Fine needle aspiration biopsy of salivary gland lesions.: Evaluation of the preoperative information

  • Kristine Bjørndal (Foredragsholder)

Aktivitet: Foredrag og mundtlige bidragForedrag og præsentationer i privat eller offentlig virksomhed




Bjørndal K.¹, Christensen RK², Godballe C¹, Krogdahl A².

From the Departments of ¹ENT Head & Neck Surgery and ²Clinical Pathology, Odense University Hospital, Denmark.


Objective: To estimate the reliability of fine needle aspiration biopsy (FNA) in the diagnostic set up of salivary gland lesions.


Method: 879 patients with a total of 1073 FNA´s from a salivary gland lesion during the period from 1.1.1997 to 31.12.2006 at Odense University Hospital (OUH) were retrospectively included for the study. The referral area was the county of Funen, with a population of 500.000 inhabitants. FNA´s were received from the Department of ENT Head and Neck Surgery, OUH and from ENT Head and Neck surgeons in private practices. All FNA´s were air dried and stained with May-Grünewald-Giemsa and evaluated at the Department of Clinical Pathology, OUH.  The cytological diagnosis and the corresponding histology were compared.


Results: In 382 patients the salivary gland lesion were diagnosed with both cytology and histology. 245  patients had a benign tumour by cytology and 241 (98%) of these had it confirmed by histology. 45 patients had a malignant tumour by cytology and 44 (98%) had it confirmed by histology. The sensitivity and specificity was 83% and 99.7%, respectively. The positive predictive value was 98% and the negative predictive value was 97%. The overall accuracy of FNA was 92.6%. The correct subtyping of benign lesions were 97% and the exact type specific concordance of the malignant ones were 71%.


Conclusion: It is concluded, that fine needle aspiration biopsy of salivary gland lesions a reliable method which adds significant diagnostic information to the clinician.

Periode18. apr. 2008
BegivenhedstitelThe Annual Meeting of Scandinavian Society for Head and Neck Oncology 17-19 April 2008
PlaceringTurku, Finland