Publikationer 1973 2019

2019
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A Birth Cohort Study on the Genetic Modification of the Association of Prenatal Methylmercury With Child Cognitive Development

Julvez, J., Smith, G. D., Ring, S. M. & Grandjean, P., 1. okt. 2019, I : American Journal of Epidemiology. 188, 10, s. 1784-1793

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Cohort Studies
Mercury
Progesterone Receptors
Single Nucleotide Polymorphism
Alleles

Anogenital distance in children born of mothers with polycystic ovary syndrome: the Odense Child Cohort

Glintborg, D., Jensen, R. C., Schmedes, A. V., Brandslund, I., Kyhl, H. B., Nielsen, T. K. & Andersen, M. S., 2. okt. 2019, I : Human reproduction (Oxford, England). 34, 10, s. 2061-2070

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Polycystic Ovary Syndrome
Mothers
Penis
Denmark
Research

Anogenital distance is associated with semen quality but not reproductive hormones in 1106 young men from the general population

Priskorn, L., Bang, A. K., Nordkap, L., Krause, M., Mendiola, J., Jensen, T. K., Juul, A., Skakkebaek, N. E., Swan, S. H. & Jørgensen, N., 1. jan. 2019, I : Human reproduction (Oxford, England). 34, 1, s. 12-24

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Hormones
Population
Odds Ratio
Semen
Scrotum

A phase I study of the PARP inhibitor niraparib in combination with bevacizumab in platinum-sensitive epithelial ovarian cancer: NSGO AVANOVA1/ENGOT-OV24

Mirza, M. R., Bergmann, T. K., Mau-Sørensen, M., Christensen, R. D., Åvall-Lundqvist, E., Birrer, M. J., Jørgensen, M., Roed, H., Malander, S., Nielsen, F., Lassen, U., Brøsen, K., Bjørge, L. & Mäenpää, J., okt. 2019, I : Cancer Chemotherapy and Pharmacology. 84, 4, s. 791-798

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Platinum
Angiogenesis Inhibitors
Germ-Line Mutation
Ovarian Neoplasms
Disease-Free Survival

Associations of exposure to perfluoroalkyl substances with thyroid hormone concentrations and birth size

Xiao, C., Grandjean, P., Valvi, D., Nielsen, F., Jensen, T. K., Weihe, P. & Oulhote, Y., 29. okt. 2019, I : The Journal of clinical endocrinology and metabolism.

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perfluorooctanoic acid
Thyrotropin
Thyroid Hormones
Mothers
Linear regression
22 Downloads (Pure)

A strategy to validate a selection of human effect biomarkers using adverse outcome pathways: Proof of concept for phthalates and reproductive effects

Baken, K. A., Lambrechts, N., Remy, S., Mustieles, V., Rodríguez-Carrillo, A., Neophytou, C. M., Olea, N. & Schoeters, G., 2019, I : Environmental Research. 175, s. 235-256

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phthalate
Biomarkers
biomarker
Peroxisome Proliferator-Activated Receptors
Health

Bone mineral density is preserved in men with idiopathic infertility

Antonio, L., Priskorn, L., Nordkap, L., Bang, A. K., Jensen, T. K., Skakkebæk, N. E., Petersen, J. H., Vanderschueren, D. & Jørgensen, N., 2019, I : Andrology.

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Bone Density
Infertility
Femur Neck
Photon Absorptiometry
Semen

Development priority

Grandjean, P., Prins, G. S. & Weihe, P., aug. 2019, I : Basic & Clinical Pharmacology & Toxicology. 125, S3, s. 3-4

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Early life exposures to perfluoroalkyl substances in relation to adipokine hormone levels at birth and during childhood

Shelly, C., Grandjean, P., Oulhote, Y., Plomgaard, P., Frikke-Schmidt, R., Nielsen, F., Zmirou-Navier, D., Weihe, P. & Valvi, D., 1. nov. 2019, I : The Journal of clinical endocrinology and metabolism. 104, 11, s. 5338-5348

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Adipokines
Resistin
Hormones
Adiponectin
Leptin

Endocrine disrupters, semen quality and anogenital distance

Jensen, T. K., aug. 2019, I : Current Opinion in Endocrine and Metabolic Research. 7, s. 34-42

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Maternal Exposure
Chlorinated Hydrocarbons
Endocrine Disruptors
Reproductive Health
Meta-Analysis
37 Downloads (Pure)

Environmental chemical exposures among Greenlandic children in relation to diet and residence

Timmermann, C. A. G., Pedersen, H. S., Budtz-Jørgensen, E., Bjerregaard, P., Oulhote, Y., Weihe, P., Nielsen, F. & Grandjean, P., dec. 2019, I : International Journal of Circumpolar Health. 78, 1, 11 s., 1642090.

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Environmental Exposure
Diet
Proxy
Mercury
Linear Models

Fish Consumption During Pregnancy

Grandjean, P., Lederman, S. A. & Silbergeld, E. K., 1. mar. 2019, I : JAMA Pediatrics. 173, 3

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Gender differences in cognitive performance and health status in the Faroese Septuagenarians cohort

Petersen, M. S., Debes, F., Grandjean, P. & Weihe, P., feb. 2019, I : European Journal of Public Health. 29, 1, s. 79–81

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Joint Diseases
Myalgia
Cross-Sectional Studies
Health
Surveys and Questionnaires

Hair cortisol in newly diagnosed bipolar disorder and unaffected first-degree relatives

Coello, K., Munkholm, K., Nielsen, F., Vinberg, M. & Kessing, L. V., jan. 2019, I : Psychoneuroendocrinology. 99, s. 183-190

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Hair
Wounds and Injuries

Improving and Expanding Estimates of the Global Burden of Disease Due to Environmental Health Risk Factors

Shaffer, R. M., Sellers, S. P., Baker, M. G., de Buen Kalman, R., Frostad, J., Suter, M. K., Anenberg, S. C., Balbus, J., Basu, N., Bellinger, D. C., Birnbaum, L., Brauer, M., Cohen, A., Ebi, K. L., Fuller, R., Grandjean, P., Hess, J. J., Kogevinas, M., Kumar, P., Landrigan, P. J. & 7 flere, Lanphear, B., London, S. J., Rooney, A. A., Stanaway, J. D., Trasande, L., Walker, K. & Hu, H., okt. 2019, I : Environmental Health Perspectives. 127, 10, s. 105001

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Environmental Health
Air Pollution
Health
Endocrine Disruptors
Premature Mortality

Mothers and children are related, even in exposure to chemicals present in common consumer products

Koppen, G., Govarts, E., Vanermen, G., Voorspoels, S., Govindan, M., Dewolf, M. C., Den Hond, E., Biot, P., Casteleyn, L., Kolossa-Gehring, M., Schwedler, G., Angerer, J., Koch, H. M., Schindler, B. K., Castaño, A., López, M. E., Sepai, O., Exley, K., Bloemen, L., Knudsen, L. E. & 4 flere, Joas, R., Joas, A., Schoeters, G. & Covaci, A., aug. 2019, I : Environmental Research. 175, s. 297-307

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Consumer products
phthalate
Triclosan
Mothers
Dibutyl Phthalate

Perfluorinated substances, risk factors for multiple sclerosis and cellular immune activation

Ammitzbøll, C., Börnsen, L., Petersen, E. R., Oturai, A. B., Søndergaard, H. B., Grandjean, P. & Sellebjerg, F., 15. maj 2019, I : Journal of Neuroimmunology. 330, s. 90-95

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Smoking
perfluorooctane sulfonic acid

Perfluoroalkyl substances and changes in bone mineral density: A prospective analysis in the POUNDS-LOST study

Hu, Y., Liu, G., Rood, J., Liang, L., Bray, G. A., de Jonge, L., Coull, B., Furtado, J. D., Qi, L., Grandjean, P. & Sun, Q., 2019, I : Environmental Research. 179, 7 s., 108775.

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Bone Density
Minerals
bone
Bone
Hip
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Physico-chemical properties and gestational diabetes predict transplacental transfer and partitioning of perfluoroalkyl substances

Eryasa, B., Grandjean, P., Nielsen, F., Valvi, D., Zmirou-Navier, D., Sunderland, E., Weihe, P. & Oulhote, Y., sep. 2019, I : Environment International. 130, s. 104874

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diabetes
chemical property
partitioning
blood
serum
Adiposity
Adipose Tissue
Cohort Studies
Mothers
Linear Models

Prenatal bisphenol A exposure is associated with language development but not with ADHD-related behavior in toddlers from the Odense Child Cohort

Jensen, T. K., Mustieles, V., Bleses, D., Frederiksen, H., Trecca, F., Schoeters, G., Andersen, H. R., Grandjean, P., Kyhl, H. B., Juul, A., Bilenberg, N. & Andersson, A. M., 1. mar. 2019, I : Environmental Research. 170, s. 398-405

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Mothers
urine
Urine
breastfeeding
fasting
41 Downloads (Pure)

Prevalence of prediabetes and type 2 diabetes in two non-random populations aged 44–77 years in the Faroe Islands

Veyhe, A. S., Andreassen, J., Halling, J., Grandjean, P., Skaalum Petersen, M. & Weihe, P., jun. 2019, I : Journal of Clinical and Translational Endocrinology. 16, 8 s., 100187.

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Prediabetic State
Denmark
Type 2 Diabetes Mellitus
Population
Fasting

Response to Juberg et al

Mie, A., Rudén, C. & Grandjean, P., 2019, I : Environmental Health. 18, 3 s., 29.

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Tap water contributions to plasma concentrations of poly- and perfluoroalkyl substances (PFAS) in a nationwide prospective cohort of U.S. women

Hu, X. C., Tokranov, A. K., Liddie, J., Zhang, X., Grandjean, P., Hart, J. E., Laden, F., Sun, Q., Yeung, L. W. Y. & Sunderland, E. M., jun. 2019, I : Environmental Health Perspectives. 127, 6, 11 s., 067006.

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perfluorooctanoic acid
Nurses
United States Environmental Protection Agency
Fluorine
Water Supply
Registries
Twin Studies
Denmark
Polycystic Ovary Syndrome
Third Pregnancy Trimester
Mothers
Cortisone
Fasting
9 Downloads (Pure)

Time scales of developmental toxicity impacting on research and needs for intervention

Grandjean, P., Abdennebi-Najar, L., Barouki, R., Cranor, C. F., Etzel, R. A., Gee, D., Heindel, J. J., Hougaard, K. S., Hunt, P., Nawrot, T. S., Prins, G. S., Ritz, B., Soffritti, M., Sunyer, J. & Weihe, P., aug. 2019, I : Basic & Clinical Pharmacology & Toxicology. 125, Suppl. 3, s. 70-80

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Toxicity
Research
Health
Computational chemistry
Epidemiology
2018

Accelerated functional losses in ageing congenital Minamata disease patients

Yorifuji, T., Takaoka, S. & Grandjean, P., 10. aug. 2018, I : Neurotoxicology and Teratology. 69, s. 49-53

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Nervous System Mercury Poisoning
Aging of materials
Cognition
Cerebral Palsy
Poisoning

Anogenital distance as a phenotypic signature through infancy

Priskorn, L., Petersen, J. H., Jørgensen, N., Kyhl, H. B., Andersen, M. S., Main, K. M., Andersson, A-M., Skakkebaek, N. E. & Jensen, T. K., mar. 2018, I : Pediatric Research. 83, 3, s. 573–579

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Clitoris
Scrotum
Penis
Equidae
Pediatrics
87 Downloads (Pure)

A novel inverse association between cord 25-hydroxyvitamin D and leg length in boys up to three years: An Odense Child Cohort study

Christensen, M. E., Beck-Nielsen, S. S., Dalgård, C., Larsen, S. D., Lykkedegn, S., Kyhl, H. B., Husby, S. & Christesen, H. T., 1. jun. 2018, I : PLOS ONE. 13, 6, 17 s., e0198724.

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cohort studies
Leg
legs
Cohort Studies
rickets
56 Downloads (Pure)

Application of benchmark analysis for mixed contaminant exposures: Mutual adjustment of perfluoroalkylate substances associated with immunotoxicity

Budtz-Jørgensen, E. & Grandjean, P., 2018, I : PLOS ONE. 13, 10, 14 s., e0205388.

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immunotoxicity
Benchmarking
Impurities
Antibodies
dosage
88 Downloads (Pure)
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Maternal Exposure
Pyrethrins
2,4-Dichlorophenoxyacetic Acid
Organophosphates
Herbicides
48 Downloads (Pure)

A systems biology approach to predictive developmental neurotoxicity of a larvicide used in the prevention of Zika virus transmission

Audouze, K., Taboureau, O. & Grandjean, P., sep. 2018, I : Toxicology and Applied Pharmacology. 354, s. 56-63

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pyriproxyfen
Systems Biology
Viruses
Microcephaly
Toxicity

Average sperm count remains unchanged despite reduction in maternal smoking: results from a large cross-sectional study with annual investigations over 21 years

Priskorn, L., Nordkap, L., Bang, A. K., Krause, M., Holmboe, S. A., Egeberg Palme, D. L., Winge, S. B., Mørup, N., Carlsen, E., Joensen, U. N., Blomberg Jensen, M., Main, K. M., Juul, A., Skakkebaek, N. E., Jensen, T. K. & Jørgensen, N., 1. jun. 2018, I : Human Reproduction. 33, 6, s. 998-1008

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Cross-Sectional Studies
Smoking
Mothers
Maternal Exposure
Semen
58 Downloads (Pure)

Blood pressure in 3-year-old girls associates inversely with umbilical cord serum 25-hydroxyvitamin D: an Odense Child Cohort study

Larsen, S. D., Dalgård, C., Christensen, M. E., Lykkedegn, S., Andersen, L. B., Andersen, M., Glintborg, D. & Christesen, H. T., 1. okt. 2018, I : Endocrine Connections. 7, 12, s. 1236–1244

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Umbilical Cord
Cohort Studies
Serum
25-Hydroxyvitamin D 2
Mothers
83 Downloads (Pure)

Can profiles of poly- and Perfluoroalkyl substances (PFASs) in human serum provide information on major exposure sources?

Hu, X. C., Dassuncao, C., Zhang, X., Grandjean, P., Weihe, P., Webster, G. M., Nielsen, F. & Sunderland, E. M., 1. feb. 2018, I : Environmental Health: A Global Access Science Source. 17, 15 s., 11.

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Serum
Seafood
perfluorooctanoic acid
Population
Health
89 Downloads (Pure)

Cohort Profile: Pregnancy And Childhood Epigenetics (PACE) Consortium

Felix, J. F., Joubert, B. R., Baccarelli, A. A., Sharp, G. C., Almqvist, C., Annesi-Maesano, I., Arshad, H., Baïz, N., Bakermans-Kranenburg, M. J., Bakulski, K. M., Binder, E. B., Bouchard, L., Breton, C. V., Brunekreef, B., Brunst, K. J., Burchard, E. G., Bustamante, M., Chatzi, L., Cheng Munthe-Kaas, M., Corpeleijn, E. & 104 flere, Czamara, D., Dabelea, D., Davey Smith, G., De Boever, P., Duijts, L., Dwyer, T., Eng, C., Eskenazi, B., Everson, T. M., Falahi, F., Fallin, M. D., Farchi, S., Fernandez, M. F., Gao, L., Gaunt, T. R., Ghantous, A., Gillman, M. W., Gonseth, S., Grote, V., Gruzieva, O., Håberg, S. E., Herceg, Z., Hivert, M-F., Holland, N., Holloway, J. W., Hoyo, C., Hu, D., Huang, R-C., Huen, K., Järvelin, M-R., Jima, D. D., Just, A. C., Karagas, M. R., Karlsson, R., Karmaus, W., Kechris, K. J., Kere, J., Kogevinas, M., Koletzko, B., Koppelman, G. H., Küpers, L. K., Ladd-Acosta, C., Lahti, J., Lambrechts, N., Langie, S. A. S., Lie, R. T., Liu, A. H., Magnus, M. C., Magnus, P., Maguire, R. L., Marsit, C. J., McArdle, W., Melén, E., Melton, P., Murphy, S. K., Nawrot, T. S., Nisticò, L., Nohr, E. A., Nordlund, B., Nystad, W., Oh, S. S., Oken, E., Page, C. M., Perron, P., Pershagen, G., Pizzi, C., Plusquin, M., Raikkonen, K., Reese, S. E., Reischl, E., Richiardi, L., Ring, S., Roy, R. P., Rzehak, P., Schoeters, G., Schwartz, D. A., Sebert, S., Snieder, H., Sørensen, T. I. A., Starling, A. P., Sunyer, J., Taylor, J. A., Tiemeier, H., Ullemar, V., Vafeiadi, M., Van Ijzendoorn, M. H., Vonk, J. M., Vriens, A., Vrijheid, M., Wang, P., Wiemels, J. L., Wilcox, A. J., Wright, R. J., Xu, C-J., Xu, Z., Yang, I. V., Yousefi, P., Zhang, H., Zhang, W., Zhao, S., Agha, G., Relton, C. L., Jaddoe, V. W. V. & London, S. J., 1. feb. 2018, I : International Journal of Epidemiology. 47, 1, s. 22–23u

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Consensus statement on the need for innovation, transition and implementation of developmental neurotoxicity (DNT) testing for regulatory purposes

Fritsche, E., Grandjean, P., Crofton, K. M., Aschner, M., Goldberg, A., Heinonen, T., Hessel, E. V. S., Hogberg, H. T., Bennekou, S. H., Lein, P. J., Leist, M., Mundy, W. R., Paparella, M., Piersma, A. H., Sachana, M., Schmuck, G., Solecki, R., Terron, A., Monnet-Tschudi, F., Wilks, M. F. & 3 flere, Witters, H., Zurich, M-G. & Bal-Price, A., sep. 2018, I : Toxicology and Applied Pharmacology. 354, s. 3-6

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Consensus
Innovation
Needs Assessment
Environmental Exposure
Testing
Cohort Studies
Serum
Gestational Age
Cranial Fontanelles
25-hydroxyvitamin D
73 Downloads (Pure)
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Environmental Health
Health
Publications
Immune System
Public Health
68 Downloads (Pure)

Dermal uptake and percutaneous penetration of organophosphate esters in a human skin ex vivo model

Frederiksen, M., Stapleton, H. M., Vorkamp, K., Webster, T. F., Jensen, N. M., Sørensen, J. A., Nielsen, F., Knudsen, L. E., Sørensen, L. S., Clausen, P. A. & Nielsen, J. B., apr. 2018, I : Chemosphere. 197, s. 185-192

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organophosphate
ester
skin
penetration
phosphate

Epigenetics as a mechanism linking developmental exposures to long-term toxicity

Barouki, R., Melén, E., Herceg, Z., Beckers, J., Chen, J., Karagas, M., Puga, A., Xia, Y., Chadwick, L., Yan, W., Audouze, K., Slama, R., Heindel, J., Grandjean, P., Kawamoto, T. & Nohara, K., maj 2018, I : Environment International. 114, s. 77-86 10 s.

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toxicity
health and disease
endocrine disruptor
methylation
smoking

Forskere og universiteter bløder, mens forlagene skummer fløden

Dorch, B. F. & Grandjean, P., 22. sep. 2018

Publikation: AndetUdgivelser på nettet - Net-publikationFormidling

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Gestational Diabetes Mellitus: Does One Size Fit All? A Challenge to Uniform Worldwide Diagnostic Thresholds

McIntyre, H. D., Jensen, D. M., Jensen, R. C., Kyhl, H. B., Jensen, T. K., Glintborg, D. & Andersen, M., jul. 2018, I : Diabetes Care. 41, 7, s. 1339-1342

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Gestational Diabetes
Fasting
Pregnancy Complications
Denmark
Cohort Studies
57 Downloads (Pure)

GLI2 promoter hypermethylation in saliva of children with a respiratory allergy

Langie, S. A. S., Moisse, M., Szarc Vel Szic, K., Van Der Plas, E., Koppen, G., De Prins, S., Louwies, T., Nelen, V., Van Camp, G., Lambrechts, D., Schoeters, G., Vanden Berghe, W. & De Boever, P., 11. apr. 2018, I : Clinical Epigenetics (Print). 10, 13 s., 50.

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Saliva
Hypersensitivity
DNA Methylation
Genetic Markers
Epigenomics

Health Status of Workers Exposed to Perfluorinated Alkylate Substances

Grandjean, P., okt. 2018, I : Journal of occupational and environmental medicine . 60, 10, s. e562 1 s.

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84 Downloads (Pure)

Ibuprofen alters human testicular physiology to produce a state of compensated hypogonadism

Kristensen, D. M., Desdoits-Lethimonier, C., Mackey, A. L., Dalgaard, M. D., De Masi, F., Munkbøl, C. H., Styrishave, B., Antignac, J-P., Le Bizec, B., Platel, C., Hay-Schmidt, A., Jensen, T. K., Lesné, L., Mazaud-Guittot, S., Kristiansen, K., Brunak, S., Kjaer, M., Juul, A. & Jégou, B., 23. jan. 2018, I : Proceedings of the National Academy of Sciences of the United States of America. 115, 4, s. E715-E724

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Hypogonadism
Ibuprofen
Luteinizing Hormone
Western World
Endocrine System

Identification of sex-specific DNA methylation changes driven by specific chemicals in cord blood in a Faroese birth cohort

Leung, Y-K., Ouyang, B., Niu, L., Xie, C., Ying, J., Medvedovic, M., Chen, A., Weihe, P., Valvi, D., Grandjean, P. & Ho, S-M., 4. mar. 2018, I : Epigenetics. 13, 3, s. 290-300

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Dichlorodiphenyl Dichloroethylene
DNA Methylation
Fetal Blood
Hexachlorobenzene
Chlorinated Hydrocarbons
56 Downloads (Pure)

Impact of particulate matter on mothers and babies in Antwerp (IPANEMA): a prospective cohort study on the impact of pollutants and particulate matter in pregnancy

Van den Eeden, L., Lambrechts, N., Verheyen, V., Berth, M., Schoeters, G. & Jacquemyn, Y., 2018, I : BMJ Open. 8, 3, 6 s., e020028.

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Particulate Matter
Cohort Studies
Mothers
Prospective Studies
Pregnant Women