• J.B. Winsløws Vej 9, indgang B, 1. Sal

    5000 Odense C

Publikationer 1970 2019

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Tidsskriftartikel
2019
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A Cohort Comparison of Lifespan After Age 100 in Denmark and Sweden: Are Only the Oldest Getting Older?

Medford, A., Christensen, K., Skytthe, A. & Vaupel, J. W., apr. 2019, I : Demography. 56, 2, s. 665-677

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life-span
Denmark
Swede
Sweden
trend
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Advanced parental age at conception and sex affects mitochondrial DNA copy number in human and fruit flies

Mengel-From, J., Svane, A. M., Pertoldi, C., Kristensen, T. N., Loeschcke, V., Skytthe, A., Christensen, K., Lindahl-Jacobsen, R., Hjelmborg, J. & Christiansen, L., 13. nov. 2019, I : The journals of gerontology. Series A, Biological sciences and medical sciences. 74, 12, s. 1853-1860

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Fruit
Parents
Maternal Age
Health
Drosophila melanogaster
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Age‐dependent DNA methylation patterns on the Y chromosome in elderly males

Lund, J. B., Li, S., Christensen, K., Mengel-From, J., Thinggaard, M. S., Marioni, R. E., Starr, J., Pattie, A., Deary, I. J., Baumbach, J. & Tan, Q., 2019, I : Aging Cell. 8 s.

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DNA Methylation
Epigenomics
Sex Characteristics
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A meta-analysis of genome-wide association studies identifies multiple longevity genes

Deelen, J., Evans, D. S., Arking, D. E., Tesi, N., Nygaard, M., Liu, X., Wojczynski, M. K., Biggs, M. L., van der Spek, A., Atzmon, G., Ware, E. B., Sarnowski, C., Smith, A. V., Seppälä, I., Cordell, H. J., Dose, J., Amin, N., Arnold, A. M., Ayers, K. L., Barzilai, N. & 64 flere, Becker, E. J., Beekman, M., Blanché, H., Christensen, K., Christiansen, L., Collerton, J. C., Cubaynes, S., Cummings, S. R., Davies, K., Debrabant, B., Deleuze, J. F., Duncan, R., Faul, J. D., Franceschi, C., Galan, P., Gudnason, V., Harris, T. B., Huisman, M., Hurme, M. A., Jagger, C., Jansen, I., Jylhä, M., Kähönen, M., Karasik, D., Kardia, S. L. R., Kingston, A., Kirkwood, T. B. L., Launer, L. J., Lehtimäki, T., Lieb, W., Lyytikäinen, L. P., Martin-Ruiz, C., Min, J., Nebel, A., Newman, A. B., Nie, C., Nohr, E. A., Orwoll, E. S., Perls, T. T., Province, M. A., Psaty, B. M., Raitakari, O. T., Reinders, M. J. T., Robine, J. M., Rotter, J. I., Sebastiani, P., Smith, J., Sørensen, T. I. A., Taylor, K. D., Uitterlinden, A. G., van der Flier, W., van der Lee, S. J., van Duijn, C. M., van Heemst, D., Vaupel, J. W., Weir, D., Ye, K., Zeng, Y., Zheng, W., Holstege, H., Kiel, D. P., Lunetta, K. L., Slagboom, P. E. & Murabito, J. M., 1. dec. 2019, I : Nature Communications. 10, 1, 14 s., 3669.

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genome
Genome-Wide Association Study
genes
Meta-Analysis
Genes
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A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer's disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity

Sørensen, T. I. A. & DESGESCO (Dementia Genetics Spanish Consortium), EADB (Alzheimer Disease European DNA biobank), aug. 2019, I : Acta Neuropathologica. 138, 2, s. 237-250

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Lewy Body Disease
Alzheimer Disease
Mutation
Neurodegenerative Diseases
Alleles

A novel healthy metabolic phenotype developed among a cohort of families enriched for longevity

Long Life Family Study, 2019, I : Metabolism: Clinical and Experimental. 94, s. 28-38

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Lung
Cognition
Fasting
Insulin
Metabolic Networks and Pathways

APOE Alleles and Extreme Human Longevity

Sebastiani, P., Gurinovich, A., Nygaard, M., Sasaki, T., Sweigart, B., Bae, H., Andersen, S. L., Villa, F., Atzmon, G., Christensen, K., Arai, Y., Barzilai, N., Puca, A., Christiansen, L., Hirose, N. & Perls, T. T., 1. jan. 2019, I : The journals of gerontology. Series A, Biological sciences and medical sciences. 74, 1, s. 44–51

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Alleles
Population
New England
Retirement
Genetic Models
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Associations of Mitochondrial and Nuclear Mitochondrial Variants and Genes with Seven Metabolic Traits

Kraja, A. T., Liu, C., Fetterman, J. L., Graff, M., Have, C. T., Gu, C., Yanek, L. R., Feitosa, M. F., Arking, D. E., Chasman, D. I., Young, K., Ligthart, S., Hill, W. D., Weiss, S., Luan, J., Giulianini, F., Li-Gao, R., Hartwig, F. P., Lin, S. J., Wang, L. & 132 flere, Richardson, T. G., Yao, J., Fernandez, E. P., Ghanbari, M., Wojczynski, M. K., Lee, W-J., Argos, M., Armasu, S. M., Barve, R. A., Ryan, K. A., An, P., Baranski, T. J., Bielinski, S. J., Bowden, D. W., Broeckel, U., Christensen, K., Chu, A. Y., Corley, J., Cox, S. R., Uitterlinden, A. G., Rivadeneira, F., Cropp, C. D., Daw, E. W., van Heemst, D., de Las Fuentes, L., Gao, H., Tzoulaki, I., Ahluwalia, T. S., de Mutsert, R., Emery, L. S., Erzurumluoglu, A. M., Perry, J. A., Fu, M., Forouhi, N. G., Gu, Z., Hai, Y., Harris, S. E., Hemani, G., Hunt, S. C., Irvin, M. R., Jonsson, A. E., Justice, A. E., Kerrison, N. D., Larson, N. B., Lin, K-H., Love-Gregory, L. D., Mathias, R. A., Lee, J. H., Nauck, M., Noordam, R., Ong, K. K., Pankow, J., Patki, A., Pattie, A., Petersmann, A., Qi, Q., Ribel-Madsen, R., Rohde, R., Sandow, K., Schnurr, T. M., Sofer, T., Starr, J. M., Taylor, A. M., Teumer, A., Timpson, N. J., de Haan, H. G., Wang, Y., Weeke, P. E., Williams, C., Wu, H., Yang, W., Zeng, D., Witte, D. R., Weir, B. S., Wareham, N. J., Vestergaard, H., Turner, S. T., Torp-Pedersen, C., Stergiakouli, E., Sheu, W. H-H., Rosendaal, F. R., Ikram, M. A., Franco, O. H., Ridker, P. M., Perls, T. T., Pedersen, O., Nohr, E. A., Newman, A. B., Linneberg, A., Langenberg, C., Kilpeläinen, T. O., Kardia, S. L. R., Jørgensen, M. E., Jørgensen, T., Sørensen, T. I. A., Homuth, G., Hansen, T., Goodarzi, M. O., Deary, I. J., Christensen, C., Chen, Y-D. I., Chakravarti, A., Brandslund, I., Bonnelykke, K., Taylor, K. D., Wilson, J. G., Rodriguez, S., Davies, G., Horta, B. L., Thyagarajan, B., Rao, D. C., Grarup, N., Davila-Roman, V. G., Hudson, G., Guo, X., Arnett, D. K., Hayward, C., Vaidya, D., Mook-Kanamori, D. O., Tiwari, H. K., Levy, D., Loos, R. J. F., Dehghan, A., Elliott, P., Malik, A. N., Scott, R. A., Becker, D. M., de Andrade, M., Province, M. A., Meigs, J. B., Rotter, J. I. & North, K. E., 3. jan. 2019, I : American Journal of Human Genetics. 104, 1, s. 112-138

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Mitochondrial Genes
Body Mass Index
Insulin
Adipocytes
Type 2 Diabetes Mellitus

Birth dimensions, severe mental illness and risk of type 2 diabetes in a cohort of Danish men born in 1953

Garriga, M., Wium-Andersen, M. K., Wium-Andersen, I. K., Nordentoft, M. & Osler, M., 1. okt. 2019, I : European Psychiatry. 62, s. 1-9

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Type 2 Diabetes Mellitus
Weights and Measures
Oral Diagnosis
Low Birth Weight Infant
Proportional Hazards Models

Brief Assessment of Impaired Cognition (BASIC)-Validation of a new dementia case-finding instrument integrating cognitive assessment with patient and informant report

Jørgensen, K., Nielsen, T. R., Nielsen, A., Waldorff, F. B., Høgh, P., Jakobsen, S., Gottrup, H., Vestergaard, K. & Waldemar, G., nov. 2019, I : International Journal of Geriatric Psychiatry. 34, 11, s. 1724-1733

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Cognition
General Practice
Research
Cognitive Dysfunction

Clonal hematopoiesis in elderly twins: concordance, discordance and mortality

Hansen, J. W., Pedersen, D. A., Larsen, L. A., Husby, S., Clemmensen, S. B., Hjelmborg, J., Favero, F., Weischenfeldt, J., Christensen, K. & Grønbæk, K., 24. okt. 2019, I : Blood.

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Mutation
Twin Studies
Dizygotic Twins
Monozygotic Twins
Mutation Rate

Declining cancer incidence at the oldest ages: Hallmark of aging or lower diagnostic activity?

Pedersen, J. K., Rosholm, J-U., Ewertz, M., Engholm, G., Lindahl-Jacobsen, R. & Christensen, K., sep. 2019, I : Journal of Geriatric Oncology. 10, 5, s. 792-798

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Incidence
Neoplasms
Skin Neoplasms
Denmark
Colon

Deletions and loss-of-function variants in TP63 associated with orofacial clefting

Khandelwal, K. D., van den Boogaard, M-J. H., Mehrem, S. L., Gebel, J., Fagerberg, C., van Beusekom, E., van Binsbergen, E., Topaloglu, O., Steehouwer, M., Gilissen, C., Ishorst, N., van Rooij, I. A. L. M., Roeleveld, N., Christensen, K., Schoenaers, J., Bergé, S., Murray, J. C., Hens, G., Devriendt, K., Ludwig, K. U. & 6 flere, Mangold, E., Hoischen, A., Zhou, H., Dötsch, V., Carels, C. E. L. & van Bokhoven, H., jul. 2019, I : European Journal of Human Genetics. 27, 7, s. 1101-1112

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Alleles
Population Control
Penetrance
Nonsense Codon
Mutant Proteins
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Diagnosing heart failure in centenarians

Rasmussen, S. H., Andersen-Ranberg, K., Dahl, J., Nybo, M., Jeune, B., Christensen, K. & Gill, S., 1. jan. 2019, I : Journal of Geriatric Cardiology. 16, 1, s. 1-11

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Brain Natriuretic Peptide
Echocardiography
Population
Denmark
Left Ventricular Function

Electroconvulsive therapy and later stroke in patients with affective disorders

Rozing, M. P., Jorgensen, M. B. & Osler, M., 1. mar. 2019, I : British Journal of Psychiatry. 214, 3, s. 168-170

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Electroconvulsive Therapy
Social Adjustment
Propensity Score
Registries
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Epigenome-wide association study of depression symptomatology in elderly monozygotic twins

Starnawska, A., Tan, Q., Sørensen, M., McGue, M., Mors, O., Børglum, A. D., Christensen, K., Nyegaard, M. & Christiansen, L., 2. sep. 2019, I : Translational Psychiatry. 9, 1, 14 s., 214.

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Monozygotic Twins
Depression
DNA Methylation
Epigenomics
Flow Cytometry

Gender differences in cognitive function and grip strength: a cross-national comparison of four European regions

Ahrenfeldt, L. J., Scheel-Hincke, L. L., Kjærgaard, S., Möller, S., Christensen, K. & Lindahl-Jacobsen, R., 1. aug. 2019, I : European Journal of Public Health. 29, 4, s. 667-674

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Cognition
Sex Characteristics
Linear Models
Health
Retirement
Monozygotic Twins
Immune System Diseases
Transcriptome
Individuality
Cognition

Hearing loss, cognitive ability, and dementia in men age 19–78 years

Osler, M., Christensen, G. T., Mortensen, E. L., Christensen, K., Garde, E. & Rozing, M. P., feb. 2019, I : European Journal of Epidemiology. 34, 2, s. 125-130

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International Classification of Diseases
Registries
Depression
Physicians
Education

Heterogeneity of healthy aging: comparing long-lived families across five healthy aging phenotypes of blood pressure, memory, pulmonary function, grip strength, and metabolism

for the Long Life Family Study, aug. 2019, I : GeroScience. 41, 4, s. 383-393

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Lung
Fasting
Body Mass Index
Insulin
Lipids
20 Downloads (Pure)

Incidence of primary spontaneous pneumothorax: a validated, register-based nationwide study

Olesen, W. H., Titlestad, I. L., Andersen, P. E., Lindahl-Jacobsen, R. & Licht, P. B., apr. 2019, I : ERJ Open Research. 5, 2, 19 s.

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Pneumothorax
Incidence
Population
Registries
Primary Spontaneous Pneumothorax
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Independent associations of TOMM40 and APOE variants with body mass index

Long Life Family Study Research Group, 1. feb. 2019, I : Aging Cell. 18, 1, 10 s., e12869.

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Body Mass Index
Alleles
Heterozygote
Alzheimer Disease
Confidence Intervals
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Intergenerational relations and social mobility: Social inequality in physical function in old age

Jørgensen, T. S. H., Nilsson, C. J., Lund, R., Siersma, V. & Fors, S., 1. jan. 2019, I : Archives of Gerontology and Geriatrics. 80, s. 58-64

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Intergenerational Relations
Occupations
Linear Models
Health
Parents
52 Downloads (Pure)

Is the age difference between partners related to women's earnings?

Corollo, A., Oksuzyan, A., Drefahl, S., Camarda, C. G., Juel Ahrenfeldt, L., Christensen, K. & van Raalte, A., jul. 2019, I : Demographic Research. 41, s. 425-460 15.

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age difference
income
Denmark
husband
career
Åben adgang
Proxy
Longitudinal Studies
Registries
Cohort Studies
Surveys and Questionnaires

Longitudinal Associations of Sensory and Cognitive Functioning: A Structural Equation Modeling Approach

de la Fuente, J., Hjelmborg, J., Wod, M., de la Torre-Luque, A., Caballero, F. F., Christensen, K. & Ayuso-Mateos, J. L., 4. okt. 2019, I : Journals of Gerontology. Series B: Psychological Sciences & Social Sciences. 74, 8, s. 1308-1316

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visual impairment
hearing impairment
old age
Hearing
cognition
64 Downloads (Pure)

Longitudinal changes in the genetic and environmental influences on the epigenetic clocks across old age: Evidence from two twin cohorts

Jylhävä, J., Hjelmborg, J., Sørensen, M., Munoz, E., Tan, Q., Kuja-Halkola, R., Mengel-From, J., Christensen, K., Christiansen, L., Hägg, S., Pedersen, N. L. & Reynolds, C. A., feb. 2019, I : EBioMedicine. 40, s. 710-716

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Epigenomics
Clocks
Research
DNA Methylation
Epidemiology
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Low-level cognitive ability in young adulthood and other risk factors of depression in an observational cohort study among deployed Danish soldiers

Nissen, L. R., Karstoft, K. I., Vedtofte, M. S., Nielsen, A. B. S., Osler, M., Mortensen, E. L., Christensen, G. T. & Andersen, S. B., 3. apr. 2019, I : Social Psychiatry and Psychiatric Epidemiology. 54, 4, s. 497-506

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Military Personnel
cognitive ability
soldier
adulthood
Cohort Studies

Mobility limitation as determinant of primary care use and ambulatory care sensitive conditions

Jørgensen, T. S. H., Siersma, V., Lund, R. & Nilsson, C. J., 15. feb. 2019, I : European Geriatric Medicine. 10, 1, s. 53-60

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Primary Health Care
General Practitioners
Referral and Consultation
Incidence
House Calls
24 Downloads (Pure)

Multi-ancestry genome-wide gene–smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids

Understanding Society Scientific Group, Lifelines Cohort, COGENT-Kidney Consortium & EPIC-InterAct Consortium, apr. 2019, I : Nature Genetics. 51, 4, s. 636-648

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Smoking
Lipids
Serum
LDL Cholesterol
Meta-Analysis
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Older multimorbid patients' experiences on integration of services: a systematic review

Boye, L. K., Mogensen, C. B., Mechlenborg, T., Waldorff, F. B. & Andersen, P. T., 5. nov. 2019, I : BMC Health Services Research. 19, 9 s., 795.

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Comorbidity
Delivery of Health Care
Health Services
Frustration
Population
Life Expectancy
Health
Population

Prevalence, Incidence and Risk Factors for Overall, Physical and Cognitive Independence among those from exceptionally long-lived families: The Long Life Family Study

Santanasto, A. J., Marron, M. M., Boudreau, R. M., Feitosa, M. F., Wojczynski, M. K., Arbeev, K. G., Thyagarajan, B., Schupf, N., Stallard, E., Sebastiani, P., Cosentino, S., Christensen, K. & Newman, A. B., 14. maj 2019, I : The journals of gerontology. Series A, Biological sciences and medical sciences.

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Survivors
Incidence
Lung
Neoplasms
Advanced Glycosylation End Product-Specific Receptor
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Risk-Taking
Health
Smoking
Health Behavior
Denmark

Resting heart rate and mortality in the very old

Wod, M., Jensen, M. T., Galatius, S., Hjelmborg, J. B., Jensen, G. B. & Christensen, K., dec. 2019, I : Scandinavian Journal of Clinical & Laboratory Investigation. 79, 8, s. 566-571

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Population
Palpation
Survival Analysis
Proportional Hazards Models
Cohort Studies
54 Downloads (Pure)

Sex and age specific reduction in stress resistance and mitochondrial DNA copy number in Drosophila melanogaster

Kristensen, T. N., Loeschcke, V., Tan, Q., Pertoldi, C. & Mengel-From, J., 23. aug. 2019, I : Scientific Reports. 9, 7 s., 12305.

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stress tolerance
Drosophila melanogaster
mitochondrial DNA
gender
age structure

Sex Differences in Comorbidity and Frailty in Europe

Ahrenfeldt, L. J., Möller, S., Thinggaard, M., Christensen, K. & Lindahl-Jacobsen, R., sep. 2019, I : International Journal of Public Health. 64, 7, s. 1025-1036

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Sex Characteristics
Comorbidity
Retirement
Health Surveys
Cross-Sectional Studies

Socioeconomic Position Across the Life Course and Cognitive Ability Later in Life: The Importance of Considering Early Cognitive Ability

Foverskov, E., Mortensen, E. L., Holm, A., Pedersen, J. L. M., Osler, M. & Lund, R., 1. jul. 2019, I : Journal of Aging and Health. 31, 6, s. 947-966

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Individuality
29 Downloads (Pure)

The AgeGuess database, an open online resource on chronological and perceived ages of people aged 5-100

Jones, J. A. B., Nash, U. W., Vieillefont, J., Christensen, K., Misevic, D. & Steiner, U. K., 31. okt. 2019, I : Scientific Data. 6, 8 s., 246.

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Aging of materials
Resources
Biomarkers
resources
Guess

The association between depressive mood and ischemic heart disease: a twin study

Wium-Andersen, M. K., Wium-Andersen, I. K., Jørgensen, M. B., McGue, M., Jørgensen, T. S. H., Christensen, K. & Osler, M., sep. 2019, I : Acta Psychiatrica Scandinavica. 140, 3, s. 265-274

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Twin Studies
Depression
Social Adjustment
Dizygotic Twins
Monozygotic Twins

The Effect of Economic Assets on Mortality in Patients with Dementia: A Population-Based Cohort Study

Bebe, A., Siersma, V., Kragstrup, J., Nielsen, A. B. S., Møller, A., Søndergaard, J., Rós Nicolaisdóttir, D. & Waldorff, F. B., 2. feb. 2019, I : Journal of Alzheimer's disease : JAD. 67, 4, s. 1245-1253

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Cohort Studies
Population
Incidence
Proportional Hazards Models
Imagining
Memoir
Coexistence
Close Reading
Visible

The real facts supporting Jeanne Calment as the oldest ever human

Robine, J-M., Allard, M., Herrmann, F. R. & Jeune, B., 13. nov. 2019, I : The journals of gerontology. Series A, Biological sciences and medical sciences. 74, 1, s. S13-S20

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Nuclear Family
Documentation
Publications
Theoretical Models
Mothers

Traumatic brain injury and risk of dementia at different levels of cognitive ability and education

Osler, M., Rozing, M. P., Eliasen, M., Christensen, K. & Mortensen, E. L., 2019, I : European Journal of Neurology.

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Education
Registries
Confidence Intervals
Prescriptions
Comorbidity

Trends in Hospital Deaths in Denmark from 1980 to 2014, at Ages 50 and Older

Carollo, A., Verdiell, N. C., Hale, J. M., Andersen-Ranberg, K., Lindahl-Jacobsen, R. & Oksuzyan, A., mar. 2019, I : Journal of the American Geriatrics Society. 67, 3, s. 471-476

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Denmark
Spouses
Registries
Inpatients
Retrospective Studies

Use of β2-adrenoreceptor agonist and antagonist drugs and risk of Parkinson disease

Hopfner, F., Wod, M., Höglinger, G. U., Blaabjerg, M., Rösler, T. W., Kuhlenbäumer, G., Christensen, K., Deuschl, G. & Pottegård, A., 9. jul. 2019, I : Neurology. 93, 2, s. e135-e142

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Parkinson Disease
Pharmaceutical Preparations
Odds Ratio
Confidence Intervals
Chronic Obstructive Pulmonary Disease
Quality of Health Care
Life Expectancy
Quality of Life
Delivery of Health Care
Family Physicians
2018

A bidirectional association between cognitive ability in young adulthood and epilepsy: a population-based cohort study

Osler, M., Mortensen, E. L., Christensen, K. & Christensen, G. T., 1. aug. 2018, I : International Journal of Epidemiology. 47, 4, s. 1151–1158

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Cohort Studies
Population
International Classification of Diseases
Registries
Databases

A Cross-National Study of the Gender Gap in Health Among Older Adults in India and China: Similarities and Disparities

Oksuzyan, A., Singh, P. K., Christensen, K. & Jasilionis, D., 3. nov. 2018, I : The Gerontologist. 58, 6, s. 1156–1165

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Åben adgang
China
Health
Confidence Intervals
Cognition
Logistic Models

Age-moderation of genetic and environmental contributions to cognitive functioning in mid- and late-life for specific cognitive abilities

Pahlen, S., Hamdi, N. R., Dahl Aslan, A. K., Horwitz, B. N., Panizzon, M. S., Petersen, I., Zavala, C., Christensen, K., Finkel, D., Franz, C. E., Gatz, M., Johnson, W., Kremen, W. S., Krueger, R. F., Neiderhiser, J. M., Reynolds, C. A., Pedersen, N. L. & McGue, M., 1. maj 2018, I : Intelligence. 68, s. 70-81

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Vocabulary
Denmark
Age Groups
Moderation
Cognitive Ability