Personlig profil
Forskningsinteresser
I am a medical doctor and microbiologist and my previous and ongoing research is based on a desire to explain the pathogenesis and causality of recurrent urinary tract infections. The ultimate aim of my work is to contribute to better diagnostics of urinary tract infections and to develope novel antimicrobial interventions against this disease. I have clinical experience from the department of urology, Vejle Hospital and the department of Clinical Microbiology, Odense University Hospital. I have studied E. coli biofilm formation at NASA Kennedy Space Center, Florida, during a research stay in 2015.
Most of my research involves the use of a porcine model of urinary tract infection. This model was developed as part of my PhD and is the only one of its kind in the world. The model is used in multiple projects with different purposes:
- Uropathogenic Escherichia coli pathogenesis and biofilm-formation
- Vaccine development and pre-clinical test
- Catheter-associated urothelial micro-trauma and risk of infection
- Evaluation of Cranberry products for prevention of urinary tract infection
- Novel antibiotics for treatment of Enterococcol urinary tract infection
- Ongoing optimization and expansion of the porcine model
My position in the Clinical Biofilm Group enables research collaborations with different research groups and medical companies, where my role is study design, project management, supervision and conducting experimental work in the pig model.
Published peer-review articles:
Total: 18, hereof 12 as first author and 6 as corresponding author.
Emneord
- Antibiotica
- Bakterier
- Infektion
- Urininkontinens
Fingeraftryk
- 1 Lignende profiler
Samarbejde og topforskningsområder i de sidste fem år
Publikationer
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Hyperosmolarity of mouse urine confounds research in urinary tract infection
Stærk, K., Hjelmager, J. S., Grønnemose, R. B., Bach, M. L., Pettersen, J. S. & Andersen, T. E., 2026, (E-pub ahead of print) I: Lab Animal.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
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Response to: Bridging research and patient experience in chronic urinary tract infection
Andersen, K., Hjelmager, J. S., Andersen, T. E. & Stærk, K., maj 2026, I: BJU International. 137, 5, s. 924 1 s.Publikation: Bidrag til tidsskrift › Kommentar/debat › Forskning › peer review
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Effect of Bladder Catheterization On Bacterial Interference With Asymptomatic Escherichia coli Strain 83972 in an Experimental Porcine Model of Urinary Tract Infection
Stærk, K., Andersen, K., Hjelmager, J. S., Jensen, L. K., Jørgensen, B. M., Møller-Jensen, J., Lund, L. & Andersen, T. E., 20. feb. 2025, I: The Journal of Infectious Diseases. 231, 2, s. e355-e363Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
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Linker and Head-Group Exploration of Anti-MRSA Triaromatic Pleuromutilins
Heidtmann, C. V., Fisker, C. D., Løgstrup, S., Eriksen, P. G., Storm, L. H., Stærk, K., Moesgaard, L., Pedersen, M., Madsen, M. J., Yusuf, A., Urup, K., Højgaard, I. S., Ramesh, J., Pihlsbech, R. H., Sørensen, C. B., Rønn, T. L., Larsen, A. B., Caspersen, L. R., Møller, M. Æ. & Sixhøj, C. R. & 5 flere, , 2025, I: Journal of Medicinal Chemistry. 68, 9, s. 9479–9500Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
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Macroscopic renal lesions and corresponding MRI findings following elevated intrarenal pressure with E. coli-inoculated saline in a porcine model
Lykkegaard, E. G., Hansen, E. S. S., Ringgaard, S., Bertelsen, L. B., Nørregaard, R., Jensen, L. K., Lildal, S. K., Mohanakumar, S., Graumann, O., Stærk, K., Laustsen, C., Jung, H., Blirup-Plum, S. A. & Kørup Trosborg, K., nov. 2025, I: European Urology Open Science. 81, Suppl. 2, s. S21-S22 2 s., MP18.Publikation: Bidrag til tidsskrift › Konferenceabstrakt i tidsskrift › Forskning › peer review
Åben adgangFil5 Downloads (Pure)
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ESCMID Global 2024
Stærk, K. (Deltager)
27. apr. 2024 → 30. apr. 2024Aktivitet: Deltagelse i faglig begivenhed › Organisering af eller deltagelse i konference
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Establishing a pig model for preclinical evaluation of vaccines against urinary tract infection
Stærk, K. (Oplægsholder), Boysen, A. (Forfatter), Andersen, A. Z. (Forfatter), Throsing, M. (Forfatter), Hjelmager, J. S. (Forfatter), Palarasah, Y. (Forfatter) & Andersen, T. E. (Forfatter)
18. apr. 2023Aktivitet: Foredrag og mundtlige bidrag › Konferenceoplæg
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33rd ECCMID, the European Congress of Clinical Microbiology and Infectious Diseases
Stærk, K. (Deltager)
15. apr. 2023 → 18. apr. 2023Aktivitet: Deltagelse i faglig begivenhed › Organisering af eller deltagelse i konference
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Genome-wide analysis of uropathogenic Escherichia coli fitness factors during growth in human urine and urinary tract infection in a pig model
Vanessa, G. (Oplægsholder), Stærk, K. (Medforfatter), Alobaidallaha, A. (Medforfatter), Saleh, M. (Medforfatter), Grønnemose, R. B. (Medforfatter), Guerra, P. R. (Medforfatter), Andersen, T. E. (Medforfatter), E. Olsen, J. (Medforfatter) & Herrero-Fresno, A. (Medforfatter)
23. sep. 2022Aktivitet: Foredrag og mundtlige bidrag › Konferenceoplæg
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