Publikationer 1989 2019

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Tidsskriftartikel
2019

Adalimumab in the treatment of chronic pouchitis. A randomized double-blind, placebo-controlled trial

Kjær, M. D., Qvist, N., Nordgaard-Lassen, I., Christensen, L. A. & Kjeldsen, J., 10. feb. 2019, I : Scandinavian Journal of Gastroenterology. 54, 2, s. 188-193

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Pouchitis
Placebos
Adalimumab
Colonic Pouches
54 Downloads (Pure)

ADAPT: An algorithm incorporating PRO-C3 accurately identifies patients with NAFLD and advanced fibrosis

Daniels, S. J., Leeming, D. J., Eslam, M., Hashem, A. M., Nielsen, M. J., Krag, A., Karsdal, M. A., Grove, J. I., Guha, I. N., Kawaguchi, T., Torimura, T., McLeod, D., Akiba, J., Kaye, P., de Boer, B., Aithal, G. P., Adams, L. A. & George, J., mar. 2019, I : Hepatology (Baltimore, Md.). 69, 3, s. 1075-1086

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Confidence Intervals
Collagen Type III
Liver
Platelet Count
ROC Curve

Anti-TNF Therapy in Pregnant Women With Inflammatory Bowel Disease: Effects of Therapeutic Strategies on Disease Behavior and Birth Outcomes

Julsgaard, M., Hvas, C. L., Gearry, R. B., Gibson, P. R., Fallingborg, J., Sparrow, M. P., Bibby, B. M., Connell, W. R., Brown, S. J., Kamm, M. A., Lawrance, I. C., Vestergaard, T., Svenningsen, L., Baekdal, M., Kammerlander, H., Walsh, A., Boysen, T., Bampton, P., Radford-Smith, G., Kjeldsen, J. & 10 flere, Andrews, J. M., Subramaniam, K., Moore, G. T., Jensen, N. M., Connor, S. J., Wildt, S., Wilson, B., Ellard, K., Christensen, L. A. & Bell, S. J., 29. maj 2019, I : Inflammatory Bowel Diseases.

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Therapeutic Uses
Inflammatory Bowel Diseases
Pregnant Women
Tumor Necrosis Factor-alpha
Counseling

Autoimmun pankreatitis

Petersen, B. & Schaffalitzky, O. B., 11. nov. 2019, I : Ugeskrift for Laeger. 181, V07190398.

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Pancreatitis
Obstructive Jaundice
Rare Diseases
Diagnostic Errors
Pancreatic Neoplasms
90 Downloads (Pure)

Biochemical and histological characterisation of an experimental rodent model of non-alcoholic steatohepatitis – Effects of a peroxisome proliferator-activated receptor gamma (PPAR-γ) agonist and a glucagon-like peptide-1 analogue

Daniels, S. J., Leeming, D. J., Detlefsen, S., Bruun, M. F., Hjuler, S. T., Henriksen, K., Hein, P., Karsdal, M. A., Brockbank, S. & Cruwys, S., 1. mar. 2019, I : Biomedicine & Pharmacotherapy. 111, s. 926-933

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PPAR gamma
Fatty Liver
pioglitazone
Rodentia
Theoretical Models
44 Downloads (Pure)

Circulating levels of PRO-C3 reflect liver fibrosis and liver function in HIV positive patients receiving modern cART

Dold, L., Nielsen, M. J., Praktiknjo, M., Schwarze-Zander, C., Boesecke, C., Schierwagen, R., Mohr, R., Wasmuth, J-C., Jansen, C., Bischoff, J., Rockstroh, J. K., Karsdal, M. A., Spengler, U., Trebicka, J. & Leeming, D. J., 2019, I : PLOS ONE. 14, 7, 12 s., e0219526.

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liver cirrhosis
liver function
Liver Cirrhosis
Liver
HIV
31 Downloads (Pure)

Collagen type IV remodelling gender-specifically predicts mortality in decompensated cirrhosis

Lehmann, J., Praktiknjo, M., Nielsen, M. J., Schierwagen, R., Meyer, C., Thomas, D., Violi, F., Strassburg, C. P., Bendtsen, F., Møller, S., Krag, A., Karsdal, M. A., Leeming, D. J. & Trebicka, J., maj 2019, I : Liver International. 39, 5, s. 885-893

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Collagen Type IV
Transjugular Intrahepatic Portasystemic Shunt
Collagen Type III
Hepatic Veins
Portal Vein

Combination of CCL4 with alcoholic and metabolic injuries mimics human liver fibrosis

Galaxy Consortium, 1. aug. 2019, I : American Journal of Physiology - Gastrointestinal and Liver Physiology. 317, 2, s. G182-G194

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Liver Cirrhosis
Wounds and Injuries
Ethanol
Alcoholic Fatty Liver
Pharmaceutical Preparations
65 Downloads (Pure)

Combining liver stiffness with hyaluronic acid provides superior prognostic performance in chronic hepatitis C

Hansen, J. F., Christiansen, K. M., Staugaard, B., Moessner, B. K., Lillevang, S., Krag, A. & Christensen, P. B., 1. feb. 2019, I : PLOS ONE. 14, 2, 17 s., e0212036.

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chronic hepatitis C
hyaluronic acid
Chronic Hepatitis C
Hyaluronic Acid
Liver
70 Downloads (Pure)

Compartmentalization of Immune Response and Microbial Translocation in Decompensated Cirrhosis

Alvarez-Silva, C., Schierwagen, R., Pohlmann, A., Magdaleno, F., Uschner, F. E., Ryan, P., Vehreschild, M. J. G. T., Claria, J., Latz, E., Lelouvier, B., Arumugam, M. & Trebicka, J., feb. 2019, I : Frontiers in Immunology. 10, FEB, 11 s., 69.

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Interleukin-6
Bacterial DNA
Microbiota
Interleukin-8
Patient Advocacy

Cost-effectiveness of non-invasive screening for alcohol-related liver fibrosis

Galaxy Consortium, 8. okt. 2019, I : Hepatology (Baltimore, Md.).

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Liver Cirrhosis
Cost-Benefit Analysis
Quality-Adjusted Life Years
Alcohols
Liver

Disease course of inflammatory bowel disease unclassified in a European population-based inception cohort: An Epi-IBD study

Epi-IBD group, jun. 2019, I : Journal of Gastroenterology and Hepatology. 34, 6, s. 996-1003

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Inflammatory Bowel Diseases
Population
Ulcerative Colitis
Crohn Disease
Mesalamine

En million danskere har fedtlever. Her er 5 gode råd til at undgå bekymring og store undersøgelser

Gluud, L. L., Fialla, A. D. & Thiele, M., 14. okt. 2019, I : Videnskab.dk.

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Epidemiology and Effects of Bacterial Infections in Patients With Cirrhosis Worldwide

International Club of Ascites Global Study Group, 1. apr. 2019, I : Gastroenterology. 156, 5, s. 1368-1380.e10

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Epidemiology
North America
Hospital Mortality
Microbiology
Liver Transplantation

Extracellular Matrix Fragments of the Basement Membrane and the Interstitial Matrix Are Serological Markers of Intestinal Tissue Remodeling and Disease Activity in Dextran Sulfate Sodium Colitis

Lindholm, M., Manon-Jensen, T., Madsen, G. I., Krag, A., Karsdal, M. A., Kjeldsen, J. & Mortensen, J. H., nov. 2019, I : Digestive Diseases and Sciences. 64, 11, s. 3134-3142

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Dextran Sulfate
Colitis
Extracellular Matrix Proteins
Collagen Type III
Matrix Metalloproteinases

Fat-free muscle area measured by magnetic resonance imaging predicts overall survival of patients undergoing radioembolization of colorectal cancer liver metastases

Faron, A., Pieper, C. C., Schmeel, F. C., Sprinkart, A. M., Kuetting, D. L. R., Fimmers, R., Trebicka, J., Schild, H. H., Meyer, C., Thomas, D. & Luetkens, J. A., sep. 2019, I : European Radiology. 29, 9, s. 4709-4717

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Liver Neoplasms
Colorectal Neoplasms
Fats
Muscles
Liver

Fibroblast growth factor 21 is independently associated with severe hepatic steatosis in non-obese HIV-infected patients

Praktiknjo, M., Djayadi, N., Mohr, R., Schierwagen, R., Bischoff, J., Dold, L., Pohlmann, A., Schwarze-Zander, C., Wasmuth, J. C., Boesecke, C., Rockstroh, J. K. & Trebicka, J., aug. 2019, I : Liver International. 39, 8, s. 1514-1520

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HIV
Liver
fibroblast growth factor 21
Dyslipidemias
Hyperlipidemias
86 Downloads (Pure)

Home parenteral nutrition increases fat free mass in patients with incurable gastrointestinal cancer. Results of a randomized controlled trial

Obling, S. R., Wilson, B. V., Pfeiffer, P. & Kjeldsen, J., feb. 2019, I : Clinical Nutrition. 38, 1, s. 182-190

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Gastrointestinal Neoplasms
Randomized Controlled Trials
Fats
Quality of Life
Dietetics
Ulcerative Colitis
Inflammatory Bowel Diseases
Crohn Disease
Psoriatic Arthritis
Psoriasis

Liver Fibrosis and Metabolic Alterations in Adults With alpha-1-antitrypsin Deficiency Caused by the Pi*ZZ Mutation

European Alpha1-Liver Study Group, 1. sep. 2019, I : Gastroenterology. 157, 3, s. 705-719.e18

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alpha 1-Antitrypsin Deficiency
Liver Cirrhosis
Mutation
Liver
Liver Diseases

MAP(ASH): A new scoring system for the prediction of intervention and mortality in upper gastrointestinal bleeding

Redondo-Cerezo, E., Vadillo-Calles, F., Stanley, A. J., Laursen, S., Laine, L., Dalton, H. R., Ngu, J. H., Schultz, M. & Jiménez-Rosales, R., 29. jul. 2019, I : Journal of Gastroenterology and Hepatology (Australia).

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ROC Curve
Confidence Intervals
Databases
Interventional Radiology
Hospital Emergency Service

Meta-analysis of fecal metagenomes reveals global microbial signatures that are specific for colorectal cancer

Wirbel, J., Pyl, P. T., Kartal, E., Zych, K., Kashani, A., Milanese, A., Fleck, J. S., Voigt, A. Y., Palleja, A., Ponnudurai, R., Sunagawa, S., Coelho, L. P., Schrotz-King, P., Vogtmann, E., Habermann, N., Niméus, E., Thomas, A. M., Manghi, P., Gandini, S., Serrano, D. & 15 flere, Mizutani, S., Shiroma, H., Shiba, S., Shibata, T., Yachida, S., Yamada, T., Waldron, L., Naccarati, A., Segata, N., Sinha, R., Ulrich, C. M., Brenner, H., Arumugam, M., Bork, P. & Zeller, G., apr. 2019, I : Nature Medicine. 25, 4, s. 679-689

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Metagenome
Meta-Analysis
Colorectal Neoplasms
Genes
Microbiota

Natural disease course of Crohn's disease during the first 5 years after diagnosis in a European population-based inception cohort: an Epi-IBD study

Burisch, J., Kiudelis, G., Kupcinskas, L., Kievit, H. A. L., Andersen, K. W., Andersen, V., Salupere, R., Pedersen, N., Kjeldsen, J., D'Incà, R., Valpiani, D., Schwartz, D., Odes, S., Olsen, J., Nielsen, K. R., Vegh, Z., Lakatos, P. L., Toca, A., Turcan, S., Katsanos, K. H. & 27 flere, Christodoulou, D. K., Fumery, M., Gower-Rousseau, C., Zammit, S. C., Ellul, P., Eriksson, C., Halfvarson, J., Magro, F. J., Duricova, D., Bortlik, M., Fernandez, A., Hernández, V., Myers, S., Sebastian, S., Oksanen, P., Collin, P., Goldis, A., Misra, R., Arebi, N., Kaimakliotis, I. P., Nikuina, I., Belousova, E., Brinar, M., Cukovic-Cavka, S., Langholz, E., Munkholm, P. & Epi-IBD group, 1. mar. 2019, I : Gut. 68, 3, s. 423-433

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Crohn Disease
Population
Immunologic Factors
Eastern Europe
Mesalamine
6 Downloads (Pure)

Natural Disease Course of Ulcerative Colitis During the First Five Years of Follow-up in a European Population-based Inception Cohort-An Epi-IBD Study

Epi-IBD group, 1. feb. 2019, I : Journal of Crohn's and Colitis. 13, 2, s. 198–208

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Ulcerative Colitis
Population
Immunologic Factors
Colitis
Cohort Studies
13 Downloads (Pure)

Pathophysiological role of prostanoids in coagulation of the portal venous system in liver cirrhosis

Queck, A., Thomas, D., Jansen, C., Schreiber, Y., Rüschenbaum, S., Praktiknjo, M., Schwarzkopf, K. M., Mücke, M. M., Schierwagen, R., Uschner, F. E., Meyer, C., Clària, J., Zeuzem, S., Geisslinger, G., Trebicka, J. & Lange, C. M., 23. okt. 2019, I : PLOS ONE. 14, 10, 12 s., e0222840.

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liver cirrhosis
Portal Vein
Coagulation
coagulation
Liver Cirrhosis

Polymorphisms in the NFkB, TNF-alpha, IL-1beta, and IL-18 pathways are associated with response to anti-TNF therapy in Danish patients with inflammatory bowel disease

The Danish IBD Genetics Working Group, apr. 2019, I : Alimentary Pharmacology and Therapeutics. 49, 7, s. 890-903

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Interleukin-18
Inflammatory Bowel Diseases
Ulcerative Colitis
Tumor Necrosis Factor-alpha
Crohn Disease
44 Downloads (Pure)

Preemptive-TIPS improves outcome in high-risk variceal bleeding: An observational study

International Variceal Bleeding Observational Study Group and Baveno Cooperation, 1. jan. 2019, I : Hepatology (Baltimore, Md.). 69, 1, s. 282-293

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Transjugular Intrahepatic Portasystemic Shunt
Treatment Failure
Child Mortality
Hepatic Encephalopathy
Guidelines
General Practice
General Practitioners
Gastroscopy
Referral and Consultation
Denmark
67 Downloads (Pure)

Previous Use of Antithrombotic Agents Reduces Mortality and Length of Hospital Stay in Patients With High-risk Upper Gastrointestinal Bleeding

Dunne, P. D. J., Laursen, S. B., Laine, L., Dalton, H. R., Ngu, J. H., Schultz, M., Rahman, A., Anderloni, A., Murray, I. A. & Stanley, A. J., 1. feb. 2019, I : Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association. 17, 3, s. 440-447.e2

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Fibrinolytic Agents
Length of Stay
Interventional Radiology
Pharmaceutical Preparations
Melena
17 Downloads (Pure)

Prioritization of Therapeutic Targets and Trial Design in Cirrhotic Portal Hypertension

Abraldes, J. G., Trebicka, J., Chalasani, N., D'Amico, G., Rockey, D., Shah, V., Bosch, J. & Garcia-Tsao, G., 1. mar. 2019, I : Hepatology (Baltimore, Md.). 69, 3, s. 1287-1299

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Portal Hypertension
Portal Pressure
Phase III Clinical Trials
Clinical Trials, Phase I
Viscera
52 Downloads (Pure)

Rho-kinase inhibitor coupled to peptide-modified albumin carrier reduces portal pressure and increases renal perfusion in cirrhotic rats

Klein, S., Frohn, F., Magdaleno, F., Reker-Smit, C., Schierwagen, R., Schierwagen, I., Uschner, F. E., van Dijk, F., Fürst, D. O., Djudjaj, S., Boor, P., Poelstra, K., Beljaars, L. & Trebicka, J., 19. feb. 2019, I : Scientific Reports. 9, 11 s., 2256.

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Portal Pressure
rho-Associated Kinases
Albumins
Perfusion
Platelet-Derived Growth Factor beta Receptor
15 Downloads (Pure)

Sarcopenia is associated with development of acute-on-chronic liver failure in decompensated liver cirrhosis receiving transjugular intrahepatic portosystemic shunt

Praktiknjo, M., Clees, C., Pigliacelli, A., Fischer, S., Jansen, C., Lehmann, J., Pohlmann, A., Lattanzi, B., Krabbe, V. K., Strassburg, C. P., Arroyo, V., Merli, M., Meyer, C. & Trebicka, J., apr. 2019, I : Clinical and Translational Gastroenterology. 10, 4, 8 s., p e00025.

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Sarcopenia
Transjugular Intrahepatic Portasystemic Shunt
Liver Cirrhosis
Psoas Muscles
Hepatic Encephalopathy

Serological Assessment of the Quality of Wound Healing Processes in Crohn's Disease

Sun, S., Karsdal, M. A., Mortensen, J. H., Luo, Y., Kjeldsen, J., Krag, A., Jensen, M. D., Bay-Jensen, A. C. & Manon-Jensen, T., 1. jun. 2019, I : Journal of gastrointestinal and liver diseases : JGLD. 28, 2, s. 175-182

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Crohn Disease
Area Under Curve
Intestines
Peptides
Serum
5 Downloads (Pure)

Serum markers of type III and IV procollagen processing predict recurrence of fibrosis in liver transplanted patients

Nielsen, M. J., Villesen, I. F., Gudmann, N. S., Leeming, D. J., Krag, A., Karsdal, M. A., Zimmermann, T. & Schuppan, D., 16. okt. 2019, I : Scientific Reports. 9, 9 s., 14857.

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Collagen Type III
Liver Cirrhosis
Liver Transplantation
Physiologic Monitoring
Collagen Type V
9 Downloads (Pure)

Spleen stiffness to liver stiffness ratio significantly differs between ALD and HCV and predicts disease-specific complications

Elshaarawy, O., Mueller, J., Guha, I. N., Chalmers, J., Harris, R., Krag, A., Stæhr Madsen, B., Stefanescu, H., Farcau, O., Ardelean, A., Procopet, B., Thiele, M. & Mueller, S., aug. 2019, I : JHEP Reports. 1, 2, s. 99-106

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Statiner er sikre ved leversygdom og har muligvis en gunstig effekt

Balle Hugger, M., Bastrup Israelsen, M., Dalby Hansen, C. & Krag, A., 8. jul. 2019, I : Ugeskrift for Laeger. 181, V11180794.

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Hydroxymethylglutaryl-CoA Reductase Inhibitors
Liver Diseases
Liver
Wounds and Injuries
Enzymes
Helicobacter pylori
Cost-Benefit Analysis
Randomized Controlled Trials
Population
Quality-Adjusted Life Years
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Ulcerative Colitis
Adrenal Cortex Hormones
Pediatrics
Confidence Intervals
Proportional Hazards Models

Transient elastography for screening of liver fibrosis: cost-effectiveness analysis from six prospective cohorts in Europe and Asia

investigators of the LiverScreen Consortium, 27. aug. 2019, I : Journal of Hepatology.

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Liver Cirrhosis
Cost-Benefit Analysis
Liver Diseases
Quality-Adjusted Life Years
Liver

Trænger din lever til en måned uden fedt og alkohol?

Lindvig, K. P. & Thiele, M., 12. jan. 2019, I : Videnskab.dk.

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Epidemiologic Studies
Comorbidity
Incidence
Databases
Endoscopic Retrograde Cholangiopancreatography
2018
83 Downloads (Pure)

Accuracy of the Enhanced Liver Fibrosis Test vs Fibrotest, Elastography and Indirect Markers in Detection of Advanced Fibrosis in Patients with Alcoholic Liver Disease

Thiele, M., Madsen, B. S., Hansen, J. F., Detlefsen, S., Antonsen, S. & Krag, A., apr. 2018, I : Gastroenterology. 154, 5, s. 1369-1379

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Liver Cirrhosis
ROC Curve
Primary Health Care
Secondary Care Centers
Alcohols
69 Downloads (Pure)

Activation of RAAS in a rat model of liver cirrhosis: No effect of losartan on renal sodium excretion

Fialla, A. D., Schaffalitzky De Muckadell, O. B., Bie, P. & Thiesson, H. C., 19. sep. 2018, I : BMC Nephrology. 19, 8 s., 238.

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Losartan
Renin-Angiotensin System
Liver Cirrhosis
Renin
Placebos
109 Downloads (Pure)

Acute decompensation boosts hepatic collagen type III deposition and deteriorates experimental and human cirrhosis

Praktiknjo, M., Lehmann, J., Nielsen, M. J., Schierwagen, R., Uschner, F. E., Meyer, C., Thomas, D., Strassburg, C. P., Bendtsen, F., Møller, S., Krag, A., Karsdal, M. A., Leeming, D. J. & Trebicka, J., 2018, I : Hepatology communications. 2, 2, s. 211-222

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Collagen Type III
Liver Cirrhosis
Liver
Transjugular Intrahepatic Portasystemic Shunt
Ligation
125 Downloads (Pure)

Antifibrotic and molecular aspects of rifaximin in alcoholic liver disease: Study protocol for a randomized controlled trial

Madsen, B. S., Trebicka, J., Thiele, M., Israelsen, M., Arumugan, M., Havelund, T. & Krag, A., 26. feb. 2018, I : Trials. 19, 5 s., 143.

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Liver Cirrhosis
Randomized Controlled Trials
Microbiota
Liver Diseases
Placebos

Arterial lactate does not predict outcome better than existing risk scores in upper gastrointestinal bleeding

Stokbro, L. A., Schaffalitzky de Muckadell, O. B. & Laursen, S. B., maj 2018, I : Scandinavian Journal of Gastroenterology. 53, 5, s. 586-591

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Lactic Acid
Hospital Mortality
ROC Curve
Emergencies
Cohort Studies
98 Downloads (Pure)

Assessment of biopsy-proven liver fibrosis by two-dimensional shear wave elastography: An individual patient data based meta-analysis

Herrmann, E., de Lédinghen, V., Cassinotto, C., Chu, W. C-W., Leung, V. Y-F., Ferraioli, G., Filice, C., Castera, L., Vilgrain, V., Ronot, M., Dumortier, J., Guibal, A., Pol, S., Trebicka, J., Jansen, C., Strassburg, C. P., Zheng, R., Zheng, J., Francque, S., Vanwolleghem, T. & 11 flere, Vonghia, L., Manesis, E. K., Zoumpoulis, P., Sporea, I., Thiele, M., Krag, A., Cohen-Bacrie, C., Criton, A., Gay, J., Deffieux, T. & Friedrich-Rust, M., jan. 2018, I : Hepatology. 67, 1, s. 260–272

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Liver Cirrhosis
Meta-Analysis
Hepatitis B
ROC Curve
Chronic Hepatitis C

Association between early ERCP and mortality in patients with acute cholangitis

Tan, M., Schaffalitzky de Muckadell, O. B. & Laursen, S. B., jan. 2018, I : Gastrointestinal Endoscopy. 87, 1, s. 185-192

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Endoscopic Retrograde Cholangiopancreatography
Medical Records
Denmark
Logistic Models
Odds Ratio
35 Downloads (Pure)

Association Between Grade of Acute on Chronic Liver Failure and Response to Terlipressin and Albumin in Patients With Hepatorenal Syndrome

EASL CLIF Consortium, European Foundation for the Study of Chronic Liver Failure (EF Clif), nov. 2018, I : Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association. 16, 11, s. 1792-1800.e3

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Hepatorenal Syndrome
Albumins
Creatinine
Acute-On-Chronic Liver Failure
terlipressin
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Association Between Portosystemic Shunts and Increased Complications and Mortality in Patients With Cirrhosis

Simón-Talero, M., Roccarina, D., Martínez, J., Lampichler, K., Baiges, A., Low, G., Llop, E., Praktiknjo, M., Maurer, M. H., Zipprich, A., Triolo, M., Vangrinsven, G., Garcia-Martinez, R., Dam, A., Majumdar, A., Picón, C., Toth, D., Darnell, A., Abraldes, J. G., Lopez, M. & 31 flere, Kukuk, G., Krag, A., Bañares, R., Laleman, W., La Mura, V., Ripoll, C., Berzigotti, A., Trebicka, J., Calleja, J. L., Tandon, P., Hernandez-Gea, V., Reiberger, T., Albillos, A., Tsochatzis, E. A., Augustin, S., Genescà, J., Quiroga, S., Yu, D., Mandorfer, M., Garcia-Pagan, J. C., Berbel, C., Ferrusquia, J., Ble, M., Garcia-Criado, M. A., Belmonte, E., Ney, M., Margini, C., Casu, S., Murgia, G., Ludwig, C. & Baveno VI-SPSS group from the Baveno Cooperation, Baveno VI-SPSS group, maj 2018, I : Gastroenterology. 154, 6, s. 1694-1705.e4

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Hepatic Encephalopathy
Liver Diseases
Liver
Confidence Intervals
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