Proliferation
Peripheral Nerves

Insulin-like growth factor II (IGF-II) stimulates regeneration and proliferation in the rat sciatic nerve

Svenningsen, Å. F., Kanje, M. & Sjøberg, J., 1994, I : Neuroscience Research Communications. 15, s. 111-118 5 s.

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1993

Effects of insulin and insulin-like growth factor-2 on the in vitro regeneration of the frog sciatic nerve

Ekström, P. A., Edbladh, M. & Svenningsen, Å. F., 1993, I : Annals of the New York Academy of Sciences. 692, s. 291-293

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